Prickly Pear Cactus

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23 Diseases Researched for Prickly Pear Cactus
NameACCKFocus
Clotting110Locked
Gastroesophageal Reflux110Locked
High Fat Diet24Locked
Obesity24Locked
Cervical Cancer12Locked
Diabetes: Oxidative Stress12Locked
High Sugar Diet12Locked
Hypoglycemia12Locked
Nickel Poisoning12Locked
Oxidative Stress22Locked
Alcohol Toxicity 11Locked
Carcinoma: Non-Small-Cell Lung11Locked
Colorectal Cancer11Locked
DNA damage11Locked
Enveloped Viruses11Locked
Glioma11Locked
HSV-211Locked
Immune Disorders: Low Immune Function11Locked
Inflammation11Locked
Influenza A11Locked
Lipopolysaccharide-Induced Toxicity11Locked
Liver Damage11Locked
Polio11Locked
22 Pharmacological Actions Researched for Prickly Pear Cactus
NameACCKFocus
Anti-Platelet110Locked
Antioxidants46Locked
Cell cycle arrest45Locked
Hypoglycemic Agents24Locked
Antiproliferative 33Locked
Hepatoprotective23Locked
Tumor Suppressor Protein p53 Upregulation23Locked
Anti-Inflammatory Agents12Locked
Apoptotic22Locked
Gastrointestinal Agents12Locked
Malondialdehyde Down-regulation12Locked
Neuromodulatory12Locked
Neuroprotective Agents12Locked
P21 Activation12Locked
Superoxide Dismutase Up-regulation12Locked
Antineoplastic Agents11Locked
Antiviral Agents11Locked
Chemopreventive11Locked
Cyclin-dependent kinase inhibitor: P16INK411Locked
Genoprotective11Locked
Immunomodulatory11Locked
Interleukin-6 Downregulation11Locked

View the Evidence:
64 Abstracts with Prickly Pear Cactus Research

[+]

Mucosave formulation is an effective treatment for reducing the frequency and intensity of symptoms associated with gastroesophageal reflux.Dec 31, 2015

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Evid Based Complement Alternat Med. 2016 ;2016:2581461. Epub 2016 Aug 12. PMID: 27818697
Article Published Date : Dec 31, 2015
Study Type : Human Study
Additional Links
Substances : Olive, Prickly Pear Cactus, Sodium Bicarbonate
Diseases : Gastroesophageal Reflux
Additional Keywords : Plant Extracts
[+]

Nopal fiber (Opuntia ficus-indica) improves symptoms in irritable bowel syndrome in the short term.Sep 15, 2020

Pubmed Data : Neurogastroenterol Motil. 2020 Sep 16:e13986. Epub 2020 Sep 16. PMID: 32935904
Article Published Date : Sep 15, 2020
Study Type : Human Study
Additional Links
Substances : Fiber, Prickly Pear Cactus
Diseases : Irritable Bowel Syndrome
Pharmacological Actions : Gastrointestinal Agents
[+]

Opuntia ficus-indica stem administration in participant’s 70 years of age shows a positive effect on overall cognitive function.Oct 31, 2020

Pubmed Data : J Med Food. 2020 Nov ;23(11):1146-1154. Epub 2020 Oct 2. PMID: 33006504
Article Published Date : Oct 31, 2020
Study Type : Human Study
Additional Links
Substances : Prickly Pear Cactus
Diseases : Aging: Brain , Cognitive Decline/Dysfunction
Pharmacological Actions : Neuroprotective Agents
[+]

Opuntia may benefit heart health by decreasing platelet activity.Jul 01, 2003

Pubmed Data : Prostaglandins Leukot Essent Fatty Acids. 2003 Jul;69(1):61-6. PMID: 12878452
Article Published Date : Jul 01, 2003
Study Type : Human Study
Additional Links
Substances : Prickly Pear Cactus
Diseases : Clotting
Pharmacological Actions : Anti-Platelet
[+]

An ethanolic extract of Opuntia ficus-indica ameliorates cognitive dysfunction induced by cholinergic blockade.Sep 30, 2018

Pubmed Data : J Med Food. 2018 Oct ;21(10):971-978. Epub 2018 Jul 25. PMID: 30044674
Article Published Date : Sep 30, 2018
Study Type : Animal Study
Additional Links
Substances : Prickly Pear Cactus
Diseases : Cognitive Decline/Dysfunction
Pharmacological Actions : Brain-derived neurotrophic factor modulator, Neuroprotective Agents
[+]

Anti-nociceptive and anti-inflammatory effects of the methanolic extract of Opuntia humifusa stem.Jun 30, 2017

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Avicenna J Phytomed. 2017 Jul-Aug;7(4):366-375. PMID: 28884086
Article Published Date : Jun 30, 2017
Study Type : Animal Study
Additional Links
Substances : Prickly Pear Cactus
Diseases : Inflammation, Rheumatoid Arthritis
Pharmacological Actions : Anti-Inflammatory Agents, Antinoceceptive
[+]

Cactus cladodes extract minimizes the effects of UV irradiation on keratinocytes and hairless mice.Nov 30, 2017

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Pharm Biol. 2017 Dec ;55(1):1032-1040. PMID: 28183235
Article Published Date : Nov 30, 2017
Study Type : Animal Study
Additional Links
Substances : Prickly Pear Cactus
Diseases : Ultraviolet Radiation Induced Damage
Pharmacological Actions : Photoprotective
Additional Keywords : Plant Extracts
[+]

Cactus cladodes extract was effective in protecting the small intestine against methotrexate-induced damage.Aug 31, 2018

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : J Cancer Res Ther. 2018 Sep ;14(Supplement):S779-S784. PMID: 30249903
Article Published Date : Aug 31, 2018
Study Type : Animal Study
Additional Links
Substances : Prickly Pear Cactus
Diseases : Drug Toxicity: Methotrexate, Lipid Peroxidation, Oxidative Stress
Pharmacological Actions : Antioxidants, Gastroprotective
Additional Keywords : Plant Extracts
[+]

Cactus pear seed oil has antihyperglycemic effects explained partly by inhibition of intestinal glucose absorption.Sep 30, 2014

Pubmed Data : Pharm Biol. 2014 Oct ;52(10):1286-90. Epub 2014 Jul 15. PMID: 25026333
Article Published Date : Sep 30, 2014
Study Type : Animal Study
Additional Links
Substances : Prickly Pear Cactus
Diseases : Hypoglycemia
Pharmacological Actions : Hypoglycemic Agents
Additional Keywords : Plant Extracts, Plant Oils
[+]

Carob leaves and prickly pear cactus cladodes might alleviate inflammation severity associated with obesity and colitis.Nov 30, 2017

Pubmed Data : Biomed Pharmacother. 2017 Dec ;96:1022-1035. Epub 2017 Dec 6. PMID: 29221725
Article Published Date : Nov 30, 2017
Study Type : Animal Study
Additional Links
Substances : Carob, Prickly Pear Cactus
Diseases : Colitis, Inflammation, Obesity
Pharmacological Actions : Anti-Inflammatory Agents
[+]

Eastern prickly pear extract may be a promising candidate for treating human cervical carcinoma.Dec 31, 2014

Pubmed Data : J Med Food. 2015 Jan ;18(1):31-44. PMID: 25379883
Article Published Date : Dec 31, 2014
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Prickly Pear Cactus
Diseases : Cervical Cancer
Pharmacological Actions : Antioxidants, Cell cycle arrest, P21 Activation, Tumor Suppressor Protein p53 Upregulation
Additional Keywords : Phytotherapy, Plant Extracts
[+]

Fresh fruit juice of Opuntia dillenii Haw. attenuates acetic acid-induced ulcerative colitis in rats.Jun 28, 2018

Pubmed Data : J Diet Suppl. 2018 Jun 29:1-12. Epub 2018 Jun 29. PMID: 29958056
Article Published Date : Jun 28, 2018
Study Type : Animal Study
Additional Links
Substances : Prickly Pear Cactus
Diseases : Ulcerative Colitis
Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants
[+]

Gel and aqueous extract of Opuntia ficus-indica cladode have a significant diuretic effect.Aug 31, 2017

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Asian Pac J Trop Med. 2017 Sep ;10(9):900-906. Epub 2017 Sep 13. PMID: 29080620
Article Published Date : Aug 31, 2017
Study Type : Animal Study
Additional Links
Substances : Prickly Pear Cactus
Pharmacological Actions : Antidiuretic Agents
[+]

Hepatoprotective effect of Opuntia microdasys (Lehm.) Pfeiff flowers against diabetes type II induced in rats.Sep 30, 2017

Pubmed Data : Biomed Pharmacother. 2017 Oct ;94:79-87. Epub 2017 Jul 26. PMID: 28755576
Article Published Date : Sep 30, 2017
Study Type : Animal Study
Additional Links
Substances : Prickly Pear Cactus
Diseases : Diabetes Mellitus: Type 2
Pharmacological Actions : Alpha-glucosidase inhibitor , Antioxidants
Additional Keywords : Drug: Metformin, Plant Extracts
[+]

Hypoglycemic effect of Opuntia ficus-indica var. saboten is due to enhanced peripheral glucose uptake.Dec 08, 2016

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Nutrients. 2016 Dec 9 ;8(12). Epub 2016 Dec 9. PMID: 27941667
Article Published Date : Dec 08, 2016
Study Type : Animal Study
Additional Links
Substances : Prickly Pear Cactus
Diseases : Hyperglycemia, Hyperinsulinism, Insulin Resistance
Pharmacological Actions : Alpha-glucosidase inhibitor , Hypoglycemic Agents
Additional Keywords : Plant Extracts
[+]

Indicaxanthin from prickly pear cactus impairs melanoma cell proliferation, invasiveness, and tumor progression.Nov 14, 2018

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Phytomedicine. 2018 Nov 15 ;50:19-24. Epub 2018 Sep 18. PMID: 30466978
Article Published Date : Nov 14, 2018
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Prickly Pear Cactus
Diseases : Melanoma
Pharmacological Actions : Anti-metastatic, Antiproliferative , Apoptotic
[+]

Indicaxanthin was found to cross the blood brain barrier and modulate glutamate-induced neuronal excitation.Jul 30, 2015

Pubmed Data : J Agric Food Chem. 2015 Jul 31. Epub 2015 Jul 31. PMID: 26227670
Article Published Date : Jul 30, 2015
Study Type : Animal Study
Additional Links
Substances : Prickly Pear Cactus
Pharmacological Actions : Neuromodulatory
Additional Keywords : Blood Brain Barrier, Dose Response
[+]

Nopal water extract could be considered for the prevention and treatment of blood glucose and a potential use as a dietary supplement.Dec 31, 2016

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Evid Based Complement Alternat Med. 2017 ;2017:4380721. Epub 2017 Feb 20. PMID: 28303158
Article Published Date : Dec 31, 2016
Study Type : Animal Study
Additional Links
Substances : Prickly Pear Cactus
Diseases : Diabetes Mellitus: Type 2, High Fat Diet
Pharmacological Actions : Hypoglycemic Agents
[+]

O. humifusa is a potential anti-asthmatic functional food.Dec 31, 2016

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Food Nutr Res. 2017 ;61(1):1393307. Epub 2017 Oct 24. PMID: 29151835
Article Published Date : Dec 31, 2016
Study Type : Animal Study
Additional Links
Substances : Prickly Pear Cactus
Diseases : Asthma, Immune Dysregulation: TH1/TH2 imbalance
Pharmacological Actions : Anti-Asthmatic Agents, Immunomodulatory
[+]

O. humifusa supplementation might play an important role for improving insulin sensitivity in rat skeletal muscle.Mar 27, 2013

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Int J Mol Sci. 2013 Mar 28 ;14(4):7140-54. Epub 2013 Mar 28. PMID: 23538842
Article Published Date : Mar 27, 2013
Study Type : Animal Study
Additional Links
Substances : Prickly Pear Cactus
Diseases : Insulin Resistance
Pharmacological Actions : Insulin Sensitizers
Additional Keywords : Plant Extracts
[+]

Opuntia cladode powders inhibit adipogenesis in 3 T3-F442A adipocytes and a high-fat-diet rat model.Feb 04, 2020

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : BMC Complement Med Ther. 2020 Feb 5 ;20(1):33. Epub 2020 Feb 5. PMID: 32024512
Article Published Date : Feb 04, 2020
Study Type : Animal Study
Additional Links
Substances : Prickly Pear Cactus
Diseases : High Fat Diet, Obesity
Additional Keywords : Anti-Obesity Agents
[+]

Opuntia dillenii Haw fruits have hypoglycemic and antioxidant properties that protected rats from STZ-induced oxidative damage.Jun 24, 2015

Pubmed Data : Carbohydr Polym. 2015 Jun 25 ;124:25-34. Epub 2015 Feb 12. PMID: 25839790
Article Published Date : Jun 24, 2015
Study Type : Animal Study
Additional Links
Substances : Prickly Pear Cactus
Diseases : Diabetes: Oxidative Stress
Pharmacological Actions : Antioxidants, Hypoglycemic Agents, Malondialdehyde Down-regulation, Superoxide Dismutase Up-regulation
[+]

Opuntia extracts are hepatoprotective and can be used as a nutraceutical to prevent acute liver failure.Oct 03, 2016

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Nutrients. 2016 Oct 4 ;8(10). Epub 2016 Oct 4. PMID: 27782042
Article Published Date : Oct 03, 2016
Study Type : Animal Study
Additional Links
Substances : Prickly Pear Cactus
Diseases : Acetaminophen (Tylenol) Toxicity
Pharmacological Actions : Antioxidants, Hepatoprotective
Additional Keywords : Phytotherapy, Plant Extracts
Problem Substances : Acetaminophen, Paracetamol
[+]

Opuntia ficus indica fruits ameliorate cisplatin-induced nephrotoxicity. Dec 31, 2019

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Biol Pharm Bull. 2020 ;43(5):831-838. PMID: 32378560
Article Published Date : Dec 31, 2019
Study Type : Animal Study
Additional Links
Substances : Prickly Pear Cactus
Diseases : Chemotherapy-Induced Toxicity: Cisplatin
Pharmacological Actions : Chemoprotective Agents, Renoprotective
[+]

Opuntia ficus indica seed oil exhibited potent antioxidant, prophylactic, and therapeutic potentials against acute gastric ulcer.Dec 31, 2018

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Oxid Med Cell Longev. 2019 ;2019:1568720. Epub 2019 Nov 15. PMID: 31827668
Article Published Date : Dec 31, 2018
Study Type : Animal Study
Additional Links
Substances : Prickly Pear Cactus
Diseases : Gastric Ulcer
Pharmacological Actions : Gastroprotective
[+]

Opuntia ficus-indica might be promising candidate for treating Alzheimer disease.Sep 30, 2020

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Saudi J Biol Sci. 2020 Oct ;27(10):2829-2838. Epub 2020 Jul 9. PMID: 32994743
Article Published Date : Sep 30, 2020
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Prickly Pear Cactus
Diseases : Aluminum Toxicity , Alzheimer's Disease
Pharmacological Actions : Acetylcholinesterase Inhibitor, Anti-Inflammatory Agents, Antioxidants, Neuroprotective Agents, Tumor Necrosis Factor (TNF) Alpha Inhibitor
Problem Substances : Aluminum Chloride
[+]

Opuntia humifusa ameliorated cerulein-induced acute pancreatitis.Dec 31, 2013

Pubmed Data : Pancreas. 2014 Jan ;43(1):118-27. PMID: 24326366
Article Published Date : Dec 31, 2013
Study Type : Animal Study
Additional Links
Substances : Prickly Pear Cactus
Diseases : Pancreatitis
Pharmacological Actions : Anti-Apoptotic, Anti-Inflammatory Agents, Pancreato Protective Agents
Additional Keywords : Plant Extracts
[+]

Opuntia humifusa stems lower blood glucose and cholesterol levels in streptozotocin-induced diabetic rats.May 31, 2011

Pubmed Data : Nutr Res. 2011 Jun ;31(6):479-87. Epub 2011 Jun 12. PMID: 21745630
Article Published Date : May 31, 2011
Study Type : Animal Study
Additional Links
Substances : Prickly Pear Cactus
Diseases : High Cholesterol, Hypoglycemia
Pharmacological Actions : Hypoglycemic Agents, Hypolipidemic
Additional Keywords : Phytotherapy, Plant Extracts
[+]

Opuntia humifusa water extract ameliorates loperamide-induced constipation in rats.Jan 16, 2017

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : BMC Complement Altern Med. 2017 Jan 17 ;17(1):49. Epub 2017 Jan 17. PMID: 28095842
Article Published Date : Jan 16, 2017
Study Type : Animal Study
Additional Links
Substances : Prickly Pear Cactus
Diseases : Constipation
Pharmacological Actions : Laxative
Additional Keywords : Plant Extracts
[+]

Opuntia protects against nickel-induced toxicity in rats.Dec 01, 2008

Pubmed Data : Food Chem Toxicol. 2008 Dec;46(12):3759-63. Epub 2008 Oct 4. PMID:18950672
Article Published Date : Dec 01, 2008
Study Type : Animal Study
Additional Links
Substances : Prickly Pear Cactus
Diseases : Nickel Poisoning
[+]

Polysaccharides from Opuntia milpa alta alleviate alloxan-induced INS-1 cells apoptosis.Dec 31, 2019

Pubmed Data : Nutr Res. 2020 05 ;77:108-118. Epub 2020 Feb 6. PMID: 32422500
Article Published Date : Dec 31, 2019
Study Type : Animal Study
Additional Links
Substances : Prickly Pear Cactus
Diseases : Alloxan toxicity
Pharmacological Actions : Anti-Apoptotic, Antioxidants, Nrf2 activation
Additional Keywords : Polysaccharides
Problem Substances : Alloxan
[+]

Polysaccharides from Opuntia stricta significantly prevented hypercholesterolaemia-induced elevation of serum biomarkers.Sep 30, 2017

Pubmed Data : Arch Physiol Biochem. 2017 Oct ;123(4):225-237. Epub 2017 Apr 3. PMID: 28372462
Article Published Date : Sep 30, 2017
Study Type : Animal Study
Additional Links
Substances : Prickly Pear Cactus
Diseases : Hyperlipidemia, Lipid Peroxidation, Oxidative Stress
Pharmacological Actions : Anti-Apoptotic, Antioxidants, Hypolipidemic
Additional Keywords : Plant Extracts, Polysaccharides
[+]

Pomegranate, apple and prickly pear vinegars may prevent HFD-induced obesity and obesity-related cardiac complications.Sep 04, 2016

Pubmed Data : Pharm Biol. 2016 Sep 5:1-10. Epub 2016 Sep 5. PMID: 27595296
Article Published Date : Sep 04, 2016
Study Type : Animal Study
Additional Links
Substances : Apple Cider Vinegar, Pomegranate, Prickly Pear Cactus, Vinegar
Diseases : High Fat Diet, Obesity
Pharmacological Actions : Anti-Inflammatory Agents
Additional Keywords : Anti-Obesity Agents
[+]

Prickly pear juice at two distinct phases of maturity has different phytochemical characteristics and opposite effects on gastrointestinal actions.May 31, 2018

Pubmed Data : J Med Food. 2018 Jun ;21(6):617-624. Epub 2018 Feb 28. PMID: 29489444
Article Published Date : May 31, 2018
Study Type : Animal Study
Additional Links
Substances : Prickly Pear Cactus
Diseases : Constipation
Pharmacological Actions : Gastrointestinal Agents
Additional Keywords : Plant Extracts
[+]

The nephroprotective potential of prickly pear cactus against sodium dichromate toxicity might be due to its antioxidant properties.Aug 06, 2018

Pubmed Data : Appl Physiol Nutr Metab. 2018 Aug 7. Epub 2018 Aug 7. PMID: 30086244
Article Published Date : Aug 06, 2018
Study Type : Animal Study
Additional Links
Substances : Prickly Pear Cactus
Diseases : Kidney Damage: Chemically-Induced
Pharmacological Actions : Renoprotective
[+]

The results conclude that betanin can effectively suppress renal fibrosis in diabetic nephropathy.Feb 22, 2017

Pubmed Data : J Ethnopharmacol. 2017 Feb 23 ;198:432-443. Epub 2017 Jan 20. PMID: 28111218
Article Published Date : Feb 22, 2017
Study Type : Animal Study
Additional Links
Substances : Betanin, Prickly Pear Cactus
Diseases : Diabetic Nephropathy
Pharmacological Actions : Anti-Fibrotic, Renoprotective
[+]

These results suggest that O. humifusa exerts chemopreventive effects on chemical carcinogenesis.Dec 31, 2011

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Asian Pac J Cancer Prev. 2012 ;13(9):4655-60. PMID: 23167397
Article Published Date : Dec 31, 2011
Study Type : Animal Study
Additional Links
Substances : Prickly Pear Cactus
Diseases : Lipid Peroxidation, Oxidative Stress, Skin Cancer
Pharmacological Actions : Anticarcinogenic Agents, Chemopreventive, Phase II Detoxification Enzyme Inducer, Superoxide Dismutase Up-regulation
Additional Keywords : Phytotherapy
[+]

These results suggest that O. humifusa supplementation has a positive effect on bone density.Dec 31, 2011

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Int J Mol Sci. 2012 ;13(6):6747-56. Epub 2012 Jun 4. PMID: 22837661
Article Published Date : Dec 31, 2011
Study Type : Animal Study
Additional Links
Substances : Prickly Pear Cactus
Diseases : Osteoporosis
Pharmacological Actions : Osteoprotective
[+]

This study confirmed the claimed use of the plant against anxiety in Turkish folk medicine.Apr 15, 2020

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Molecules. 2020 Apr 16 ;25(8). Epub 2020 Apr 16. PMID: 32316321
Article Published Date : Apr 15, 2020
Study Type : Animal Study
Additional Links
Substances : Prickly Pear Cactus
Diseases : Anxiety
Pharmacological Actions : Anti-Anxiety Agents, Hypnotics and Sedatives
[+]

This study supports the use of nopal as a functional food and prebiotic for its ability to modify gut microbiota.Jul 04, 2017

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Sci Rep. 2017 Jul 5 ;7(1):4716. Epub 2017 Jul 5. PMID: 28680065
Article Published Date : Jul 04, 2017
Study Type : Animal Study
Additional Links
Substances : Prickly Pear Cactus
Diseases : High Fat Diet, High Sugar Diet, Obesity
Pharmacological Actions : Gastrointestinal Agents, Hepatoprotective, Neuroprotective Agents
Additional Keywords : Microbiota
[+]

Anti-proliferative and apoptosis-inducing activity of Acacia modesta and Opuntia monocantha extracts on HeLa cells.Sep 30, 2020

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Asian Pac J Cancer Prev. 2020 Oct 1 ;21(10):3125-3131. Epub 2020 Oct 1. PMID: 33112576
Article Published Date : Sep 30, 2020
Study Type : In Vitro Study
Additional Links
Substances : Prickly Pear Cactus
Diseases : Cervical Cancer
Pharmacological Actions : Antioxidants, Antiproliferative , Apoptotic, Tumor Suppressor Protein p53 Upregulation
[+]

Biochemical and biophysical characterization of water-soluble pectin from Opuntia ficus-indica and its potential cytotoxic activity.Sep 30, 2018

Pubmed Data : Phytochemistry. 2018 Oct ;154:47-55. Epub 2018 Jun 30. PMID: 30006087
Article Published Date : Sep 30, 2018
Study Type : In Vitro Study
Additional Links
Substances : Prickly Pear Cactus
Diseases : Neuroblastoma
Pharmacological Actions : Antiproliferative
Additional Keywords : Selective Cytotoxicity
[+]

Cactus pear juice fermented with L. plantarum S-811 as a functional beverage for the prevention of obesity and related pathologies.Feb 19, 2019

Pubmed Data : Food Funct. 2019 Feb 20 ;10(2):1085-1097. PMID: 30720817
Article Published Date : Feb 19, 2019
Study Type : In Vitro Study
Additional Links
Substances : Fermented Foods and Beverages, Lactobacillus plantarum, Prickly Pear Cactus
Diseases : Obesity
Pharmacological Actions : Hypoglycemic Agents, Hypolipidemic
Additional Keywords : Anti-Obesity Agents
[+]

Cactus polysaccharides have anti-tumor activity on lung squamous carcinoma cells.Dec 31, 2013

Pubmed Data : Afr J Tradit Complement Altern Med. 2014 ;11(5):99-104. Epub 2014 Aug 23. PMID: 25395712
Article Published Date : Dec 31, 2013
Study Type : In Vitro Study
Additional Links
Substances : Prickly Pear Cactus
Diseases : Carcinoma: Non-Small-Cell Lung
Pharmacological Actions : Antiproliferative , Apoptotic, Cell cycle arrest, Tumor Suppressor Protein p53 Upregulation
Additional Keywords : Plant Extracts
[+]

Chemopreventive effect of cactus extracts in human colon and breast cancer cells.Apr 29, 2013

Pubmed Data : Food Funct. 2013 Apr 30 ;4(5):681-8. PMID: 23435602
Article Published Date : Apr 29, 2013
Study Type : In Vitro Study
Additional Links
Substances : Flavonoids, Prickly Pear Cactus
Diseases : Breast Cancer, Colon Cancer
Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants, Apoptotic, Chemopreventive, Cyclooxygenase 2 Inhibitors
Additional Keywords : Plant Extracts
[+]

Compounds from prickly pear have virucidal activity against enveloped viruses.Sep 11, 2010

Pubmed Data : J Nat Med. 2010 Sep 11. Epub 2010 Sep 11. PMID: 20835849
Article Published Date : Sep 11, 2010
Study Type : In Vitro Study
Additional Links
Substances : Prickly Pear Cactus
Diseases : Enveloped Viruses, HSV-2, Influenza A, Polio
Pharmacological Actions : Antiviral Agents
[+]

Extracts of Opuntia humifusa fruits inhibit the growth of AGS human gastric adenocarcinoma cells.Feb 29, 2016

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Prev Nutr Food Sci. 2016 Mar ;21(1):31-7. Epub 2016 Mar 31. PMID: 27069903
Article Published Date : Feb 29, 2016
Study Type : In Vitro Study
Additional Links
Substances : Prickly Pear Cactus
Diseases : Gastric Cancer
Pharmacological Actions : Antiproliferative , Apoptotic, Cell cycle arrest
Additional Keywords : Dose Response
[+]

Flavonoids from Opuntia ficus-indica were found to have hepatoprotective properties against liver damage by alcoholic oxidative stress.Jun 30, 2017

Pubmed Data : Pharmacogn Mag. 2017 Jul-Sep;13(51):472-476. Epub 2017 Jul 19. PMID: 28839374
Article Published Date : Jun 30, 2017
Study Type : In Vitro Study
Additional Links
Substances : Prickly Pear Cactus
Diseases : Alcohol Toxicity , Liver Damage, Oxidative Stress
Pharmacological Actions : Antioxidants, Hepatoprotective
Additional Keywords : Plant Extracts
[+]

Immunostimulatory activity of Opuntia ficus cladodes fermented by Lactobacillus plantarum and Bacillus subtilis.Jan 31, 2017

Pubmed Data : J Med Food. 2017 Feb ;20(2):131-139. PMID: 28146407
Article Published Date : Jan 31, 2017
Study Type : In Vitro Study
Additional Links
Substances : Prickly Pear Cactus
Diseases : Lipopolysaccharide-Induced Toxicity
Pharmacological Actions : Immunostimulatory
[+]

Indicaxanthin from cactus pear fruit may have chemopreventive potential in colorectal carcinoma at nutritionally relevant amounts.Jul 17, 2014

Pubmed Data : Biochem Biophys Res Commun. 2014 Jul 18 ;450(1):652-8. Epub 2014 Jun 14. PMID: 24937448
Article Published Date : Jul 17, 2014
Study Type : In Vitro Study
Additional Links
Substances : Prickly Pear Cactus
Diseases : Colorectal Cancer
Pharmacological Actions : Antineoplastic Agents, Antiproliferative , Apoptotic, Cell cycle arrest, Chemopreventive, Cyclin-dependent kinase inhibitor: P16INK4
Additional Keywords : Gene Expression Regulation, Plant Extracts, Reactivation Of Tumor Suppressor Gene
[+]

Indicaxanthin from Opuntia ficus indica Inhibits oxidized LDL-mediated human endothelial cell dysfunction.Dec 31, 2018

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Oxid Med Cell Longev. 2019 ;2019:3457846. Epub 2019 Feb 18. PMID: 30911345
Article Published Date : Dec 31, 2018
Study Type : In Vitro Study
Additional Links
Substances : Prickly Pear Cactus
Diseases : Atherosclerosis, Cholesterol: Oxidation, Endothelial Damage
Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants, NF-kappaB Inhibitor
[+]

Isolation and characterization of opuntiol from Opuntia Ficus indica and its antiproliferative effect in KB oral carcinoma cells.Nov 11, 2019

Pubmed Data : Nat Prod Res. 2019 Nov 12:1-5. Epub 2019 Nov 12. PMID: 31711321
Article Published Date : Nov 11, 2019
Study Type : In Vitro Study
Additional Links
Substances : Prickly Pear Cactus
Diseases : Oral Cancer
Pharmacological Actions : Antiproliferative
[+]

Isorhamnetin glycoside isolated from Opuntia ficus-indica induces apoptosis in human colon cancer cells.Aug 31, 2019

Pubmed Data : Chem Biol Interact. 2019 Sep 1 ;310:108734. Epub 2019 Jul 2. PMID: 31276661
Article Published Date : Aug 31, 2019
Study Type : In Vitro Study
Additional Links
Substances : Prickly Pear Cactus
Diseases : Colon Cancer
Pharmacological Actions : Apoptotic
Additional Keywords : Plant Extracts
[+]

Lignans from Opuntia ficus-indica seeds protect rat primary hepatocytes and HepG2 cells against ethanol-induced oxidative stress.Dec 31, 2016

Pubmed Data : Biosci Biotechnol Biochem. 2017 Jan ;81(1):181-183. Epub 2016 Sep 22. PMID: 27885940
Article Published Date : Dec 31, 2016
Study Type : In Vitro Study
Additional Links
Substances : Lignans, Prickly Pear Cactus
Diseases : Alcohol Toxicity , Oxidative Stress
Pharmacological Actions : Antioxidants, Heme oxygenase-1 up-regulation, Hepatoprotective
[+]

O. humifusa fruit water extract has a preventive effect against solar ultraviolet-induced skin damage via suppression of pathways triggered by ROS.Aug 23, 2018

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Int J Mol Sci. 2018 Aug 24 ;19(9). Epub 2018 Aug 24. PMID: 30149526
Article Published Date : Aug 23, 2018
Study Type : In Vitro Study
Additional Links
Substances : Prickly Pear Cactus
Diseases : Ultraviolet Radiation Induced Damage
Pharmacological Actions : Antioxidants, Matrix metalloproteinase-1 (MMP-1) inhibitor
[+]

Opuntia contains immunomodulatory compounds with therapeutic properties.Oct 01, 2008

Pubmed Data : Int Immunopharmacol. 2008 Oct;8(10):1455-66. Epub 2008 Jul 1. PMID: 18597716
Article Published Date : Oct 01, 2008
Study Type : In Vitro Study
Additional Links
Substances : Prickly Pear Cactus
Diseases : Immune Disorders: Low Immune Function
Pharmacological Actions : Immunomodulatory
[+]

Opuntia ficus-indica preparations are a rich source of minerals mainly potassium and calcium.Aug 04, 2015

Pubmed Data : Plant Foods Hum Nutr. 2015 Aug 5. Epub 2015 Aug 5. PMID: 26243666
Article Published Date : Aug 04, 2015
Study Type : In Vitro Study
Additional Links
Substances : Flavonoids, Polyphenols, Prickly Pear Cactus
Additional Keywords : Plant Extracts
[+]

Opuntia protects may protect against the genotoxicity of multiple food contaminants.Dec 27, 2008

Pubmed Data : Food Chem Toxicol. 2008 Dec 27. PMID: 19152824
Article Published Date : Dec 27, 2008
Study Type : In Vitro Study
Additional Links
Substances : Prickly Pear Cactus
Diseases : DNA damage
Pharmacological Actions : Genoprotective
[+]

Prickly pear (Opuntia humifusa) exhibits anti-inflammatory and antioxidant activity.Jan 01, 2006

Pubmed Data : J Pharm Pharmacol. 2006 Jan;58(1):113-9. PMID: 16393471
Article Published Date : Jan 01, 2006
Study Type : In Vitro Study
Additional Links
Substances : Prickly Pear Cactus
Diseases : Inflammation, Lipopolysaccharide-Induced Toxicity, Oxidative Stress
Pharmacological Actions : Antioxidants, Interleukin-6 Downregulation
Additional Keywords : Plant Extracts
[+]

Prickly pear (Opuntia humifusa) inhibits the growth of human glioblastoma cells.Sep 01, 2010

Pubmed Data : Plant Foods Hum Nutr. 2010 Sep;65(3):247-52. PMID: 20814744
Article Published Date : Sep 01, 2010
Study Type : In Vitro Study
Additional Links
Substances : Prickly Pear Cactus
Diseases : Glioma
Pharmacological Actions : Antiproliferative , Cell cycle arrest
[+]

Protective effect of cactus cladode extracts on peroxisomal functions in microglial BV-2 cells activated by different lipopolysaccharides.Jan 06, 2017

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Molecules. 2017 Jan 7 ;22(1). Epub 2017 Jan 7. PMID: 28067864
Article Published Date : Jan 06, 2017
Study Type : In Vitro Study
Additional Links
Substances : Prickly Pear Cactus
Diseases : Lipopolysaccharide-Induced Toxicity
Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants, Neuroprotective Agents
Additional Keywords : Plant Extracts
[+]

Reverse screening on indicaxanthin from Opuntia ficus-indica as natural chemoactive and chemopreventive agent.Oct 13, 2018

Pubmed Data : J Theor Biol. 2018 Oct 14 ;455:147-160. Epub 2018 Jul 17. PMID: 30030079
Article Published Date : Oct 13, 2018
Study Type : In Vitro Study
Additional Links
Substances : Prickly Pear Cactus
Diseases : Breast Cancer, Prostate Cancer, Thyroid Cancer
Pharmacological Actions : Chemopreventive
[+]

The current study highlight the anti-inflammatory property of pumpkin, linseed, and prickly pear oils on carrageenan-induced acute inflammation.Dec 31, 2019

Pubmed Data : Biomed Res Int. 2020 ;2020:5643465. Epub 2020 Aug 2. PMID: 32802857
Article Published Date : Dec 31, 2019
Study Type : In Vitro Study
Additional Links
Substances : Prickly Pear Cactus, Pumpkin Seeds
Diseases : Inflammation, Oxidative Stress
Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants
[+]

The phytochemical indicaxanthin synergistically enhances cisplatin-induced apoptosis in HeLa cells.Jul 01, 2020

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Biomolecules. 2020 Jul 2 ;10(7). Epub 2020 Jul 2. PMID: 32630700
Article Published Date : Jul 01, 2020
Study Type : In Vitro Study
Additional Links
Substances : Prickly Pear Cactus
Diseases : Cervical Cancer
Pharmacological Actions : Chemosensitizer, P21 Activation, Tumor Suppressor Protein p53 Upregulation
Additional Keywords : Chemotherapeutic Synergy: Cisplatin

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