Magnesium

Name	AC	CK
Magnesium Deficiency	62	549
Diabetes Mellitus: Type 2	20	175
Insulin Resistance	13	132
Cardiovascular Diseases	9	104
Hypertension	13	99
Depression	10	93
C-Reactive Protein	8	91
Fibromyalgia	7	70
Metabolic Syndrome X	6	70
Chemotherapy-Induced Toxicity: Cisplatin	8	64
Migraine Disorders	10	64
Diabetes Mellitus: Type 2: Prevention	7	62
Colorectal Cancer: Prevention	3	60
Headache: Migraine	6	52
Obesity	6	51
Osteoporosis	5	50
Inflammation	5	44
Endothelial Dysfunction	4	42
Atrial Fibrillation	5	41
Asthma	4	40
Cardiac Arrhythmias	2	40
Colon Cancer: Prevention	2	40
Coronary Artery Disease	3	40
Postoperative Recovery	2	40
Prediabetes	3	40
Premenstrual syndrome	4	40
Stroke	3	40
Aging	5	32
Vitamin D Deficiency	4	31
Cardiac Mortality	2	30
Colorectal Cancer	2	30
Coronary Bypass Surgery	3	30
Hyperglycemia	2	30
Mitral Valve Prolapse	2	30
Diabetes Mellitus: Type 1	4	23
Attention Deficit Hyperactivity Disorder	2	21
Oxidative Stress	3	21
All-Cause Mortality	2	20
Cardiovascular Disease: Prevention	1	20
Cerebral Aneurysm	2	20
Chemotherapy-Induced Toxicity: Oxaliplatin	1	20
Chronic Disease	1	20
Diabetes: Cardiovascular Illness	2	20
Dyslipidemias	2	20
Gestational Diabetes	2	20
Headache	2	20
Hemodialysis	2	20
Insomnia	2	20
Metabolic Diseases	1	20
Polycystic Ovary Syndrome	2	20
Stroke: Attenuation/Recovery	2	20
Stroke: Hemorrhagic	1	20
Stroke: Ischemic	1	20
Stroke: Prevention	1	20
Testosterone: Too Low	2	20
Tetanus	2	20
Cognitive Decline/Dysfunction	4	15
Hearing Loss	7	15
Congestive Heart Failure	4	13
Arterial Calcification	3	12
Arterial Hardening: Elasticity	2	12
Carotid Stenosis	2	12
Chronic Kidney Disease (CKD)	3	12
Colon Cancer	2	12
Heart Failure	3	12
Triglycerides: Elevated	2	12
Anxiety	2	11
Arrhythmias: Cardiac	2	11
Atherosclerosis	2	11
Autism Spectrum Disorders	2	11
Bone Fractures	2	11
Chronic Obstructive Pulmonary Disease	2	11
Gallstones	2	11
Muscle Damage: Exercise-Induced	2	11
Osteoarthritis	2	11
Pregnancy Complications	2	11
Tachycardia	2	11
ALT: Elevated	1	10
Adrenocorticotropic hormone: Low	1	10
Alcoholic Liver Disease	1	10
Allergic Rhinitis	1	10
Anemia: Sickle Cell	1	10
Aneurysm: Cerebral	1	10
Asthma: Childhood	1	10
Athletic Performance: Recovery	1	10
Atrial Fibrillation: Cardioconversion	1	10
Attention Deficit Disorder with Hyperactivity	1	10
Autism	1	10
Barium Toxicity	1	10
Bladder Stones	1	10
Bruxism	1	10
Burkitt Lymphoma	1	10
Cardiac Surgery	1	10
Celiac Disease	1	10
Cerebral Ischemia	1	10
Cervical Cancer	1	10
Cesarean Section	1	10
Chronic Fatigue Syndrome	1	10
Constipation	1	10
Contraception	1	10
Cortisol: Low	1	10
Cystic Fibrosis	1	10
Depressive Disorder	1	10
Diabetes	1	10
Diabetes: Hypertension	1	10
Diabetic Microangiopathy	1	10
Diabetic Nephropathy	1	10
Diabetic Ulcer	1	10
Epinepherine-induced Disorders	1	10
Epstein-Barr Virus Infections	1	10
Erythromelalgia	1	10
Esophageal Cancer	1	10
Exercise-Induced Hormone Fluctuations	1	10
Facial Tic	1	10
Fatigue	1	10
GGT	1	10
Head Trauma	1	10
Hearing Loss: Noise-Induced	5	10
Hearing Loss: idiopathic, sudden	1	10
Heart Disease	1	10
Hypertension: Arterial	1	10
Hyperuricemia	1	10
Hypothyroidism	1	10
Insulin-Like Growth Factor (IGF): Low	1	10
Kidney Damage	1	10
Kidney Stones	1	10
Left Ventricular Hypertrophy	1	10
Liver Disease	1	10
Low Back Pain	1	10
Lung Cancer	1	10
Menstrual Migraine	1	10
Migraine: Menstrual Cycle Induced	1	10
Migraine: Post-Traumatic	1	10
Mortality: All-Cause	1	10
Muscle Atrophy	1	10
Nonalcoholic fatty liver disease (NAFLD)	1	10
Osteoarthritis: Knee	1	10
Overweight	1	10
Pancreatic Cancer	1	10
Periodontitis	1	10
Pineal Gland Calcification	1	10
Prostate Cancer	1	10
Raynaud Disease	1	10
Results for Liver Enzymes: Elevated AST	1	10
Sarcopenia	1	10
Sleep Apnea: Obstructive	1	10
Subarachnoid hemorrhage	1	10
Surgery: All	1	10
Surgery: Anesthesiology	1	10
Torsades de Pointes	1	10
Wound Healing	1	10
preeclampsia	1	10
Alzheimer's Disease	5	9
Pseudoxanthoma Elasticum	3	6
Vascular Calcification	4	6
Arteriosclerosis	3	4
Aortic Calcification	2	3
Ectopic Calcification	2	3
Hypercholesterolemia	2	3
Multiple Sclerosis	1	3
Muscle Spasm	1	3
Pemphigus: Benign Familial	1	3
Pre-Eclampsia	2	3
Alcohol Toxicity	1	2
Anemia: Hemolytic	1	2
Angina Pectoris	1	2
Arterial Thickening	1	2
Atopic Dermatitis	1	2
Blood-Brain-Barrier Disorders	1	2
Brain Inflammation	1	2
Cardiac Hypertrophy	1	2
Chemotherapy-Induced Toxicity: Vincristine	1	2
Colitis	1	2
Dry Skin	1	2
Feline Hyperthyroidism	1	2
HPA Axis Dysregulation	1	2
Herniated Disc	1	2
Hyperinsulinism	1	2
Hyperlipidemia	1	2
Hypoglycemia	1	2
Hypoxia	1	2
Inflammatory Bowel Diseases	1	2
Intervertebral Disk Displacement	1	2
Intima Media Thickening	1	2
Kidney Failure	1	2
Learning disorders	1	2
Liver Damage	1	2
Low Testosterone	1	2
Memory Disorders	1	2
Mineral Deficiencies	1	2
Neuropathic Pain	1	2
Ovarian Cancer	1	2
Sciatic Nerve Crush Injury	1	2
Spinal Cord Injuries	1	2
Stress	1	2
Thrombosis	1	2
Uremia	1	2
Breast Cancer	1	1
Bronchospasm: Acute	1	1
Calcification: Arterial	1	1
Cancers: All	1	1
Chronic Pain	1	1
Dementia	1	1
Diabetes: Oxidative Stress	1	1
Glaucoma	1	1
Leg Cramps	1	1
Neurological Conditions	1	1
Periodontal Diseases	1	1
Pregnancy-Associated Migraines	1	1
Premature Birth	1	1
Arrhythmias: Drug-Induced	1	0

Name	AC	CK
Antihypertensive Agents	11	124
Hypoglycemic Agents	9	120
Cardioprotective	8	102
Anti-Inflammatory Agents	13	93
Chemoprotective Agents	10	86
Renoprotective	7	62
Insulin Sensitizers	5	60
Antidepressive Agents	6	53
Hypolipidemic	5	52
Chemopreventive	3	41
Antioxidants	5	35
Analgesics	3	31
Neuroprotective Agents	9	24
Anticholesteremic Agents	2	20
Antineoplastic Agents	1	20
Tumor Necrosis Factor (TNF) Alpha Inhibitor	4	16
Hepatoprotective	2	12
Anti-Anxiety Agents	2	11
Hypotensive	2	11
Prophylactic Agents	2	11
Anabolic Agents	1	10
Antiviral Agents	1	10
Bronchodilator Agents	1	10
Osteoprotective	1	10
Secretagogue	1	10
Uricosuric Agents	1	10
Antispasmodic	2	6
NF-kappaB Inhibitor	2	3
Anti-thrombotic	1	2
Antiproliferative	1	2
Gastrointestinal Agents	1	2
Interleukin-1 beta downregulation	1	2
Regenerative	1	2
STAT3 Inhibitor	1	2
Vasodilator Agents	1	2
Anticarcinogenic Agents	1	1
Calcium Channel Blockers	1	1
Chemotherapeutic	1	1
Cytotoxic	1	1

[+]

A higher magnesium intake seems to be associated with a modest reduction in the risk of CRC, in particular, colon cancer.Oct 31, 2012

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Pubmed Data : Eur J Clin Nutr. 2012 Nov ;66(11):1182-6. Epub 2012 Oct 3. PMID: 23031849

Article Published Date : Oct 31, 2012

Study Type : Meta Analysis

Additional Links

Substances : Magnesium

Diseases : Colon Cancer: Prevention, Colorectal Cancer: Prevention

Pharmacological Actions : Chemopreventive

[+]

A higher magnesium intake was associated with lower fasting glucose and insulin.Feb 28, 2013

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Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : J Nutr. 2013 Mar ;143(3):345-53. Epub 2013 Jan 23. PMID: 23343670

Article Published Date : Feb 28, 2013

Study Type : Meta Analysis

Additional Links

Substances : Magnesium

Diseases : Hyperglycemia

Pharmacological Actions : Hypoglycemic Agents

Additional Keywords : Significant Treatment Outcome

[+]

Calcium and magnesium can lessen the incidence of oxaliplatin induced neuropathy.May 31, 2013

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Pubmed Data : J Dig Dis. 2013 Jun ;14(6):288-98. PMID: 23432969

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Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : PLoS One. 2013 ;8(3):e57720. Epub 2013 Mar 8. PMID: 23520480

Article Published Date : Dec 31, 2012

Study Type : Meta Analysis

Additional Links

Substances : Magnesium

Diseases : Cardiovascular Disease: Prevention, Cardiovascular Diseases, Magnesium Deficiency

Pharmacological Actions : Cardioprotective

Additional Keywords : Risk Factors, Risk Reduction

[+]

Dietary magnesium intake was significantly associated with a reduced risk of depression.Feb 28, 2017

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Pubmed Data : Aust N Z J Psychiatry. 2017 Mar ;51(3):219-229. Epub 2016 Nov 2. PMID: 27807012

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Article Publish Status : This is a free article. Click here to read the complete article.

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Pubmed Data : Anesthesiology. 2013 Jul ;119(1):178-90. PMID: 23669270

Article Published Date : Jun 30, 2013

Study Type : Meta Analysis

Additional Links

Substances : Magnesium

Diseases : Postoperative Recovery

Pharmacological Actions : Analgesics

Additional Keywords : Significant Treatment Outcome

[+]

The results suggest that magnesium supplementation is associated with lower waist circumference in obese subjects.Jul 27, 2020

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Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Eur J Clin Nutr. 2014 Apr ;68(4):510-6. Epub 2014 Feb 12. PMID: 24518747

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Medicine (Baltimore). 2017 Mar ;96(11):e6352. PMID: 28296769

Article Published Date : Feb 28, 2017

Study Type : Human Study

Additional Links

Substances : Magnesium

Diseases : Diabetes Mellitus: Type 1, Magnesium Deficiency

Pharmacological Actions : Hypoglycemic Agents

[+]

Daily consumption of 500 mg magnesium oxide tablets leads to improvements in depression status.Feb 28, 2017

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Pubmed Data : Nutrition. 2017 Mar ;35:56-60. Epub 2016 Nov 9. PMID: 28241991

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Pubmed Data : PLoS One. 2015 ;10(11):e0141079. Epub 2015 Nov 4. PMID: 26536119

Article Published Date : Dec 31, 2014

Study Type : Human Study

Additional Links

Substances : Magnesium

Diseases : Hyperuricemia, Magnesium Deficiency

Pharmacological Actions : Uricosuric Agents

Additional Keywords : Risk Factors

[+]

Dietary magnesium may aid conservation of age-related loss of skeletal muscle mass and power in women of all ages.Aug 18, 2015

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Pubmed Data : J Bone Miner Res. 2015 Aug 19. Epub 2015 Aug 19. PMID: 26288012

Article Published Date : Aug 18, 2015

Study Type : Human Study

Additional Links

Substances : Magnesium

Diseases : C-Reactive Protein, Muscle Atrophy

[+]

Dietary magnesium may play a role in musculoskeletal health.Oct 29, 2017

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Pubmed Data : Nutrients. 2017 Oct 30 ;9(11). Epub 2017 Oct 30. PMID: 29084183

Article Published Date : Oct 29, 2017

Study Type : Human Study

Additional Links

Substances : Magnesium

Diseases : Bone Fractures, Osteoporosis, Sarcopenia

Pharmacological Actions : Osteoprotective

[+]

Due to the high hair calcium and magnesium levels in patients with Fibromyalgia supplementation with calcium and magnesium may be beneficial. Nov 01, 1999

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Pubmed Data : J Manipulative Physiol Ther. 1999 Nov-Dec;22(9):586-93. PMID: 10626702

Article Published Date : Nov 01, 1999

Study Type : Human Study

Additional Links

Substances : Calcium, Magnesium

Diseases : Fibromyalgia

[+]

Findings suggest that high magnesium intake alone may improve cognitive function in older adults.May 08, 2020

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Pubmed Data : Eur J Nutr. 2020 May 9. Epub 2020 May 9. PMID: 32388734

Article Published Date : May 08, 2020

Study Type : Human Study

Additional Links

Substances : Magnesium, Vitamin D

Diseases : Aging: Brain , Cognitive Decline/Dysfunction

Pharmacological Actions : Neuroprotective Agents

Additional Keywords : Risk Reduction

[+]

For every 100 mg increase in intake of magnesium a 49% reduction in the risk for mortality due to liver diseases was found. Dec 19, 2017

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Higher dietary magnesium intake is associated with lower body mass index, waist circumference and serum glucose in Mexican adults.Jan 04, 2018

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Pubmed Data : Nutr J. 2018 12 5 ;17(1):114. Epub 2018 Dec 5. PMID: 30518394

Article Published Date : Jan 04, 2018

Study Type : Human Study

Additional Links

Substances : Magnesium

Diseases : Magnesium Deficiency, Obesity

Additional Keywords : Anti-Obesity Agents, Risk Reduction

[+]

Higher magnesium intake is independently associated with better insulin sensitivity in patients at risk for type 2 diabetes mellitus.Dec 31, 2016

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Pubmed Data : Diabetologia. 2017 May ;60(5):843-853. Epub 2017 Feb 21. PMID: 28224192

Article Published Date : Apr 30, 2017

Study Type : Human Study

Additional Links

Substances : Magnesium

Diseases : Insulin Resistance, Magnesium Deficiency, Prediabetes

Additional Keywords : Increased Risk, Risk Reduction

[+]

Low serum magnesium levels at admission were found to be associated with the presence of post-stroke depression at 3 months after stroke.Nov 30, 2016

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Pubmed Data : Aging Dis. 2016 Dec ;7(6):687-690. Epub 2016 Dec 1. PMID: 28053818

Article Published Date : Nov 30, 2016

Study Type : Human Study

Additional Links

Substances : Magnesium

Diseases : Depression, Magnesium Deficiency, Stroke: Attenuation/Recovery

Additional Keywords : Risk Factors

[+]

Low serum magnesium may be included in pathogenesis of poor glycemic control and abnormal lipid profile in children with type 1 diabetes.Oct 31, 2016

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Pubmed Data : Osteoarthritis Cartilage. 2018 Feb 15. Epub 2018 Feb 15. PMID: 29454594

Article Published Date : Feb 14, 2018

Study Type : Human Study

Additional Links

Substances : Magnesium

Diseases : Magnesium Deficiency, Osteoarthritis: Knee

Additional Keywords : Risk Factors

[+]

Lower serum magnesium levels are associated with coronary artery calcification in Mexican subjects.Dec 31, 2015

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Pubmed Data : Nutr J. 2016 ;15(1):22. Epub 2016 Mar 1. PMID: 26931571

Article Published Date : Dec 31, 2015

Study Type : Human Study

Additional Links

Substances : Magnesium

Diseases : Atherosclerosis, Diabetes Mellitus: Type 2: Prevention, Hypertension, Magnesium Deficiency

Additional Keywords : Risk Factors, Risk Reduction

[+]

Lower serum Mg level may be conducive to the development of total testosterone deficiency, arterial hypertension, diabetes, and therefore metabolic syndrome.Jul 31, 2015

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Pubmed Data : Magnes Res. 2015 Aug 1 ;28(3):99-107. PMID: 26507751

Pubmed Data : Biol Trace Elem Res. 2017 Nov 10. Epub 2017 Nov 10. PMID: 29127547

Article Published Date : Nov 09, 2017

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Pubmed Data : Neurosurgery. 2003 Feb;52(2):276-81; discussion 281-2. PMID: 12535355

Article Published Date : Feb 01, 2003

Study Type : Human Study

Additional Links

Substances : Magnesium

Diseases : Cerebral Aneurysm, Cerebral Ischemia, Magnesium Deficiency, Subarachnoid hemorrhage

[+]

Magnesium deficiency is associated with increased risk of diabetic retinopathy and poor glycemic control.Apr 30, 2019

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Pubmed Data : J Family Med Prim Care. 2019 May ;8(5):1671-1677. PMID: 31198735

Article Published Date : Apr 30, 2019

Additional Keywords : Drug-Plant-Vitamin Synergies

[+]

Magnesium sulphate reduces intraoperative anaesthetic requirements and improves the quality of postoperative analgesia.Mar 01, 2008

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Pubmed Data : Br J Anaesth. 2008 Mar;100(3):397-403. PMID: 18276652

Pubmed Data : Eur J Clin Nutr. 2007 Jan;61(1):54-60. Epub 2006 Jun 21. PMID: 16788707

Article Published Date : Jan 01, 2007

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Pubmed Data : Appl Physiol Nutr Metab. 2018 Jan 9. Epub 2018 Jan 9. PMID: 29316405

Article Published Date : Jan 08, 2018

Study Type : Human Study

Additional Links

Substances : Calcium, Magnesium, Vitamin D, Zinc

Diseases : Gestational Diabetes

Pharmacological Actions : Cardioprotective, Hypoglycemic Agents

[+]

Magnesium-zinc-calcium-vitamin D supplementation in patients with PCOS had beneficial effects on insulin metabolism and markers of cardio-metabolic risk.Sep 30, 2017

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Pubmed Data : Arch Iran Med. 2017 Oct ;20(10):640-645. PMID: 29137465

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Pubmed Data : Eur J Appl Physiol. 2019 Oct 17. Epub 2019 Oct 17. PMID: 31624951

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Pubmed Data : Cardiovasc Toxicol. 2008;8(3):115-25. Epub 2008 Jul 8. PMID: 16978367

Article Published Date : Jan 01, 2008

Study Type : Human Study

Additional Links

Substances : Magnesium

Diseases : Diabetes: Cardiovascular Illness, Diabetes Mellitus: Type 2

[+]

Oral magnesium supplementation improves insulin sensitivity and metabolic control in type 2 diabetic subjects. Apr 01, 2003

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Pubmed Data : Diabetes Care. 2003 Apr;26(4):1147-52. PMID: 12663588

Article Published Date : Apr 01, 2003

Study Type : Human Study

Additional Links

Substances : Magnesium

Diseases : Diabetes Mellitus: Type 2, Insulin Resistance

Pharmacological Actions : Hypoglycemic Agents

[+]

Oral magnesium supplementation improves the metabolic profile and blood pressure of MONW individuals.Jun 30, 2014

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Pubmed Data : Arch Med Res. 2014 Jul ;45(5):388-93. Epub 2014 May 13. PMID: 24830937

Article Published Date : Jun 30, 2014

Study Type : Human Study

Additional Links

Substances : Magnesium

Diseases : Hypertension, Magnesium Deficiency, Metabolic Syndrome X, Obesity, Triglycerides: Elevated

Pharmacological Actions : Anticholesteremic Agents, Antihypertensive Agents

Additional Keywords : Significant Treatment Outcome , Supplementation

[+]

Pubmed Data : J Alzheimers Dis. 2015 Oct 27 ;49(4):971-90. PMID: 26519439

Article Published Date : Oct 26, 2015

Study Type : Human Study

Additional Links

Substances : Magnesium

Diseases : Cognitive Decline/Dysfunction

Pharmacological Actions : Neuroprotective Agents

Additional Keywords : Significant Treatment Outcome

[+]

The health consequences of suboptimal magnesium status in the United States are underestimated.Mar 01, 2012

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Pubmed Data : Nutr Rev. 2012 Mar ;70(3):153-64. Epub 2012 Feb 15. PMID: 22364157

Article Published Date : Mar 01, 2012

Study Type : Human Study

Additional Links

Substances : Magnesium

Diseases : C-Reactive Protein, Diabetes Mellitus: Type 2, Magnesium Deficiency

[+]

The metabolic correction program implemented resulted in significant reductions in glucose, triglycerides, cholesterol, weight and waist circumference.Mar 31, 2015

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Pubmed Data : Bol Asoc Med P R. 2015 Apr-Jun;107(2):54-9. PMID: 26434085

Pubmed Data : Turk J Pediatr. 2009 May-Jun;51(3):220-4. PMID: 16567569

Article Published Date : May 01, 2009

Study Type : Human Study

Additional Links

Substances : Magnesium

Diseases : Metabolic Syndrome X

[+]

The human"magnesome": detecting magnesium binding sites on human proteins.Dec 31, 2011

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Pubmed Data : BMC Bioinformatics. 2012 ;13 Suppl 14:S10. Epub 2012 Sep 7. PMID: 23095498

Article Published Date : Dec 31, 2011

Study Type : Human In Vitro

Additional Links

Substances : Magnesium

Diseases : Magnesium Deficiency

[+]

A child with Connexin 26 related hearing loss who experienced 7 years of progressive hearing loss and was ameliorated by ACEMg supplementation.Feb 28, 2014

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Pubmed Data : Int J Pediatr Otorhinolaryngol. 2014 Mar ;78(3):563-5. Epub 2014 Jan 3. PMID: 24439969

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Pubmed Data : Neuron. 2010 Jan 28 ;65(2):165-77. PMID: 20152124

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Pubmed Data : Eur J Pharmacol. 2002 May 10;442(3):241-50. PMID: 12065078

Article Published Date : May 10, 2002

Study Type : Animal Study

Additional Links

Substances : Magnesium

Diseases : Alcohol Toxicity , Endothelial Dysfunction

[+]

Dietary magnesium supplementation prevents and reverses vascular and soft tissue calcifications.Oct 31, 2017

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Pubmed Data : Kidney Int. 2017 Nov ;92(5):1084-1099. Epub 2017 Jul 29. PMID: 28760336

Article Published Date : Oct 31, 2017

Study Type : Animal Study

Additional Links

Substances : Magnesium

Diseases : Vascular Calcification

Pharmacological Actions : Anti-Inflammatory Agents, NF-kappaB Inhibitor, Tumor Necrosis Factor (TNF) Alpha Inhibitor

[+]

Dietary supplementation with a magnesium-rich marine mineral blend enhances the diversity of gastrointestinal microbiota.Jun 19, 2018

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Pubmed Data : Biomaterials. 2020 Jan 31 ;238:119828. Epub 2020 Jan 31. PMID: 32045781

Article Published Date : Jan 30, 2020

Study Type : Animal Study

Additional Links

Substances : Magnesium, Vitamin C

Diseases : Osteonecrosis, Steroid-Induced Toxicity

Pharmacological Actions : Angiogenesis Inducing Agents, Anti-Inflammatory Agents

[+]

Magnesium boosts the memory restorative effect of environmental enrichment in Alzheimer's disease mice.Dec 31, 2017

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Pubmed Data : CNS Neurosci Ther. 2018 Jan ;24(1):70-79. Epub 2017 Nov 10. PMID: 29125684

Pubmed Data : Am J Physiol Renal Physiol. 2017 Aug 1 ;313(2):F339-F350. Epub 2017 Apr 19. PMID: 28424213

Article Published Date : Jul 31, 2017

Study Type : Animal Study

Additional Links

Substances : Magnesium

Diseases : Chemotherapy-Induced Toxicity: Cisplatin, Colon Cancer, Magnesium Deficiency

Pharmacological Actions : Antiproliferative , Chemoprotective Agents

Additional Keywords : Chemotherapeutic Synergy: Cisplatin

[+]

Magnesium inhibits the binding of testosterone (TT) to sex hormone-binding globulin (SHBG) leading to an enhancement of bioavailable TT.Feb 20, 2009

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Pubmed Data : J Pharm Biomed Anal. 2009 Feb 20;49(2):175-80. Epub 2008 Nov 5. PMID: 19095394

Article Published Date : Feb 20, 2009

Study Type : Animal Study

Additional Links

Substances : Magnesium

Diseases : Low Testosterone

[+]

Magnesium L-threonate was able to prevent and restore the short-term memory deficits in an animal model of chronic neuropathic pain.Aug 31, 2013

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Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Pain Physician. 2013 Sep-Oct;16(5):E563-75. PMID: 24077207

Article Published Date : Aug 31, 2013

Study Type : Animal Study

Additional Links

Substances : Magnesium

Diseases : Memory Disorders, Neuropathic Pain

Pharmacological Actions : Tumor Necrosis Factor (TNF) Alpha Inhibitor

[+]

Magnesium-L-threonate may have therapeutic value for treating pain and comorbid depression or memory deficits in bladder pain syndrome/interstitial cystitis.Apr 01, 2020

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Pubmed Data : Life Sci. 2021 Feb 22 ;272:119257. Epub 2021 Feb 22. PMID: 33631176

Article Published Date : Feb 21, 2021

Study Type : Animal Study

Additional Links

Substances : Magnesium

Diseases : Cerebral Ischemia

Pharmacological Actions : Neuroprotective Agents

[+]

Oral administration of magnesium-L-threonate reduces neuroinflammation.Nov 08, 2015

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Pubmed Data : Cell Mol Immunol. 2015 Nov 9. Epub 2015 Nov 9. PMID: 26549801

Article Published Date : Nov 08, 2015

Study Type : In Vitro Study, Transgenic Animal Study

Additional Links

Substances : Magnesium

Diseases : Alzheimer's Disease, Brain Inflammation

Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-1 beta downregulation

Additional Keywords : Supplementation

[+]

Oral application of magnesium-L-threonate attenuates vincristine-induced allodynia and hyperalgesia.Mar 16, 2017

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Pubmed Data : Anesthesiology. 2017 Mar 17. Epub 2017 Mar 17. PMID: 28306698

Pubmed Data : Magnes Res. 2016 Mar 1 ;29(3):112-119. PMID: 27910808

Article Published Date : Feb 29, 2016

Study Type : Animal Study

Additional Links

Substances : Magnesium

Diseases : Depression, Magnesium Deficiency

Pharmacological Actions : Antidepressive Agents

Problem Substances : Antidepressants

[+]

Severe magnesium deficiency compromises systemic bone mineral density and aggravates inflammatory bone resorption.Nov 25, 2019

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Pubmed Data : J Nutr Biochem. 2019 Nov 26 ;77:108301. Epub 2019 Nov 26. PMID: 31825817

Article Published Date : Nov 25, 2019

Study Type : Animal Study

Additional Links

Substances : Magnesium

Diseases : Magnesium Deficiency, Osteoporosis, Periodontal Diseases

Additional Keywords : Increased Risk

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Synergistic effects of magnesium ions and simvastatin on attenuation of high-fat diet-induced bone loss.Jul 31, 2021

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Pubmed Data : Bioact Mater. 2021 Aug ;6(8):2511-2522. Epub 2021 Feb 3. PMID: 33665494

Article Published Date : Jul 31, 2021

Study Type : Animal Study

Additional Links

Substances : Magnesium

Diseases : Hyperlipidemia

Pharmacological Actions : Osteoprotective

Additional Keywords : Natural Substance/Drug Synergy

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The severity of feline hyperthyroidism may contribute to a decrease in the ionized magnesium concentration.Apr 01, 2006

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Pubmed Data : Can J Vet Res. 2006 Apr;70(2):137-42. PMID: 16639946

Article Published Date : Apr 01, 2006

Study Type : Animal Study

Additional Links

Substances : Magnesium

Diseases : Feline Hyperthyroidism

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These findings demonstrate the renoprotective role of magnesium during cisplatin acute kidney injury without compromising the chemotherapeutic efficacy of cisplatin.May 05, 2015

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Pubmed Data : Am J Physiol Renal Physiol. 2015 May 6:ajprenal.00096.2015. Epub 2015 May 6. PMID: 25947343

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : J Am Coll Nutr. 2020 Jul 10:1-9. Epub 2020 Jul 10. PMID: 32649272

Article Published Date : Jul 09, 2020

Study Type : Review

Additional Links

Substances : Magnesium

Diseases : Coronavirus Infection

Pharmacological Actions : Anti-Inflammatory Agents, Immunomodulatory, Interleukin-6 Downregulation

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Consuming a healthy diet that provides the recommended amount of magnesium can be an appropriate strategy for helping control blood pressure.Jun 10, 2018

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Pubmed Data : Int J Mol Sci. 2018 Jun 11 ;19(6). Epub 2018 Jun 11. PMID: 29891771

Pubmed Data : J Cell Physiol. 2016 Jan 11. Epub 2016 Jan 11. PMID: 26754806

Article Published Date : Jan 10, 2016

Study Type : In Vitro Study

Additional Links

Substances : Magnesium

Diseases : Cognitive Decline/Dysfunction

Pharmacological Actions : Neuroprotective Agents

Additional Keywords : Neural Stem Cells

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Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Rocz Panstw Zakl Hig. 2013 ;64(3):165-71. PMID: 24325082

Article Published Date : Dec 31, 2012

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Pubmed Data : Iran J Public Health. 2019 Mar ;48(3):379-387. PMID: 31223564

Article Published Date : Feb 28, 2019

Study Type : Review

Additional Links

Substances : Magnesium

Diseases : Alzheimer's Disease, Cerebral Vasospasm, Headache: Migraine, Parkinson's Disease, Stroke

Pharmacological Actions : Neuroprotective Agents

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Magnesium has effects that parallel those of statins. Oct 23, 2004

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Pubmed Data : 2004 Oct. Epub 2004 Oct. PMID: 15466951

Article Published Date : Oct 23, 2004

Pubmed Data : J Am Coll Nutr. 2004 Oct;23(5):501S-505S. PMID: 15466951

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Nutrients. 2017 Aug 28 ;9(9). Epub 2017 Aug 28. PMID: 28846654

Article Published Date : Aug 27, 2017

Study Type : Review

Additional Links

Substances : Magnesium

Diseases : Muscle Damage: Exercise-Induced

Therapeutic Actions : Exercise

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Magnesium to counteract elastin degradation and vascular calcification in chronic obstructive pulmonary disease.Aug 31, 2017

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Pubmed Data : Med Hypotheses. 2017 Sep ;107:74-77. Epub 2017 Aug 12. PMID: 28915968

Article Published Date : Aug 31, 2017

Study Type : Review

Additional Links

Substances : Magnesium

Diseases : Chronic Obstructive Pulmonary Disease, Vascular Calcification

[+]

Nutritional supplementation for the prevention and the treatment of gestational diabetes mellitus.Jul 31, 2019

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Pubmed Data : Curr Diab Rep. 2019 Aug 1 ;19(9):73. Epub 2019 Aug 1. PMID: 31368026

Article Published Date : Jul 31, 2019

Study Type : Review

Additional Links

Substances : Magnesium, Myo-inositol, Probiotics, Selenium, Vitamin B-6, Vitamin D, Zinc

Diseases : Gestational Diabetes

Additional Keywords : Risk Reduction

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A higher magnesium intake seems to be associated with a modest reduction in the risk of CRC, in particular, colon cancer.Oct 31, 2012

A higher magnesium intake was associated with lower fasting glucose and insulin.Feb 28, 2013

Calcium and magnesium can lessen the incidence of oxaliplatin induced neuropathy.May 31, 2013

Cardiovascular risks are significantly lower in individuals who excrete higher levels of magnesium and taurine, indicating their protective roles.Jan 01, 2010

Circulating and dietary magnesium levels are inversely associated with cardiovascular disease risk.Jun 30, 2013

Dietary magnesium intake and serum magnesium concentrations are inversely associated with the risk of total CVD events.Dec 31, 2012

Dietary magnesium intake was significantly associated with a reduced risk of depression.Feb 28, 2017

High intakes of magnesium and potassium but not calcium were also significantly associated with reduced risk of stroke in women.May 05, 2015

Higher dietary magnesium intake seems to have a protective effect for cancer, especially colorectal cancer and in females.Dec 31, 2013

Intravenous and oral magnesium should be adapted as parts of multimodal approach to reduce migraine.Dec 31, 2015

Low serum level of magnesium seems to be a risk factor for osteoporosis among the postmenopausal women.May 31, 2014

Magnesium intake reduces colorectal tumor riskAug 31, 2012

Magnesium orotate is promising not only in treating MVP and compensating for hypomagnesemia, but also in preventing and treating cardiac arrhythmias.Dec 31, 2014

Magnesium supplementation appears to have a beneficial role and improves glucose parameters in people with diabetes.Aug 16, 2016

Magnesium supplementation may decrease the risk T2D associated cardiovascular diseases.Feb 01, 2017

Magnesium supplementation may improve endothelial function without affecting carotid intima media thickness.Apr 13, 2018

Magnesium supplementation may reduce the incidence of postoperative arrhythmias in pediatric patients undergoing cardiopulmonary bypass.Jul 31, 2013

Magnesium supplementation significantly lowers BP in individuals with insulin resistance, prediabetes, or other noncommunicable chronic diseases.Aug 31, 2017

Proton pump inhibitor use may increase the risk of hypomagnesemia.Dec 31, 2013

Serum magnesium levels are inversely associated with risk of coronary artery disease.May 16, 2018

The combined data supports a role for magnesium in reducing risk of type 2 diabetes mellitus.Nov 18, 2016

The evidence from this meta-analysis supports the theory that an inverse relationship between serum magnesium deficiency and ADHD exists.Feb 18, 2019

The present meta-analysis of prospective cohorts suggests that higher magnesium intake is associated with reduced risk of total and ischaemic stroke.Jul 09, 2012

The present meta-analysis suggests that dietary magnesium intake is inversely associated with the prevalence of metabolic syndrome.Oct 31, 2014

The reduction in both pain and morphine use indicates magnesium has some utility as an analgesic adjunct after surgery.Jun 30, 2013

The results suggest that magnesium supplementation is associated with lower waist circumference in obese subjects.Jul 27, 2020

These results highlight the potential protective effect of magnesium supplementation on cisplatin-induced acute nephrotoxicity.Aug 18, 2019

This finding suggests that magnesium supplements may have a beneficial role as an adjuvant for the management of low-grade chronic systemic inflammation.Dec 31, 2016

This meta-analysis and systematic review indicates that dietary magnesium intake is significantly and inversely associated with serum CRP levels.Mar 31, 2014

This study found a significant reduction in body mass index following magnesium supplementation.Jul 10, 2020

This uniform subset of seven studies showed a strong effect of magnesium treatment in hypertension, which is in stark contrast to results of three other meta-analyses. Jun 30, 2013

"Lower intake of magnesium and dietary fiber increases the incidence of type 2 diabetes in Taiwanese."Oct 31, 2012

A combination of malic acid and magnesium is safe and may be beneficial in the treatment of patients with fibromyalgia. May 01, 1995

A combination of omega-3 and omega-6 fatty acids as well as magnesium and zinc consumption on attentional, behavioural, and emotional problems of children and adolescents.Jan 01, 2010

A combination of probiotics and magnesium orotate attenuate depression.Mar 31, 2017

A diet rich in magnesium, potassium, and calcium may contribute to reduced risk of stroke among men. Sep 30, 2015

A short hydration regimen with 20 mEq of magnesium supplementation is safe and feasible for patients with lung cancer receiving cisplatin-based chemotherapy.Jul 31, 2020

A short hydration regimen with magnesium supplementation prevents cisplatin-induced nephrotoxicityDec 12, 2016

A single-loading dose of intravenous magnesium improved insulin resistance indices in critically ill patients with stress-induced hyperglycemia.Dec 31, 2017

After 3 months of treatment with the supplement, a reduction of migraine pain and burden of disease was seen.Dec 31, 2014

An intravenous hydration regimen supplemented with magnesium prevented cisplatin-induced nephrotoxicity in patients with head and neck cancer.Feb 01, 2018

calcium, magnesium, and zinc supplements have a significant effect on the prevention of preeclampsia.Apr 30, 2017

Children with autistic spectrum disorders require special dietary management due to their lower plasma concentration of magnesium. Jan 01, 2008

COPD is accompanied by a lowered magnesium level and an alteration in antioxidant status due to possible oxidative stress in this disease.Dec 31, 2000

Correction of hypomagnesemia in type 1 diabetic children with oral magnesium supplements is associated with optimization of glycemic control.Feb 28, 2017

Daily consumption of 500 mg magnesium oxide tablets leads to improvements in depression status.Feb 28, 2017

Daily magnesium supplement of 350 mg for 24 wk in overweight and obese adults reduces arterial stiffness.Apr 30, 2016

Dietary intake of taurine and magnesium may prolong lifespan by preventing the progression of cardiovascular diseases.Nov 30, 2016

Dietary magnesium intake is inversely associated with hyperuricemia.Dec 31, 2014

Dietary magnesium may aid conservation of age-related loss of skeletal muscle mass and power in women of all ages.Aug 18, 2015

Dietary magnesium may play a role in musculoskeletal health.Oct 29, 2017

Due to the high hair calcium and magnesium levels in patients with Fibromyalgia supplementation with calcium and magnesium may be beneficial. Nov 01, 1999

Findings suggest that high magnesium intake alone may improve cognitive function in older adults.May 08, 2020

For every 100 mg increase in intake of magnesium a 49% reduction in the risk for mortality due to liver diseases was found. Dec 19, 2017

Ginkgo biloba extract with arginine and magnesium can improve the dynamics of cutaneous trophism in lesions caused by diabetic and non-diabetic microangiopathy.Jun 01, 1999

High dietary intake of seaweed, calcium, magnesium, and phosphorus may be associated with a decreased prevalence of allergic rhinitis.Aug 01, 2006

High dose magnesium converts ibutilide into a safer and more effective agent.Sep 01, 2010

High dose magnesium may be beneficial in the treatment of chronic, intractable erythromelalgia. Feb 01, 2002

High dose magnesium may improve control and/or prevent complications in type 2 diabetic patients. May 01, 1998

High intake of magnesium may be associated with reduced risks of fatty liver disease and prediabetes.Apr 01, 2018

High-volume hydration and magnesium supplementation can reduce the renal toxicity induced by cisplatin.Dec 31, 2013

Higher dietary intake of magnesium, calcium, iron, and zinc is associated with lower prevalence of depressive symptoms in Japanese employees.Apr 30, 2015

Higher dietary magnesium intake and higher magnesium status are associated with lower prevalence of coronary heart disease in patients with type 2 diabetes.Mar 04, 2018

Higher dietary magnesium intake is associated with lower body mass index, waist circumference and serum glucose in Mexican adults.Jan 04, 2018

Higher magnesium intake is independently associated with better insulin sensitivity in patients at risk for type 2 diabetes mellitus.Dec 31, 2016

Higher serum magnesium level may be associated with better endothelial function in end stage renal disease patients on hemodialysis.Oct 31, 2016

Hypomagnesaemia was significantly associated with higher prevalence of diabetic nephropathy.Jul 13, 2016

Hypomagnesemia is frequently present in patients with diabetes mellitus and it appears that its prevalence increases with the duration of diabetes mellitus.Mar 31, 2019

Impaired glucose tolerance and dyslipidaemia associated with OC use may be prevented by increased dietary magnesium.Jun 01, 2008

Improvement of pain and impairment in complex regional pain syndrome with intravenous magnesium sulfate.Jul 01, 2009

In this cohort of middle-aged and older men low serum 25(OH)D3 concentration was associated with increased risk of death mainly in those with lower magnesium intake. Mar 31, 2015

Intake of potassium- and magnesium-enriched salt improves functional outcome after strokeSep 05, 2017

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View the Evidence:
317 Abstracts with Magnesium Research