Phenethyl isothiocyanate

Views 737
Jump to
Abstracts Focused Research Topics
Your Token Count0

Sign in to Purchase/Download Documents

Sign in / Register

Focus Your Research

Click any topic below to filter + focus research
8 Diseases Researched for Phenethyl isothiocyanate
NameACCKFocus
Prostate Cancer35Locked
Inflammation22Locked
Lung Cancer12Locked
Nicotine/Tobacco Toxicity 12Locked
Smoking12Locked
Lipopolysaccharide-Induced Toxicity11Locked
Ovarian Cancer11Locked
Oxidative Stress11Locked
13 Pharmacological Actions Researched for Phenethyl isothiocyanate
NameACCKFocus
Anticarcinogenic Agents58Locked
Antiproliferative 35Locked
Apoptotic35Locked
Antineoplastic Agents23Locked
Anti-Inflammatory Agents11Locked
Anti-metastatic11Locked
Antioxidants11Locked
Chemopreventive11Locked
Cyclooxygenase 2 Inhibitors11Locked
MicroRNA modulator11Locked
NF-kappaB Inhibitor11Locked
Nrf2 activation11Locked
Tumor Necrosis Factor (TNF) Alpha Inhibitor11Locked
Related Topics

Phenethyl isothiocyanate is a Sub of the following Topic

View the Evidence:
35 Abstracts with Phenethyl isothiocyanate Research

[+]

Curcumin and phenethyl isothiocyanate have a synergistic inhibitory effect on the growth of human prostate xenografts. Jul 01, 2008

Pubmed Data : Am J Clin Nutr. 2008 Jul;88(1):216-23. PMID: 16423986
Article Published Date : Jul 01, 2008
Study Type : Animal Study
Additional Links
Substances : Curcumin, Phenethyl isothiocyanate
Diseases : Prostate Cancer
Pharmacological Actions : Anticarcinogenic Agents, Antineoplastic Agents, Antiproliferative , Apoptotic
Additional Keywords : Isothiocyanates, Natural Substance Synergy
[+]

Curcumin and phenyethylisothiocyanate inhibite mouse prostate cancer. Sep 01, 2008

Pubmed Data : Pharm Res. 2008 Sep;25(9):2181-9. Epub 2008 Apr 25. PMID: 18437538
Article Published Date : Sep 01, 2008
Study Type : Animal Study
Additional Links
Substances : Curcumin, Phenethyl isothiocyanate
Diseases : Prostate Cancer
Pharmacological Actions : Anticarcinogenic Agents, Antiproliferative , Apoptotic
Additional Keywords : Isothiocyanates
[+]

Phenethyl isothiocyanate and sulforaphane and their N-acetylcysteine conjugates inhibit malignant progression of lung adenomas induced by tobacco carcinogens in A/J mice.Sep 15, 2005

Pubmed Data : Cancer Res. 2005 Sep 15;65(18):8548-57. PMID: 16166336
Article Published Date : Sep 15, 2005
Study Type : Animal Study
Additional Links
Substances : NAC (N-acetyl-L-cysteine), Phenethyl isothiocyanate, Sulforaphane
Diseases : Lung Cancer, Nicotine/Tobacco Toxicity , Smoking
Pharmacological Actions : Anticarcinogenic Agents
Additional Keywords : Isothiocyanates
[+]

Phenethyl isothiocyanate hampers growth and progression of HER2-positive breast and ovarian carcinoma by targeting their stem cell compartment.Aug 01, 2019

Pubmed Data : Cell Oncol (Dordr). 2019 Aug 2. Epub 2019 Aug 2. PMID: 31376137
Article Published Date : Aug 01, 2019
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Phenethyl isothiocyanate
Diseases : Breast Cancer, Ovarian Cancer
Pharmacological Actions : Antiproliferative
Additional Keywords : Cancer Stem Cells, Natural Substance/Drug Synergy
[+]

Phenethyl isothiocyanate inhibits in vivo growth of xenograft tumors of human glioblastoma cells.Sep 09, 2018

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Molecules. 2018 Sep 10 ;23(9). Epub 2018 Sep 10. PMID: 30201893
Article Published Date : Sep 09, 2018
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Phenethyl isothiocyanate
Diseases : Glioblastoma
Pharmacological Actions : Antiproliferative
[+]

Phenethyl isothiocyanate may act as a promising anticancer agent either alone or in combination with doxorubicin through apoptotic cell death induction.Dec 31, 2017

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Iran J Pharm Res. 2018 ;17(4):1328-1338. PMID: 30568691
Article Published Date : Dec 31, 2017
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Phenethyl isothiocyanate
Diseases : Ehrlich carcinoma
Pharmacological Actions : Antiproliferative , Apoptotic, Chemosensitizer
Additional Keywords : Chemotherapeutic Synergy: Doxorubicin
[+]

Phenethyl isothiocyanate treatment suppressed the proliferation of ALDH1 expressing cancer stem cells.Feb 26, 2019

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Int J Mol Sci. 2019 Feb 27 ;20(5). Epub 2019 Feb 27. PMID: 30818757
Article Published Date : Feb 26, 2019
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Phenethyl isothiocyanate
Diseases : Cancers: All
Pharmacological Actions : Antiproliferative
Additional Keywords : Cancer Stem Cells
[+]

Reactivation of mutant p53 by a dietary-related compound phenethyl isothiocyanate inhibits tumor growth.Jan 09, 2016

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Cell Death Differ. 2016 10 ;23(10):1615-27. Epub 2016 Jun 3. PMID: 27258787
Article Published Date : Jan 09, 2016
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Phenethyl isothiocyanate
Diseases : Cancers: All
Pharmacological Actions : Tumor Suppressor Protein p53 Upregulation
[+]

These findings indicate that benzyl isothiocyanate and phenethyl isothiocyanate ameliorate high fat diet-induced obesity and fatty liver.Jun 25, 2019

Pubmed Data : J Agric Food Chem. 2019 Jun 26 ;67(25):7136-7146. Epub 2019 Jun 18. PMID: 31240929
Article Published Date : Jun 25, 2019
Study Type : Animal Study
Additional Links
Substances : Benzyl isothiocyanate , Phenethyl isothiocyanate
Diseases : Fatty Liver, Obesity
Pharmacological Actions : Hepatoprotective
Additional Keywords : Anti-Obesity Agents
[+]

A combination of phenethyl isothiocyanate and TH588 has potential as a novel therapeutic strategy against pancreatic cancer.Feb 28, 2018

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Oncol Lett. 2018 Mar ;15(3):3240-3244. Epub 2017 Dec 29. PMID: 29435064
Article Published Date : Feb 28, 2018
Study Type : In Vitro Study
Additional Links
Substances : Phenethyl isothiocyanate
Diseases : Pancreatic Cancer
Pharmacological Actions : Antiproliferative , Chemotherapeutic
[+]

A review of the role of phytochemicals in cancer prevention.Oct 08, 2019

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Int J Mol Sci. 2019 Oct 9 ;20(20). Epub 2019 Oct 9. PMID: 31600949
Article Published Date : Oct 08, 2019
Study Type : Review
Additional Links
Substances : Benzyl isothiocyanate , Capsaicin, Catechin , Cucurbitacin B , Isoflavones, Lycopene, Phenethyl isothiocyanate, Piperlongumine
Diseases : Cancers: All
Pharmacological Actions : Anticarcinogenic Agents
[+]

Benzyl isothiocyanate and phenethyl isothiocyanate inhibit murine melanoma B16F10 cell migration and invasion.Aug 31, 2017

Pubmed Data : Int J Oncol. 2017 Sep ;51(3):832-840. Epub 2017 Jul 27. PMID: 28766686
Article Published Date : Aug 31, 2017
Study Type : In Vitro Study
Additional Links
Substances : Benzyl isothiocyanate , Phenethyl isothiocyanate
Diseases : Cancer Metastasis, Melanoma
Pharmacological Actions : Anti-metastatic, Antiproliferative , Matrix metalloproteinase-2 (MMP-2) inhibitor
Additional Keywords : Isothiocyanates
[+]

benzyl isothiocyanate can be considered as a promising candidate in cancer chemoprevention. Jun 30, 2016

Pubmed Data : Vojnosanit Pregl. 2016 Jul ;73(7):636-42. PMID: 29314795
Article Published Date : Jun 30, 2016
Study Type : In Vitro Study
Additional Links
Substances : Benzyl isothiocyanate , Phenethyl isothiocyanate, Sulforaphane
Diseases : Cancers: All
Pharmacological Actions : Anticarcinogenic Agents, Antiproliferative , Chemopreventive
Additional Keywords : Isothiocyanates
[+]

Beta-phenylethyl isothiocyanate and curcumin work synergistically to inhibit prostate cancer cell signaling.Aug 01, 2006

Pubmed Data : Cancer Epidemiol Biomarkers Prev. 2006 Aug;15(8):1526-31. PMID: 16299382
Article Published Date : Aug 01, 2006
Study Type : In Vitro Study
Additional Links
Substances : Curcumin, Phenethyl isothiocyanate
Diseases : Prostate Cancer
Pharmacological Actions : Anticarcinogenic Agents, Antineoplastic Agents, Antiproliferative , Apoptotic, NF-kappaB Inhibitor
Additional Keywords : Isothiocyanates, Natural Substance Synergy
[+]

Combination of xanthohumol and phenethyl isothiocyanate inhibits NF-κB and activates Nrf2 in pancreatic cancer cells.Feb 14, 2020

Pubmed Data : Toxicol In Vitro. 2020 Feb 15:104799. Epub 2020 Feb 15. PMID: 32070777
Article Published Date : Feb 14, 2020
Study Type : In Vitro Study
Additional Links
Substances : Phenethyl isothiocyanate, Xanthohumol
Diseases : Pancreatic Cancer
Pharmacological Actions : Anti-Inflammatory Agents, NF-kappaB Inhibitor, Nrf2 activation
Additional Keywords : Natural Substance Synergy
[+]

Glucosinolate-degradation products as co-adjuvant therapy on prostate cancer in vitro.Oct 08, 2019

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Int J Mol Sci. 2019 Oct 9 ;20(20). Epub 2019 Oct 9. PMID: 31600887
Article Published Date : Oct 08, 2019
Study Type : In Vitro Study
Additional Links
Substances : Indole-3-Carbinol, Isothiocyanates, Phenethyl isothiocyanate, Sulforaphane
Diseases : Prostate Cancer
Pharmacological Actions : Antiproliferative , Apoptotic, Chemosensitizer
Additional Keywords : Chemotherapeutic Synergy: Docetaxel
[+]

In this review, we summarize the cancer chemopreventive role of naturally occurring glucosinolate derivatives as inhibitors of carcinogenesis.Apr 30, 2015

Pubmed Data : Curr Pharmacol Rep. 2015 May ;1(3):179-196. Epub 2015 Jan 30. PMID: 26457242
Article Published Date : Apr 30, 2015
Study Type : In Vitro Study
Additional Links
Substances : Indole-3-Carbinol, Phenethyl isothiocyanate, Sulforaphane
Diseases : Inflammation, Oxidative Stress
Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants, Chemopreventive, MicroRNA modulator, Nrf2 activation
Additional Keywords : DNA Methylation
[+]

Inhibition of autophagy potentiates the anti-metastasis effect of phenethyl isothiocyanate in lung cancer cells.Dec 25, 2017

Pubmed Data : Mol Carcinog. 2017 Dec 26. Epub 2017 Dec 26. PMID: 29278657
Article Published Date : Dec 25, 2017
Study Type : In Vitro Study
Additional Links
Substances : Phenethyl isothiocyanate
Diseases : Lung Cancer
Pharmacological Actions : Anti-metastatic, Autophagy Up-regulation
[+]

Inhibition of glycolysis in prostate cancer chemoprevention by phenethyl isothiocyanate.Mar 14, 2018

Pubmed Data : Cancer Prev Res (Phila). 2018 Mar 15. Epub 2018 Mar 15. PMID: 29545400
Article Published Date : Mar 14, 2018
Study Type : In Vitro Study
Additional Links
Substances : Phenethyl isothiocyanate
Diseases : Prostate Cancer
Pharmacological Actions : Chemopreventive
[+]

Isothiocyanates suppress the invasion and metastasis of tumors.Sep 07, 2017

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Oncotarget. 2017 Sep 8 ;8(38):63949-63962. Epub 2017 Jul 12. PMID: 28969043
Article Published Date : Sep 07, 2017
Study Type : In Vitro Study
Additional Links
Substances : Benzyl isothiocyanate , Phenethyl isothiocyanate
Diseases : Cancers: All
Pharmacological Actions : Anti-metastatic, Matrix metalloproteinase-9 (MMP-9) inhibitor
[+]

Phenethyl isothiocyanate activates leptin signaling and decreases food intake.Dec 31, 2017

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : PLoS One. 2018 ;13(11):e0206748. Epub 2018 Nov 1. PMID: 30383868
Article Published Date : Dec 31, 2017
Study Type : In Vitro Study
Additional Links
Substances : Phenethyl isothiocyanate
Diseases : Obesity
Pharmacological Actions : Appetite Suppresant
Additional Keywords : Anti-Obesity Agents
[+]

Phenethyl isothiocyanate and Benzyl isothiocyanate inhibit human melanoma A375.S2 cell migration and invasion.Jan 10, 2017

Pubmed Data : Anticancer Res. 2017 11 ;37(11):6223-6234. PMID: 29061805
Article Published Date : Jan 10, 2017
Study Type : In Vitro Study
Additional Links
Substances : Benzyl isothiocyanate , Phenethyl isothiocyanate
Diseases : Cancer Metastasis, Melanoma
Pharmacological Actions : Anti-metastatic
Additional Keywords : Isothiocyanates
[+]

Phenethyl isothiocyanate and cisplatin co-encapsulated in a liposomal nanoparticle for treatment of non-small cell lung cancer.Feb 21, 2019

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Molecules. 2019 Feb 22 ;24(4). Epub 2019 Feb 22. PMID: 30813352
Article Published Date : Feb 21, 2019
Study Type : In Vitro Study
Additional Links
Substances : Phenethyl isothiocyanate
Diseases : Carcinoma: Non-Small-Cell Lung
Pharmacological Actions : Chemosensitizer, Chemotherapeutic
Additional Keywords : Chemotherapeutic Synergy: Cisplatin
[+]

Phenethyl isothiocyanate and sulforaphane or curcumin and sulforaphane have a synergistic effect in the inhibition of inflammation.Jan 01, 2009

Pubmed Data : Pharm Res. 2009 Jan;26(1):224-31. Epub 2008 Oct 8. PMID: 18841446
Article Published Date : Jan 01, 2009
Study Type : In Vitro Study
Additional Links
Substances : Curcumin, Phenethyl isothiocyanate, Sulforaphane
Diseases : Inflammation, Lipopolysaccharide-Induced Toxicity
Pharmacological Actions : Anticarcinogenic Agents, Cyclooxygenase 2 Inhibitors, Tumor Necrosis Factor (TNF) Alpha Inhibitor
Additional Keywords : Isothiocyanates, Natural Substance Synergy
[+]

Phenethyl isothiocyanate and ursolic acid protects DNA from oxidative damage.Jan 29, 2018

Pubmed Data : Mol Nutr Food Res. 2018 Jan 30. Epub 2018 Jan 30. PMID: 29383876
Article Published Date : Jan 29, 2018
Study Type : In Vitro Study
Additional Links
Substances : Phenethyl isothiocyanate
Diseases : DNA damage
Pharmacological Actions : Genoprotective
[+]

Phenethyl isothiocyanate has promising anti-osteosarcoma activity.Mar 03, 2020

Pubmed Data : Acta Pharmacol Sin. 2020 Mar 4. Epub 2020 Mar 4. PMID: 32132657
Article Published Date : Mar 03, 2020
Study Type : In Vitro Study
Additional Links
Substances : Phenethyl isothiocyanate
Diseases : Osteosarcoma
Pharmacological Actions : Antiproliferative , Apoptotic, Cell cycle arrest
[+]

Phenethyl isothiocyanate in combination with dibenzoylmethane inhibits the androgen-independent growth of prostate cancer cells.Apr 24, 2018

Pubmed Data : Food Funct. 2018 Apr 25 ;9(4):2398-2408. PMID: 29595853
Article Published Date : Apr 24, 2018
Study Type : In Vitro Study
Additional Links
Substances : Dibenzoylmethane (DBM), Phenethyl isothiocyanate
Diseases : Prostate Cancer
Pharmacological Actions : Antiproliferative , Apoptotic, NF-kappaB Inhibitor, Survivin Down-Regulation
[+]

Phenethyl isothiocyanate induces apoptotic cell death in gefitinib-resistant NCI-H460 human lung cancer cells.Dec 31, 2017

Pubmed Data : Anticancer Res. 2018 04 ;38(4):2137-2147. PMID: 29599332
Article Published Date : Dec 31, 2017
Study Type : In Vitro Study
Additional Links
Substances : Phenethyl isothiocyanate
Diseases : Cancers: Drug Resistant, Lung Cancer
Pharmacological Actions : Apoptotic
Additional Keywords : Isothiocyanates
[+]

Phenethyl isothiocyanate inhibits colorectal cancer stem cells by suppressing Wnt/β-catenin pathway.Nov 30, 2018

Pubmed Data : Phytother Res. 2018 Dec ;32(12):2447-2455. Epub 2018 Aug 30. PMID: 30159926
Article Published Date : Nov 30, 2018
Study Type : In Vitro Study
Additional Links
Substances : Phenethyl isothiocyanate
Diseases : Colorectal Cancer
Pharmacological Actions : Antiproliferative , Wnt/β-catenin signaling pathway modulation
Additional Keywords : Cancer Stem Cells
[+]

Phenethyl isothiocyanate suppresses stemness in the chemo- and radio-resistant triple-negative breast cancer cells.Jan 21, 2020

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Cancers (Basel). 2020 Jan 22 ;12(2). Epub 2020 Jan 22. PMID: 31979093
Article Published Date : Jan 21, 2020
Study Type : In Vitro Study
Additional Links
Substances : Phenethyl isothiocyanate
Diseases : Breast Cancer, Breast Cancer: Triple Negative
Pharmacological Actions : Antiproliferative
Additional Keywords : Cancer Stem Cells
[+]

Phenethyl isothiocyanate suppresses the metastasis of ovarian cancer.Dec 15, 2016

Pubmed Data : Cancer Biol Ther. 2016 Dec 16:1-10. Epub 2016 Dec 16. PMID: 27981892
Article Published Date : Dec 15, 2016
Study Type : In Vitro Study
Additional Links
Substances : Isothiocyanates, Phenethyl isothiocyanate
Diseases : Ovarian Cancer
Pharmacological Actions : Anti-metastatic
[+]

Phenethyl isothiocyanate synergistically induces apoptosis with Gefitinib in non-small cell lung cancer cells.Mar 17, 2020

Pubmed Data : Mol Carcinog. 2020 Mar 18. Epub 2020 Mar 18. PMID: 32189414
Article Published Date : Mar 17, 2020
Study Type : In Vitro Study
Additional Links
Substances : Phenethyl isothiocyanate
Diseases : Carcinoma: Non-Small-Cell Lung
Pharmacological Actions : Antiproliferative
Additional Keywords : Chemotherapeutic Synergy: Gefitinib
[+]

Sequential treatment of phenethyl isothiocyanate increases sensitivity of Temozolomide resistant glioblastoma cells.Dec 31, 2018

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Am J Transl Res. 2019 ;11(2):696-708. Epub 2019 Feb 15. PMID: 30899372
Article Published Date : Dec 31, 2018
Study Type : In Vitro Study
Additional Links
Substances : Phenethyl isothiocyanate
Diseases : Cancers: Drug Resistant, Glioblastoma
Pharmacological Actions : Antiproliferative , Chemosensitizer
Additional Keywords : Chemotherapeutic Synergy: Temozolomide
[+]

Suppression of glutathione S-transferases potentiates the cytotoxic effect of phenethyl isothiocyanate in cholangiocarcinoma cells.Apr 16, 2018

Pubmed Data : Naunyn Schmiedebergs Arch Pharmacol. 2018 Apr 17. Epub 2018 Apr 17. PMID: 29666895
Article Published Date : Apr 16, 2018
Study Type : In Vitro Study
Additional Links
Substances : Phenethyl isothiocyanate
Diseases : Cholangiocarcinoma
Pharmacological Actions : Cytotoxic
[+]

This enhances the understanding of the potential cancer preventive and treatment effects of isothiocyanate compounds prostate cancer.Oct 31, 2018

Pubmed Data : Anticancer Res. 2018 Nov ;38(11):6069-6083. PMID: 30396921
Article Published Date : Oct 31, 2018
Study Type : In Vitro Study
Additional Links
Substances : Phenethyl isothiocyanate
Diseases : Prostate Cancer
Pharmacological Actions : Chemopreventive, Chemotherapeutic

Copyright: lightwise / 123RF Stock Photo

Phenethyl isothiocyanate Related Articles

Can Cabbage Beat Chemo for Cervical Cancer?
Written by GreenMedInfo Research Group
Mainstream medicine’s cancer treatments are far from a cure. In fact, they make cancer more deadly. But new research shows lowly cabbages may be more effective in battling cancer

Print Options

Some features are currently member only features. If you are already a member, please login. Otherwise, click here to become a member.

This website is for information purposes only. By providing the information contained herein we are not diagnosing, treating, curing, mitigating, or preventing any type of disease or medical condition. Before beginning any type of natural, integrative or conventional treatment regimen, it is advisable to seek the advice of a licensed healthcare professional.

© Copyright 2008-2020 GreenMedInfo.com, Journal Articles copyright of original owners, MeSH copyright NLM.