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Ginsenosides
Views 1634
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229 Diseases Researched for Ginsenosides
Name
AC
CK
Focus
Oxidative Stress
31
60
Lung Cancer
28
45
Alzheimer's Disease
27
41
Liver Cancer
27
40
Lipopolysaccharide-Induced Toxicity
27
39
Inflammation
25
36
Depression
15
29
Myocardial Ischemia
11
28
Cancers: All
15
27
Stroke: Ischemic
5
25
Brain Ischemia
8
23
Breast Cancer
18
22
Cerebral Ischemia
13
22
Chemically-Induced Liver Damage
11
21
Colorectal Cancer
12
21
Memory Disorders
10
20
Cancers: Drug Resistant
9
19
Diabetic Complications
9
16
Cognitive Decline/Dysfunction
8
15
Leukemia: Acute myelogenous leukemia (AML)
5
15
Ovarian Cancer
12
15
Stroke
4
15
Chemotherapy-Induced Toxicity: Cisplatin
8
14
HIV Infections
4
14
Obesity
10
14
Acetaminophen (Tylenol) Toxicity
7
13
Carcinoma: Non-Small-Cell Lung
3
13
DNA damage
4
13
Melanoma
10
13
Athletic Performance
2
12
Diabetes Mellitus: Type 2
8
12
Hypoxia
8
12
Spinal Cord Injuries
7
12
Aging Skin
2
11
Cancer Metastasis
10
11
Radiation Induced Illness
2
11
Wound Healing
6
11
Brain Inflammation
6
10
Cardiovascular Diseases
7
10
Chronic Kidney Disease (CKD)
1
10
Colon Cancer
9
10
Dry Eye Syndromes
1
10
Neurodegenerative Diseases
8
10
Osteoarthritis
4
10
Hair Loss
4
9
Aging: Brain
4
8
Chemotherapy-Induced Toxicity: Doxorubicin
5
8
Endometriosis
4
8
High Fat Diet
4
8
Myocardial Infarction
4
8
Atherosclerosis
4
7
Glioblastoma
4
7
Insulin Resistance
5
7
Leukemia
6
7
Lung Injury: Acute
4
7
Sepsis
5
7
Skin Cancer
6
7
Ultraviolet Radiation Induced Damage
6
7
Aging
3
6
Breast Cancer: Triple Negative
5
6
Cardiac Hypertrophy
3
6
Colitis
3
6
Fatigue
3
6
Hydrogen Peroxide Induced Toxicity
5
6
Hypertension
3
6
Ischemia
4
6
Liver Fibrosis
3
6
Nonalcoholic fatty liver disease (NAFLD)
3
6
Prostate Cancer
6
6
Squamous cell carcinoma
5
6
Brain: Microglial Activation
4
5
Chemotherapy-Induced Toxicity: Cyclophosphamide
3
5
Diabetes Mellitus: Type 1
3
5
Erectile Dysfunction
3
5
Learning disorders
3
5
Lipid Peroxidation
3
5
Lung Injury: Smoke-Induced
3
5
Pancreatic Cancer
3
5
Parkinson's Disease
5
5
Scars
3
5
Stroke: Attenuation/Recovery
3
5
Anxiety
2
4
Atopic Dermatitis
2
4
Burns
2
4
Cervical Cancer
4
4
Dermatitis
2
4
Diabetes: Cognitive Dysfunction
2
4
Diabetic Nephropathy
2
4
Diabetic Retinopathy
2
4
Esophageal Cancer
3
4
Fatigue: Excercise-Induced
2
4
Glioma
4
4
Heart Failure
2
4
Hyperglycemia
3
4
Hypertension: Pulmonary
2
4
Intestinal Ischemia
2
4
Liver Damage
3
4
Osteoporosis
3
4
Sleep Disorders
2
4
Staphylococcus aureus infection
2
4
Autoimmune Diseases
2
3
Dementia
2
3
Gallbladder Cancer
2
3
Gastric Cancer
3
3
Huntington Disease
2
3
Inflammatory Bowel Diseases
2
3
Liver Cirrhosis
2
3
Multiple Myeloma
3
3
Osteosarcoma
3
3
Promyelocytic leukemia
3
3
Tertiary butyl hydroperoxide toxicity
2
3
Thyroid Cancer
2
3
Acute Myeloid Leukemia
2
2
Adiponectin: Low Levels
1
2
Air Pollution Linked Toxicity
1
2
Alcoholic Liver Disease
1
2
Anemia
1
2
Aneurysm: Aortic
1
2
Attention Deficit Disorder with Hyperactivity
1
2
Brain: Oxidative Stress
1
2
Cardiomyopathy
1
2
Cerebral Aneurysm
1
2
Chemobrain
1
2
Chemotherapy-Induced Neurotoxicity
1
2
Chemotherapy-Induced Toxicity: 5-fluorouracil
1
2
Chemotherapy-Induced Toxicity: Bleomycin
1
2
Chronic Obstructive Pulmonary Disease
1
2
Coxsackievirus Infections
2
2
Depression
1
2
Diabetes: Cardiovascular Illness
1
2
Diabetes: Oxidative Stress
1
2
Drug Toxicity: Cephaloridine
1
2
Dysmenorrhea
1
2
Encephalomyelitis
1
2
Encephalopathy
1
2
Endometrial Cancer
2
2
Exercise-Induced Tissue Damage
1
2
Fatigue: Cancer-Associated
1
2
H1N1 Infection
1
2
Hashimoto's thyroiditis
1
2
Hearing Loss: Noise-Induced
1
2
Hepatic Steatosis
1
2
Herbicide Toxicity
1
2
Hypercapnia
1
2
Hyperlipidemia
1
2
Hypoglycemia
1
2
Influenza A
1
2
Ischemia: Myocardial
1
2
Itching
1
2
Keloid
1
2
Kidney Failure: Acute
1
2
Kidney Fibrosis
1
2
Liver Failure: Acute
1
2
Low Libido
1
2
Low Testosterone
1
2
Mastitis
1
2
Memory Disorders: Drug-Induced
1
2
Middle Cerebral Artery Occlusion (MCAO)
1
2
Mitochondrial Diseases
2
2
Morphine Tolerance/Dependence
1
2
Multiple Sclerosis
1
2
Muscle Atrophy
2
2
Myocardial Fibrosis
1
2
Nerve Injuries
1
2
Neuroblastoma
2
2
Obstructive Nephropathy
1
2
Ovarian Failure
1
2
Pain
1
2
Postoperative Recovery
1
2
Psoriasis
1
2
Rheumatoid Arthritis
1
2
Right Ventricular Hypertrophy
1
2
Rotavirus Infections
1
2
Sciatica
1
2
Smoking: Pulmonary
1
2
Subarachnoid hemorrhage
1
2
Acute T cell Leukemias
1
1
Acute lymphoblastic leukemia (ALL)
1
1
Alcohol Toxicity
1
1
Alopecia
1
1
Aluminum Toxicity
1
1
Amyotrophic lateral sclerosis (ALS)
1
1
Asthma
1
1
Benzo[a]pyrene-induced Toxicity
1
1
Bladder Cancer
1
1
Bone Diseases
1
1
Brain Hypoxia
1
1
Brain Injury: Hippocampal Damage
1
1
Brain Injury: Traumatic
1
1
Cancers: Multi-Drug Resistant
1
1
Central Nervous System Diseases
1
1
Cholesterol: Oxidation
1
1
Degenerative Disk Disease
1
1
Demyelinating Diseases
1
1
Dental Caries
1
1
Dyslipidemias
1
1
Endothelial Damage
1
1
Enterovirus: Type 71
1
1
Fibrosarcoma
1
1
Fibrosis
1
1
Gastrointestinal Cancer
1
1
Glioblastoma Multiforme
1
1
Hepatitis A
1
1
Hepatitis B
1
1
Hepatitis C
1
1
Histamine: Elevated
1
1
Homocysteine: Elevated
1
1
Hyperhomocysteinemia
1
1
Immune Dysregulation: TH1 dominance
1
1
Immune Dysregulation: TH1/TH2 imbalance
1
1
Lead Poisoning
1
1
Leukemia: Chronic myelogenous leukemia (CML)
1
1
Leukemia: Multi-Drug Resistant
1
1
Liver Disease
1
1
Liver Steatosis
1
1
Medulloblastoma
1
1
Mitochondrial Dysfunction
1
1
Nasopharyngeal Cancer
1
1
Pesticide Toxicity
1
1
Prion Diseases
1
1
Prostatic Hyperplasia: Benign
1
1
Radiation-Induced Illness: Cesium-137 Exposure
1
1
Retinal Diseases
1
1
Retinoblastoma
1
1
Rhinovirus Infection
1
1
Scars: Hyperplastic
1
1
Sperm Quality: Low
1
1
Steptococcus Mutans Infections
1
1
Surgery: Anesthesiology
1
1
120 Pharmacological Actions Researched for Ginsenosides
Name
AC
CK
Focus
Neuroprotective Agents
105
194
Anti-Inflammatory Agents
91
174
Antioxidants
84
165
Antiproliferative
95
120
Apoptotic
98
112
Anti-Apoptotic
55
90
Tumor Necrosis Factor (TNF) Alpha Inhibitor
52
85
Cardioprotective
38
72
Hepatoprotective
32
56
NF-kappaB Inhibitor
34
56
Interleukin-6 Downregulation
28
53
Interleukin-1 beta downregulation
28
49
Chemotherapeutic
25
48
Anti-metastatic
31
43
Antineoplastic Agents
26
31
Immunomodulatory
20
30
Malondialdehyde Down-regulation
16
30
Vascular Endothelial Growth Factor Inhibitors
15
30
Cyclooxygenase 2 Inhibitors
18
29
Antidepressive Agents
14
27
Matrix metalloproteinase-2 (MMP-2) inhibitor
17
27
Cell cycle arrest
21
25
Chemoprotective Agents
15
25
Chemosensitizer
16
23
Matrix metalloproteinase-9 (MMP-9) inhibitor
11
22
Nrf2 activation
15
22
Hypoglycemic Agents
12
21
Anti-Angiogenic
7
19
Hypoxia inducible factor-1 alpha (HIF-1α) inhibitor
8
19
Renoprotective
7
19
Superoxide Dismutase Up-regulation
10
18
Chemopreventive
6
16
MicroRNA modulator
10
15
Angiogenesis Inhibitors
10
14
Bcl-2 protein down-regulation
12
14
Autophagy Up-regulation
9
13
Anti-Fibrotic
7
12
Anti-HIV Agents
2
11
Radioprotective
2
11
Brain-derived neurotrophic factor modulator
5
10
HIV Protease Inhibitors
1
10
Hypolipidemic
6
10
Tumor Suppressor Protein p53 Upregulation
7
8
Antiviral Agents
5
7
Chondroprotective
2
7
Matrix Metalloproteinase-13 (MMP-13) Inhibitor
3
7
Nitric Oxide Inhibitor
5
7
Photoprotective
6
7
Angiogenesis Inducing Agents
3
6
Cytoprotective
5
6
Matrix metalloproteinase-1 (MMP-1) inhibitor
2
6
Osteoprotective
4
6
Heme oxygenase-1 up-regulation
3
5
Histone deacetylase inhibitor
3
5
Interferon Gamma Reducer
3
5
Prophylactic Agents
3
5
Prostaglandin PGE2 downregulation
1
5
Anti-atherogenic
2
4
Antihypertensive Agents
2
4
Antinoceceptive
2
4
Autophagy Inhibitors
3
4
Enzyme Inhibitors
3
4
Neuritogenic
3
4
Pancreato Protective Agents
3
4
Radiosensitizer
3
4
Vasodilator Agents
2
4
Wnt/β-catenin signaling pathway modulation
3
4
Anticarcinogenic Agents
2
3
Heat Shock Protein Down-Regulation
2
3
Interleukin-4 downregulation
2
3
Transforming growth factor beta (TGF-β) inhibitor
2
3
Adiponectin upregulation
1
2
Analgesics
1
2
Anti-Adipogenic
1
2
Anti-Anxiety Agents
1
2
Anti-Bacterial Agents
1
2
Anti-Platelet
1
2
Anticholesteremic Agents
1
2
Antimicrobial
2
2
Antipruritics
1
2
Aphrodisiac
1
2
DNA Repair Up-regulation
2
2
E-cadherin down-regulation
1
2
Epidermal growth factor receptor (EGFR) inhibitor
1
2
Fertility Agents: Female
1
2
Gastroprotective
1
2
Heme oxygenase-1 inducer
2
2
Immunomodulatory: Th17 downregulation
1
2
Interleukin-10 downregulation
1
2
Interleukin-17 downregulation
1
2
Interleukin-18 down-regulation
1
2
Interleukin-8 downregulation
2
2
Multidrug Resistance Gene Modulators
1
2
Nitric Oxide Enhancer
1
2
Regenerative
1
2
SIRT1 Activator
1
2
Secretagogue
1
2
Telomerase Inhibitor
2
2
Vascular Endothelial Growth Factor A Inhibitor
1
2
Vascular Endothelial Growth Factor C Inhibitor
1
2
Vascular Endothelial Growth Factor Regulator
2
2
Viral Hemagglutinin Inhibitor
1
2
Acetylcholinesterase Down-Regulation
1
1
Anti-Retroviral Agents
1
1
Cyclin D1 Down-Regulation
1
1
Fertility Agents: Male
1
1
Glucagon Like peptide 1 (GLP-1) Up-regulation
1
1
Histamine down-regulation
1
1
Immunostimulatory
1
1
Insulin Sensitizers
1
1
Insulin-Like Growth Factor Enhancer/Upregulation
1
1
Interleukin-1 alpha downregulation
1
1
Interleukin-10 upregulation
1
1
Interleukin-12 downregulation
1
1
Interleukin-2 upregulation
1
1
Matrix Metalloproteinase-7 (MMP-7) Inhibitor
1
1
P21 Activation
1
1
Paraptosis
1
1
Survivin Down-Regulation
1
1
Vascular Endothelial Growth Factor A Enhancer
1
1
Research Articles
597
Cumulative Knowledge Score
965
Overall Research Rating
EXCELLENT
Related Topics
Ginsenosides is a Sub of the following Topic
Ginseng
View the Evidence:
812 Abstracts with Ginsenosides Research
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[+]
A meta-analysis of ginsenoside Rg3 combined with chemotherapy for digestive system cancer in China.
Dec 31, 2018
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Evid Based Complement Alternat Med. 2019 ;2019:2417418. Epub 2019 Dec 17. PMID:
31929811
Article Published Date
: Dec 31, 2018
Study Type
: Meta Analysis, Review
Additional Links
Substances
:
Ginsenosides
Diseases
:
Colorectal Cancer
,
Esophageal Cancer
,
Gastric Cancer
,
Liver Cancer
,
Pancreatic Cancer
Pharmacological Actions
:
Angiogenesis Inhibitors
,
Anti-metastatic
,
Antiproliferative
,
Chemotherapeutic
[+]
Available findings demonstrated the preclinical evidence that Ginsenoside-Rb1 has a potential neuroprotective effects.
Dec 31, 2019
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Front Pharmacol. 2020 ;11:285. Epub 2020 Mar 31. PMID:
32296332
Article Published Date
: Dec 31, 2019
Study Type
: Meta Analysis, Review
Additional Links
Substances
:
Ginsenosides
Diseases
:
Stroke: Ischemic
Pharmacological Actions
:
Anti-Apoptotic
,
Anti-Inflammatory Agents
,
Antioxidants
,
Neurogenesis
,
Neuroprotective Agents
[+]
Ginsenoside Rg3 for chemotherapy-induced myelosuppression.
Dec 31, 2019
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Front Pharmacol. 2020 ;11:649. Epub 2020 May 12. PMID:
32477128
Article Published Date
: Dec 31, 2019
Study Type
: Meta Analysis, Review
Additional Links
Substances
:
Ginsenosides
Diseases
:
Chemotherapy Induced Myelotoxicity
Pharmacological Actions
:
Chemoprotective Agents
,
Immunomodulatory
[+]
American ginseng has radioprotective effect on human lymphocytes at 90 minutes postirradiation.
May 01, 2010
Click here to read the entire abstract
Pubmed Data
: J Altern Complement Med. 2010 May;16(5):561-7. PMID:
20491513
Article Published Date
: May 01, 2010
Study Type
: Human Study
Additional Links
Substances
:
Ginseng (American)
,
Ginsenosides
Diseases
:
DNA damage
,
Oxidative Stress
,
Radiation Induced Illness
Pharmacological Actions
:
Antioxidants
,
Radioprotective
Additional Keywords
:
Plant Extracts
[+]
American ginseng reduces oxidative stress in patients taking the antiviral medication zidovudine without altering drug pharmacokinetics.
May 01, 2008
Click here to read the entire abstract
Pubmed Data
: J Clin Pharmacol. 2008 May;48(5):599-609. Epub 2008 Mar 4. PMID:
18319359
Article Published Date
: May 01, 2008
Study Type
: Human Study
Additional Links
Substances
:
Ginseng (American)
,
Ginsenosides
Diseases
:
HIV Infections
Pharmacological Actions
:
Anti-HIV Agents
,
Antioxidants
,
HIV Protease Inhibitors
Additional Keywords
:
Drug: Zidovudine
,
Plant Extracts
[+]
Daily supplementation of Korean Red Ginseng for 8 weeks significantly improved the TBUT score and subjective dry eye symptoms, as compared to placebo.
Dec 31, 2014
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: J Ginseng Res. 2015 Jan ;39(1):7-13. Epub 2014 Jul 23. PMID:
25535471
Article Published Date
: Dec 31, 2014
Study Type
: Human Study
Additional Links
Substances
:
Ginseng (Korean)
,
Ginsenosides
Diseases
:
Dry Eye Syndromes
Pharmacological Actions
:
Anti-Inflammatory Agents
Additional Keywords
:
Significant Treatment Outcome
,
Supplementation
[+]
Enzyme-treated red ginseng extract significantly improved eye wrinkle roughness, skin elasticity, and moisture content of skin.
Jun 30, 2016
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: J Ginseng Res. 2016 Jul ;40(3):260-8. Epub 2015 Aug 31. PMID:
27616902
Article Published Date
: Jun 30, 2016
Study Type
: Human Study
Additional Links
Substances
:
Ginseng (Korean)
,
Ginsenosides
Diseases
:
Aging Skin
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Antioxidants
[+]
Ginsenoside Rb1 treatment was effective in reducing the extent of oxidative stress and inflammation in chronic kidney disease patients.
Jan 31, 2017
Click here to read the entire abstract
Pubmed Data
: Inflammopharmacology. 2017 Feb ;25(1):33-40. Epub 2016 Nov 17. PMID:
27853891
Article Published Date
: Jan 31, 2017
Study Type
: Human Study
Additional Links
Substances
:
Ginsenosides
Diseases
:
Chronic Kidney Disease (CKD)
,
Oxidative Stress
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Antioxidants
,
Renoprotective
[+]
Ginsenoside Rd is efficacious against acute ischemic stroke.
Apr 30, 2016
Click here to read the entire abstract
Pubmed Data
: Mol Neurobiol. 2016 May ;53(4):2529-40. Epub 2015 Jun 17. PMID:
26081140
Article Published Date
: Apr 30, 2016
Study Type
: Human Study
Additional Links
Substances
:
Ginsenosides
Diseases
:
Stroke: Ischemic
Pharmacological Actions
:
Neuroprotective Agents
,
NF-kappaB Inhibitor
[+]
Ginsenoside Rg3 could be used as a new regimen to delay acquired resistance of epidermal growth factor receptor-tyrosine kinase inhibitors.
Oct 24, 2016
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Oncotarget. 2016 Oct 25 ;7(43):70535-70545. PMID:
27655708
Article Published Date
: Oct 24, 2016
Study Type
: Human Study
Additional Links
Substances
:
Ginsenosides
Diseases
:
Cancers: Drug Resistant
,
Carcinoma: Non-Small-Cell Lung
,
Lung Cancer
Pharmacological Actions
:
Chemotherapeutic
[+]
Ginsenoside Rg3 inhibits HIF-1α and VEGF expression in patients with acute leukemia.
Dec 31, 2013
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Int J Clin Exp Pathol. 2014 ;7(5):2172-8. Epub 2014 Apr 15. PMID:
24966925
Article Published Date
: Dec 31, 2013
Study Type
: Human Study
Additional Links
Substances
:
Ginsenosides
Diseases
:
Leukemia: Acute myelogenous leukemia (AML)
Pharmacological Actions
:
Anti-Angiogenic
,
Hypoxia inducible factor-1 alpha (HIF-1α) inhibitor
,
Vascular Endothelial Growth Factor Inhibitors
[+]
Ginsenoside-Rd improves outcome of acute ischaemic stroke.
May 31, 2012
Click here to read the entire abstract
Pubmed Data
: Eur J Neurol. 2012 Jun ;19(6):855-63. Epub 2012 Jan 10. PMID:
22233205
Article Published Date
: May 31, 2012
Study Type
: Human Study
Additional Links
Substances
:
Ginsenosides
Diseases
:
Stroke: Ischemic
Pharmacological Actions
:
Neuroprotective Agents
[+]
Ginsenoside-Rd may be of some benefit in acute ischaemic stroke.
Apr 30, 2009
Click here to read the entire abstract
Pubmed Data
: Eur J Neurol. 2009 May ;16(5):569-75. Epub 2009 Feb 19. PMID:
19236467
Article Published Date
: Apr 30, 2009
Study Type
: Human Study
Additional Links
Substances
:
Ginsenosides
Diseases
:
Brain Ischemia
,
Stroke
Pharmacological Actions
:
Neuroprotective Agents
[+]
High-dose ginsenoside supplementation augmented the improvement of aerobic capacity by exercise training.
Mar 31, 2018
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: J Ginseng Res. 2018 Apr ;42(2):192-198. Epub 2017 Apr 5. PMID:
29719466
Article Published Date
: Mar 31, 2018
Study Type
: Human Study
Additional Links
Substances
:
Ginsenosides
Diseases
:
Athletic Performance
Therapeutic Actions
:
Exercise
[+]
Protective effects of ginsenoside on myocardiac ischemic and reperfusion injuries.
Sep 30, 1994
Click here to read the entire abstract
Pubmed Data
: Zhonghua Yi Xue Za Zhi. 1994 Oct ;74(10):626-8, 648. PMID:
7842343
Article Published Date
: Sep 30, 1994
Study Type
: Human Study
Additional Links
Substances
:
Ginsenosides
Diseases
:
Myocardial Ischemia
Pharmacological Actions
:
Cardioprotective
[+]
The combination of transcatheter arterial chemoembolization and ginsenoside Rg3 may prolong overall survival when compared with it alone.
Jul 31, 2016
Click here to read the entire abstract
Article Publish Status
: This is a free article.
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Pubmed Data
: Radiology. 2016 Aug ;280(2):630-9. Epub 2016 Feb 17. PMID:
26885681
Article Published Date
: Jul 31, 2016
Study Type
: Human Study
Additional Links
Substances
:
Ginsenosides
Diseases
:
Liver Cancer
Pharmacological Actions
:
Chemotherapeutic
[+]
These results suggest a potential role for ginseng in modulating salivary androgen levels.
May 27, 2020
Click here to read the entire abstract
Article Publish Status
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Pubmed Data
: Nutrients. 2020 May 28 ;12(6). Epub 2020 May 28. PMID:
32481563
Article Published Date
: May 27, 2020
Study Type
: Human Study
Additional Links
Substances
:
Ginsenosides
Diseases
:
Testosterone: Too High
[+]
This data suggested that consumers on a Western diet should obtain better cancer prevention effects with American ginseng intake.
Mar 31, 2017
Click here to read the entire abstract
Pubmed Data
: Biomed Chromatogr. 2017 Apr ;31(4). Epub 2016 Oct 13. PMID:
27606833
Article Published Date
: Mar 31, 2017
Study Type
: Human Study
Additional Links
Substances
:
Ginseng (American)
,
Ginsenosides
Diseases
:
Cancers: All
Pharmacological Actions
:
Chemopreventive
[+]
Cytoprotective effects of ginsenoside Rd on apoptosis-associated cell death in the isolated human pancreatic islets.
Dec 31, 2018
Click here to read the entire abstract
Article Publish Status
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Pubmed Data
: EXCLI J. 2019 ;18:666-676. Epub 2019 Aug 22. PMID:
31611749
Article Published Date
: Dec 31, 2018
Study Type
: Human In Vitro
Additional Links
Substances
:
Ginsenosides
Diseases
:
Diabetes Mellitus: Type 1
Pharmacological Actions
:
Cytoprotective
,
Pancreato Protective Agents
[+]
Ginsenoside 20(S)-Rh2 has therapeutic potential for the treatment with colorectal cancer.
Dec 23, 2016
Click here to read the entire abstract
Pubmed Data
: J Ethnopharmacol. 2016 Dec 24 ;194:83-90. Epub 2016 Aug 23. PMID:
27566200
Article Published Date
: Dec 23, 2016
Study Type
: Human In Vitro
Additional Links
Substances
:
Ginseng
,
Ginsenosides
Diseases
:
Colorectal Cancer
Pharmacological Actions
:
Anti-metastatic
,
Chemosensitizer
,
Interleukin-6 Downregulation
,
Matrix metalloproteinase-1 (MMP-1) inhibitor
,
Matrix metalloproteinase-2 (MMP-2) inhibitor
,
Matrix metalloproteinase-9 (MMP-9) inhibitor
Additional Keywords
:
Chemotherapeutic Synergy: Doxorubicin
[+]
Ginsenoside Rb1 shows potential for use in skin care products to protect the skin against damage by fine particles.
Sep 08, 2019
Click here to read the entire abstract
Article Publish Status
: This is a free article.
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Pubmed Data
: Antioxidants (Basel). 2019 Sep 9 ;8(9). Epub 2019 Sep 9. PMID:
31505827
Article Published Date
: Sep 08, 2019
Study Type
: Human In Vitro
Additional Links
Substances
:
Ginsenosides
Diseases
:
Air Pollution Linked Toxicity
,
Oxidative Stress
Pharmacological Actions
:
Antioxidants
[+]
Ginsenoside Rg1 can inhibit inflammatory responses in human chondrocytes in vitro and reduce articular cartilage damage in vivo.
Mar 09, 2017
Click here to read the entire abstract
Article Publish Status
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Pubmed Data
: Nutrients. 2017 Mar 10 ;9(3). Epub 2017 Mar 10. PMID:
28287423
Article Published Date
: Mar 09, 2017
Study Type
: Animal Study, Human In Vitro
Additional Links
Substances
:
Ginsenosides
Diseases
:
Osteoarthritis
Pharmacological Actions
:
Chondroprotective
,
Cyclooxygenase 2 Inhibitors
,
Matrix Metalloproteinase-13 (MMP-13) Inhibitor
,
Prostaglandin PGE2 downregulation
[+]
Red ginseng extract promotes the hair growth in cultured human hair follicles.
Feb 28, 2015
Click here to read the entire abstract
Article Publish Status
: This is a free article.
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Pubmed Data
: J Med Food. 2015 Mar ;18(3):354-62. Epub 2014 Nov 14. PMID:
25396716
Article Published Date
: Feb 28, 2015
Study Type
: Human In Vitro
Additional Links
Substances
:
Ginseng (Korean)
,
Ginsenosides
Diseases
:
Hair Loss
Pharmacological Actions
:
Antiproliferative
Additional Keywords
:
Hair Regeneration
,
Plant Extracts
[+]
Ginsenoside Rb2 improves insulin resistance by inhibiting adipocyte pyroptosis.
Nov 30, 2020
Click here to read the entire abstract
Article Publish Status
: This is a free article.
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Pubmed Data
: Adipocyte. 2020 Dec ;9(1):302-312. PMID:
32580621
Article Published Date
: Nov 30, 2020
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Ginsenosides
Diseases
:
Insulin Resistance
,
Obesity
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Interleukin-1 beta downregulation
Additional Keywords
:
Anti-Obesity Agents
[+]
Ginsenoside Rk1 alleviates LPS-induced depression-like behavior in mice by promoting BDNF and suppressing the neuroinflammatory response.
Sep 30, 2020
Click here to read the entire abstract
Pubmed Data
: Biochem Biophys Res Commun. 2020 Oct 1 ;530(4):658-664. Epub 2020 Aug 5. PMID:
32768191
Article Published Date
: Sep 30, 2020
Study Type
: Animal Study
Additional Links
Substances
:
Ginsenosides
Diseases
:
Depression
,
Lipopolysaccharide-Induced Toxicity
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Antidepressive Agents
,
Brain-derived neurotrophic factor modulator
[+]
The dual roles of ginsenosides in improving the anti-tumor efficiency of cyclophosphamide in mammary carcinoma mice.
Aug 23, 2020
Click here to read the entire abstract
Pubmed Data
: J Ethnopharmacol. 2020 Aug 24:113271. Epub 2020 Aug 24. PMID:
32853742
Article Published Date
: Aug 23, 2020
Study Type
: Animal Study
Additional Links
Substances
:
Ginsenosides
Diseases
:
Breast Cancer
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Antioxidants
,
Chemotherapeutic
,
Nrf2 activation
Additional Keywords
:
Natural Substance/Drug Synergy
[+]
"Ginsenoside Rg1 promotes peripheral nerve regeneration in rat model of nerve crush injury."
Jul 04, 2010
Click here to read the entire abstract
Pubmed Data
: Neurosci Lett. 2010 Jul 5 ;478(2):66-71. Epub 2010 May 8. PMID:
20438804
Article Published Date
: Jul 04, 2010
Study Type
: Animal Study
Additional Links
Substances
:
Ginsenosides
Diseases
:
Nerve Injuries
Pharmacological Actions
:
Neuritogenic
,
Neuroprotective Agents
Additional Keywords
:
Nerve Regeneration
[+]
20 (R) -ginsenoside Rg3 entrapped in chitosan microspheres may have a beneficial effect against fatigue.
Jan 05, 2017
Click here to read the entire abstract
Pubmed Data
: Curr Drug Deliv. 2017 09 6 ;14(6):867-874. PMID:
27834150
Article Published Date
: Jan 05, 2017
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Ginsenosides
Diseases
:
Fatigue
[+]
20 (S)-ginsenoside Rg3 can inhibit the formation of gastric ulcer.
Sep 30, 2019
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: J Ginseng Res. 2019 Oct ;43(4):550-561. Epub 2018 Apr 9. PMID:
31695563
Article Published Date
: Sep 30, 2019
Study Type
: Animal Study
Additional Links
Substances
:
Ginsenosides
Diseases
:
Gastric Ulcer
Pharmacological Actions
:
Gastroprotective
[+]
20(R)-Ginsenoside Rg3 protects SH-SY5Y cells against apoptosis induced by oxygen and glucose deprivation/reperfusion.
Jan 14, 2017
Click here to read the entire abstract
Pubmed Data
: Bioorg Med Chem Lett. 2017 08 15 ;27(16):3867-3871. Epub 2017 Jun 19. PMID:
28709827
Article Published Date
: Jan 14, 2017
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Ginsenosides
Diseases
:
Cerebral Ischemia
Pharmacological Actions
:
Anti-Apoptotic
,
Neuroprotective Agents
[+]
20(S)-ginsenoside Rg(3) showed the significant protective effects on cyclophosphamide-induced cell DNA damage and apoptosis.
Jan 31, 2008
Click here to read the entire abstract
Pubmed Data
: Arch Toxicol. 2008 Feb ;82(2):117-23. Epub 2007 Jun 28. PMID:
17598087
Article Published Date
: Jan 31, 2008
Study Type
: Animal Study
Additional Links
Substances
:
Ginsenosides
Diseases
:
Chemotherapy-Induced Toxicity: Cyclophosphamide
,
Oxidative Stress
Pharmacological Actions
:
Anti-Apoptotic
,
Malondialdehyde Down-regulation
,
Superoxide Dismutase Up-regulation
[+]
20(S)-ginsenoside Rg3, a neuroprotective agent, inhibits mitochondrial permeability transition pores in rat brain.
Mar 31, 2009
Click here to read the entire abstract
Pubmed Data
: Phytother Res. 2009 Apr ;23(4):486-91. PMID:
19003949
Article Published Date
: Mar 31, 2009
Study Type
: Animal Study
Additional Links
Substances
:
Ginsenosides
Diseases
:
Cerebral Ischemia
Pharmacological Actions
:
Neuroprotective Agents
[+]
20(S)-ginsenoside-Rg3 reverses temozolomide resistance and restrains epithelial-mesenchymal transition progression in glioblastoma.
Dec 31, 2018
Click here to read the entire abstract
Article Publish Status
: This is a free article.
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Pubmed Data
: Cancer Sci. 2019 Jan ;110(1):389-400. Epub 2018 Dec 14. PMID:
30431207
Article Published Date
: Dec 31, 2018
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Ginsenosides
Diseases
:
Cancers: Drug Resistant
,
Glioblastoma
Pharmacological Actions
:
Anti-metastatic
,
Chemosensitizer
[+]
A cocktail of betulinic acid, parthenolide, honokiol and ginsenoside Rh2 in liposome systems for lung cancer treatment.
Dec 31, 2019
Click here to read the entire abstract
Article Publish Status
: This is a free article.
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Pubmed Data
: Nanomedicine (Lond). 2020 Jan ;15(1):41-54. PMID:
31868113
Article Published Date
: Dec 31, 2019
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Betulinic acid
,
Ginsenosides
,
Honokiol
,
Parthenolide
Diseases
:
Lung Cancer
Pharmacological Actions
:
Chemotherapeutic
Additional Keywords
:
Natural Substance Synergy
[+]
A Ginkgo biloba and ginsenoside Rg3 extract possesses significant protective activities against ADHD-like conditions.
Feb 28, 2014
Click here to read the entire abstract
Pubmed Data
: Food Chem Toxicol. 2014 Mar ;65:280-92. Epub 2014 Jan 3. PMID:
24394491
Article Published Date
: Feb 28, 2014
Study Type
: Animal Study
Additional Links
Substances
:
Ginsenosides
Diseases
:
Attention Deficit Disorder with Hyperactivity
Pharmacological Actions
:
Antioxidants
,
Cytoprotective
,
Neuroprotective Agents
Additional Keywords
:
Plant Extracts
[+]
A purified dry extract of ginseng may improve cancer related fatigue via regulation of inflammatory responses and hematopoiesis.
Dec 31, 2014
Click here to read the entire abstract
Article Publish Status
: This is a free article.
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Pubmed Data
: Evid Based Complement Alternat Med. 2015 ;2015:197459. Epub 2015 Apr 7. PMID:
25945105
Article Published Date
: Dec 31, 2014
Study Type
: Animal Study
Additional Links
Substances
:
Ginseng
,
Ginsenosides
Diseases
:
Chemotherapy-Induced Toxicity: 5-fluorouracil
,
Fatigue: Cancer-Associated
Pharmacological Actions
:
Chemoprotective Agents
,
Interleukin-6 Downregulation
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
Additive antiangiogenesis effect of ginsenoside Rg3 with low-dose metronomic temozolomide on rat glioma cells both in vivo and in vitro.
Feb 12, 2016
Click here to read the entire abstract
Article Publish Status
: This is a free article.
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Pubmed Data
: J Exp Clin Cancer Res. 2016 Feb 13 ;35:32. Epub 2016 Feb 13. PMID:
26872471
Article Published Date
: Feb 12, 2016
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Ginsenosides
Diseases
:
Glioblastoma
Pharmacological Actions
:
Anti-Angiogenic
,
Antiproliferative
,
Cell cycle arrest
Additional Keywords
:
Natural Substance/Drug Synergy
[+]
All of these experimental results suggested that Ginsenoside Rg3 may serve as a reliable drug for the treatment of patients with keloids.
Feb 28, 2018
Click here to read the entire abstract
Article Publish Status
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Pubmed Data
: Int J Mol Med. 2018 Mar ;41(3):1487-1499. Epub 2018 Jan 4. PMID:
29328420
Article Published Date
: Feb 28, 2018
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Ginsenosides
Diseases
:
Keloid
Pharmacological Actions
:
Antiproliferative
,
Transforming growth factor beta (TGF-β) inhibitor
[+]
Alleviation of diabetic complications by ginsenoside Rg3-enriched red ginseng extract in western diet-fed mice.
Jun 30, 2018
Click here to read the entire abstract
Article Publish Status
: This is a free article.
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Pubmed Data
: J Ginseng Res. 2018 Jul ;42(3):352-355. Epub 2017 Apr 24. PMID:
29983617
Article Published Date
: Jun 30, 2018
Study Type
: Animal Study
Additional Links
Substances
:
Ginseng (Korean)
,
Ginsenosides
Diseases
:
Cardiovascular Diseases
,
Diabetic Complications
Pharmacological Actions
:
Hypoglycemic Agents
,
Hypolipidemic
Additional Keywords
:
Plant Extracts
Anti Therapeutic Actions
:
Western Diet
[+]
Ameliorative effects of Compound K and ginsenoside Rh1 on non-alcoholic fatty liver disease in rats.
Jan 19, 2017
Click here to read the entire abstract
Article Publish Status
: This is a free article.
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Pubmed Data
: Sci Rep. 2017 Jan 20 ;7:41144. Epub 2017 Jan 20. PMID:
28106137
Article Published Date
: Jan 19, 2017
Study Type
: Animal Study
Additional Links
Substances
:
Ginsenosides
,
Panax Notoginseng
Diseases
:
Nonalcoholic fatty liver disease (NAFLD)
Pharmacological Actions
:
Hepatoprotective
Additional Keywords
:
Ginsenosides
,
Hepatoprotective
,
Nonalcoholic fatty liver disease (NAFLD)
,
Panax Notoginseng
[+]
Analgesic effect and related amino acids regulation of ginsenoside Rg3 in mouse pain models.
Dec 14, 2019
Click here to read the entire abstract
Pubmed Data
: Life Sci. 2019 Dec 15 ;239:117083. Epub 2019 Nov 20. PMID:
31759043
Article Published Date
: Dec 14, 2019
Study Type
: Animal Study
Additional Links
Substances
:
Ginsenosides
Diseases
:
Chronic Pain
Pharmacological Actions
:
Analgesics
,
Anti-Inflammatory Agents
[+]
Anti-ageing effect of red ginseng revealed.
Jun 30, 2018
Click here to read the entire abstract
Pubmed Data
: Phytochem Anal. 2018 Jul ;29(4):387-397. Epub 2018 Mar 24. PMID:
29573298
Article Published Date
: Jun 30, 2018
Study Type
: Animal Study
Additional Links
Substances
:
Ginseng
,
Ginsenosides
Diseases
:
Aging
Additional Keywords
:
Plant Extracts
[+]
Anti-hepatitic activity of ginsenoside Ro.
Nov 30, 1991
Click here to read the entire abstract
Pubmed Data
: Planta Med. 1991 Dec ;57(6):523-6. PMID:
1818342
Article Published Date
: Nov 30, 1991
Study Type
: Animal Study
Additional Links
Substances
:
Ginsenosides
Diseases
:
Chemically-Induced Liver Damage
Pharmacological Actions
:
Hepatoprotective
[+]
Anti-inflammatory effects of ginsenoside Rg1 and its metabolites ginsenoside Rh1 and 20(S)-protopanaxatriol.
Sep 04, 2015
Click here to read the entire abstract
Pubmed Data
: Eur J Pharmacol. 2015 Sep 5 ;762:333-43. Epub 2015 Jun 6. PMID:
26054809
Article Published Date
: Sep 04, 2015
Study Type
: Animal Study
Additional Links
Substances
:
Ginsenosides
Diseases
:
Colitis
,
Lipopolysaccharide-Induced Toxicity
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Interleukin-6 Downregulation
,
NF-kappaB Inhibitor
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
Anti-obesity effects of ginsenosides in high-fat diet-fed rats.
May 29, 2019
Click here to read the entire abstract
Pubmed Data
: Chin J Integr Med. 2019 May 30. Epub 2019 May 30. PMID:
31144161
Article Published Date
: May 29, 2019
Study Type
: Animal Study
Additional Links
Substances
:
Ginsenosides
Diseases
:
Obesity
Additional Keywords
:
Anti-Obesity Agents
[+]
Antidepressant effects of ginsenoside Rf on behavioral change in the glial degeneration model of depression by reversing glial loss.
Jun 30, 2020
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: J Ginseng Res. 2020 Jul ;44(4):603-610. Epub 2019 Aug 22. PMID:
32617040
Article Published Date
: Jun 30, 2020
Study Type
: Animal Study
Additional Links
Substances
:
Ginsenosides
Diseases
:
Depression
Pharmacological Actions
:
Antidepressive Agents
[+]
Antidepressant-like effect of altered Korean red ginseng in mice.
Mar 31, 2011
Click here to read the entire abstract
Pubmed Data
: Behav Med. 2011 Apr ;37(2):42-6. PMID:
21660771
Article Published Date
: Mar 31, 2011
Study Type
: Animal Study
Additional Links
Substances
:
Ginseng (Korean)
,
Ginsenosides
Diseases
:
Depression
Pharmacological Actions
:
Antidepressive Agents
Additional Keywords
:
Phytotherapy
,
Plant Extracts
Problem Substances
:
Fluoxetine (trade name Prozac)
[+]
Antidepressant-like effects of ginsenosides.
Dec 31, 2015
Click here to read the entire abstract
Pubmed Data
: Pharmacol Biochem Behav. 2016 Jan ;140:17-26. Epub 2015 Oct 31. PMID:
26528894
Article Published Date
: Dec 31, 2015
Study Type
: Animal Study
Additional Links
Substances
:
Ginsenosides
Diseases
:
Depression
Pharmacological Actions
:
Antidepressive Agents
[+]
Antiobesity effects of ginsenoside Rg1 on 3T3-L1 preadipocytes and high fat diet-induced obese mice mediated by AMPK.
Jun 26, 2018
Click here to read the entire abstract
Article Publish Status
: This is a free article.
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Pubmed Data
: Nutrients. 2018 Jun 27 ;10(7). Epub 2018 Jun 27. PMID:
29954059
Article Published Date
: Jun 26, 2018
Study Type
: Animal Study
Additional Links
Substances
:
Ginsenosides
Diseases
:
Obesity
Pharmacological Actions
:
Anti-Adipogenic
Additional Keywords
:
Anti-Obesity Agents
[+]
Antitumor activity of ginsenoside Rg3 in melanoma through downregulation of the ERK and Akt pathways.
May 31, 2019
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Int J Oncol. 2019 Jun ;54(6):2069-2079. Epub 2019 Apr 16. PMID:
31081060
Article Published Date
: May 31, 2019
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Ginsenosides
Diseases
:
Melanoma
Pharmacological Actions
:
Angiogenesis Inhibitors
,
Antiproliferative
,
Matrix metalloproteinase-2 (MMP-2) inhibitor
,
Matrix metalloproteinase-9 (MMP-9) inhibitor
,
Vascular Endothelial Growth Factor Inhibitors
[+]
Antitumor effect of ginsenoside Rg3 on gallbladder cancer.
Oct 31, 2018
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Oncol Lett. 2018 Nov ;16(5):5687-5696. Epub 2018 Aug 20. PMID:
30344724
Article Published Date
: Oct 31, 2018
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Ginsenosides
Diseases
:
Gallbladder Cancer
Pharmacological Actions
:
Antiproliferative
,
Apoptotic
[+]
Attenuating effect of Ginsenoside Rb1 on LPS-induced lung injury in rats.
Dec 31, 2013
Click here to read the entire abstract
Article Publish Status
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Pubmed Data
: J Inflamm (Lond). 2014 ;11(1):40. Epub 2014 Dec 5. PMID:
25530718
Article Published Date
: Dec 31, 2013
Study Type
: Animal Study
Additional Links
Substances
:
Ginsenosides
Diseases
:
Lipopolysaccharide-Induced Toxicity
,
Lung Injury: Acute
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
Black ginseng and ginsenoside Rb1 act as potential functional anti-obesity food agents.
Nov 11, 2019
Click here to read the entire abstract
Article Publish Status
: This is a free article.
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Pubmed Data
: Nutrients. 2019 Nov 12 ;11(11). Epub 2019 Nov 12. PMID:
31726767
Article Published Date
: Nov 11, 2019
Study Type
: Animal Study
Additional Links
Substances
:
Ginseng
,
Ginsenosides
Diseases
:
Obesity
Additional Keywords
:
Anti-Obesity Agents
[+]
Black ginseng extract counteracts streptozotocin-induced diabetes.
Dec 31, 2015
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: PLoS One. 2016 ;11(1):e0146843. Epub 2016 Jan 11. PMID:
26751692
Article Published Date
: Dec 31, 2015
Study Type
: Animal Study
Additional Links
Substances
:
Ginseng
,
Ginsenosides
Diseases
:
Diabetes Mellitus: Type 1
,
Diabetes Mellitus: Type 2
,
Hyperglycemia
Pharmacological Actions
:
Anti-Apoptotic
,
Hypoglycemic Agents
Additional Keywords
:
Plant Extracts
[+]
Black ginseng has ameliorative effects against acetaminophen induced hepatotoxicity.
Apr 20, 2017
Click here to read the entire abstract
Article Publish Status
: This is a free article.
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Pubmed Data
: Molecules. 2017 Apr 21 ;22(4). Epub 2017 Apr 21. PMID:
28430162
Article Published Date
: Apr 20, 2017
Study Type
: Animal Study
Additional Links
Substances
:
Ginsenosides
,
Panax Ginseng
Diseases
:
Acetaminophen (Tylenol) Toxicity
,
Oxidative Stress
Pharmacological Actions
:
Anti-Apoptotic
,
Anti-Inflammatory Agents
,
Antioxidants
,
Hepatoprotective
Additional Keywords
:
Phytotherapy
Problem Substances
:
Acetaminophen
,
Paracetamol
[+]
Both ginseng saponins, 20(R)- and 20(S)-ginsenoside-Rg3, possess an ability to inhibit the lung metastasis of tumor cells.
Aug 31, 1995
Click here to read the entire abstract
Pubmed Data
: Biol Pharm Bull. 1995 Sep ;18(9):1197-202. PMID:
8845804
Article Published Date
: Aug 31, 1995
Study Type
: Animal Study
Additional Links
Substances
:
Ginsenosides
Diseases
:
Lung Cancer
,
Melanoma
Pharmacological Actions
:
Anti-metastatic
,
Antineoplastic Agents
[+]
Cardioprotective effects of 20(S)-ginsenoside Rh2 against doxorubicin-induced cardiotoxicity.
Dec 31, 2011
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Evid Based Complement Alternat Med. 2012 ;2012:506214. Epub 2012 Oct 17. PMID:
23125868
Article Published Date
: Dec 31, 2011
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Ginsenosides
Diseases
:
Chemotherapy-Induced Toxicity: Doxorubicin
Pharmacological Actions
:
Cardioprotective
,
Chemoprotective Agents
[+]
Cellular and molecular mechanisms underlying the action of ginsenoside Rg1 against Alzheimer's disease.
Dec 24, 2012
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Neural Regen Res. 2012 Dec 25 ;7(36):2860-6. PMID:
25317137
Article Published Date
: Dec 24, 2012
Study Type
: Animal Study
Additional Links
Substances
:
Ginsenosides
Diseases
:
Alzheimer's Disease
Pharmacological Actions
:
Neuroprotective Agents
[+]
Certain ginsenosides inhibit lung inflammatory responses.
Sep 30, 2018
Click here to read the entire abstract
Pubmed Data
: J Ginseng Res. 2018 Oct ;42(4):476-484. Epub 2017 Jun 8. PMID:
30337808
Article Published Date
: Sep 30, 2018
Study Type
: Animal Study
Additional Links
Substances
:
Ginseng (Korean)
,
Ginsenosides
Diseases
:
Inflammation
Pharmacological Actions
:
Anti-Inflammatory Agents
[+]
Combination of the ginsenosides Rb3 and Rb2 exerts protective effects against myocardial ischemia reperfusion injury.
Nov 28, 2019
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Int J Mol Med. 2019 Nov 29. Epub 2019 Nov 29. PMID:
31789417
Article Published Date
: Nov 28, 2019
Study Type
: Animal Study
Additional Links
Substances
:
Ginsenosides
Diseases
:
Myocardial Ischemia
Pharmacological Actions
:
Cardioprotective
[+]
Combined ginsenoside Rg3 and transarterial embolization treatment limited metastasis and promoted survival.
Dec 31, 2013
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Onco Targets Ther. 2014 ;7:1945-54. Epub 2014 Oct 21. PMID:
25364265
Article Published Date
: Dec 31, 2013
Study Type
: Animal Study
Additional Links
Substances
:
Ginsenosides
Diseases
:
Liver Cancer
Pharmacological Actions
:
Anti-metastatic
[+]
Combining Rp1 with chemotherapeutic agents could circumvent drug resistance and improve treatment efficacy.
Mar 04, 2020
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Cancers (Basel). 2020 Mar 5 ;12(3). Epub 2020 Mar 5. PMID:
32151067
Article Published Date
: Mar 04, 2020
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Ginsenosides
Diseases
:
Colon Cancer
,
Lung Cancer
,
Ovarian Cancer
Pharmacological Actions
:
Apoptotic
,
Chemotherapeutic
[+]
Components of Astragalus and Panax notoginseng could strengthen the protective effects on cerebral ischemia injury.
Dec 31, 2014
Click here to read the entire abstract
Pubmed Data
: Am J Chin Med. 2015 ;43(7):1419-38. Epub 2015 Oct 18. PMID:
26477799
Article Published Date
: Dec 31, 2014
Study Type
: Animal Study
Additional Links
Substances
:
Astragalus
,
Ginsenosides
,
Panax Notoginseng
Diseases
:
Brain Ischemia
,
Inflammation
Pharmacological Actions
:
Anti-Apoptotic
,
Anti-Inflammatory Agents
,
Interleukin-1 beta downregulation
,
Neuroprotective Agents
,
NF-kappaB Inhibitor
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
Additional Keywords
:
Phytotherapy
[+]
Compound K protects pancreatic islet cells against apoptosis
Jun 26, 2014
Click here to read the entire abstract
Pubmed Data
: Life Sci. 2014 Jun 27 ;107(1-2):42-9. Epub 2014 May 5. PMID:
24802125
Article Published Date
: Jun 26, 2014
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Ginsenosides
Diseases
:
Diabetes Mellitus: Type 2
Pharmacological Actions
:
Anti-Apoptotic
,
Pancreato Protective Agents
[+]
Cultured wild ginseng root extract fermented by P. pentosaceus contains the distinctive ginsenosides Rg5/Rk1, which may ameliorate memory impairment.
May 19, 2019
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Nutrients. 2019 May 20 ;11(5). Epub 2019 May 20. PMID:
31137483
Article Published Date
: May 19, 2019
Study Type
: Animal Study
Additional Links
Substances
:
Ginsenosides
Diseases
:
Memory Disorders: Drug-Induced
Pharmacological Actions
:
Neuroprotective Agents
[+]
Diol-ginsenosides from Korean Red Ginseng delay the development of type 1 diabetes in diabetes-prone biobreeding rats.
Jun 30, 2020
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: J Ginseng Res. 2020 Jul ;44(4):619-626. Epub 2019 Jun 12. PMID:
32617042
Article Published Date
: Jun 30, 2020
Study Type
: Animal Study
Additional Links
Substances
:
Ginsenosides
Diseases
:
Diabetes Mellitus: Type 1: Prevention
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Interleukin-1 beta downregulation
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
Additional Keywords
:
Risk Reduction
[+]
Effect of ginsenoside pre-treatment on 5-hydroxytryptamine system in rats with myocardial infarction and depression.
Aug 31, 2016
Click here to read the entire abstract
Pubmed Data
: Zhonghua Nei Ke Za Zhi. 2016 Sep 1 ;55(9):700-4. PMID:
27586978
Article Published Date
: Aug 31, 2016
Study Type
: Animal Study
Additional Links
Substances
:
Ginsenosides
Diseases
:
Depression
,
Myocardial Infarction
[+]
Effects of ginseng saponins isolated from Red Ginseng roots on burn wound healing in mice.
Jun 30, 2006
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Br J Pharmacol. 2006 Jul ;148(6):860-70. Epub 2006 Jun 12. PMID:
16770323
Article Published Date
: Jun 30, 2006
Study Type
: Animal Study
Additional Links
Substances
:
Ginsenosides
Diseases
:
Wound Healing
[+]
Effects of ginsenoside Rg1 on glucose metabolism and liver injury in streptozotocin-induced type 2 diabetic rats.
Mar 29, 2017
Click here to read the entire abstract
Pubmed Data
: Genet Mol Res. 2017 Mar 30 ;16(1). Epub 2017 Mar 30. PMID:
28362999
Article Published Date
: Mar 29, 2017
Study Type
: Animal Study
Additional Links
Substances
:
Ginsenosides
Diseases
:
Diabetes Mellitus: Type 2
Pharmacological Actions
:
Anti-Apoptotic
,
Hepatoprotective
,
Hypoglycemic Agents
,
Hypolipidemic
[+]
EGFR signaling-dependent inhibition of glioblastoma growth by ginsenoside Rh2.
May 31, 2014
Click here to read the entire abstract
Pubmed Data
: Tumour Biol. 2014 Jun ;35(6):5593-8. Epub 2014 Feb 21. PMID:
24557544
Article Published Date
: May 31, 2014
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Ginsenosides
Diseases
:
Glioblastoma
Pharmacological Actions
:
Antiproliferative
,
Apoptotic
,
Epidermal growth factor receptor (EGFR) inhibitor
[+]
Endostar combined with ginsenoside Rg3 has stronger inhibiting effect on breast cancer tumor growth in tumor-bearing mice than single drug.
Jan 31, 2016
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Asian Pac J Trop Med. 2016 Feb ;9(2):180-3. Epub 2016 Jan 11. PMID:
26919952
Article Published Date
: Jan 31, 2016
Study Type
: Animal Study
Additional Links
Substances
:
Ginsenosides
Diseases
:
Breast Cancer
Pharmacological Actions
:
Anti-metastatic
,
Matrix metalloproteinase-2 (MMP-2) inhibitor
,
Matrix metalloproteinase-9 (MMP-9) inhibitor
,
Vascular Endothelial Growth Factor A Inhibitor
,
Vascular Endothelial Growth Factor C Inhibitor
,
Vascular Endothelial Growth Factor Inhibitors
Additional Keywords
:
Natural Substance/Drug Synergy
[+]
Evaluation of chemopreventive action of Ginsenoside Rp1.
Dec 31, 2005
Click here to read the entire abstract
Pubmed Data
: Biofactors. 2006 ;26(1):29-43. PMID:
16614481
Article Published Date
: Dec 31, 2005
Study Type
: Animal Study
Additional Links
Substances
:
Ginsenosides
Diseases
:
Lipid Peroxidation
,
Skin Cancer
Pharmacological Actions
:
Anticarcinogenic Agents
,
Chemopreventive
,
Superoxide Dismutase Up-regulation
[+]
Explosively puffed ginseng ameliorates ionizing radiation-induced injury of colon.
Apr 30, 2019
Click here to read the entire abstract
Pubmed Data
: J Med Food. 2019 May ;22(5):490-498. PMID:
31084541
Article Published Date
: Apr 30, 2019
Study Type
: Animal Study
Additional Links
Substances
:
Ginsenosides
Pharmacological Actions
:
Antioxidants
,
Radioprotective
Anti Therapeutic Actions
:
Low Dose Ionizing Radiation
[+]
Fermented black ginseng has beneficial effects on wound healing.
Sep 30, 2018
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: J Ginseng Res. 2018 Oct ;42(4):524-531. Epub 2017 Jul 25. PMID:
30337813
Article Published Date
: Sep 30, 2018
Study Type
: Animal Study
Additional Links
Substances
:
Fermented Foods and Beverages
,
Ginseng
,
Ginsenosides
Diseases
:
Wound Healing
[+]
Fermented red ginseng and ginsenoside Rd alleviate ovalbumin-induced allergic rhinitis.
Sep 30, 2019
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: J Ginseng Res. 2019 Oct ;43(4):635-644. Epub 2019 Mar 7. PMID:
31695569
Article Published Date
: Sep 30, 2019
Study Type
: Animal Study
Additional Links
Substances
:
Ginseng (Korean)
,
Ginsenosides
Diseases
:
Allergic Rhinitis
Pharmacological Actions
:
interleukin-13 down-regulation
,
Interleukin-4 downregulation
,
Interleukin-5 downregulation
[+]
findings provide strong evidence that ginsenoside-Rg1 can protect the liver against exhaustive exercise-induced oxidative damage.
Dec 31, 2011
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Evid Based Complement Alternat Med. 2012 ;2012:932165. Epub 2011 Sep 20. PMID:
21941591
Article Published Date
: Dec 31, 2011
Study Type
: Animal Study
Additional Links
Substances
:
Ginsenosides
Diseases
:
Exercise-Induced Tissue Damage
,
Oxidative Stress
Pharmacological Actions
:
Antioxidants
,
Hepatoprotective
[+]
Flavored black ginseng exhibited antitumor activity via improving immune function and inducing apoptosis.
May 23, 2017
Click here to read the entire abstract
Pubmed Data
: Food Funct. 2017 May 24 ;8(5):1880-1889. PMID:
28426048
Article Published Date
: May 23, 2017
Study Type
: Animal Study
Additional Links
Substances
:
Ginsenosides
Diseases
:
Cancers: All
Pharmacological Actions
:
Antineoplastic Agents
,
Apoptotic
,
Immunomodulatory
Additional Keywords
:
Plant Extracts
[+]
Ginkgo biloba extract improves brain uptake of ginsenosides by increasing blood-brain barrier permeability.
Jan 09, 2020
Click here to read the entire abstract
Pubmed Data
: J Ethnopharmacol. 2020 Jan 10 ;246:112243. Epub 2019 Sep 18. PMID:
31541722
Article Published Date
: Jan 09, 2020
Study Type
: Animal Study
Additional Links
Substances
:
Ginkgo biloba
,
Ginsenosides
Pharmacological Actions
:
Neuroprotective Agents
Additional Keywords
:
Blood Brain Barrier
[+]
Ginseng oligopeptides could be a novel natural agent for relieving exercise fatigue.
Dec 12, 2016
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Nutrients. 2016 Dec 13 ;8(12). Epub 2016 Dec 13. PMID:
27983571
Article Published Date
: Dec 12, 2016
Study Type
: Animal Study
Additional Links
Substances
:
Ginsenosides
,
Panax Ginseng
Diseases
:
Fatigue: Excercise-Induced
Pharmacological Actions
:
Antioxidants
Additional Keywords
:
Antioxidants
,
Fatigue: Excercise-Induced
,
Ginsenosides
,
Panax Ginseng
,
Polysaccharides
[+]
Ginseng reduces neurologic damage in subarachanoid hemorrhage.
Mar 31, 2010
Click here to read the entire abstract
Pubmed Data
: Curr Neurovasc Res. 2010 Mar 31. Epub 2010 Mar 31. PMID:
20353383
Article Published Date
: Mar 31, 2010
Study Type
: Animal Study
Additional Links
Substances
:
Ginsenosides
Diseases
:
Cerebral Aneurysm
,
Stroke
,
Subarachnoid hemorrhage
[+]
Ginsenoside 20(S)-protopanaxadiol attenuates depressive-like behaviour and neuroinflammation in chronic unpredictable mild stress.
May 24, 2020
Click here to read the entire abstract
Pubmed Data
: Behav Brain Res. 2020 May 25:112710. Epub 2020 May 25. PMID:
32464121
Article Published Date
: May 24, 2020
Study Type
: Animal Study
Additional Links
Substances
:
Ginsenosides
Diseases
:
Brain Inflammation
,
Depression
Pharmacological Actions
:
Anti-Apoptotic
,
Anti-Inflammatory Agents
,
Antidepressive Agents
[+]
Ginsenoside 20(S)-Rg3 inhibited the Warburg effect in ovarian cancer cells via H19/miR-324-5p/PKM2 pathway.
Dec 31, 2017
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Cell Physiol Biochem. 2018 ;51(3):1340-1353. Epub 2018 Nov 27. PMID:
30481782
Article Published Date
: Dec 31, 2017
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Ginsenosides
Diseases
:
Ovarian Cancer
Pharmacological Actions
:
Antiproliferative
,
MicroRNA modulator
Additional Keywords
:
Warburg Effect
[+]
Ginsenoside 20(S)-Rg3 upregulates FDFT1 via reducing miR-4425 to inhibit ovarian cancer progression.
Aug 29, 2020
Click here to read the entire abstract
Pubmed Data
: Arch Biochem Biophys. 2020 Aug 30:108569. Epub 2020 Aug 30. PMID:
32877662
Article Published Date
: Aug 29, 2020
Study Type
: Animal Study
Additional Links
Substances
:
Ginsenosides
Diseases
:
Ovarian Cancer
Pharmacological Actions
:
Anti-metastatic
,
Antiproliferative
,
MicroRNA modulator
[+]
Ginsenoside 20(s)-Rh2 as potent natural histone deacetylase inhibitors suppressing the growth of human leukemia cells.
Dec 04, 2015
Click here to read the entire abstract
Pubmed Data
: Chem Biol Interact. 2015 Dec 5 ;242:227-34. Epub 2015 Oct 19. PMID:
26482938
Article Published Date
: Dec 04, 2015
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Ginsenosides
Diseases
:
Leukemia
Pharmacological Actions
:
Antineoplastic Agents
,
Antiproliferative
,
Apoptotic
,
Cell cycle arrest
,
Histone deacetylase inhibitor
[+]
Ginsenoside 20(S)-Rh2 enhanced the antibacterial effects of ciprofloxacin in vitro and in vivo.
Oct 04, 2014
Click here to read the entire abstract
Pubmed Data
: Eur J Pharmacol. 2014 Oct 5 ;740:277-84. Epub 2014 Jul 20. PMID:
25054686
Article Published Date
: Oct 04, 2014
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Ginsenosides
Diseases
:
Staphylococcus aureus infection
Pharmacological Actions
:
Anti-Bacterial Agents
Additional Keywords
:
Natural Substance/Drug Synergy
[+]
Ginsenoside 25-OCH3-PPD could be used to curve the development of hepatic fibrosis.
Jul 10, 2018
Click here to read the entire abstract
Pubmed Data
: J Agric Food Chem. 2018 Jul 11 ;66(27):7023-7035. Epub 2018 Jul 2. PMID:
29929367
Article Published Date
: Jul 10, 2018
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Ginsenosides
Diseases
:
Liver Cirrhosis
,
Liver Fibrosis
Pharmacological Actions
:
Anti-Apoptotic
,
Anti-Fibrotic
,
Hepatoprotective
[+]
Ginsenoside ameliorated diabetic cognitive decline.
Jun 09, 2018
Click here to read the entire abstract
Pubmed Data
: Med Sci Monit. 2018 Jun 10 ;24:3922-3928. Epub 2018 Jun 10. PMID:
29886506
Article Published Date
: Jun 09, 2018
Study Type
: Animal Study
Additional Links
Substances
:
Ginsenosides
Diseases
:
Diabetes: Cognitive Dysfunction
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Interleukin-1 beta downregulation
,
Interleukin-6 Downregulation
,
Neuroprotective Agents
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
Ginsenoside CK may be a novel therapeutic potential for the treatment of neuroblastoma.
Aug 31, 2019
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Int J Mol Sci. 2019 Sep 1 ;20(17). Epub 2019 Sep 1. PMID:
31480534
Article Published Date
: Aug 31, 2019
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Ginsenosides
Diseases
:
Neuroblastoma
Pharmacological Actions
:
Apoptotic
,
Autophagy Inhibitors
[+]
Ginsenoside compound K ameliorates Alzheimer's disease in HT22 cells by adjusting energy metabolism.
Jul 29, 2019
Click here to read the entire abstract
Pubmed Data
: Mol Biol Rep. 2019 Jul 30. Epub 2019 Jul 30. PMID:
31364016
Article Published Date
: Jul 29, 2019
Study Type
: Animal Study
Additional Links
Substances
:
Ginsenosides
Diseases
:
Alzheimer's Disease
Pharmacological Actions
:
Anti-Apoptotic
,
Neuroprotective Agents
[+]
Ginsenoside compound K attenuates cognitive deficits in vascular dementia.
Feb 28, 2019
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: J Pharmacol Sci. 2019 Mar ;139(3):223-230. Epub 2019 Feb 13. PMID:
30799178
Article Published Date
: Feb 28, 2019
Study Type
: Animal Study
Additional Links
Substances
:
Ginsenosides
Diseases
:
Alzheimer's Disease
,
Cognitive Decline/Dysfunction
,
Dementia
Pharmacological Actions
:
Neuroprotective Agents
[+]
Ginsenoside compound K attenuates the development of atherosclerosis.
Jul 07, 2016
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Int J Mol Sci. 2016 Jul 8 ;17(7). Epub 2016 Jul 8. PMID:
27399689
Article Published Date
: Jul 07, 2016
Study Type
: Animal Study
Additional Links
Substances
:
Ginsenosides
Diseases
:
Atherosclerosis
,
Fatty Liver
Pharmacological Actions
:
Anti-atherogenic
,
Anti-Inflammatory Agents
[+]
Ginsenoside compound K might be a potential therapeutic candidate for human liver cancer.
Jun 18, 2018
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Molecules. 2018 Jun 19 ;23(6). Epub 2018 Jun 19. PMID:
29921768
Article Published Date
: Jun 18, 2018
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Ginsenosides
Diseases
:
Liver Cancer
Pharmacological Actions
:
Apoptotic
,
STAT3 Inhibitor
[+]
Ginsenoside compound-K inhibits the activity of B cells through inducing IgD-B cell receptor endocytosis in mice with collagen-induced arthritis.
Jun 03, 2019
Click here to read the entire abstract
Pubmed Data
: Inflammopharmacology. 2019 Jun 4. Epub 2019 Jun 4. PMID:
31165333
Article Published Date
: Jun 03, 2019
Study Type
: Animal Study
Additional Links
Substances
:
Ginsenosides
Diseases
:
Arthritis
Pharmacological Actions
:
Immunomodulatory
[+]
Ginsenoside F2 may be a novel therapeutic approach for treating skin inflammation.
Sep 29, 2016
Click here to read the entire abstract
Pubmed Data
: Biochem Biophys Res Commun. 2016 Sep 30 ;478(4):1713-9. Epub 2016 Sep 3. PMID:
27596969
Article Published Date
: Sep 29, 2016
Study Type
: Animal Study
Additional Links
Substances
:
Ginsenosides
Diseases
:
Dermatitis
,
Inflammation
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Antioxidants
,
Interleukin-17 downregulation
[+]
Ginsenoside F2 reduces hair loss by controlling apoptosis.
Dec 31, 2013
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Biol Pharm Bull. 2014 ;37(5):755-63. PMID:
24789999
Article Published Date
: Dec 31, 2013
Study Type
: Animal Study
Additional Links
Substances
:
Ginsenosides
Diseases
:
Hair Loss
Pharmacological Actions
:
Anti-Apoptotic
[+]
Ginsenoside GRb1 could reduce the cell apoptosis induced by spinal cord ischemia-reperfusion through inhibiting oxidative stress.
Aug 13, 2019
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: J Orthop Surg Res. 2019 Aug 14 ;14(1):259. Epub 2019 Aug 14. PMID:
31412899
Article Published Date
: Aug 13, 2019
Study Type
: Animal Study
Additional Links
Substances
:
Ginsenosides
Diseases
:
Ischemia
,
Spinal Cord Injuries
Pharmacological Actions
:
Antioxidants
[+]
Ginsenoside has an anti-neuroinflammation effect in a rat model of Alzheimer disease.
Jan 03, 2011
Click here to read the entire abstract
Pubmed Data
: Neurosci Lett. 2011 Jan 3;487(1):70-2. Epub 2010 Oct 7. PMID:
20933058
Article Published Date
: Jan 03, 2011
Study Type
: Animal Study
Additional Links
Substances
:
Ginsenosides
Diseases
:
Alzheimer's Disease
,
Brain Inflammation
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Neuroprotective Agents
[+]
Ginsenoside holds a promising potential as a pharmaceutical excipient in the pharmaceutical industries to increase the utility of various bioactives.
Jun 30, 2017
Click here to read the entire abstract
Pubmed Data
: Arch Pharm Res. 2017 Jul ;40(7):864-874. Epub 2017 Jul 15. PMID:
28712035
Article Published Date
: Jun 30, 2017
Study Type
: Animal Study
Additional Links
Substances
:
Curcumin
,
Ginsenosides
Additional Keywords
:
Increased Bioavailability
[+]
Ginsenoside metabolite compound K exerts anti-inflammatory and analgesic effects via downregulating COX2.
Jan 31, 2019
Click here to read the entire abstract
Pubmed Data
: Inflammopharmacology. 2019 Feb ;27(1):157-166. Epub 2018 Jun 26. PMID:
29946770
Article Published Date
: Jan 31, 2019
Study Type
: Animal Study
Additional Links
Substances
:
Ginsenosides
Diseases
:
Inflammation
Pharmacological Actions
:
Analgesics
,
Anti-Inflammatory Agents
,
Cyclooxygenase 2 Inhibitors
,
Postaglandin PGE2 downregulation
[+]
Ginsenoside protects against AKI via activation of HIF 1α and VEGF A in the kidney brain axis.
Jan 14, 2020
Click here to read the entire abstract
Pubmed Data
: Int J Mol Med. 2020 Jan 15. Epub 2020 Jan 15. PMID:
31985021
Article Published Date
: Jan 14, 2020
Study Type
: Animal Study
Additional Links
Substances
:
Ginsenosides
Diseases
:
Chronic Kidney Disease (CKD)
,
Kidney Damage
Pharmacological Actions
:
Antioxidants
,
Renoprotective
[+]
Ginsenoside Rb1 administration attenuates focal cerebral ischemic reperfusion injury.
Sep 30, 2018
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Exp Ther Med. 2018 Oct ;16(4):3020-3026. Epub 2018 Jul 26. PMID:
30214520
Article Published Date
: Sep 30, 2018
Study Type
: Animal Study
Additional Links
Substances
:
Ginsenosides
Diseases
:
Cerebral Ischemia
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Interleukin-6 Downregulation
,
Neuroprotective Agents
,
Nitric Oxide Inhibitor
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
Ginsenoside Rb1 alleviated high fat diet-induced apoptosis of hepatocytes of mice via PPAR-γ.
Dec 31, 2019
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Biomed Res Int. 2020 ;2020:2315230. Epub 2020 Jul 13. PMID:
32733933
Article Published Date
: Dec 31, 2019
Study Type
: Animal Study
Additional Links
Substances
:
Ginsenosides
Diseases
:
High Fat Diet
,
Nonalcoholic fatty liver disease (NAFLD)
Pharmacological Actions
:
Hepatoprotective
[+]
Ginsenoside Rb1 alleviates ox-LDL-induced vascular endothelium senescence via the SIRT1/Beclin-1/autophagy axis.
Oct 24, 2019
Click here to read the entire abstract
Pubmed Data
: J Cardiovasc Pharmacol. 2019 Oct 25. Epub 2019 Oct 25. PMID:
31658172
Article Published Date
: Oct 24, 2019
Study Type
: Animal Study
Additional Links
Substances
:
Ginsenosides
Diseases
:
Hyperlipidemia
,
Lipid Peroxidation
Pharmacological Actions
:
Antioxidants
,
SIRT1 Activator
[+]
Ginsenoside Rb1 ameliorates autophagy of hypoxia cardiomyocytes.
Jul 17, 2018
Click here to read the entire abstract
Pubmed Data
: Chin J Integr Med. 2018 Jul 18. Epub 2018 Jul 18. PMID:
30088211
Article Published Date
: Jul 17, 2018
Study Type
: Animal Study
Additional Links
Substances
:
Ginsenosides
Diseases
:
Hypoxia
Pharmacological Actions
:
Cardioprotective
[+]
Ginsenoside Rb1 ameliorates cisplatin-induced learning and memory impairments.
Sep 30, 2019
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: J Ginseng Res. 2019 Oct ;43(4):499-507. Epub 2017 Jul 25. PMID:
31695559
Article Published Date
: Sep 30, 2019
Study Type
: Animal Study
Additional Links
Substances
:
Ginsenosides
Diseases
:
Brain Inflammation
,
Chemotherapy-Induced Toxicity: Cisplatin
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Chemoprotective Agents
,
Neuroprotective Agents
[+]
Ginsenoside Rb1 ameliorates Staphylococcus aureus induced lung injury.
May 02, 2019
Click here to read the entire abstract
Pubmed Data
: Microb Pathog. 2019 May 3. Epub 2019 May 3. PMID:
31059756
Article Published Date
: May 02, 2019
Study Type
: Animal Study
Additional Links
Substances
:
Ginsenosides
Diseases
:
Lung Injury: Acute
,
Staphylococcus aureus infection
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Interleukin-1 beta downregulation
,
Interleukin-6 Downregulation
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
Ginsenoside Rb1 and baicalin might promote the proliferation and differentiation of endogenous neural stem cells.
Oct 12, 2017
Click here to read the entire abstract
Pubmed Data
: Brain Res. 2017 Oct 13. Epub 2017 Oct 13. PMID:
29038007
Article Published Date
: Oct 12, 2017
Study Type
: Animal Study
Additional Links
Substances
:
Baicalein
,
Ginsenosides
Diseases
:
Alzheimer's Disease
Pharmacological Actions
:
Neuroprotective Agents
[+]
Ginsenoside rb1 and rg3 attenuate glucocorticoid-induced neurotoxicity.
Jul 31, 2010
Click here to read the entire abstract
Pubmed Data
: Cell Mol Neurobiol. 2010 Aug ;30(6):857-62. Epub 2010 Mar 25. PMID:
20336484
Article Published Date
: Jul 31, 2010
Study Type
: Animal Study
Additional Links
Substances
:
Ginsenosides
Diseases
:
Anxiety
Pharmacological Actions
:
Anti-Apoptotic
,
Neuroprotective Agents
Problem Substances
:
Dexamethasone
[+]
Ginsenoside Rb1 attenuates angiotensin II-induced abdominal aortic aneurysm.
Sep 30, 2015
Click here to read the entire abstract
Pubmed Data
: Vascul Pharmacol. 2015 Oct ;73:86-95. Epub 2015 Apr 22. PMID:
25912763
Article Published Date
: Sep 30, 2015
Study Type
: Animal Study
Additional Links
Substances
:
Ginsenosides
Diseases
:
Aneurysm: Aortic
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Apoptotic
,
Matrix metalloproteinase-2 (MMP-2) inhibitor
[+]
Ginsenoside Rb1 attenuates cardiomyocyte apoptosis induced by myocardial ischemia reperfusion injury.
Jan 27, 2020
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Biomed Pharmacother. 2020 Jan 28 ;125:109913. Epub 2020 Jan 28. PMID:
32006902
Article Published Date
: Jan 27, 2020
Study Type
: Animal Study
Additional Links
Substances
:
Ginsenosides
Diseases
:
Myocardial Ischemia
Pharmacological Actions
:
Anti-Apoptotic
,
Cardioprotective
[+]
Ginsenoside Rb1 attenuates intestinal ischemia/reperfusion‑induced inflammation and oxidative stress.
Mar 11, 2019
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Mol Med Rep. 2019 Mar 12. Epub 2019 Mar 12. PMID:
30864725
Article Published Date
: Mar 11, 2019
Study Type
: Animal Study
Additional Links
Substances
:
Ginsenosides
Diseases
:
Inflammation
,
Intestinal Ischemia
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Antioxidants
[+]
Ginsenoside Rb1 could inhibit cardiomyocyte apoptosis induced by ischemia-reperfusion, thus alleviating ischemia-reperfusion injury.
Dec 31, 2001
Click here to read the entire abstract
Pubmed Data
: J Huazhong Univ Sci Technolog Med Sci. 2002 ;22(3):212-5. PMID:
12658806
Article Published Date
: Dec 31, 2001
Study Type
: Animal Study
Additional Links
Substances
:
Ginsenosides
Diseases
:
Myocardial Ischemia
Pharmacological Actions
:
Anti-Apoptotic
,
Cardioprotective
[+]
Ginsenoside Rb1 demonstrated inhibitory effects on hypertrophic scars.
Mar 04, 2015
Click here to read the entire abstract
Pubmed Data
: Eur J Pharmacol. 2015 Mar 5 ;750:151-9. Epub 2015 Jan 22. PMID:
25620132
Article Published Date
: Mar 04, 2015
Study Type
: Animal Study
Additional Links
Substances
:
Ginsenosides
Diseases
:
Burns
,
Scars
,
Wound Healing
[+]
Ginsenoside Rb1 exerts anti-inflammatory effects in vitro and in vivo.
Feb 25, 2020
Click here to read the entire abstract
Pubmed Data
: Phytomedicine. 2020 Feb 26 ;69:153197. Epub 2020 Feb 26. PMID:
32146298
Article Published Date
: Feb 25, 2020
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Ginsenosides
Diseases
:
Inflammation
Pharmacological Actions
:
Anti-Inflammatory Agents
,
NF-kappaB Inhibitor
[+]
Ginsenoside Rb1 exerts cardioprotective effects against myocardial ischemia reperfusion injury in diabetic rats.
Sep 30, 2011
Click here to read the entire abstract
Pubmed Data
: Mol Biol Rep. 2011 Oct ;38(7):4327-35. Epub 2010 Nov 27. PMID:
21113666
Article Published Date
: Sep 30, 2011
Study Type
: Animal Study
Additional Links
Substances
:
Ginsenosides
Diseases
:
Diabetic Complications
,
Hypertension
,
Myocardial Infarction
Pharmacological Actions
:
Anti-Apoptotic
,
Cardioprotective
[+]
Ginsenoside Rb1 exerts neuroprotective effects through regulation of Lactobacillus helveticus abundance and GABAA receptor expression.
Dec 31, 2019
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: J Ginseng Res. 2020 Jan ;44(1):86-95. Epub 2018 Sep 19. PMID:
32095096
Article Published Date
: Dec 31, 2019
Study Type
: Animal Study
Additional Links
Substances
:
Ginsenosides
Pharmacological Actions
:
Gastrointestinal Agents
,
Neuroprotective Agents
[+]
Ginsenoside Rb1 exerts protective effects against acetaminophen-induced hepatotoxicity.
Dec 01, 2019
Click here to read the entire abstract
Pubmed Data
: Am J Chin Med. 2019 Dec 2:1-17. Epub 2019 Dec 2. PMID:
31786947
Article Published Date
: Dec 01, 2019
Study Type
: Animal Study
Additional Links
Substances
:
Ginsenosides
Diseases
:
Acetaminophen (Tylenol) Toxicity
,
Liver Damage: Drug-Induced
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Cyclooxygenase 2 Inhibitors
,
Hepatoprotective
,
Interleukin-1 beta downregulation
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
Problem Substances
:
Acetaminophen
,
Paracetamol
[+]
Ginsenoside Rb1 has beneficial effects on oxidative stress injury in rat spinal cords.
Jul 31, 2018
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Exp Ther Med. 2018 Aug ;16(2):1079-1086. Epub 2018 Jun 12. PMID:
30116359
Article Published Date
: Jul 31, 2018
Study Type
: Animal Study
Additional Links
Substances
:
Ginsenosides
Diseases
:
Spinal Cord Injuries
Pharmacological Actions
:
Antioxidants
,
Heme oxygenase-1 up-regulation
,
Nrf2 activation
[+]
Ginsenoside Rb1 has potential for use as a therapeutic agent in osteoarthritis patients.
Mar 31, 2012
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: J Ginseng Res. 2012 Apr ;36(2):161-8. PMID:
23717116
Article Published Date
: Mar 31, 2012
Study Type
: Animal Study
Additional Links
Substances
:
Ginsenosides
Diseases
:
Hydrogen Peroxide Induced Toxicity
,
Osteoarthritis
Pharmacological Actions
:
Antioxidants
,
Chondroprotective
[+]
Ginsenoside Rb1 improves cardiac function and remodeling in heart failure.
Aug 04, 2017
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Exp Anim. 2017 Aug 5 ;66(3):217-228. Epub 2017 Mar 30. PMID:
28367863
Article Published Date
: Aug 04, 2017
Study Type
: Animal Study
Additional Links
Substances
:
Ginsenosides
Diseases
:
Heart Failure
Pharmacological Actions
:
Cardioprotective
Additional Keywords
:
Phytotherapy
[+]
Ginsenoside Rb1 improves cognitive impairment induced by insulin resistance.
Dec 31, 2019
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Biomed Res Int. 2020 ;2020:3905719. Epub 2020 May 20. PMID:
32550230
Article Published Date
: Dec 31, 2019
Study Type
: Animal Study
Additional Links
Substances
:
Ginsenosides
Diseases
:
Cognitive Decline/Dysfunction
,
Insulin Resistance
Pharmacological Actions
:
Neuroprotective Agents
[+]
Ginsenoside Rb1 improves learning and memory ability through its anti-inflammatory effect in Aβ1-40 induced Alzheimer's disease of rats.
Dec 31, 2018
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Am J Transl Res. 2019 ;11(5):2955-2968. Epub 2019 May 15. PMID:
31217866
Article Published Date
: Dec 31, 2018
Study Type
: Animal Study
Additional Links
Substances
:
Ginsenosides
Diseases
:
Alzheimer's Disease
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Interleukin-1 beta downregulation
,
Neuroprotective Agents
[+]
Ginsenoside Rb1 improves postoperative fatigue syndrome by reducing skeletal muscle oxidative stress.
Oct 04, 2014
Click here to read the entire abstract
Pubmed Data
: Eur J Pharmacol. 2014 Oct 5 ;740:480-7. Epub 2014 Jun 27. PMID:
24975098
Article Published Date
: Oct 04, 2014
Study Type
: Animal Study
Additional Links
Substances
:
Ginsenosides
Diseases
:
Fatigue
,
Oxidative Stress
Pharmacological Actions
:
Antioxidants
,
Malondialdehyde Down-regulation
,
Superoxide Dismutase Up-regulation
Additional Keywords
:
Phytotherapy
[+]
Ginsenoside Rb1 inhibit apoptosis in rat model of Alzheimer’s disease.
Dec 31, 2017
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Am J Transl Res. 2018 ;10(3):796-805. Epub 2018 Mar 15. PMID:
29636869
Article Published Date
: Dec 31, 2017
Study Type
: Animal Study
Additional Links
Substances
:
Ginsenosides
Diseases
:
Alzheimer's Disease
Pharmacological Actions
:
Anti-Apoptotic
,
Neuroprotective Agents
[+]
Ginsenoside Rb1 inhibited high glucose-induced oxidative stress, DNA damage, and cell apoptosis in cultured retinal capillary endothelial cells.
Oct 04, 2019
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Int J Mol Sci. 2019 Oct 5 ;20(19). Epub 2019 Oct 5. PMID:
31590397
Article Published Date
: Oct 04, 2019
Study Type
: Animal Study
Additional Links
Substances
:
Ginsenosides
Diseases
:
Diabetic Retinopathy
,
DNA damage
,
Oxidative Stress
Pharmacological Actions
:
Antioxidants
,
Apoptotic
[+]
Ginsenoside Rb1 may attenuate cancer-induced bone pain via inhibiting the activation of microglia and glial-derived proinflammatory cytokines.
Apr 30, 2019
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Exp Ther Med. 2019 May ;17(5):3859-3866. Epub 2019 Mar 18. PMID:
30988771
Article Published Date
: Apr 30, 2019
Study Type
: Animal Study
Additional Links
Substances
:
Ginsenosides
Diseases
:
Cancer: Pain
Pharmacological Actions
:
Antinoceceptive
,
Interleukin-1 beta downregulation
,
Interleukin-6 Downregulation
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
Ginsenoside Rb1 may attenuate the isoflurane/surgery-induced cognitive impairment by inhibiting neuroinflammation and oxidative stress.
Apr 30, 2017
Click here to read the entire abstract
Pubmed Data
: Biomed Environ Sci. 2017 May ;30(5):363-372. PMID:
28549492
Article Published Date
: Apr 30, 2017
Study Type
: Animal Study
Additional Links
Substances
:
Ginsenosides
Diseases
:
Cognitive Decline/Dysfunction
,
Inflammation
,
Oxidative Stress
,
Postoperative Recovery
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Antioxidants
,
Interleukin-6 Downregulation
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
Ginsenoside Rb1 may be an effective treatment to prevent the secondary brain damage induced by stroke.
Apr 17, 2017
Click here to read the entire abstract
Pubmed Data
: J Ethnopharmacol. 2017 Apr 18 ;202:138-146. Epub 2017 Jan 5. PMID:
28065779
Article Published Date
: Apr 17, 2017
Study Type
: Animal Study
Additional Links
Substances
:
Ginsenosides
Diseases
:
Stroke: Attenuation/Recovery
Pharmacological Actions
:
Neuroprotective Agents
[+]
Ginsenoside Rb1 may offer a potential therapeutic option for patients with HIV-associated neurocognitive disorders.
Dec 31, 2017
Click here to read the entire abstract
Pubmed Data
: Am J Chin Med. 2018 ;46(3):551-566. PMID:
29690789
Article Published Date
: Dec 31, 2017
Study Type
: Animal Study
Additional Links
Substances
:
Ginsenosides
Diseases
:
HIV Infections
Pharmacological Actions
:
Neuroprotective Agents
Additional Keywords
:
Blood Brain Barrier
[+]
Ginsenoside Rb1 may prevent ischemia and reperfusion induced cardiac injury.
Mar 21, 2017
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Sci Rep. 2017 Mar 22 ;7:44579. Epub 2017 Mar 22. PMID:
28327605
Article Published Date
: Mar 21, 2017
Study Type
: Animal Study
Additional Links
Substances
:
Ginsenosides
Diseases
:
Myocardial Ischemia
Pharmacological Actions
:
Cardioprotective
[+]
Ginsenoside Rb1 may serve as a potential candidate for the treatment of Parkinson's disease.
Jul 16, 2019
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Aging (Albany NY). 2019 Jul 17 ;11(14):5008-5034. PMID:
31314744
Article Published Date
: Jul 16, 2019
Study Type
: Animal Study
Additional Links
Substances
:
Ginsenosides
Diseases
:
Parkinson's Disease
Pharmacological Actions
:
Neuroprotective Agents
[+]
Ginsenoside Rb1 might effectively release local cerebral ischemia by down-regulating the IL-1 beta expression.
Nov 30, 2013
Click here to read the entire abstract
Pubmed Data
: Zhongguo Zhong Xi Yi Jie He Za Zhi. 2013 Dec ;33(12):1696-700. PMID:
24517072
Article Published Date
: Nov 30, 2013
Study Type
: Animal Study
Additional Links
Substances
:
Ginsenosides
Diseases
:
Brain Ischemia
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Interleukin-1 beta downregulation
[+]
Ginsenoside Rb1 promotes motor functional recovery and axonal regeneration in post-stroke.
Dec 31, 2019
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Brain Res Bull. 2020 Jan ;154:51-60. Epub 2019 Nov 9. PMID:
31715311
Article Published Date
: Dec 31, 2019
Study Type
: Animal Study
Additional Links
Substances
:
Ginsenosides
Diseases
:
Stroke
Pharmacological Actions
:
Neuroprotective Agents
Additional Keywords
:
Nerve Regeneration
[+]
Ginsenoside Rb1 protects against myocardium ischemia/reperfusion injury in diabetic rats.
Dec 31, 2010
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: J Biomed Biotechnol. 2011 ;2011:767930. Epub 2011 Oct 16. PMID:
22013385
Article Published Date
: Dec 31, 2010
Study Type
: Animal Study
Additional Links
Substances
:
Ginsenosides
Diseases
:
Diabetic Complications
,
Myocardial Ischemia
,
Oxidative Stress
Pharmacological Actions
:
Anti-Apoptotic
,
Cardioprotective
[+]
Ginsenoside Rb1 protects against spinal cord ischemia-reperfusion injury.
Sep 01, 2018
Click here to read the entire abstract
Pubmed Data
: Exp Mol Pathol. 2018 Sep 2 ;105(3):229-235. Epub 2018 Sep 2. PMID:
30184471
Article Published Date
: Sep 01, 2018
Study Type
: Animal Study
Additional Links
Substances
:
Ginsenosides
Diseases
:
Ischemia
,
Spinal Cord Injuries
Pharmacological Actions
:
Anti-Apoptotic
[+]
Ginsenoside Rb1 protects dopaminergic neurons from inflammatory injury induced by intranigral lipopolysaccharide injection.
Sep 30, 2019
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Neural Regen Res. 2019 Oct ;14(10):1814-1822. PMID:
31169200
Article Published Date
: Sep 30, 2019
Study Type
: Animal Study
Additional Links
Substances
:
Ginsenosides
Diseases
:
Brain Inflammation
,
Lipopolysaccharide-Induced Toxicity
,
Parkinson's Disease
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Neuroprotective Agents
,
NF-kappaB Inhibitor
[+]
Ginsenoside Rb1 slows the aging process by regulating cell cycle, apoptotic pathway and metabolism of aging mice.
Mar 08, 2020
Click here to read the entire abstract
Pubmed Data
: J Ethnopharmacol. 2020 Mar 9 ;255:112746. Epub 2020 Mar 9. PMID:
32165173
Article Published Date
: Mar 08, 2020
Study Type
: Animal Study
Additional Links
Substances
:
Ginsenosides
Diseases
:
Aging
Pharmacological Actions
:
Anti-Apoptotic
[+]
Ginsenoside Rb1 stimulates adiponectin signaling in C2C12 muscle cells.
Dec 31, 2014
Click here to read the entire abstract
Pubmed Data
: Pharm Biol. 2015 Jan ;53(1):125-32. Epub 2014 Oct 14. PMID:
25311947
Article Published Date
: Dec 31, 2014
Study Type
: Animal Study
Additional Links
Substances
:
Ginsenosides
Diseases
:
Adiponectin: Low Levels
,
Diabetic Complications
Pharmacological Actions
:
Adiponectin upregulation
,
Hypoglycemic Agents
[+]
Ginsenoside Rb3 ameliorates myocardial ischemia-reperfusion injury in rats.
Aug 31, 2011
Click here to read the entire abstract
Pubmed Data
: Pharm Biol. 2011 Sep ;49(9):900-6. Epub 2011 May 19. PMID:
21591990
Article Published Date
: Aug 31, 2011
Study Type
: Animal Study
Additional Links
Substances
:
Ginsenosides
Diseases
:
Myocardial Infarction
Pharmacological Actions
:
Antioxidants
,
Cardioprotective
,
Malondialdehyde Down-regulation
,
Superoxide Dismutase Up-regulation
Additional Keywords
:
Phytotherapy
,
Plant Extracts
[+]
Ginsenoside Rb3 possesses the effect against isoproterenol-induced myocardial injury and heart function impairment.
Jun 24, 2010
Click here to read the entire abstract
Pubmed Data
: Eur J Pharmacol. 2010 Jun 25 ;636(1-3):121-5. Epub 2010 Apr 2. PMID:
20371232
Article Published Date
: Jun 24, 2010
Study Type
: Animal Study
Additional Links
Substances
:
Ginsenosides
Diseases
:
Myocardial Ischemia
Pharmacological Actions
:
Antioxidants
,
Malondialdehyde Down-regulation
,
Superoxide Dismutase Up-regulation
Problem Substances
:
Isoproterenol
[+]
Ginsenoside Rb3 protects cardiomyocytes against ischemia-reperfusion injury.
Dec 31, 2013
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: PLoS One. 2014 ;9(8):e103628. Epub 2014 Aug 1. PMID:
25084093
Article Published Date
: Dec 31, 2013
Study Type
: Animal Study
Additional Links
Substances
:
Ginsenosides
Diseases
:
Myocardial Ischemia
Pharmacological Actions
:
Anti-Apoptotic
,
Cardioprotective
,
NF-kappaB Inhibitor
[+]
Ginsenoside Rb3 provides protective effects against cisplatin-induced nephrotoxicity.
May 15, 2019
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Cell Prolif. 2019 May 16:e12627. Epub 2019 May 16. PMID:
31094028
Article Published Date
: May 15, 2019
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Ginsenosides
Diseases
:
Chemotherapy-Induced Toxicity: Cisplatin
Pharmacological Actions
:
Chemoprotective Agents
[+]
Ginsenoside Rd ameliorates high fat diet-induced obesity.
Mar 31, 2020
Click here to read the entire abstract
Pubmed Data
: Obesity (Silver Spring). 2020 Apr ;28(4):783-792. Epub 2020 Mar 6. PMID:
32144882
Article Published Date
: Mar 31, 2020
Study Type
: Animal Study
Additional Links
Substances
:
Ginsenosides
Diseases
:
High Fat Diet
,
Obesity
Additional Keywords
:
Anti-Obesity Agents
[+]
Ginsenoside Rd attenuates beta-amyloid-induced tau phosphorylation.
May 31, 2013
Click here to read the entire abstract
Pubmed Data
: Neurobiol Dis. 2013 Jun ;54:320-8. Epub 2013 Jan 13. PMID:
23321003
Article Published Date
: May 31, 2013
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Ginsenosides
Diseases
:
Alzheimer's Disease
Pharmacological Actions
:
Neuroprotective Agents
[+]
Ginsenoside Rd attenuates blood-brain barrier damage by suppressing proteasome-mediated signaling after transient forebrain ischemia.
Mar 11, 2020
Click here to read the entire abstract
Pubmed Data
: Neuroreport. 2020 Mar 12. Epub 2020 Mar 12. PMID:
32168101
Article Published Date
: Mar 11, 2020
Study Type
: Animal Study
Additional Links
Substances
:
Ginsenosides
Diseases
:
Brain Ischemia
Pharmacological Actions
:
Neuroprotective Agents
Additional Keywords
:
Blood Brain Barrier
[+]
Ginsenoside Rd contributes the attenuation of cardiac hypertrophy in vivo and in vitro.
Dec 31, 2018
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Biomed Pharmacother. 2019 Jan ;109:1016-1023. Epub 2018 Nov 6. PMID:
30551351
Article Published Date
: Dec 31, 2018
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Ginsenosides
Diseases
:
Cardiac Hypertrophy
Pharmacological Actions
:
Cardioprotective
[+]
Ginsenoside Rd could be a promising agent for amelioration of neuroimmune dysfunction diseases such as multiple sclerosis.
Aug 31, 2014
Click here to read the entire abstract
Pubmed Data
: J Neurosci Res. 2014 Sep ;92(9):1217-26. Epub 2014 May 2. PMID:
24798871
Article Published Date
: Aug 31, 2014
Study Type
: Animal Study
Additional Links
Substances
:
Ginsenosides
Diseases
:
Multiple Sclerosis
Pharmacological Actions
:
Brain-derived neurotrophic factor modulator
,
Interleukin-4 downregulation
[+]
Ginsenoside Rd inhibits apoptosis following spinal cord ischemia/reperfusion injury.
Sep 14, 2014
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Neural Regen Res. 2014 Sep 15 ;9(18):1678-87. PMID:
25374589
Article Published Date
: Sep 14, 2014
Study Type
: Animal Study
Additional Links
Substances
:
Ginsenosides
Diseases
:
Ischemia
,
Spinal Cord Injuries
Pharmacological Actions
:
Anti-Apoptotic
,
Neuroprotective Agents
[+]
Ginsenoside Rd inhibits the expressions of iNOS and COX-2 by suppressing NF-κB.
Feb 28, 2013
Click here to read the entire abstract
Article Publish Status
: This is a free article.
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Pubmed Data
: J Ginseng Res. 2013 Mar ;37(1):54-63. PMID:
23717157
Article Published Date
: Feb 28, 2013
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Ginsenosides
Diseases
:
Inflammation
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Cyclooxygenase 2 Inhibitors
,
NF-kappaB Inhibitor
[+]
Ginsenoside Rd may be a promising anti-angiogenic drug with significant antitumor activity in human breast cancer.
Jun 30, 2017
Click here to read the entire abstract
Pubmed Data
: Oncol Rep. 2017 Jul ;38(1):359-367. Epub 2017 May 19. PMID:
28534996
Article Published Date
: Jun 30, 2017
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Ginsenosides
Diseases
:
Breast Cancer
Pharmacological Actions
:
Anti-Angiogenic
,
Antiproliferative
,
Apoptotic
Additional Keywords
:
Dose Response
[+]
Ginsenoside Rd reverses cognitive deficits by modulating BDNF-dependent CREB pathway in chronic restraint stress.
Jul 15, 2020
Click here to read the entire abstract
Pubmed Data
: Life Sci. 2020 Jul 16 ;258:118107. Epub 2020 Jul 16. PMID:
32682919
Article Published Date
: Jul 15, 2020
Study Type
: Animal Study
Additional Links
Substances
:
Ginsenosides
Diseases
:
Cognitive Decline/Dysfunction
Pharmacological Actions
:
Brain-derived neurotrophic factor modulator
,
Neuroprotective Agents
[+]
Ginsenoside Rd therapy improves histological and functional recovery in a model of inflammatory bowel disease.
May 27, 2020
Click here to read the entire abstract
Pubmed Data
: Phytother Res. 2020 May 28. Epub 2020 May 28. PMID:
32468636
Article Published Date
: May 27, 2020
Study Type
: Animal Study
Additional Links
Substances
:
Ginsenosides
Diseases
:
Inflammatory Bowel Diseases
Pharmacological Actions
:
Gastrointestinal Agents
Problem Substances
:
Indomethacin
[+]
Ginsenoside Re and Rk3 could improve the hematopoietic function of myelosuppressed mice.
Sep 30, 2019
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: J Ginseng Res. 2019 Oct ;43(4):618-624. Epub 2018 Aug 30. PMID:
31695568
Article Published Date
: Sep 30, 2019
Study Type
: Animal Study
Additional Links
Substances
:
Ginsenosides
Diseases
:
Chemotherapy-Induced Toxicity: Cyclophosphamide
Pharmacological Actions
:
Chemoprotective Agents
[+]
Ginsenoside Re could be used to improve high fat diet induced insulin resistance.
Mar 16, 2017
Click here to read the entire abstract
Pubmed Data
: J Agric Food Chem. 2017 Mar 17. Epub 2017 Mar 17. PMID:
28314104
Article Published Date
: Mar 16, 2017
Study Type
: Animal Study
Additional Links
Substances
:
Ginsenosides
Diseases
:
Cognitive Decline/Dysfunction
,
High Fat Diet
,
Insulin Resistance
Pharmacological Actions
:
Anticholesteremic Agents
,
Antioxidants
,
Hypoglycemic Agents
,
Hypolipidemic
[+]
Ginsenoside Re inhibits cardiomyocyte apoptosis
Dec 31, 2001
Click here to read the entire abstract
Pubmed Data
: J Huazhong Univ Sci Technolog Med Sci. 2002 ;22(4):305-9. PMID:
12674765
Article Published Date
: Dec 31, 2001
Study Type
: Animal Study
Additional Links
Substances
:
Ginsenosides
Diseases
:
Myocardial Ischemia
Pharmacological Actions
:
Anti-Apoptotic
,
Cardioprotective
[+]
Ginsenoside Re is a novel angiogenic agent for tissue regeneration.
Mar 31, 2005
Click here to read the entire abstract
Pubmed Data
: Pharm Res. 2005 Apr ;22(4):636-46. Epub 2005 Apr 7. PMID:
15846472
Article Published Date
: Mar 31, 2005
Study Type
: Animal Study
Additional Links
Substances
:
Ginsenosides
Pharmacological Actions
:
Angiogenesis Inducing Agents
,
Regenerative
[+]
Ginsenoside Re may ameliorate inflammation by inhibiting the binding of LPS to TLR4 on macrophages.
Sep 25, 2012
Click here to read the entire abstract
Pubmed Data
: J Agric Food Chem. 2012 Sep 26 ;60(38):9595-602. Epub 2012 Sep 12. PMID:
22849695
Article Published Date
: Sep 25, 2012
Study Type
: Animal Study
Additional Links
Substances
:
Ginsenosides
Diseases
:
Colitis
,
Inflammation
,
Lipopolysaccharide-Induced Toxicity
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Interleukin-1 beta downregulation
,
NF-kappaB Inhibitor
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
Ginsenoside Re possesses the property to attenuate isoproterenol-induced myocardial ischemic injury.
Dec 31, 2017
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Evid Based Complement Alternat Med. 2018 ;2018:8637134. Epub 2018 Apr 22. PMID:
29849732
Article Published Date
: Dec 31, 2017
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Ginsenosides
Diseases
:
Cardiovascular Diseases
Pharmacological Actions
:
Antioxidants
,
Cardioprotective
,
Nrf2 activation
Problem Substances
:
Isoproterenol
[+]
Ginsenoside Re preserves cardiac function and ameliorates left ventricular remodeling in a rat model of myocardial infarction.
Sep 13, 2019
Click here to read the entire abstract
Pubmed Data
: J Cardiovasc Pharmacol. 2019 Sep 14. Epub 2019 Sep 14. PMID:
31599782
Article Published Date
: Sep 13, 2019
Study Type
: Animal Study
Additional Links
Substances
:
Ginsenosides
Diseases
:
Myocardial Infarction
Pharmacological Actions
:
Cardioprotective
[+]
Ginsenoside Rf alleviates dysmenorrhea and inflammation in a model of endometriosis.
Dec 13, 2018
Click here to read the entire abstract
Pubmed Data
: Food Funct. 2018 Dec 14. Epub 2018 Dec 14. PMID:
30547177
Article Published Date
: Dec 13, 2018
Study Type
: Animal Study
Additional Links
Substances
:
Ginsenosides
Diseases
:
Dysmenorrhea
,
Endometriosis
,
Inflammation
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Interleukin-1 beta downregulation
,
Interleukin-6 Downregulation
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
Ginsenoside Rf may be a potential therapeutic agent for treating Alzheimer's disease.
Dec 31, 2017
Click here to read the entire abstract
Pubmed Data
: J Alzheimers Dis. 2018 ;64(1):309-322. PMID:
29865080
Article Published Date
: Dec 31, 2017
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Ginsenosides
Diseases
:
Alzheimer's Disease
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Neuroprotective Agents
[+]
Ginsenoside Rg-1 promoted the wound closure of diabetic foot ulcer.
May 30, 2019
Click here to read the entire abstract
Pubmed Data
: Life Sci. 2019 May 31. Epub 2019 May 31. PMID:
31158376
Article Published Date
: May 30, 2019
Study Type
: Animal Study
Additional Links
Substances
:
Ginsenosides
Diseases
:
Diabetic Ulcer
Pharmacological Actions
:
Anti-Ulcer Agents
,
MicroRNA modulator
[+]
Ginsenoside Rg1 abolish imiquimod-induced psoriasis-like dermatitis.
Sep 08, 2019
Click here to read the entire abstract
Pubmed Data
: J Food Biochem. 2019 Sep 9:e13032. Epub 2019 Sep 9. PMID:
31502279
Article Published Date
: Sep 08, 2019
Study Type
: Animal Study
Additional Links
Substances
:
Ginsenosides
Diseases
:
Psoriasis
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Interleukin-1 beta downregulation
,
Interleukin-22 Downregulation
,
Interleukin-23 Downregulation
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
Ginsenoside Rg1 ameliorates cardiac oxidative stress and inflammation in streptozotocin-induced diabetic rats.
Dec 31, 2018
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Diabetes Metab Syndr Obes. 2019 ;12:1091-1103. Epub 2019 Jul 10. PMID:
31372019
Article Published Date
: Dec 31, 2018
Study Type
: Animal Study
Additional Links
Substances
:
Ginsenosides
Diseases
:
Diabetes: Oxidative Stress
,
Diabetes Mellitus: Type 2
,
Diabetic Complications
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Antioxidants
,
Cardioprotective
,
Heme oxygenase-1 up-regulation
,
Nrf2 activation
[+]
Ginsenoside Rg1 ameliorates diabetic cardiomyopathy.
Mar 31, 2016
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: J Cell Mol Med. 2016 Apr ;20(4):623-31. Epub 2016 Feb 12. PMID:
26869403
Article Published Date
: Mar 31, 2016
Study Type
: Animal Study
Additional Links
Substances
:
Ginsenosides
Diseases
:
Cardiomyopathy
,
Diabetes: Cardiovascular Illness
Pharmacological Actions
:
Anti-Apoptotic
,
Cardioprotective
[+]
Ginsenoside Rg1 ameliorates hippocampal long-term potentiation and memory in an Alzheimer's disease model.
May 31, 2016
Click here to read the entire abstract
Pubmed Data
: Mol Med Rep. 2016 Jun ;13(6):4904-10. Epub 2016 Apr 12. PMID:
27082952
Article Published Date
: May 31, 2016
Study Type
: Animal Study
Additional Links
Substances
:
Ginsenosides
Diseases
:
Alzheimer's Disease
Pharmacological Actions
:
Neuroprotective Agents
[+]
Ginsenoside Rg1 ameliorates liver fibrosis.
May 14, 2018
Click here to read the entire abstract
Pubmed Data
: Biofactors. 2018 May 15. Epub 2018 May 15. PMID:
29761840
Article Published Date
: May 14, 2018
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Ginsenosides
Diseases
:
Chemically-Induced Liver Damage
,
Liver Fibrosis
Pharmacological Actions
:
Anti-Fibrotic
,
Hepatoprotective
[+]
Ginsenoside Rg1 ameliorates oxidative stress and myocardial apoptosis in streptozotocin-induced diabetic rats.
Apr 30, 2015
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: J Zhejiang Univ Sci B. 2015 May ;16(5):344-54. PMID:
25990051
Article Published Date
: Apr 30, 2015
Study Type
: Animal Study
Additional Links
Substances
:
Ginsenosides
Diseases
:
Diabetes: Oxidative Stress
Pharmacological Actions
:
Anti-Apoptotic
,
Cardioprotective
,
Malondialdehyde Down-regulation
[+]
Ginsenoside Rg1 ameliorates rat myocardial ischemia-reperfusion injury.
Dec 31, 2017
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Front Physiol. 2018 ;9:78. Epub 2018 Feb 7. PMID:
29467677
Article Published Date
: Dec 31, 2017
Study Type
: Animal Study
Additional Links
Substances
:
Ginsenosides
Diseases
:
Myocardial Ischemia
Pharmacological Actions
:
Anti-Apoptotic
,
Cardioprotective
[+]
Ginsenoside Rg1 and Acori graminei Rhizoma suppressed neuron cell apoptosis by regulating the expression of miR-873-5p in Alzheimer's disease.
Jun 19, 2018
Click here to read the entire abstract
Pubmed Data
: Neurochem Res. 2018 Jun 20. Epub 2018 Jun 20. PMID:
29926354
Article Published Date
: Jun 19, 2018
Study Type
: Animal Study
Additional Links
Substances
:
Ginsenosides
Diseases
:
Alzheimer's Disease
Pharmacological Actions
:
Neuroprotective Agents
[+]
Ginsenoside Rg1 attenuates adjuvant-induced arthritis in rats.
Aug 14, 2017
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Oncotarget. 2017 Aug 15 ;8(33):55384-55393. Epub 2017 Jul 24. PMID:
28903427
Article Published Date
: Aug 14, 2017
Study Type
: Animal Study
Additional Links
Substances
:
Ginsenosides
Diseases
:
Rheumatoid Arthritis
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Interleukin-6 Downregulation
,
NF-kappaB Inhibitor
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
Ginsenoside Rg1 attenuates cardiomyocyte apoptosis and inflammation via the TLR4/NF-kB/NLRP3 pathway.
Nov 10, 2019
Click here to read the entire abstract
Pubmed Data
: J Cell Biochem. 2019 Nov 11. Epub 2019 Nov 11. PMID:
31709615
Article Published Date
: Nov 10, 2019
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Ginsenosides
Diseases
:
Sepsis
Pharmacological Actions
:
Anti-Apoptotic
,
Anti-Inflammatory Agents
,
Cardioprotective
[+]
Ginsenoside Rg1 attenuates chronic unpredictable mild stress-induced depressive-like effects.
Sep 03, 2019
Click here to read the entire abstract
Pubmed Data
: Neuroreport. 2019 Sep 4 ;30(13):893-900. PMID:
31373969
Article Published Date
: Sep 03, 2019
Study Type
: Animal Study
Additional Links
Substances
:
Ginsenosides
Diseases
:
Depression
,
Stress
Pharmacological Actions
:
Antidepressive Agents
[+]
Ginsenoside Rg1 attenuates cigarette smoke-induced pulmonary epithelial-mesenchymal transition.
Dec 31, 2016
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Biomed Res Int. 2017 ;2017:7171404. Epub 2017 Aug 13. PMID:
29104873
Article Published Date
: Dec 31, 2016
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Ginsenosides
Diseases
:
Lung Injury: Smoke-Induced
[+]
Ginsenoside Rg1 attenuates hepatic insulin resistance induced by high-fat and high-sugar by inhibiting inflammation.
Jul 04, 2019
Click here to read the entire abstract
Pubmed Data
: Eur J Pharmacol. 2019 Jul 5 ;854:247-255. Epub 2019 Apr 16. PMID:
31002778
Article Published Date
: Jul 04, 2019
Study Type
: Animal Study
Additional Links
Substances
:
Ginsenosides
Diseases
:
High Fat Diet
,
High Sugar Diet
,
Inflammation
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Interleukin-1 beta downregulation
,
Interleukin-6 Downregulation
,
NF-kappaB Inhibitor
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
Ginsenoside Rg1 attenuates liver injury induced by D-galactose in mice.
Oct 31, 2018
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Exp Ther Med. 2018 Nov ;16(5):4100-4106. Epub 2018 Sep 11. PMID:
30402153
Article Published Date
: Oct 31, 2018
Study Type
: Animal Study
Additional Links
Substances
:
Ginsenosides
Diseases
:
Chemically-Induced Liver Damage
Pharmacological Actions
:
Antioxidants
,
Hepatoprotective
[+]
Ginsenoside Rg1 can be effective antagonistic structure and function of the pancreas injury induced by D-gal.
Jun 30, 2017
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Exp Ther Med. 2017 Jul ;14(1):616-622. Epub 2017 May 25. PMID:
28672975
Article Published Date
: Jun 30, 2017
Study Type
: Animal Study
Additional Links
Substances
:
Ginsenosides
Pharmacological Actions
:
Antioxidants
,
Malondialdehyde Down-regulation
,
Pancreato Protective Agents
[+]
Ginsenoside Rg1 can inhibit inflammatory reaction, regulate lipid metabolism, and alleviate liver injury in NAFLD.
May 18, 2020
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: ACS Omega. 2020 May 19 ;5(19):10878-10890. Epub 2020 May 5. PMID:
32455208
Article Published Date
: May 18, 2020
Study Type
: Animal Study
Additional Links
Substances
:
Ginsenosides
Diseases
:
Nonalcoholic fatty liver disease (NAFLD)
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Hepatoprotective
,
Hypolipidemic
,
Interleukin-18 down-regulation
,
Interleukin-6 Downregulation
,
Interleukin-8 downregulation
[+]
Ginsenoside Rg1 can significantly inhibit lung inflammation in septic mice.
Apr 30, 2020
Click here to read the entire abstract
Pubmed Data
: Sichuan Da Xue Xue Bao Yi Xue Ban. 2020 May ;51(3):371-375. PMID:
32543145
Article Published Date
: Apr 30, 2020
Study Type
: Animal Study
Additional Links
Substances
:
Ginsenosides
Diseases
:
Sepsis
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Interleukin-1 beta downregulation
,
Interleukin-6 Downregulation
,
NF-kappaB Inhibitor
[+]
Ginsenoside Rg1 carries a therapeutic potential in stroke possibly through a feed-back mechanism by regulating systematic metabolic mediation.
Apr 30, 2015
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Acta Pharm Sin B. 2015 May ;5(3):277-84. Epub 2015 Apr 8. PMID:
26579457
Article Published Date
: Apr 30, 2015
Study Type
: Animal Study
Additional Links
Substances
:
Ginsenosides
Diseases
:
Stroke: Attenuation/Recovery
Pharmacological Actions
:
Neuroprotective Agents
[+]
Ginsenoside Rg1 could alleviate the behavior changes of depressive-like rats.
Sep 30, 2012
Click here to read the entire abstract
Pubmed Data
: Zhongguo Zhong Yao Za Zhi. 2012 Oct ;37(20):3117-21. PMID:
23311165
Article Published Date
: Sep 30, 2012
Study Type
: Animal Study
Additional Links
Substances
:
Ginsenosides
Diseases
:
Depression
Pharmacological Actions
:
Antidepressive Agents
[+]
Ginsenoside Rg1 could be a potential candidate to improve the behavioural deficits in Alzheimer's disease.
Dec 31, 2016
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Oxid Med Cell Longev. 2017 ;2017:6473506. Epub 2017 Oct 24. PMID:
29204248
Article Published Date
: Dec 31, 2016
Study Type
: Transgenic Animal Study
Additional Links
Substances
:
Ginsenosides
Diseases
:
Alzheimer's Disease
Pharmacological Actions
:
Neuroprotective Agents
[+]
Ginsenoside Rg1 could effectively promote the regenerative repair of peripheral nerve injury
Oct 31, 2014
Click here to read the entire abstract
Pubmed Data
: Pak J Pharm Sci. 2014 Nov ;27(6 Suppl):2035-40. PMID:
25410069
Article Published Date
: Oct 31, 2014
Study Type
: Animal Study
Additional Links
Substances
:
Ginsenosides
Diseases
:
Sciatica
Pharmacological Actions
:
Anti-Apoptotic
,
Neuroprotective Agents
Additional Keywords
:
Nerve Regeneration
[+]
Ginsenoside Rg1 could exert its therapeutic effects on intestinal intestinal ischemia/reperfusion injury.
Jan 01, 2016
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Sci Rep. 2016 12 2 ;6:38480. Epub 2016 Dec 2. PMID:
27910952
Article Published Date
: Jan 01, 2016
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Ginsenosides
Diseases
:
Intestinal Ischemia
Pharmacological Actions
:
Anti-Apoptotic
,
Antioxidants
,
Gastroprotective
,
Wnt/β-catenin signaling pathway modulation
[+]
Ginsenoside Rg1 decreases oxidative stress and attenuates cognitive impairment.
Nov 16, 2017
Click here to read the entire abstract
Pubmed Data
: Neurochem Res. 2017 Nov 17. Epub 2017 Nov 17. PMID:
29147958
Article Published Date
: Nov 16, 2017
Study Type
: Animal Study
Additional Links
Substances
:
Ginsenosides
Diseases
:
Cognitive Decline/Dysfunction
Pharmacological Actions
:
Antioxidants
,
Neuroprotective Agents
[+]
Ginsenoside Rg1 exhibited protective effect against transverse aortic constriction-induced left ventricular hypertrophy and cardiac dysfunction.
Jun 30, 2013
Click here to read the entire abstract
Pubmed Data
: J Cardiovasc Pharmacol. 2013 Jul ;62(1):50-7. PMID:
23846802
Article Published Date
: Jun 30, 2013
Study Type
: Animal Study
Additional Links
Substances
:
Ginsenosides
Diseases
:
Cardiac Hypertrophy
Pharmacological Actions
:
Angiogenesis Inducing Agents
[+]
Ginsenoside Rg1 exhibits protective effect against bleomycin-induced pulmonary fibrosis in rats.
Dec 31, 2015
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Biol Pharm Bull. 2016 ;39(8):1284-92. PMID:
27476938
Article Published Date
: Dec 31, 2015
Study Type
: Animal Study
Additional Links
Substances
:
Ginsenosides
Diseases
:
Chemotherapy-Induced Toxicity: Bleomycin
Pharmacological Actions
:
Chemoprotective Agents
[+]
Ginsenoside Rg1 improves fertility and reduces ovarian pathological damages in premature ovarian failure.
Mar 31, 2017
Click here to read the entire abstract
Pubmed Data
: Exp Biol Med (Maywood). 2017 Apr ;242(7):683-691. Epub 2017 Jan 1. PMID:
28178855
Article Published Date
: Mar 31, 2017
Study Type
: Animal Study
Additional Links
Substances
:
Ginsenosides
Diseases
:
Ovarian Failure
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Antioxidants
,
Fertility Agents: Female
[+]
Ginsenoside Rg1 improves the anti-aging ability of hematopoietic microenvironment.
Apr 14, 2015
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: BMC Complement Altern Med. 2015 Apr 15 ;15:119. Epub 2015 Apr 15. PMID:
25881060
Article Published Date
: Apr 14, 2015
Study Type
: Animal Study
Additional Links
Substances
:
Ginsenosides
Diseases
:
Aging
,
Oxidative Stress
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Antioxidants
,
Malondialdehyde Down-regulation
Additional Keywords
:
Plant Extracts
[+]
Ginsenoside Rg1 inhibits dietary-induced obesity and improves obesity-related glucose metabolic disorders.
Feb 28, 2018
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Braz J Med Biol Res. 2018 Mar 1 ;51(4):e7139. Epub 2018 Mar 1. PMID:
29513799
Article Published Date
: Feb 28, 2018
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Ginsenosides
Diseases
:
Obesity
Pharmacological Actions
:
Hypoglycemic Agents
Additional Keywords
:
Anti-Obesity Agents
[+]
Ginsenoside Rg1 inhibits glucagon-induced hepatic gluconeogenesis through Akt-FoxO1 interaction.
Dec 31, 2016
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Theranostics. 2017 ;7(16):4001-4012. Epub 2017 Sep 20. PMID:
29109794
Article Published Date
: Dec 31, 2016
Study Type
: Animal Study
Additional Links
Substances
:
Ginsenosides
Diseases
:
Diabetes Mellitus: Type 2
Pharmacological Actions
:
Hypoglycemic Agents
[+]
Ginsenoside Rg1 inhibits myocardial ischaemia and reperfusion injury.
Dec 31, 2018
Click here to read the entire abstract
Pubmed Data
: Pharmazie. 2019 03 1 ;74(3):157-162. PMID:
30961682
Article Published Date
: Dec 31, 2018
Study Type
: Animal Study
Additional Links
Substances
:
Ginsenosides
Diseases
:
Diabetic Complications
,
Myocardial Ischemia
Pharmacological Actions
:
Cardioprotective
[+]
Ginsenoside Rg1 may be a promising agent for prevention against acute liver injury.
Jun 10, 2018
Click here to read the entire abstract
Pubmed Data
: Int Immunopharmacol. 2018 Jun 11 ;61:266-276. Epub 2018 Jun 11. PMID:
29902710
Article Published Date
: Jun 10, 2018
Study Type
: Animal Study
Additional Links
Substances
:
Ginsenosides
Diseases
:
Inflammation
,
Lipopolysaccharide-Induced Toxicity
,
Liver Damage
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Antioxidants
,
Heme oxygenase-1 up-regulation
,
Hepatoprotective
,
Interleukin-1 beta downregulation
,
Interleukin-6 Downregulation
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
Ginsenoside Rg1 may have protective effects on neuroinflammation and neuronal injury induced by chronic glucocorticoids exposure.
Sep 30, 2017
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Int J Mol Med. 2017 Oct ;40(4):1134-1142. Epub 2017 Aug 9. PMID:
28849171
Article Published Date
: Sep 30, 2017
Study Type
: Animal Study
Additional Links
Substances
:
Ginsenosides
Diseases
:
Brain Inflammation
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Interleukin-18 down-regulation
,
Interleukin-1 beta downregulation
Problem Substances
:
Dexamethasone
[+]
Ginsenoside Rg1 may inhibit liver inflammation and hepatocyte apoptosis through multiple targets to protect liver function.
Mar 19, 2017
Click here to read the entire abstract
Pubmed Data
: Zhonghua Gan Zang Bing Za Zhi. 2017 Mar 20 ;25(3):217-222. PMID:
28482410
Article Published Date
: Mar 19, 2017
Study Type
: Animal Study
Additional Links
Substances
:
Ginsenosides
Diseases
:
Chemically-Induced Liver Damage
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Antioxidants
,
Hepatoprotective
[+]
Ginsenoside Rg1 may protect hepatocytes against alcohol induced injury, through preventing excessive inflammation and hepatocellular apoptosis.
Jan 31, 2018
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Int J Mol Med. 2018 Feb ;41(2):899-907. Epub 2017 Nov 29. PMID:
29207044
Article Published Date
: Jan 31, 2018
Study Type
: Animal Study
Additional Links
Substances
:
Ginsenosides
Diseases
:
Alcoholic Liver Disease
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Interleukin-1 beta downregulation
,
Interleukin-6 Downregulation
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
Ginsenoside Rg1 may represent a novel treatment target for spinal cord injury.
Dec 31, 2016
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Biol Pharm Bull. 2017 ;40(10):1630-1637. PMID:
28966235
Article Published Date
: Dec 31, 2016
Study Type
: Animal Study
Additional Links
Substances
:
Ginsenosides
Diseases
:
Spinal Cord Injuries
Pharmacological Actions
:
Matrix metalloproteinase-2 (MMP-2) inhibitor
,
Matrix metalloproteinase-9 (MMP-9) inhibitor
[+]
Ginsenoside Rg1 may serve as a novel therapeutic agent for the treatment of strokes.
Jan 31, 2018
Click here to read the entire abstract
Pubmed Data
: Mol Med Rep. 2018 Feb ;17(2):3186-3193. Epub 2017 Dec 7. PMID:
29257264
Article Published Date
: Jan 31, 2018
Study Type
: Animal Study
Additional Links
Substances
:
Ginsenosides
Diseases
:
Cerebral Ischemia
Pharmacological Actions
:
Neuroprotective Agents
[+]
Ginsenoside Rg1 may suppress cigarette smoke-induced airway fibrosis in pulmonary fibroblasts and COPD rats.
Dec 31, 2016
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Biomed Res Int. 2017 ;2017:6510198. Epub 2017 Mar 21. PMID:
28421197
Article Published Date
: Dec 31, 2016
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Ginsenosides
Diseases
:
Chronic Obstructive Pulmonary Disease
,
Lung Injury: Smoke-Induced
,
Smoking: Pulmonary
Pharmacological Actions
:
Anti-Fibrotic
Additional Keywords
:
Anti-Fibrotic
,
Chronic Obstructive Pulmonary Disease
,
Ginsenosides
,
Lung Injury: Smoke-Induced
,
Smoking: Pulmonary
[+]
Ginsenoside Rg1 might be an effective approach for the prevention against acute liver injury.
Jul 01, 2018
Click here to read the entire abstract
Pubmed Data
: Environ Toxicol. 2018 Jul 2. Epub 2018 Jul 2. PMID:
29964319
Article Published Date
: Jul 01, 2018
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Ginsenosides
Diseases
:
Chemically-Induced Liver Damage
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Antioxidants
,
Cyclooxygenase 2 Inhibitors
,
Hepatoprotective
,
Interleukin-1 beta downregulation
,
Interleukin-6 Downregulation
,
Nrf2 activation
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
Ginsenoside Rg1 might have the potential to reduce body fat accumulation in the early stage of obesity.
Dec 31, 2016
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: J Ginseng Res. 2017 Jan ;41(1):23-30. Epub 2015 Dec 17. PMID:
28123318
Article Published Date
: Dec 31, 2016
Study Type
: Animal Study
Additional Links
Substances
:
Ginsenosides
Diseases
:
Obesity
Additional Keywords
:
Anti-Obesity Agents
[+]
Ginsenoside Rg1 nanoparticles could penetrate the blood-brain barrier with high concentration in brain tissue to reduce the cerebral infarction volume.
Dec 31, 2016
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Int J Nanomedicine. 2017 ;12:6477-6486. Epub 2017 Sep 5. PMID:
28919749
Article Published Date
: Dec 31, 2016
Study Type
: Animal Study
Additional Links
Substances
:
Ginsenosides
Diseases
:
Stroke
Pharmacological Actions
:
Neuroprotective Agents
Additional Keywords
:
Blood Brain Barrier
[+]
Ginsenoside Rg1 plays a neuroprotective role in brain repair following neonatal hypoxia/ischemia brain injury.
Dec 31, 2016
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Pediatr Res. 2017 01 ;81(1-1):120-126. Epub 2016 Sep 15. PMID:
27632778
Article Published Date
: Dec 31, 2016
Study Type
: Animal Study
Additional Links
Substances
:
Ginsenosides
Pharmacological Actions
:
Anti-Apoptotic
,
Neuroprotective Agents
[+]
Ginsenoside Rg1 prevents acetaminophen-induced oxidative stress and apoptosis.
Jan 03, 2019
Click here to read the entire abstract
Pubmed Data
: J Asian Nat Prod Res. 2019 Jan 4:1-16. Epub 2019 Jan 4. PMID:
30608002
Article Published Date
: Jan 03, 2019
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Ginsenosides
Diseases
:
Acetaminophen (Tylenol) Toxicity
Pharmacological Actions
:
Anti-Apoptotic
,
Antioxidants
,
Hepatoprotective
,
Nrf2 activation
Problem Substances
:
Acetaminophen
,
Paracetamol
[+]
Ginsenoside Rg1 prevents chemotherapy-induced cognitive impairment.
Jan 17, 2019
Click here to read the entire abstract
Pubmed Data
: Mol Neurobiol. 2019 Jan 18. Epub 2019 Jan 18. PMID:
30659419
Article Published Date
: Jan 17, 2019
Study Type
: Animal Study
Additional Links
Substances
:
Ginsenosides
Diseases
:
Chemobrain
,
Chemotherapy-Induced Neurotoxicity
Pharmacological Actions
:
Chemoprotective Agents
,
Neuroprotective Agents
[+]
Ginsenoside Rg1 prevents chronic stress-induced depression-Like behaviors.
Dec 31, 2017
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Cell Physiol Biochem. 2018 ;48(6):2470-2482. Epub 2018 Aug 17. PMID:
30121663
Article Published Date
: Dec 31, 2017
Study Type
: Animal Study
Additional Links
Substances
:
Ginsenosides
Diseases
:
Depression
Pharmacological Actions
:
Antidepressive Agents
[+]
Ginsenoside Rg1 prevents cognitive impairment and hippocampus senescence in a rat model of D-galactose-induced aging.
Dec 31, 2013
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: PLoS One. 2014 ;9(6):e101291. Epub 2014 Jun 30. PMID:
24979747
Article Published Date
: Dec 31, 2013
Study Type
: Animal Study
Additional Links
Substances
:
Ginsenosides
Diseases
:
Aging: Brain
Pharmacological Actions
:
Antioxidants
,
Neuroprotective Agents
[+]
Ginsenoside Rg1 produces an antidepressant like effect as a result from modulation of the miR-134 signalling.
Jan 14, 2018
Click here to read the entire abstract
Pubmed Data
: Neuropharmacology. 2018 03 15 ;131:364-376. Epub 2018 Jan 9. PMID:
29329879
Article Published Date
: Jan 14, 2018
Study Type
: Animal Study
Additional Links
Substances
:
Ginsenosides
Diseases
:
Depression
Pharmacological Actions
:
Antidepressive Agents
,
MicroRNA modulator
[+]
ginsenoside Rg1 promoted cerebral angiogenesis through increasing the expression of VEGF via PI3K/Akt/mTOR signaling pathway after ischemic stroke.
May 23, 2019
Click here to read the entire abstract
Pubmed Data
: Eur J Pharmacol. 2019 May 24:172418. Epub 2019 May 24. PMID:
31132356
Article Published Date
: May 23, 2019
Study Type
: Animal Study
Additional Links
Substances
:
Ginsenosides
Diseases
:
Stroke: Ischemic
Pharmacological Actions
:
Angiogenesis Inducing Agents
,
Neuroprotective Agents
[+]
Ginsenoside Rg1 protects against acetaminophen-induced liver injury.
Jul 16, 2018
Click here to read the entire abstract
Pubmed Data
: Regul Toxicol Pharmacol. 2018 Jul 17 ;98:58-68. Epub 2018 Jul 17. PMID:
30030101
Article Published Date
: Jul 16, 2018
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Ginsenosides
Diseases
:
Acetaminophen (Tylenol) Toxicity
,
Chemically-Induced Liver Damage
Pharmacological Actions
:
Antioxidants
,
Hepatoprotective
,
Nrf2 activation
Problem Substances
:
Acetaminophen
,
Paracetamol
[+]
Ginsenoside Rg1 protects against cigarette smoke-induced airway remodeling.
Dec 31, 2019
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Am J Transl Res. 2020 ;12(2):493-506. Epub 2020 Feb 15. PMID:
32194898
Article Published Date
: Dec 31, 2019
Study Type
: Animal Study
Additional Links
Substances
:
Ginsenosides
Diseases
:
Lung Injury: Smoke-Induced
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Interleukin-6 Downregulation
,
Transforming growth factor beta (TGF-β) inhibitor
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
Ginsenoside Rg1 protects against non-alcoholic fatty liver disease.
Oct 31, 2018
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Biol Pharm Bull. 2018 Nov 1 ;41(11):1638-1644. Epub 2018 Aug 21. PMID:
30135326
Article Published Date
: Oct 31, 2018
Study Type
: Animal Study
Additional Links
Substances
:
Ginsenosides
Diseases
:
Nonalcoholic fatty liver disease (NAFLD)
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Hepatoprotective
[+]
Ginsenoside Rg1 protects against sepsis-associated encephalopathy.
Dec 31, 2016
Click here to read the entire abstract
Pubmed Data
: J Surg Res. 2017 01 ;207:181-189. Epub 2016 Aug 31. PMID:
27979475
Article Published Date
: Dec 31, 2016
Study Type
: Animal Study
Additional Links
Substances
:
Ginsenosides
Diseases
:
Encephalopathy
,
Sepsis
Pharmacological Actions
:
Anti-Apoptotic
,
Neuroprotective Agents
[+]
Ginsenoside Rg1 protects mice against streptozotocin-induced type 1 diabetes.
Jan 04, 2020
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Eur J Pharmacol. 2020 Jan 5 ;866:172801. Epub 2019 Nov 16. PMID:
31738935
Article Published Date
: Jan 04, 2020
Study Type
: Animal Study
Additional Links
Substances
:
Ginsenosides
Diseases
:
Diabetes Mellitus: Type 1
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Antioxidants
,
Heme oxygenase-1 up-regulation
,
Interleukin-18 down-regulation
,
Interleukin-1 beta downregulation
,
Nrf2 activation
[+]
Ginsenoside Rg1 protects rat cardiomyocyte from hypoxia/reoxygenation oxidative injury.
Aug 31, 2009
Click here to read the entire abstract
Pubmed Data
: J Cell Biochem. 2009 Sep 1 ;108(1):117-24. PMID:
19530220
Article Published Date
: Aug 31, 2009
Study Type
: Animal Study
Additional Links
Substances
:
Ginsenosides
Diseases
:
Hypoxia
,
Oxidative Stress
Pharmacological Actions
:
Antioxidants
,
Cardioprotective
[+]
Ginsenoside Rg1 provides neuroprotection against blood brain barrier disruption and neurological injury.
Jun 14, 2014
Click here to read the entire abstract
Pubmed Data
: Phytomedicine. 2014 Jun 15 ;21(7):998-1003. Epub 2014 Jan 22. PMID:
24462216
Article Published Date
: Jun 14, 2014
Study Type
: Animal Study
Additional Links
Substances
:
Ginsenosides
Diseases
:
Brain Ischemia
Pharmacological Actions
:
Neuroprotective Agents
[+]
Ginsenoside Rg1 significantly reduces liver damage in an acute liver failure model.
Dec 31, 2013
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Evid Based Complement Alternat Med. 2014 ;2014:538059. Epub 2014 Oct 28. PMID:
25431611
Article Published Date
: Dec 31, 2013
Study Type
: Animal Study
Additional Links
Substances
:
Ginsenosides
Diseases
:
Liver Failure: Acute
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Hepatoprotective
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
Ginsenoside Rg1 treatment improves memory in middle-aged mice.
Apr 29, 2015
Click here to read the entire abstract
Pubmed Data
: Neuroscience. 2015 Apr 30 ;292:81-9. Epub 2015 Feb 25. PMID:
25724866
Article Published Date
: Apr 29, 2015
Study Type
: Animal Study
Additional Links
Substances
:
Ginsenosides
Diseases
:
Aging: Brain
,
Cognitive Decline/Dysfunction
Pharmacological Actions
:
Neuroprotective Agents
[+]
Ginsenoside Rg1, a compound found within ginseng, improves male copulatory behavior in mice.
Sep 14, 2009
Click here to read the entire abstract
Pubmed Data
: J Sex Med. 2009 Sep 14. Epub 2009 Sep 14. PMID:
19751391
Article Published Date
: Sep 14, 2009
Study Type
: Animal Study
Additional Links
Substances
:
Ginsenosides
Diseases
:
Erectile Dysfunction
,
Low Libido
,
Low Testosterone
Pharmacological Actions
:
Aphrodisiac
,
Nitric Oxide Enhancer
,
Secretagogue
[+]
Ginsenoside Rg2 inhibits adipogenesis in 3T3-L1 preadipocytes and suppresses obesity in high-fat-diet-induced obesity.
Jun 18, 2019
Click here to read the entire abstract
Pubmed Data
: Food Funct. 2019 Jun 19 ;10(6):3603-3614. PMID:
31161181
Article Published Date
: Jun 18, 2019
Study Type
: Animal Study
Additional Links
Substances
:
Ginsenosides
Diseases
:
High Fat Diet
,
Obesity
Pharmacological Actions
:
Hypolipidemic
Additional Keywords
:
Anti-Obesity Agents
[+]
Ginsenoside Rg2 may represent a potential treatment strategy for vascular dementia or other ischemic insults.
Feb 11, 2008
Click here to read the entire abstract
Pubmed Data
: J Ethnopharmacol. 2008 Feb 12 ;115(3):441-8. Epub 2007 Oct 25. PMID:
18083315
Article Published Date
: Feb 11, 2008
Study Type
: Animal Study
Additional Links
Substances
:
Ginsenosides
Diseases
:
Dementia
,
Memory Disorders
Pharmacological Actions
:
Anti-Apoptotic
,
Heat Shock Protein Down-Regulation
,
Neuroprotective Agents
[+]
Ginsenoside Rg2 produces an antidepressant-like effects in mice in part through promoting the hippocampal BDNF signalling pathway.
Aug 21, 2017
Click here to read the entire abstract
Pubmed Data
: Brain Res Bull. 2017 Aug 22. Epub 2017 Aug 22. PMID:
28842305
Article Published Date
: Aug 21, 2017
Study Type
: Animal Study
Additional Links
Substances
:
Ginsenosides
Diseases
:
Depression
Pharmacological Actions
:
Antidepressive Agents
,
Brain-derived neurotrophic factor modulator
[+]
Ginsenoside Rg3 alleviates lipopolysaccharide-induced learning and memory impairments.
Sep 29, 2013
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Biomol Ther (Seoul). 2013 Sep 30 ;21(5):381-90. PMID:
24244826
Article Published Date
: Sep 29, 2013
Study Type
: Animal Study
Additional Links
Substances
:
Ginsenosides
Diseases
:
Brain Inflammation
,
Lipopolysaccharide-Induced Toxicity
,
Memory Disorders
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Cyclooxygenase 2 Inhibitors
,
Interleukin-1 beta downregulation
,
Neuroprotective Agents
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
Ginsenoside Rg3 ameliorates acute exacerbation of COPD by suppressing neutrophil migration
Apr 07, 2020
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Int Immunopharmacol. 2020 Apr 8 ;83:106449. Epub 2020 Apr 8. PMID:
32278128
Article Published Date
: Apr 07, 2020
Study Type
: Animal Study
Additional Links
Substances
:
Ginsenosides
Diseases
:
Chronic Obstructive Pulmonary Disease
Pharmacological Actions
:
Anti-Inflammatory Agents
[+]
Ginsenoside Rg3 ameliorates lipopolysaccharide-induced acute lung injury.
Apr 30, 2016
Click here to read the entire abstract
Pubmed Data
: Int Immunopharmacol. 2016 May ;34:53-59. Epub 2016 Feb 24. PMID:
26921732
Article Published Date
: Apr 30, 2016
Study Type
: Animal Study
Additional Links
Substances
:
Ginsenosides
Diseases
:
Lipopolysaccharide-Induced Toxicity
,
Lung Injury: Acute
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Interleukin-1 beta downregulation
,
Interleukin-6 Downregulation
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
Ginsenoside Rg3 attenuates aluminum-induced osteoporosis.
Mar 15, 2020
Click here to read the entire abstract
Pubmed Data
: Biol Trace Elem Res. 2020 Mar 16. Epub 2020 Mar 16. PMID:
32173789
Article Published Date
: Mar 15, 2020
Study Type
: Animal Study
Additional Links
Substances
:
Ginsenosides
Diseases
:
Aluminum Toxicity
,
Osteoporosis
Pharmacological Actions
:
Antioxidants
Problem Substances
:
Aluminum
[+]
Ginsenoside Rg3 attenuates lipopolysaccharide-induced acute lung injury.
Dec 31, 2017
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Front Pharmacol. 2018 ;9:850. Epub 2018 Aug 2. PMID:
30116194
Article Published Date
: Dec 31, 2017
Study Type
: Animal Study
Additional Links
Substances
:
Ginsenosides
Diseases
:
Inflammation
,
Lipopolysaccharide-Induced Toxicity
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Interleukin-1 beta downregulation
,
Interleukin-6 Downregulation
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
Ginsenoside Rg3 attenuates microglia activation following systemic lipopolysaccharide treatment in mice.
Dec 31, 2011
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Biol Pharm Bull. 2012 ;35(9):1546-52. PMID:
22975507
Article Published Date
: Dec 31, 2011
Study Type
: Animal Study
Additional Links
Substances
:
Ginsenosides
Diseases
:
Brain: Microglial Activation
,
Brain Inflammation
,
Lipopolysaccharide-Induced Toxicity
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Cyclooxygenase 2 Inhibitors
,
Interleukin-1 beta downregulation
,
Interleukin-6 Downregulation
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
Additional Keywords
:
Phytotherapy
,
Plant Extracts
[+]
Ginsenoside Rg3 attenuates myocardial ischemia/reperfusion injury.
May 31, 2015
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Mol Med Rep. 2015 Jun ;11(6):4518-24. Epub 2015 Feb 11. PMID:
25672441
Article Published Date
: May 31, 2015
Study Type
: Animal Study
Additional Links
Substances
:
Ginsenosides
Diseases
:
Myocardial Ischemia
Pharmacological Actions
:
Antioxidants
,
Bcl-2 protein down-regulation
,
Cardioprotective
,
Superoxide Dismutase Up-regulation
[+]
Ginsenoside Rg3 could enhance the efficacy of erlotinib to inhibit the proliferation of pancreatic cancer cells.
Oct 12, 2017
Click here to read the entire abstract
Pubmed Data
: Biomed Pharmacother. 2017 Oct 13 ;96:619-625. Epub 2017 Oct 13. PMID:
29035827
Article Published Date
: Oct 12, 2017
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Ginsenosides
Diseases
:
Pancreatic Cancer
Pharmacological Actions
:
Antiproliferative
,
Apoptotic
,
Chemotherapeutic
Additional Keywords
:
Chemotherapeutic Synergy: Erlotinib
[+]
Ginsenoside Rg3 could improve exercise performance and resist fatigue possibly through elevating SIRT1 deacetylase activity.
Oct 31, 2018
Click here to read the entire abstract
Pubmed Data
: Toxicology. 2018 Nov 1 ;409:144-151. Epub 2018 Aug 23. PMID:
30144466
Article Published Date
: Oct 31, 2018
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Ginsenosides
Diseases
:
Athletic Performance
,
Fatigue: Excercise-Induced
Pharmacological Actions
:
SIRT1 Activator
[+]
Ginsenoside Rg3 decreases fibrotic and invasive nature of endometriosis.
Dec 14, 2017
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Sci Rep. 2017 Dec 15 ;7(1):17670. Epub 2017 Dec 15. PMID:
29247225
Article Published Date
: Dec 14, 2017
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Ginsenosides
Diseases
:
Endometriosis
Pharmacological Actions
:
Anti-Fibrotic
,
Matrix metalloproteinase-2 (MMP-2) inhibitor
,
Matrix metalloproteinase-9 (MMP-9) inhibitor
,
MicroRNA modulator
[+]
Ginsenoside Rg3 enhances the antitumor effects of radiotherapy for colorectal cancer
Dec 31, 2017
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Evid Based Complement Alternat Med. 2018 ;2018:1580427. Epub 2018 Mar 18. PMID:
29743919
Article Published Date
: Dec 31, 2017
Study Type
: Animal Study
Additional Links
Substances
:
Ginsenosides
Diseases
:
Colorectal Cancer
Pharmacological Actions
:
Anti-Inflammatory Agents
,
NF-kappaB Inhibitor
,
Radiosensitizer
[+]
Ginsenoside Rg3 has an analgesic effects.
Dec 31, 2015
Click here to read the entire abstract
Pubmed Data
: Eur Surg Res. 2016 ;57(3-4):211-223. Epub 2016 Jul 22. PMID:
27441690
Article Published Date
: Dec 31, 2015
Study Type
: Animal Study
Additional Links
Substances
:
Ginsenosides
Diseases
:
Pain
Pharmacological Actions
:
Analgesics
,
Antinoceceptive
[+]
Ginsenoside Rg3 has antidepressant effects via promotion of the hippocampal BDNF signalling pathway.
Dec 23, 2016
Click here to read the entire abstract
Pubmed Data
: J Nat Med. 2016 Dec 24. Epub 2016 Dec 24. PMID:
28013484
Article Published Date
: Dec 23, 2016
Study Type
: Animal Study
Additional Links
Substances
:
Ginsenosides
Diseases
:
Depression
Pharmacological Actions
:
Antidepressive Agents
Additional Keywords
:
antidepressants
,
Antidepressive Agents
,
depression
,
Ginsenoside Rg3
,
Ginsenosides
,
hippocampal BDNF
[+]
Ginsenoside Rg3 has anxiolytic-like effects on chronic unpredictable stress in rats.
May 16, 2018
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Sci Rep. 2018 May 17 ;8(1):7741. Epub 2018 May 17. PMID:
29773855
Article Published Date
: May 16, 2018
Study Type
: Animal Study
Additional Links
Substances
:
Ginsenosides
Diseases
:
Anxiety
Pharmacological Actions
:
Anti-Anxiety Agents
[+]
Ginsenoside Rg3 improves cyclophosphamide-induced immunocompetence in Balb/c mice.
Jun 30, 2019
Click here to read the entire abstract
Pubmed Data
: Int Immunopharmacol. 2019 Jul ;72:98-111. Epub 2019 Apr 8. PMID:
30974284
Article Published Date
: Jun 30, 2019
Study Type
: Animal Study
Additional Links
Substances
:
Ginsenosides
Diseases
:
Chemotherapy-Induced Toxicity: Cyclophosphamide
Pharmacological Actions
:
Chemoprotective Agents
[+]
Ginsenoside Rg3 improves erectile function in streptozotocin-induced diabetic rats.
Feb 28, 2015
Click here to read the entire abstract
Pubmed Data
: J Sex Med. 2015 Mar ;12(3):611-20. Epub 2014 Dec 1. PMID:
25442300
Article Published Date
: Feb 28, 2015
Study Type
: Animal Study
Additional Links
Substances
:
Ginsenosides
Diseases
:
Diabetic Complications
,
Erectile Dysfunction
Pharmacological Actions
:
Malondialdehyde Down-regulation
,
Nitric Oxide Inhibitor
,
Superoxide Dismutase Up-regulation
[+]
Ginsenoside Rg3 induces ginsenoside Rb1-comparable cardioprotective effects independent of reducing blood pressure in spontaneously hypertensive rats.
Oct 31, 2017
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Exp Ther Med. 2017 Nov ;14(5):4977-4985. Epub 2017 Sep 22. PMID:
29201202
Article Published Date
: Oct 31, 2017
Study Type
: Animal Study
Additional Links
Substances
:
Ginsenosides
Diseases
:
Hypertension
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Cardioprotective
,
Interleukin-6 Downregulation
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
Ginsenoside Rg3 inhibition of vasculogenic mimicry in pancreatic cancer.
Aug 31, 2014
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Int J Oncol. 2014 Sep ;45(3):1065-72. Epub 2014 Jun 16. PMID:
24938458
Article Published Date
: Aug 31, 2014
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Ginsenosides
Diseases
:
Pancreatic Cancer
Pharmacological Actions
:
Antineoplastic Agents
,
Matrix metalloproteinase-2 (MMP-2) inhibitor
,
Matrix metalloproteinase-9 (MMP-9) inhibitor
[+]
Ginsenoside Rg3 inhibits epithelial-mesenchymal transition and invasion of lung cancer by down-regulating FUT4.
Jan 11, 2016
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Oncotarget. 2016 Jan 12 ;7(2):1619-32. PMID:
26636541
Article Published Date
: Jan 11, 2016
Study Type
: Animal Study
Additional Links
Substances
:
Ginsenosides
Diseases
:
Cancer Metastasis
,
Lung Cancer
Pharmacological Actions
:
Anti-metastatic
,
E-cadherin down-regulation
[+]
Ginsenoside Rg3 inhibits melanoma cell proliferation through down-regulation of histone deacetylase 3.
Dec 31, 2013
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: PLoS One. 2014 ;9(12):e115401. Epub 2014 Dec 18. PMID:
25521755
Article Published Date
: Dec 31, 2013
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Ginsenosides
Diseases
:
Melanoma
Pharmacological Actions
:
Antineoplastic Agents
,
Antiproliferative
,
Histone deacetylase inhibitor
,
Tumor Suppressor Protein p53 Upregulation
[+]
Ginsenoside Rg3 inhibits migration and invasion, and promotes apoptosis of Caco-2 cells.
Jan 07, 2019
Click here to read the entire abstract
Pubmed Data
: Exp Mol Pathol. 2019 Jan 8 ;106:131-138. Epub 2019 Jan 8. PMID:
30633886
Article Published Date
: Jan 07, 2019
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Ginsenosides
Diseases
:
Colorectal Cancer
Pharmacological Actions
:
Anti-metastatic
,
Antiproliferative
,
Apoptotic
,
Matrix metalloproteinase-9 (MMP-9) inhibitor
[+]
Ginsenoside Rg3 might be a useful agent for the treatment of metastatic thyroid cancers.
Aug 31, 2018
Click here to read the entire abstract
Pubmed Data
: J Med Food. 2018 Sep ;21(9):849-857. Epub 2018 Aug 23. PMID:
30136914
Article Published Date
: Aug 31, 2018
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Ginsenosides
Diseases
:
Thyroid Cancer
Pharmacological Actions
:
Anti-metastatic
,
Matrix metalloproteinase-2 (MMP-2) inhibitor
,
Matrix metalloproteinase-9 (MMP-9) inhibitor
[+]
Ginsenoside Rg3 mitigates atherosclerosis progression in diabetic mice.
Dec 31, 2017
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Front Pharmacol. 2018 ;9:464. Epub 2018 May 9. PMID:
29867472
Article Published Date
: Dec 31, 2017
Study Type
: Animal Study
Additional Links
Substances
:
Ginsenosides
Diseases
:
Atherosclerosis
Pharmacological Actions
:
Anti-atherogenic
[+]
Ginsenoside Rg3 nanoparticle may suppress the expression of VEGF, MMP-9 and HIF-1α in Lewis lung cancer mice.
Jun 17, 2016
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Beijing Da Xue Xue Bao Yi Xue Ban. 2016 Jun 18 ;48(3):496-501. PMID:
27318914
Article Published Date
: Jun 17, 2016
Study Type
: Animal Study
Additional Links
Substances
:
Ginsenosides
Diseases
:
Lung Cancer
Pharmacological Actions
:
Antiproliferative
,
Hypoxia inducible factor-1 alpha (HIF-1α) inhibitor
,
Matrix metalloproteinase-9 (MMP-9) inhibitor
,
Vascular Endothelial Growth Factor Inhibitors
[+]
Ginsenoside Rg3 possessed the effect of improving myocardial ischemia/reperfusion-induced cardiac function impairment.
Dec 31, 2015
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Evid Based Complement Alternat Med. 2016 ;2016:6967853. Epub 2016 Dec 26. PMID:
28105061
Article Published Date
: Dec 31, 2015
Study Type
: Animal Study
Additional Links
Substances
:
Ginsenosides
Diseases
:
Ischemia: Myocardial
Pharmacological Actions
:
Anti-Apoptotic
,
Anti-Inflammatory Agents
,
Cardioprotective
[+]
Ginsenoside Rg3 prolongs survival of the orthotopic hepatocellular carcinoma model.
Dec 31, 2018
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Anal Cell Pathol (Amst). 2019 ;2019:3815786. Epub 2019 Aug 26. PMID:
31534898
Article Published Date
: Dec 31, 2018
Study Type
: Animal Study
Additional Links
Substances
:
Ginsenosides
Diseases
:
Liver Cancer
Pharmacological Actions
:
Angiogenesis Inhibitors
,
Apoptotic
,
Chemotherapeutic
[+]
Ginsenoside Rg3 promotes cytotoxicity and apoptosis of Paclitaxel by inhibiting NF-κB signalling.
Feb 19, 2017
Click here to read the entire abstract
Pubmed Data
: Biomed Pharmacother. 2017 Feb 20 ;89:227-232. Epub 2017 Feb 20. PMID:
28231544
Article Published Date
: Feb 19, 2017
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Ginsenosides
Diseases
:
Breast Cancer: Triple Negative
Pharmacological Actions
:
Bcl-2 protein down-regulation
,
Chemosensitizer
,
NF-kappaB Inhibitor
Additional Keywords
:
Chemothapeutic Synergy: Paclitaxel
[+]
Ginsenoside Rg3 significantly inhibited growth and angiogenesis of ovarian cancer when used alone or combined with cyclophosphamide.
Apr 04, 2007
Click here to read the entire abstract
Pubmed Data
: Chin Med J (Engl). 2007 Apr 5 ;120(7):584-8. PMID:
17442207
Article Published Date
: Apr 04, 2007
Study Type
: Animal Study
Additional Links
Substances
:
Ginsenosides
Diseases
:
Chemotherapy-Induced Toxicity: Cyclophosphamide
,
Ovarian Cancer
Pharmacological Actions
:
Angiogenesis Inhibitors
,
Antiproliferative
,
Vascular Endothelial Growth Factor Inhibitors
Additional Keywords
:
Natural Substance/Drug Synergy
[+]
Ginsenoside Rg3 stereoisomers differentially inhibit vascular smooth muscle cell proliferation and migration in diabetic atherosclerosis.
Mar 21, 2018
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: J Cell Mol Med. 2018 Mar 22. Epub 2018 Mar 22. PMID:
29566305
Article Published Date
: Mar 21, 2018
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Ginsenosides
Diseases
:
Atherosclerosis
,
Diabetic Complications
[+]
Ginsenoside Rg3 suppresses angiogenesis in developing endometrial lesions.
Dec 31, 2016
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: PLoS One. 2017 ;12(11):e0186520. Epub 2017 Nov 15. PMID:
29140979
Article Published Date
: Dec 31, 2016
Study Type
: Animal Study
Additional Links
Substances
:
Ginsenosides
Diseases
:
Endometriosis
Pharmacological Actions
:
Anti-Angiogenic
[+]
Ginsenoside Rg3 targets cancer stem cells and tumor angiogenesis to inhibit colorectal cancer progression in vivo.
Dec 31, 2017
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Int J Oncol. 2018 Jan ;52(1):127-138. Epub 2017 Nov 1. PMID:
29115601
Article Published Date
: Dec 31, 2017
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Ginsenosides
Diseases
:
Colorectal Cancer
Pharmacological Actions
:
Angiogenesis Inhibitors
,
Antiproliferative
Additional Keywords
:
Cancer Stem Cells
,
Chemothapeutic Synergy: 5-flourouracil
,
Chemotherapeutic Synergy: Oxaliplatin
[+]
Ginsenoside Rg3 was effective in ameliorating depressive-like behavior induced by immune activation.
Aug 15, 2017
Click here to read the entire abstract
Pubmed Data
: J Agric Food Chem. 2017 Aug 16 ;65(32):6861-6869. Epub 2017 Aug 7. PMID:
28762741
Article Published Date
: Aug 15, 2017
Study Type
: Animal Study
Additional Links
Substances
:
Ginsenosides
Diseases
:
Depression
,
Lipopolysaccharide-Induced Toxicity
Pharmacological Actions
:
Antidepressive Agents
,
Immunomodulatory
Additional Keywords
:
Plant Extracts
[+]
Ginsenoside Rg3-enriched Korean red ginseng enhances blood pressure stability in spontaneously hypertensive rats.
Aug 31, 2016
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Integr Med Res. 2016 Sep ;5(3):223-229. Epub 2016 Jun 3. PMID:
28462122
Article Published Date
: Aug 31, 2016
Study Type
: Animal Study
Additional Links
Substances
:
Ginseng
,
Ginsenosides
Diseases
:
Hypertension
Pharmacological Actions
:
Antihypertensive Agents
[+]
Ginsenoside Rg3-RGE could be potentially be used as an antiplatelet therapeutic agent against platelet-mediated cardiovascular disorders.
Sep 30, 2017
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: J Ginseng Res. 2017 Oct ;41(4):548-555. Epub 2017 Jan 13. PMID:
29021703
Article Published Date
: Sep 30, 2017
Study Type
: Animal Study
Additional Links
Substances
:
Ginseng (Korean)
,
Ginsenosides
Diseases
:
Cardiovascular Diseases
Pharmacological Actions
:
Anti-Platelet
[+]
Ginsenoside Rg5 ameliorates cisplatin-induced nephrotoxicity in mice.
Sep 12, 2016
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Nutrients. 2016 Sep 13 ;8(9). Epub 2016 Sep 13. PMID:
27649238
Article Published Date
: Sep 12, 2016
Study Type
: Animal Study
Additional Links
Substances
:
Ginsenosides
Diseases
:
Chemotherapy-Induced Toxicity: Cisplatin
Pharmacological Actions
:
Anti-Apoptotic
,
Anti-Inflammatory Agents
,
Antioxidants
,
Chemoprotective Agents
[+]
Ginsenoside Rg5 attenuates hepatic glucagon response via suppression of succinate-associated HIF-1α induction in HFD-fed mice.
Mar 08, 2017
Click here to read the entire abstract
Pubmed Data
: Diabetologia. 2017 Mar 9. Epub 2017 Mar 9. PMID:
28280902
Article Published Date
: Mar 08, 2017
Study Type
: Animal Study
Additional Links
Substances
:
Ginsenosides
Diseases
:
High Fat Diet
Pharmacological Actions
:
Antioxidants
,
Hepatoprotective
[+]
Ginsenoside Rg5 exerts a liver protection effect against acetaminophen-induced acute hepatotoxicity.
Oct 24, 2017
Click here to read the entire abstract
Pubmed Data
: J Agric Food Chem. 2017 Oct 25 ;65(42):9226-9236. Epub 2017 Oct 16. PMID:
28965396
Article Published Date
: Oct 24, 2017
Study Type
: Animal Study
Additional Links
Substances
:
Ginsenosides
Diseases
:
Acetaminophen (Tylenol) Toxicity
,
Chemically-Induced Liver Damage
,
Oxidative Stress
Pharmacological Actions
:
Anti-Apoptotic
,
Hepatoprotective
,
Malondialdehyde Down-regulation
Problem Substances
:
Acetaminophen
,
Paracetamol
[+]
Ginsenoside Rg5 has antidepressant activities via the activation of hippocampal BDNF system.
Feb 28, 2017
Click here to read the entire abstract
Pubmed Data
: Neurosci Lett. 2017 Mar 1 ;645:97-105. Epub 2017 Mar 1. PMID:
28257788
Article Published Date
: Feb 28, 2017
Study Type
: Animal Study
Additional Links
Substances
:
Ginsenosides
Diseases
:
Depression
Pharmacological Actions
:
Antidepressive Agents
[+]
Ginsenoside Rg5 overcomes chemotherapeutic multidrug resistance mediated by ABCB1 transporter.
Feb 29, 2020
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: J Ginseng Res. 2020 Mar ;44(2):247-257. Epub 2018 Nov 8. PMID:
32148406
Article Published Date
: Feb 29, 2020
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Ginsenosides
Diseases
:
Cancers: Multi-Drug Resistant
Pharmacological Actions
:
Chemosensitizer
,
Chemotherapeutic
Additional Keywords
:
Chemotherapeutic Synergy: Docetaxel
[+]
Ginsenoside Rg5 prevents cartilage degradation in an osteoarthritis model.
Feb 28, 2017
Click here to read the entire abstract
Pubmed Data
: Oncol Rep. 2017 Mar ;37(3):1497-1502. Epub 2017 Jan 19. PMID:
28112382
Article Published Date
: Feb 28, 2017
Study Type
: Animal Study
Additional Links
Substances
:
Ginsenosides
Diseases
:
Osteoarthritis
Pharmacological Actions
:
Anti-Apoptotic
,
Osteoprotective
[+]
Ginsenoside Rh1 alleviated HK-2 apoptosis in a cisplatin-induced injury model.
Dec 31, 2019
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Evid Based Complement Alternat Med. 2020 ;2020:3401067. Epub 2020 Jul 6. PMID:
32695207
Article Published Date
: Dec 31, 2019
Study Type
: Animal Study
Additional Links
Substances
:
Ginsenosides
Diseases
:
Chemotherapy-Induced Toxicity: Cisplatin
Pharmacological Actions
:
Antioxidants
,
Chemoprotective Agents
[+]
Ginsenoside Rh1 ameliorates high fat diet-induced obesity in mice by inhibiting adipocyte differentiation.
Dec 31, 2012
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Biol Pharm Bull. 2013 ;36(1):102-7. PMID:
23302642
Article Published Date
: Dec 31, 2012
Study Type
: Animal Study
Additional Links
Substances
:
Ginsenosides
Diseases
:
Obesity
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Interleukin-1 beta downregulation
,
Interleukin-6 Downregulation
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
Additional Keywords
:
Anti-Obesity Agents
[+]
Ginsenoside Rh1 inhibits colorectal cancer cell migration and invasion in vitro and tumor growth in vivo.
Sep 30, 2019
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Oncol Lett. 2019 Oct ;18(4):4160-4166. Epub 2019 Aug 14. PMID:
31579419
Article Published Date
: Sep 30, 2019
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Ginsenosides
Diseases
:
Colorectal Cancer
Pharmacological Actions
:
Anti-metastatic
[+]
Ginsenoside Rh1 might be useful in the treatment of sepsis by targeting HMGB1.
Jan 09, 2019
Click here to read the entire abstract
Pubmed Data
: Am J Chin Med. 2019 Jan 10:1-15. Epub 2019 Jan 10. PMID:
30630344
Article Published Date
: Jan 09, 2019
Study Type
: Animal Study
Additional Links
Substances
:
Ginsenosides
Diseases
:
Sepsis
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Interleukin-6 Downregulation
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
Ginsenoside Rh1 prevented cognitive impairment induced by sleep deprivation.
Feb 27, 2017
Click here to read the entire abstract
Pubmed Data
: Phytother Res. 2017 Feb 28. Epub 2017 Feb 28. PMID:
28244162
Article Published Date
: Feb 27, 2017
Study Type
: Animal Study
Additional Links
Substances
:
Ginsenosides
Diseases
:
Memory Disorders
,
Sleep Disorders
Pharmacological Actions
:
Neuroprotective Agents
[+]
Ginsenoside Rh2 ameliorates scopolamine-induced learning deficit in mice.
Sep 30, 2009
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Biol Pharm Bull. 2009 Oct ;32(10):1710-5. PMID:
19801832
Article Published Date
: Sep 30, 2009
Study Type
: Animal Study
Additional Links
Substances
:
Ginsenosides
Diseases
:
Learning disorders
,
Memory Disorders
Pharmacological Actions
:
Neuroprotective Agents
Additional Keywords
:
Phytotherapy
,
Plant Extracts
[+]
Ginsenoside Rh2 can suppress the growth of H22 hepatomas without causing severe side effects.
Apr 30, 2016
Click here to read the entire abstract
Pubmed Data
: Planta Med. 2016 May ;82(8):705-11. Epub 2016 May 10. PMID:
27163230
Article Published Date
: Apr 30, 2016
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Ginseng (Korean)
,
Ginsenosides
Diseases
:
Liver Cancer
Pharmacological Actions
:
Antiproliferative
,
Apoptotic
[+]
Ginsenoside Rh2 enhances the antitumor immunological response of a melanoma mice model
Jan 31, 2017
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Oncol Lett. 2017 Feb ;13(2):681-685. Epub 2016 Dec 12. PMID:
28356946
Article Published Date
: Jan 31, 2017
Study Type
: Animal Study
Additional Links
Substances
:
Ginsenosides
Diseases
:
Melanoma
Pharmacological Actions
:
Immunomodulatory
[+]
Ginsenoside Rh2 G-Rh2 inhibited the proliferation of H1299 cells.
Nov 30, 2017
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Biol Pharm Bull. 2017 Dec 1 ;40(12):2117-2124. Epub 2017 Sep 30. PMID:
28966297
Article Published Date
: Nov 30, 2017
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Ginsenosides
Diseases
:
Lung Cancer
Pharmacological Actions
:
Antiproliferative
,
Apoptotic
[+]
Ginsenoside Rh2 had good anti-tumor effect in vivo.
Jan 31, 2016
Click here to read the entire abstract
Pubmed Data
: Zhongguo Zhong Yao Za Zhi. 2016 Feb ;41(4):700-704. PMID:
28871696
Article Published Date
: Jan 31, 2016
Study Type
: Animal Study
Additional Links
Substances
:
Ginsenosides
Diseases
:
Leukemia: Acute myelogenous leukemia (AML)
Pharmacological Actions
:
Apoptotic
,
Autophagy Up-regulation
Additional Keywords
:
Histone deacetylase inhibitor
[+]
Ginsenoside Rh2 inhibiting HCT116 colon cancer cell proliferation.
Sep 30, 2016
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: J Ginseng Res. 2016 Oct ;40(4):400-408. Epub 2016 Apr 5. PMID:
27746693
Article Published Date
: Sep 30, 2016
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Ginsenosides
Diseases
:
Colon Cancer
Pharmacological Actions
:
Antiproliferative
[+]
Ginsenoside Rh2 is suitable to develop as an alternative remedy for cardiac fibrosis.
Jun 25, 2017
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Int J Mol Sci. 2017 Jun 26 ;18(7). Epub 2017 Jun 26. PMID:
28672855
Article Published Date
: Jun 25, 2017
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Ginsenosides
Diseases
:
Diabetes Mellitus: Type 1
,
Myocardial Fibrosis
Pharmacological Actions
:
Anti-Fibrotic
,
Cardioprotective
[+]
Ginsenoside Rh2 may have efficacy as a dietary supplement for spatial learning and memory improvement.
Jul 31, 2013
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: J Med Food. 2013 Aug ;16(8):772-6. PMID:
23957360
Article Published Date
: Jul 31, 2013
Study Type
: Animal Study
Additional Links
Substances
:
Ginsenosides
Diseases
:
Cognitive Decline/Dysfunction
,
Learning disorders
Pharmacological Actions
:
Neuroprotective Agents
Additional Keywords
:
Plant Extracts
[+]
Ginsenoside Rh2 might serve as a promising candidate compound for Alzheimer's disease.
Aug 03, 2020
Click here to read the entire abstract
Pubmed Data
: Phytother Res. 2020 Aug 4. Epub 2020 Aug 4. PMID:
32754961
Article Published Date
: Aug 03, 2020
Study Type
: Animal Study
Additional Links
Substances
:
Ginsenosides
Diseases
:
Alzheimer's Disease
Pharmacological Actions
:
Neuroprotective Agents
[+]
Ginsenoside Rh2 protects against cisplatin-induced nephrotoxicity via action on caspase-mediated pathway.
Feb 05, 2019
Click here to read the entire abstract
Pubmed Data
: Phytomedicine. 2019 Feb 6 ;61:152862. Epub 2019 Feb 6. PMID:
31048124
Article Published Date
: Feb 05, 2019
Study Type
: Animal Study
Additional Links
Substances
:
Ginsenosides
Diseases
:
Chemotherapy-Induced Toxicity: Cisplatin
Pharmacological Actions
:
Chemoprotective Agents
[+]
Ginsenoside Rh2 reduces ischemic brain injury in rats.
Feb 29, 2004
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Biol Pharm Bull. 2004 Mar ;27(3):433-6. PMID:
14993818
Article Published Date
: Feb 29, 2004
Study Type
: Animal Study
Additional Links
Substances
:
Ginsenosides
Diseases
:
Brain Ischemia
Pharmacological Actions
:
Neuroprotective Agents
Additional Keywords
:
Phytotherapy
[+]
Ginsenoside Rh2 reverses sleep deprivation-induced cognitive deficit in mice.
Mar 11, 2018
Click here to read the entire abstract
Pubmed Data
: Behav Brain Res. 2018 Mar 12. Epub 2018 Mar 12. PMID:
29544964
Article Published Date
: Mar 11, 2018
Study Type
: Animal Study
Additional Links
Substances
:
Ginsenosides
Diseases
:
Cognitive Decline/Dysfunction
,
Sleep Disorders
Pharmacological Actions
:
Neuroprotective Agents
[+]
Ginsenoside Rh3 metabolized from ginsenoside Rg5 may improve chronic dermatitis or psoriasis.
Jul 31, 2006
Click here to read the entire abstract
Pubmed Data
: Arch Pharm Res. 2006 Aug ;29(8):685-90. PMID:
16964764
Article Published Date
: Jul 31, 2006
Study Type
: Animal Study
Additional Links
Substances
:
Ginsenosides
Diseases
:
Dermatitis
,
Psoriasis
Pharmacological Actions
:
Cyclooxygenase 2 Inhibitors
,
Interleukin-1 beta downregulation
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
Ginsenoside Rh4 could be a potentially effective anti-tumor drug for breast cancer.
Mar 30, 2018
Click here to read the entire abstract
Pubmed Data
: Biochem Biophys Res Commun. 2018 Mar 31. Epub 2018 Mar 31. PMID:
29596831
Article Published Date
: Mar 30, 2018
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Ginsenosides
Diseases
:
Breast Cancer
Pharmacological Actions
:
Antiproliferative
,
Apoptotic
,
Cell cycle arrest
[+]
Ginsenoside Rh4 induces apoptosis and autophagic cell death in colorectal cancer cells.
Dec 06, 2017
Click here to read the entire abstract
Pubmed Data
: Biochem Pharmacol. 2017 Dec 7 ;148:64-74. Epub 2017 Dec 7. PMID:
29225132
Article Published Date
: Dec 06, 2017
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Ginsenosides
Diseases
:
Colorectal Cancer
Pharmacological Actions
:
Antiproliferative
,
Apoptotic
,
Autophagy Up-regulation
,
Cell cycle arrest
[+]
Ginsenoside Rk1 ameliorates paracetamol-induced hepatotoxicity.
Dec 31, 2018
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Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: J Ginseng Res. 2019 Jan ;43(1):10-19. Epub 2017 Jul 25. PMID:
