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63 Diseases Researched for Sage
NameACCKFocus
Alzheimer's Disease431Locked
Hot Flash220Locked
Lung Cancer211Locked
Candidiasis: Vulvovaginal110Locked
Cognitive Decline/Dysfunction110Locked
Dementia110Locked
Dental Plaque110Locked
Erythema110Locked
Hyperthyroidism110Locked
Menopausal Syndrome110Locked
Mood Disorders110Locked
Oxidative Stress610Locked
Pharyngeal Diseases110Locked
Pharyngitis110Locked
Premenstrual syndrome110Locked
Smoking110Locked
Sore Throat110Locked
Thyroid Cancer110Locked
Colon Cancer34Locked
High Fat Diet24Locked
Neuropathic Pain23Locked
Anxiety12Locked
Candida Infection 22Locked
Cervical Cancer22Locked
Depression12Locked
Diabetes Mellitus: Type 212Locked
Diabetes: Memory Problems12Locked
Glioblastoma22Locked
Hyperlipidemia12Locked
Insulin Resistance12Locked
Lipopolysaccharide-Induced Toxicity12Locked
Liver Cancer22Locked
Liver Damage: Drug-Induced12Locked
Liver Disease: Oxidative Stress12Locked
Melanoma22Locked
Morphine Tolerance/Dependence12Locked
Obesity12Locked
Polycystic Ovary Syndrome12Locked
Preneoplastic Conditions12Locked
Pseudomonas aeruginosa22Locked
Pulmonary Fibrosis: Bleomycin-Induced12Locked
Sciatic Nerve Crush Injury12Locked
Testicular Injury: Chemical/Metal Induced12Locked
Acute Myeloid Leukemia11Locked
Alcohol Toxicity 11Locked
Breast Cancer11Locked
Cholera11Locked
Foodborne Pathogens: Prevention/Food Preservation11Locked
Gastric Ulcer11Locked
HIV Infections11Locked
HSV-111Locked
HSV-211Locked
Herpes family viruses11Locked
Inflammation11Locked
Kidney Cancer11Locked
Leukemia11Locked
MRSA11Locked
Malignant Melanoma11Locked
Neurodegenerative Diseases11Locked
Staphylococcus aureus: Methicillin-resistant (MRSA)11Locked
Steptococcus Mutans Infections11Locked
Streptococcus Infections11Locked
Vibrio Infections11Locked
41 Pharmacological Actions Researched for Sage
NameACCKFocus
Neuroprotective Agents727Locked
Antioxidants1218Locked
Anti-Bacterial Agents514Locked
Chemopreventive313Locked
Antifungal Agents312Locked
Acetylcholinesterase Inhibitor110Locked
Anti-Inflammatory Agents710Locked
Antiproliferative 56Locked
Hepatoprotective35Locked
Tumor Necrosis Factor (TNF) Alpha Inhibitor35Locked
Antimicrobial44Locked
Antinoceceptive 34Locked
Antiviral Agents33Locked
Apoptotic33Locked
Hypoglycemic Agents23Locked
Hypolipidemic23Locked
Anti-Anxiety Agents12Locked
Anti-Fibrotic12Locked
Antidepressive Agents12Locked
Antineoplastic Agents12Locked
Cytoprotective12Locked
Cytotoxic22Locked
Genoprotective12Locked
Gluconeogenesis Inhibitor12Locked
Insulin Sensitizers12Locked
Interleukin-10 upregulation12Locked
Interleukin-12 downregulation12Locked
Interleukin-2 upregulation12Locked
Interleukin-4 upregulation12Locked
Superoxide Dismutase Up-regulation12Locked
Air Pollutants: Radioactive11Locked
Analgesics11Locked
Antimutagenic Agents11Locked
Benzodiazepine receptor agonist11Locked
Cell cycle arrest11Locked
Cholinesterase Inhibitors11Locked
Insecticidal11Locked
Interleukin-1 beta downregulation11Locked
Photoprotective11Locked
Photosensitizing Agents11Locked
Proton Pump Inhibitor11Locked
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View the Evidence:
67 Abstracts with Sage Research

[+]

Drinking herbal teas, especially chamomile over 30 years may significantly reduced the risk of thyroid cancer and benign thyroid diseases development by almost 80%.Apr 03, 2015

Pubmed Data : Eur J Public Health. 2015 Apr 4. Epub 2015 Apr 4. PMID: 25842380
Article Published Date : Apr 03, 2015
Study Type : Human Study
Additional Links
Substances : Chamomile, Sage
Diseases : Hyperthyroidism, Thyroid Cancer
Additional Keywords : Herbal Teas, Risk Reduction
[+]

Echinacea/sage is at least as effective as chlorhexidine/lidocaine for treating acute sore throats. Sep 01, 2009

Pubmed Data : Eur J Med Res. 2009 Sep 1;14(9):406-12. PMID: 19748859
Article Published Date : Sep 01, 2009
Study Type : Human Study
Additional Links
Substances : Echinacea, Sage
Diseases : Sore Throat
Additional Keywords : Natural Substances Versus Drugs
[+]

Effectiveness of Menosan® Salvia officinalis in the treatment of a wide spectrum of menopausal complaints.Jan 31, 2021

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Heliyon. 2021 Feb ;7(2):e05910. Epub 2021 Feb 10. PMID: 33615001
Article Published Date : Jan 31, 2021
Study Type : Human Study
Additional Links
Substances : Sage
Diseases : Perimenopausal Syndrome
[+]

S. officinalis in the form of vaginal tablet, alone and when combined with Clotrimazole, can treat the Vulvovaginal Candidiasis.Mar 31, 2019

Pubmed Data : J Obstet Gynaecol Res. 2019 Apr ;45(4):897-907. Epub 2019 Jan 20. PMID: 30663184
Article Published Date : Mar 31, 2019
Study Type : Human Study
Additional Links
Substances : Sage
Diseases : Candidiasis: Vulvovaginal
Pharmacological Actions : Antifungal Agents
[+]

Sage (Salvia officinalis) extract has a therapeutic effect on patients with mild to moderate Alzheimer's disease. Feb 01, 2003

Pubmed Data : J Clin Pharm Ther. 2003 Feb;28(1):53-9. PMID: 12605619
Article Published Date : Feb 01, 2003
Study Type : Human Study
Additional Links
Substances : Sage
Diseases : Alzheimer's Disease
Additional Keywords : Plant Extracts
[+]

Sage and alfalfa extracts are effective in reducing menopausal symptoms.May 01, 1998

Pubmed Data : Minerva Ginecol. 1998 May;50(5):207-11. PMID: 9677811
Article Published Date : May 01, 1998
Study Type : Human Study
Additional Links
Substances : Alfalfa, Sage
Diseases : Hot Flash, Menopausal Syndrome
[+]

Sage extract is as effective as hydrocortisone in the topical treatment of erythema.Sep 01, 2007

Pubmed Data : Planta Med. 2007 Sep;73(11):1190-1. Epub 2007 Aug 23. PMID: 17713873
Article Published Date : Sep 01, 2007
Study Type : Human Study
Additional Links
Substances : Sage
Diseases : Erythema
Additional Keywords : Natural Substances Versus Drugs
[+]

Sage has cholinesterase inhibiting properties which improve mood and cognitive performance.Apr 01, 2006

Pubmed Data : Neuropsychopharmacology. 2006 Apr;31(4):845-52. PMID: 16205785
Article Published Date : Apr 01, 2006
Study Type : Human Study
Additional Links
Substances : Sage
Diseases : Cognitive Decline/Dysfunction, Mood Disorders
Pharmacological Actions : Acetylcholinesterase Inhibitor
[+]

Sage spray is a safe and effective treatment for patients with acute pharyngitis. Jan 31, 2006

Pubmed Data : Eur J Med Res. 2006 Jan 31;11(1):20-6. PMID: 16504956
Article Published Date : Jan 31, 2006
Study Type : Human Study
Additional Links
Substances : Sage
Diseases : Pharyngeal Diseases, Pharyngitis
[+]

Salvia officinalis is an effective alternative agent to reduce the severity of psychological and physical symptoms of PMS.Dec 31, 2018

Pubmed Data : Complement Med Res. 2019 ;26(1):39-46. Epub 2018 Dec 15. PMID: 30572339
Article Published Date : Dec 31, 2018
Study Type : Human Study
Additional Links
Substances : Sage
Diseases : Premenstrual syndrome
[+]

The acute and chronic cognitive effects of a sage extract.Jan 13, 2021

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Nutrients. 2021 Jan 14 ;13(1). Epub 2021 Jan 14. PMID: 33466627
Article Published Date : Jan 13, 2021
Study Type : Human Study
Additional Links
Substances : Sage
Diseases : Cognitive Decline/Dysfunction
Pharmacological Actions : Neuroprotective Agents
[+]

The protective effect of the Mediterranean diet on lung cancer.Dec 31, 2002

Pubmed Data : Nutr Cancer. 2003 ;46(1):30-7. PMID: 12925301
Article Published Date : Dec 31, 2002
Study Type : Human Study
Additional Links
Substances : Olive Oil, Sage
Diseases : Lung Cancer, Smoking
Therapeutic Actions : Dietary Modification: Mediterranean Diet
Pharmacological Actions : Chemopreventive
[+]

The Sage mouthwash effectively reduced the number of Streptococcus mutans in dental plaque.May 31, 2015

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Iran J Microbiol. 2015 Jun ;7(3):173-7. PMID: 26668706
Article Published Date : May 31, 2015
Study Type : Human Study
Additional Links
Substances : Sage
Diseases : Dental Plaque
Pharmacological Actions : Anti-Bacterial Agents
[+]

The spice sage and its active, neuroprotective ingredient rosmarinic acid could validate the traditional use of this spice in the treatment of Alzheimer's disease. Jun 01, 2006

Pubmed Data : J Pharmacol Exp Ther. 2006 Jun;317(3):1143-9. Epub 2006 Feb 22. PMID: 16495207
Article Published Date : Jun 01, 2006
Study Type : Human Study
Additional Links
Substances : Sage
Diseases : Alzheimer's Disease
Pharmacological Actions : Neuroprotective Agents
Additional Keywords : Confirm
[+]

The study design proved a simple cost effective trial protocol to test the efficacy of herbal medicines on verbal episodic memory.Jan 14, 2018

Pubmed Data : Phytomedicine. 2018 Jan 15 ;39:42-48. Epub 2017 Aug 18. PMID: 29433682
Article Published Date : Jan 14, 2018
Study Type : Human Study
Additional Links
Substances : Lemon Balm, Rosemary, Sage
Diseases : Alzheimer's Disease, Dementia
Pharmacological Actions : Neuroprotective Agents
Additional Keywords : Plant Extracts, Risk Reduction
[+]

Women treated with a fresh sage preparation experienced a significant decrease in the number and severity of hot flashes over an eight-week study period.Jun 01, 2011

Pubmed Data : Adv Ther. 2011 Jun ;28(6):490-500. Epub 2011 May 16. PMID: 21630133
Article Published Date : Jun 01, 2011
Study Type : Human Study
Additional Links
Substances : Sage
Diseases : Hot Flash
Additional Keywords : Phytotherapy, Plant Extracts
[+]

Bioactive phytochemicals from Salvia officinalis attenuate cadmium-induced oxidative damage and genotoxicity.Jul 16, 2021

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Environ Sci Pollut Res Int. 2021 Jul 17. Epub 2021 Jul 17. PMID: 34275073
Article Published Date : Jul 16, 2021
Study Type : Animal Study
Additional Links
Substances : Sage
Diseases : Cadmium Poisoning
Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants, Tumor Necrosis Factor (TNF) Alpha Inhibitor
Problem Substances : Cadmium
[+]

Cirsiliol could inhibit esophageal squamous cell carcinoma by suppression of TYK2.Mar 16, 2021

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : J Exp Clin Cancer Res. 2021 Mar 17 ;40(1):105. Epub 2021 Mar 17. PMID: 33731185
Article Published Date : Mar 16, 2021
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Sage
Diseases : Esophageal Cancer, Squamous cell carcinoma
Pharmacological Actions : Antiproliferative
[+]

Consumption of Sage and Thyme extracts positively affects the resistance of rat liver cells against oxidative stress.Dec 31, 2015

Pubmed Data : Mutagenesis. 2016 Jan ;31(1):51-9. Epub 2015 Aug 21. PMID: 26297740
Article Published Date : Dec 31, 2015
Study Type : Animal Study
Additional Links
Substances : Sage, Thyme
Diseases : Liver Disease: Oxidative Stress, Oxidative Stress
Pharmacological Actions : Antioxidants, Hepatoprotective
[+]

Effect of Salvia Officinalis L. and Rosmarinus Officinalis L. leaves extracts on anxiety and neural activity.Dec 31, 2018

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Bioinformation. 2019 ;15(3):172-178. Epub 2019 Mar 15. PMID: 31354192
Article Published Date : Dec 31, 2018
Study Type : Animal Study
Additional Links
Substances : Rosemary, Sage
Diseases : Anxiety, Depression
Pharmacological Actions : Anti-Anxiety Agents, Antidepressive Agents
[+]

Manool, a diterpene from Salvia officinalis, exerts preventive effects on chromosomal damage and pre-neoplastic lesions.Jan 28, 2021

Pubmed Data : Mutagenesis. 2021 Jan 29. Epub 2021 Jan 29. PMID: 33512444
Article Published Date : Jan 28, 2021
Study Type : Animal Study
Additional Links
Substances : Sage
Diseases : Preneoplastic Conditions
Pharmacological Actions : Antineoplastic Agents
[+]

S. officinalis has been observed to have useful effects on LPS-induced inflammation and oxidative stress.Nov 30, 2017

Pubmed Data : J Med Food. 2017 Dec ;20(12):1193-1200. Epub 2017 Nov 13. PMID: 29131698
Article Published Date : Nov 30, 2017
Study Type : Animal Study
Additional Links
Substances : Sage
Diseases : Lipopolysaccharide-Induced Toxicity, Oxidative Stress
Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

Sage essential oil can modulate genetic damage and histological alteration induced by carbon tetrachloride in the testes.Nov 02, 2017

Pubmed Data : Environ Sci Pollut Res Int. 2017 Nov 3. Epub 2017 Nov 3. PMID: 29098592
Article Published Date : Nov 02, 2017
Study Type : Animal Study
Additional Links
Substances : Sage
Diseases : Testicular Injury: Chemical/Metal Induced
Pharmacological Actions : Cytoprotective
[+]

Sage essential oil is a potential candidate for counteracting hepatic injury associating Co-amoxiclav.May 31, 2016

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Int J Biomed Sci. 2016 Jun ;12(2):71-8. PMID: 27493593
Article Published Date : May 31, 2016
Study Type : Animal Study
Additional Links
Substances : Sage
Diseases : Liver Damage: Drug-Induced
Pharmacological Actions : Hepatoprotective
Additional Keywords : Essential Oils
[+]

Sage extract at low dose exhibits similar effects to rosiglitazone.Dec 31, 2017

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : PeerJ. 2018 ;6:e4166. Epub 2018 Jan 9. PMID: 29333341
Article Published Date : Dec 31, 2017
Study Type : Animal Study
Additional Links
Substances : Sage
Diseases : High Fat Diet, Insulin Resistance, Obesity
Pharmacological Actions : Anti-Inflammatory Agents, Insulin Sensitizers, Interleukin-10 upregulation, Interleukin-12 downregulation, Interleukin-2 upregulation, Interleukin-4 upregulation, Tumor Necrosis Factor (TNF) Alpha Inhibitor
Additional Keywords : Natural Substances Versus Drugs
[+]

Sage leaf extract may be an effective treatment for type 2 diabetes.Aug 01, 2006

Pubmed Data : Br J Nutr. 2006 Aug;96(2):326-33. PMID: 16923227
Article Published Date : Aug 01, 2006
Study Type : Animal Study
Additional Links
Substances : Sage
Diseases : Diabetes Mellitus: Type 2
Pharmacological Actions : Gluconeogenesis Inhibitor
Additional Keywords : Drug: Metformin, Metformin Alternatives
[+]

Sage leaves, used as medicinal plant, exerted its beneficial effects in the management of menopause disorders.Oct 28, 2020

Pubmed Data : J Food Biochem. 2020 Oct 29:e13542. Epub 2020 Oct 29. PMID: 33124046
Article Published Date : Oct 28, 2020
Study Type : Animal Study
Additional Links
Substances : Sage
Diseases : Postmenopausal Disorders
Pharmacological Actions : Antioxidants, Hepatoprotective
Additional Keywords : Anti-Obesity Agents
[+]

Sage promotes alveologenesis of mammary glands and it can be used as a lactiferous herb.Oct 31, 2015

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Avicenna J Phytomed. 2015 Nov-Dec;5(6):560-7. PMID: 26693413
Article Published Date : Oct 31, 2015
Study Type : Animal Study
Additional Links
Substances : Sage
[+]

Sage tea consumption may influence the oxidative status and reduce the blood glucose and atherogenic index in PCOS women.Apr 30, 2020

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Avicenna J Phytomed. 2020 May-Jun;10(3):263-272. PMID: 32523881
Article Published Date : Apr 30, 2020
Study Type : Animal Study
Additional Links
Substances : Sage
Diseases : Oxidative Stress, Polycystic Ovary Syndrome
Pharmacological Actions : Antioxidants, Hypoglycemic Agents
[+]

Sage, Salvia officinalis L., constituents, hepatoprotective activity, and cytotoxicity evaluations of the essential oils.Sep 22, 2021

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Molecules. 2021 Sep 23 ;26(19). Epub 2021 Sep 23. PMID: 34641301
Article Published Date : Sep 22, 2021
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Sage
Diseases : Acetaminophen (Tylenol) Toxicity , Breast Cancer, Cervical Cancer, Liver Cancer
Pharmacological Actions : Antioxidants, Antiproliferative , Hepatoprotective, Malondialdehyde Down-regulation
Problem Substances : Acetaminophen
[+]

Salvia officinalis and its principal constituent rosmarinic acid represent a potential therapeutic option against diabetic memory impairment.Apr 21, 2016

Pubmed Data : Neurosci Lett. 2016 Apr 22 ;622:72-77. Epub 2016 Apr 22. PMID: 27113201
Article Published Date : Apr 21, 2016
Study Type : Animal Study
Additional Links
Substances : Rosmarinic acid, Sage
Diseases : Diabetes: Memory Problems
Pharmacological Actions : Antioxidants, Neuroprotective Agents, Superoxide Dismutase Up-regulation
[+]

Salvia officinalis attenuates bleomycin-induced oxidative stress and lung fibrosis in rats.Oct 11, 2019

Pubmed Data : Nutr Cancer. 2019 Oct 12:1-11. Epub 2019 Oct 12. PMID: 31608667
Article Published Date : Oct 11, 2019
Study Type : Animal Study
Additional Links
Substances : Sage
Diseases : Oxidative Stress, Pulmonary Fibrosis: Bleomycin-Induced
Pharmacological Actions : Anti-Fibrotic, Antioxidants
[+]

Salvia officinalis has antinociceptive effects and may decrease tolerance and dependence induced by repeated morphine administration.Dec 31, 2014

Pubmed Data : Am J Drug Alcohol Abuse. 2015 ;41(5):405-13. PMID: 26337199
Article Published Date : Dec 31, 2014
Study Type : Animal Study
Additional Links
Substances : Sage
Diseases : Morphine Tolerance/Dependence
Pharmacological Actions : Antinoceceptive
[+]

Salvia officinalis, rosmarinic and caffeic acids attenuate neuropathic pain and improve function recovery after sciatic nerve chronic constriction.Dec 31, 2018

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Evid Based Complement Alternat Med. 2019 ;2019:1702378. Epub 2019 Jun 24. PMID: 31341489
Article Published Date : Dec 31, 2018
Study Type : Animal Study
Additional Links
Substances : Carnosic Acid, Rosmarinic acid, Sage
Diseases : Neuropathic Pain, Sciatic Nerve Crush Injury
Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants, Neuroprotective Agents
[+]

The protective effects of Salvia officinalis essential oil compared to simvastatin against hyperlipidemia.Feb 02, 2020

Pubmed Data : J Food Biochem. 2020 Feb 3:e13160. Epub 2020 Feb 3. PMID: 32010989
Article Published Date : Feb 02, 2020
Study Type : Animal Study
Additional Links
Substances : Sage
Diseases : High Fat Diet, Hyperlipidemia
Pharmacological Actions : Hypolipidemic
Additional Keywords : Superiority of Natural Substances versus Drugs
Problem Substances : Simvastatin
[+]

These results confirms in vivo the chemopreventive effects of S. officinalis.Jan 31, 2016

Pubmed Data : Phytother Res. 2016 Feb ;30(2):298-305. Epub 2015 Dec 14. PMID: 26661587
Article Published Date : Jan 31, 2016
Study Type : Animal Study
Additional Links
Substances : Sage
Diseases : Colon Cancer
Pharmacological Actions : Antiproliferative , Chemopreventive, Genoprotective
[+]

A combination of plant extracts could induce antiproliferative and apoptosis in acute myeloid leukemia cells.May 06, 2016

Pubmed Data : Biomed Pharmacother. 2016 May 7 ;82:80-89. Epub 2016 May 7. PMID: 27470342
Article Published Date : May 06, 2016
Study Type : In Vitro Study
Additional Links
Substances : Oregano, Rose , Rose Hips, Sage, Sea buckthorn, Vitamin D
Diseases : Acute Myeloid Leukemia
Pharmacological Actions : Antiproliferative , Apoptotic, Cell cycle arrest
Additional Keywords : Natural Substance Synergy, Plant Extracts
[+]

A number of plant oil extracts inhibit multi-resistant strains of bacteria and yeast. May 25, 2009

Pubmed Data : J Craniomaxillofac Surg. 2009 May 25. PMID: 19473851
Article Published Date : May 25, 2009
Study Type : In Vitro Study
Additional Links
Substances : Cinnamon, Clove, Grapefruit, Lemongrass, Peppermint, Sage, Sandalwood, Thyme
Diseases : Candida Infection , MRSA, Staphylococcus aureus: Methicillin-resistant (MRSA)
Pharmacological Actions : Anti-Bacterial Agents, Antifungal Agents
[+]

A review of medicinal herbs in the treatment of neuropathic pain.Mar 31, 2018

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Iran J Basic Med Sci. 2018 Apr ;21(4):347-358. PMID: 29796216
Article Published Date : Mar 31, 2018
Study Type : Review
Additional Links
Substances : Acorus calamus, Bitter Apple, Bitter Melon, Ginkgo biloba, Holy Basil, Kratom, Olive, Palash, Phyllanthus amarus , Saffron, Sage, Tarragon, Turmeric
Diseases : Neuropathic Pain
Pharmacological Actions : Analgesics, Antinoceceptive
[+]

A review of the potential cognitive-enhancing and protective effects of sage. Feb 28, 2017

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Drugs R D. 2017 Mar ;17(1):53-64. PMID: 27888449
Article Published Date : Feb 28, 2017
Study Type : Review
Additional Links
Substances : Sage
Diseases : Neurodegenerative Diseases
Pharmacological Actions : Neuroprotective Agents
Additional Keywords : Plant Extracts
[+]

Analyses of putative anti-cancer potential of three STAT3 signaling inhibitory compounds derived from Salvia officinalis.Feb 28, 2021

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Biochem Biophys Rep. 2021 Mar ;25:100882. Epub 2020 Dec 24. PMID: 33392396
Article Published Date : Feb 28, 2021
Study Type : In Vitro Study
Additional Links
Substances : Sage
Diseases : Cancers: All
Pharmacological Actions : Antiproliferative , Immunomodulatory, STAT3 Inhibitor
[+]

Antimicrobial activity of noncytotoxic concentrations of Salvia officinalis extract against bacterial and fungal species from the oral cavity.Dec 31, 2018

Pubmed Data : Gen Dent. 2019 Jan-Feb;67(1):22-26. PMID: 30644826
Article Published Date : Dec 31, 2018
Study Type : In Vitro Study
Additional Links
Substances : Sage
Diseases : Candida Infection , Steptococcus Mutans Infections
Pharmacological Actions : Anti-Inflammatory Agents, Antimicrobial, Interleukin-1 beta downregulation, Tumor Necrosis Factor (TNF) Alpha Inhibitor
Additional Keywords : Plant Extracts
[+]

Antioxidant and anti-inflammatory activities of cytocompatible Salvia officinalis extractsNov 19, 2020

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Antioxidants (Basel). 2020 Nov 20 ;9(11). Epub 2020 Nov 20. PMID: 33233648
Article Published Date : Nov 19, 2020
Study Type : In Vitro Study
Additional Links
Substances : Sage
Diseases : Inflammation
Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants, Interleukin-6 Downregulation, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

Aqueous extracts from peppermint, sage and lemon balm leaves exhibit anti-HIV-1 activity.Mar 20, 2008

Pubmed Data : Retrovirology. 2008 Mar 20;5:27. PMID: 18355409
Article Published Date : Mar 20, 2008
Study Type : In Vitro Study
Additional Links
Substances : Lemon Balm, Peppermint, Sage
Diseases : HIV Infections
Pharmacological Actions : Antiviral Agents
[+]

Basil and sage essential oils are potentially highly efficient antipseudomonal agents.Jun 30, 2020

Pubmed Data : Food Chem Toxicol. 2020 Jul ;141:111431. Epub 2020 May 14. PMID: 32417365
Article Published Date : Jun 30, 2020
Study Type : In Vitro Study
Additional Links
Substances : Basil, Sage
Diseases : Pseudomonas aeruginosa
Pharmacological Actions : Anti-Bacterial Agents
Additional Keywords : Essential Oils
[+]

Brazilian Salvia officinalis used as condiment and tea may protect the body against some disease.Feb 01, 2016

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : An Acad Bras Cienc. 2016 Feb 2. Epub 2016 Feb 2. PMID: 26839997
Article Published Date : Feb 01, 2016
Study Type : In Vitro Study
Additional Links
Substances : Sage
Diseases : Cervical Cancer, Colon Cancer, Inflammation, Kidney Cancer, Lung Cancer, Malignant Melanoma, Oxidative Stress
Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants, Apoptotic, Chemopreventive
Additional Keywords : Selective Cytotoxicity
[+]

Chemical composition and biological activities of Salvia officinalis essential oil from Tunisia.Dec 31, 2016

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : EXCLI J. 2017 ;16:160-173. Epub 2017 Mar 6. PMID: 28507464
Article Published Date : Dec 31, 2016
Study Type : In Vitro Study
Additional Links
Substances : Sage
Pharmacological Actions : Antimicrobial, Antioxidants, Insecticidal
Additional Keywords : Essential Oils
[+]

Cirsiliol may be considered a promising compound against EMT in the therapeutic management of malignant melanoma.Jan 30, 2019

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Int J Mol Sci. 2019 Jan 31 ;20(3). Epub 2019 Jan 31. PMID: 30708951
Article Published Date : Jan 30, 2019
Study Type : In Vitro Study
Additional Links
Substances : Sage
Diseases : Malignant Melanoma, Skin Cancer
Pharmacological Actions : Anti-Inflammatory Agents, Anti-metastatic, Chemotherapeutic, Matrix metalloproteinase-9 (MMP-9) inhibitor, NF-kappaB Inhibitor
[+]

Essential oils from Origanum vulgare and Salvia officinalis exhibit antibacterial and anti-biofilm activities against Streptococcus pyogenes.Feb 12, 2018

Pubmed Data : Microb Pathog. 2018 Feb 13 ;117:118-127. Epub 2018 Feb 13. PMID: 29452197
Article Published Date : Feb 12, 2018
Study Type : In Vitro Study
Additional Links
Substances : Oregano, Sage
Diseases : Streptococcus Infections
Pharmacological Actions : Antimicrobial
Additional Keywords : Essential Oils
[+]

Extracts from herb species can significantly inhibit the growth of human colon cancer cells.Aug 14, 2011

Pubmed Data : J Sci Food Agric. 2011 Aug 15 ;91(10):1849-54. Epub 2011 Mar 30. PMID: 21452174
Article Published Date : Aug 14, 2011
Study Type : In Vitro Study
Additional Links
Substances : Peppermint, Rosemary, Sage, Spearmint, Thyme
Diseases : Colon Cancer
Pharmacological Actions : Antiproliferative
Additional Keywords : Phytotherapy, Plant Extracts
[+]

Extracts from plants in the Lamiacea family inhibit HSV-1, HSV-2 and acyclovir-resistant strains of HSV-1. Dec 01, 2006

Pubmed Data : Planta Med. 2006 Dec;72(15):1378-82. Epub 2006 Nov 7. PMID: 17091431
Article Published Date : Dec 01, 2006
Study Type : In Vitro Study
Additional Links
Substances : Heal-All, Lemon Balm, Peppermint, Rosemary, Sage, Thyme
Diseases : Herpes family viruses, HSV-1, HSV-2
Pharmacological Actions : Antiviral Agents
Additional Keywords : Acylcovir-Resistance, Superiority of Natural Substances versus Drugs
[+]

In vitro inhibitory effects of cirsiliol on IL-6-induced STAT3 activation through anti-inflammatory activity.Dec 31, 2018

Pubmed Data : Bioorg Med Chem Lett. 2019 07 1 ;29(13):1586-1592. Epub 2019 May 2. PMID: 31060888
Article Published Date : Dec 31, 2018
Study Type : In Vitro Study
Additional Links
Substances : Sage
Diseases : Inflammation
Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-6 Downregulation, STAT3 Inhibitor
[+]

Manool, a Salvia officinalis diterpene, induces selective cytotoxicity in cancer cells.Nov 06, 2015

Pubmed Data : Cytotechnology. 2015 Nov 7. Epub 2015 Nov 7. PMID: 26547581
Article Published Date : Nov 06, 2015
Study Type : In Vitro Study
Additional Links
Substances : Sage
Diseases : Breast Cancer, Cervical Cancer, Glioblastoma, Liver Cancer, Melanoma
Pharmacological Actions : Cytotoxic
Additional Keywords : Selective Cytotoxicity
[+]

Pharmacological properties of Salvia officinalis and its components.Sep 30, 2017

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : J Tradit Complement Med. 2017 Oct ;7(4):433-440. Epub 2017 Jan 13. PMID: 29034191
Article Published Date : Sep 30, 2017
Study Type : Review
Additional Links
Substances : Sage
Pharmacological Actions : Anti-Inflammatory Agents, Antimicrobial, Antimutagenic Agents, Antinoceceptive , Antioxidants, Hypoglycemic Agents, Hypolipidemic, Neuroprotective Agents
[+]

Potential benefits of phytochemicals against Alzheimer's disease.Jan 31, 2017

Pubmed Data : Proc Nutr Soc. 2017 Feb 1:1-7. Epub 2017 Feb 1. PMID: 28143625
Article Published Date : Jan 31, 2017
Study Type : Review
Additional Links
Substances : Ginkgo biloba, Ginseng, Lemon Balm, Resveratrol, Sage
Diseases : Alzheimer's Disease
Pharmacological Actions : Anti-Inflammatory Agents, Cholinesterase Inhibitors, Neuroprotective Agents
[+]

Rosmarinus officinalis L. and Salvia officinalis L. were found to have an antitumoral activity.Mar 30, 2020

Pubmed Data : J Complement Integr Med. 2020 Mar 31. Epub 2020 Mar 31. PMID: 32229691
Article Published Date : Mar 30, 2020
Study Type : In Vitro Study
Additional Links
Substances : Rosemary, Sage
Diseases : Glioblastoma
Pharmacological Actions : Antioxidants, Cytotoxic
Additional Keywords : Selective Cytotoxicity
[+]

Sage contains antioxidant and hepatoprotective properties.Feb 28, 2005

Pubmed Data : J Ethnopharmacol. 2005 Feb 28;97(2):383-9. Epub 2005 Jan 17. PMID: 15707779
Article Published Date : Feb 28, 2005
Study Type : In Vitro Study
Additional Links
Substances : Sage
Pharmacological Actions : Antioxidants, Hepatoprotective
[+]

Sage contains compounds which bind to the benzodiazepine receptor in the human brain. Feb 01, 2003

Pubmed Data : Planta Med. 2003 Feb;69(2):113-7. PMID: 12624814
Article Published Date : Feb 01, 2003
Study Type : In Vitro Study
Additional Links
Substances : Sage
Pharmacological Actions : Benzodiazepine receptor agonist
Additional Keywords : Plant Extracts
[+]

Sage has gastroprotective compounds which exhibit proton and potassium pump inhibitory activity. Oct 01, 2009

Pubmed Data : Fitoterapia. 2009 Oct;80(7):421-6. Epub 2009 May 28. PMID: 19481590
Article Published Date : Oct 01, 2009
Study Type : In Vitro Study
Additional Links
Substances : Sage
Diseases : Alcohol Toxicity , Gastric Ulcer
Pharmacological Actions : Proton Pump Inhibitor
Additional Keywords : Plant Extracts
[+]

Sage may prevent degenerative diseases associated with oxidative stress. Mar 01, 2007

Pubmed Data : Pediatr Neurol. 2007 Mar;36(3):152-8. PMID: 19298199
Article Published Date : Mar 01, 2007
Study Type : In Vitro Study
Additional Links
Substances : Sage
Diseases : Oxidative Stress
Pharmacological Actions : Air Pollutants: Radioactive, Antioxidants
Additional Keywords : Plant Extracts
[+]

Tarragon, sweet basil, sage and sweet acacia have anti-Vibrio cholerae activity.Aug 27, 2010

Pubmed Data : Appl Environ Microbiol. 2010 Aug 27. Epub 2010 Aug 27. PMID: 20802077
Article Published Date : Aug 27, 2010
Study Type : In Vitro Study
Additional Links
Substances : Basil, Basil: Sweet, Sage, Sweet Acacia, Tarragon
Diseases : Cholera, Vibrio Infections
Pharmacological Actions : Antiviral Agents
[+]

Tea extracts facilitated free radical production in leukemia cells but protected normal cells from UV radiation. May 12, 2015

Pubmed Data : Int J Radiat Biol. 2015 May 13:1-24. Epub 2015 May 13. PMID: 25968555
Article Published Date : May 12, 2015
Study Type : In Vitro Study
Additional Links
Substances : Black Tea, Green Tea, Rose Hips, Sage
Diseases : Leukemia
Pharmacological Actions : Photoprotective, Photosensitizing Agents
Additional Keywords : Plant Extracts
[+]

Therapeutic properties of several chemical compounds from Salvia officinalis L. in Alzheimer's disease.Dec 29, 2020

Pubmed Data : Mini Rev Med Chem. 2020 Dec 30. Epub 2020 Dec 30. PMID: 33390133
Article Published Date : Dec 29, 2020
Study Type : Review
Additional Links
Substances : Sage
Diseases : Alzheimer's Disease
Pharmacological Actions : Neuroprotective Agents
[+]

These results showed the high potential of sage and basil oils for the treatment of persistent infections caused by P. aeruginosa biofilms.Aug 28, 2016

Pubmed Data : Cell Mol Biol (Noisy-le-grand). 2016 Aug 29 ;62(9):27-33. Epub 2016 Aug 29. PMID: 27585258
Article Published Date : Aug 28, 2016
Study Type : In Vitro Study
Additional Links
Substances : Basil, Sage
Diseases : Pseudomonas aeruginosa
Pharmacological Actions : Anti-Bacterial Agents
Additional Keywords : Biofilm, Plant Oils
[+]

This paper reviews classical methods for evaluating antibacterial and antifungal activity of essential oils and gives an overview on the susceptibility of human and food-borne bacteria and fungi towards different essential oils and their constituents.May 01, 2003

Pubmed Data : Curr Med Chem. 2003 May ;10(10):813-29. PMID: 12678685
Article Published Date : May 01, 2003
Study Type : Review
Additional Links
Substances : Cinnamon, Mint, Oregano, Sage, Thyme
Diseases : Foodborne Pathogens: Prevention/Food Preservation
Pharmacological Actions : Anti-Bacterial Agents, Antifungal Agents
[+]

This study shows the potential of sage extracts to be used in the prevention or treatment of liver cancer.Dec 04, 2016

Pubmed Data : Biomed Pharmacother. 2016 Dec 5 ;85:57-67. Epub 2016 Dec 5. PMID: 27930987
Article Published Date : Dec 04, 2016
Study Type : In Vitro Study
Additional Links
Substances : Red Sage, Sage
Diseases : Liver Cancer
Pharmacological Actions : Antiproliferative , Apoptotic
Additional Keywords : Dose Response, Plant Extracts
[+]

Thyme and sage essential oils exhibited in vitro anti-proliferative activity on two melanoma cell lines.Jan 15, 2018

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Molecules. 2018 Jan 16 ;23(1). Epub 2018 Jan 16. PMID: 29337923
Article Published Date : Jan 15, 2018
Study Type : In Vitro Study
Additional Links
Substances : Sage, Thyme
Diseases : Melanoma
Pharmacological Actions : Antiproliferative
Additional Keywords : Natural Substance Synergy

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