Tannic Acid

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29 Diseases Researched for Tannic Acid
NameACCKFocus
Gastric Ulcer23Locked
Cardiac Hypertrophy12Locked
Cardiovascular Diseases12Locked
Chemically-Induced Liver Damage12Locked
Chemotherapy-Induced Toxicity: Cisplatin12Locked
Chemotherapy-Induced Toxicity: Doxorubicin12Locked
Colon Cancer22Locked
Endothelial Dysfunction12Locked
Food Allergies12Locked
HIV Infections22Locked
Hypertension12Locked
Kidney Failure12Locked
Prostate Cancer22Locked
Snake Bite: Venom Toxicity 12Locked
Staphylococcus aureus infection22Locked
Acid Reflux11Locked
Advanced Glycation End products (AGE)11Locked
Alzheimer's Disease11Locked
Bacterial Infections and Mycoses11Locked
Breast Cancer11Locked
Diabetes Mellitus: Type 2: Prevention11Locked
Dysbiosis11Locked
Excitotoxicity 11Locked
Glioma11Locked
Infection: Antibiotic Resistant11Locked
Lipid Peroxidation11Locked
Norovirus11Locked
Oral Cancer11Locked
Staphylococcus aureus: Methicillin-resistant (MRSA)11Locked
29 Pharmacological Actions Researched for Tannic Acid
NameACCKFocus
Antioxidants813Locked
Anti-Apoptotic24Locked
Cardioprotective24Locked
Anti-Ulcer Agents23Locked
Antiproliferative 33Locked
Antiviral Agents33Locked
Apoptotic33Locked
Anti-Fibrotic12Locked
Anti-Inflammatory Agents12Locked
Anticarcinogenic Agents22Locked
Antihypertensive Agents12Locked
Chemoprotective Agents12Locked
Enzyme Inhibitors12Locked
Hepatoprotective12Locked
Interleukin-1 beta downregulation12Locked
NF-kappaB Inhibitor12Locked
Tumor Necrosis Factor (TNF) Alpha Inhibitor12Locked
Vasodilator Agents12Locked
Vasoprotective12Locked
Anti-Bacterial Agents11Locked
Anti-metastatic11Locked
Antimicrobial11Locked
Cell cycle arrest11Locked
Matrix Metalloproteinases Inhibitors11Locked
MicroRNA modulator11Locked
Neuroprotective Agents11Locked
Nitric Oxide Inhibitor11Locked
Proton Pump Inhibitor11Locked
Tumor Suppressor Protein p53 Upregulation11Locked

View the Evidence:
41 Abstracts with Tannic Acid Research

[+]

Persimmon fruit tannin-rich fiber reduces cholesterol levels in humans.Dec 31, 2012

Pubmed Data : Ann Nutr Metab. 2013 ;62(1):1-6. Epub 2012 Nov 17. PMID: 23171573
Article Published Date : Dec 31, 2012
Study Type : Human Study
Additional Links
Substances : Fiber, Persimmon , Tannic Acid
Diseases : High Cholesterol, Hypercholesterolemia
Pharmacological Actions : Anticholesteremic Agents
Additional Keywords : Plant Extracts
[+]

1,3,4-tri-O-galloyl-6-O-caffeoyl-β-D-glucopyranose, a New Anti-Proliferative Ellagitannin, Regulates the Expression of microRNAs in HepG(2) Cancer Cells.Oct 01, 2011

Pubmed Data : Nan Fang Yi Ke Da Xue Xue Bao. 2011 Oct ;31(10):1641-8. PMID: 22027761
Article Published Date : Oct 01, 2011
Study Type : Human In Vitro
Additional Links
Substances : Polyphenols, Tannic Acid
Diseases : Cancers
Pharmacological Actions : Antineoplastic Agents, Antiproliferative , Apoptotic
[+]

Chebulagic acid and Chebulinic acid inhibit TGF-β1 induced fibrotic changes in the chorio-retinal endothelial cells by inhibiting ERK phosphorylation.Jan 01, 2019

Pubmed Data : Microvasc Res. 2019 01 ;121:14-23. Epub 2018 Sep 4. PMID: 30189210
Article Published Date : Jan 01, 2019
Study Type : Human In Vitro
Additional Links
Substances : Tannic Acid, Triphala
Diseases : Fibrosis
Pharmacological Actions : Anti-Fibrotic
Additional Keywords : Plant Extracts
[+]

Depsidic gallotannins and simpler galloylated glucose derivatives all inhibit amyloid β-peptide (Aβ) aggregation in vitro, and monogalloylated α-glucogallin and a natural β-hexagalloylglucose are shown to be the strongest inhibitors.Jul 06, 2015

Pubmed Data : Angew Chem Int Ed Engl. 2015 Jul 6 ;54(28):8217-21. Epub 2015 May 26. PMID: 26013280
Article Published Date : Jul 06, 2015
Study Type : Human In Vitro
Additional Links
Substances : Polyphenols, Tannic Acid
Pharmacological Actions : Neuroprotective Agents
[+]

Dietary unripe apple polyphenol inhibits the development of food allergies in the mouse model. Aug 15, 2005

Pubmed Data : FEBS Lett. 2005 Aug 15;579(20):4485-91. PMID: 16081068
Article Published Date : Aug 15, 2005
Study Type : Animal Study
Additional Links
Substances : Apples, Flavonoids, Polyphenols, Tannic Acid
Diseases : Food Allergies
Additional Keywords : Proanthocyanidins
[+]

Extracts of Geum japonicum may have potential use as new anti-hypertensive agents for lowering arterial blood pressure in hypertensive patients.Jan 02, 2007

Pubmed Data : J Ethnopharmacol. 2007 Jan 3 ;109(1):128-33. Epub 2006 Jul 21. PMID: 16939706
Article Published Date : Jan 02, 2007
Study Type : Animal Study
Additional Links
Substances : Geum japonicum , Tannic Acid
Diseases : Endothelial Dysfunction, Hypertension
Pharmacological Actions : Antihypertensive Agents, Enzyme Inhibitors, Vasodilator Agents
Additional Keywords : Plant Extracts
[+]

Grean tea is effective in reducing oxidative stress and lesions associated with chronic renal failure. Jun 01, 1996

Pubmed Data : Biosci Biotechnol Biochem. 1996 Jun;60(6):1000-5. PMID: 8695898
Article Published Date : Jun 01, 1996
Study Type : Animal Study
Additional Links
Substances : Green Tea, Tannic Acid
Diseases : Kidney Failure
Pharmacological Actions : Antioxidants
[+]

Green tea tannin eliminates oxidative stress and is beneficial to renal function in cisplatin-induced nephropathy in rats. Nov 01, 1999

Pubmed Data : J Pharm Pharmacol. 1999 Nov;51(11):1325-31. PMID: 10632092
Article Published Date : Nov 01, 1999
Study Type : Animal Study
Additional Links
Substances : Green Tea, Tannic Acid
Diseases : Chemotherapy-Induced Toxicity: Cisplatin
Pharmacological Actions : Antioxidants
Additional Keywords : Antineoplastic Agents
[+]

High-salt- and cholesterol diet-associated cognitive impairment attenuated by tannins-enriched fraction of Emblica officinalis via inhibiting NF-kB pathway.Feb 01, 2018

Pubmed Data : Inflammopharmacology. 2018 Feb ;26(1):147-156. Epub 2018 Jan 15. PMID: 29335826
Article Published Date : Feb 01, 2018
Study Type : Animal Study
Additional Links
Substances : Amla Fruit, Phyllanthus emblica, Tannic Acid, Triphala
Diseases : Cognitive Decline/Dysfunction
Pharmacological Actions : Anticholesteremic Agents, Neuroprotective Agents, NF-kappaB Inhibitor
Additional Keywords : Plant Extracts
[+]

Marjoram has a protective effect on gastric mucosal injury in rats. Jan 01, 2009

Pubmed Data : Am J Chin Med. 2009;37(3):531-45. PMID: 19606513
Article Published Date : Jan 01, 2009
Study Type : Animal Study
Additional Links
Substances : Marjoram, Tannic Acid
Diseases : Gastric Ulcer
Pharmacological Actions : Anti-Ulcer Agents, Antioxidants
[+]

Plantain extract has neutralizing properties on snake venom induced toxicity.Apr 08, 2005

Pubmed Data : J Ethnopharmacol. 2005 Apr 8;98(1-2):21-9. PMID: 15763360
Article Published Date : Apr 08, 2005
Study Type : Animal Study
Additional Links
Substances : Flavonoids, Plantain, Polyphenols, Tannic Acid
Diseases : Snake Bite: Venom Toxicity
Additional Keywords : Plant Extracts
[+]

Punicalagin and ellagic acid demonstrate antimutagenic activity and inhibition of benzo[a]pyrene induced DNA adducts.Dec 31, 2013

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Biomed Res Int. 2014 ;2014:467465. Epub 2014 May 14. PMID: 24949451
Article Published Date : Dec 31, 2013
Study Type : Animal Study
Additional Links
Substances : Ellagic Acid, Pomegranate, Punicalagin, Tannic Acid
Diseases : Benzo[a]pyrene-induced Toxicity , DNA damage
Pharmacological Actions : Antimutagenic Agents, Antioxidants
Additional Keywords : Plant Extracts
Problem Substances : Benzo(a)pyrene
[+]

Tannic acid ameliorates streptozotocin -induced Alzheimer's disease-like impairment of memory.Jan 28, 2020

Pubmed Data : Neurotox Res. 2020 Jan 29. Epub 2020 Jan 29. PMID: 31997154
Article Published Date : Jan 28, 2020
Study Type : Animal Study
Additional Links
Substances : Tannic Acid
Diseases : Alzheimer's Disease, Brain Inflammation
Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-12 downregulation, Interleukin-4 downregulation, Neuroprotective Agents
Problem Substances : Streptozotocin
[+]

Tannic acid as a plant-derived polyphenol exerts vasoprotection of endothelial cells.Jul 26, 2017

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Sci Rep. 2017 Jul 27 ;7(1):6686. Epub 2017 Jul 27. PMID: 28751752
Article Published Date : Jul 26, 2017
Study Type : Animal Study
Additional Links
Substances : Tannic Acid
Diseases : Cardiovascular Diseases
Pharmacological Actions : Anti-Inflammatory Agents, Vasoprotective
[+]

Tannic acid could inhibit doxorubicin induced cardiotoxicity by inhibiting oxidative stress, inflammation and apoptotic damage.Aug 31, 2017

Pubmed Data : Biomed Pharmacother. 2017 Sep ;93:1253-1260. Epub 2017 Jul 20. PMID: 28738542
Article Published Date : Aug 31, 2017
Study Type : Animal Study
Additional Links
Substances : Tannic Acid
Diseases : Chemotherapy-Induced Toxicity: Doxorubicin
Pharmacological Actions : Anti-Apoptotic, Antioxidants, Cardioprotective, Chemoprotective Agents, Interleukin-1 beta downregulation, NF-kappaB Inhibitor, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

The cardioprotective effects of tannic acid may be attributed to multitargeted inhibition of oxidative stress, inflammation, fibrosis and apoptosis.Aug 31, 2017

Pubmed Data : J Pharm Pharmacol. 2017 Sep ;69(9):1191-1207. Epub 2017 Jun 20. PMID: 28631819
Article Published Date : Aug 31, 2017
Study Type : Animal Study
Additional Links
Substances : Tannic Acid
Diseases : Cardiac Hypertrophy
Pharmacological Actions : Anti-Apoptotic, Anti-Fibrotic, Antioxidants, Cardioprotective
[+]

The present results evidenced the beneficial effects of tannic acid and melatonin in diabetes management.Jun 30, 2019

Pubmed Data : Pak J Pharm Sci. 2019 Jul ;32(4):1453-1459. PMID: 31608862
Article Published Date : Jun 30, 2019
Study Type : Animal Study
Additional Links
Substances : Melatonin, Tannic Acid
Diseases : Diabetes Mellitus: Type 2
Pharmacological Actions : Antioxidants, Hepatoprotective
Additional Keywords : Natural Substances Versus Drugs
[+]

Walnut polyphenols prevent chemically-induced liver damage . Jun 25, 2008

Pubmed Data : J Agric Food Chem. 2008 Jun 25;56(12):4444-9. Epub 2008 May 22. PMID: 18494495
Article Published Date : Jun 25, 2008
Study Type : Animal Study
Additional Links
Substances : Flavonoids, Polyphenols, Tannic Acid, Walnut
Diseases : Chemically-Induced Liver Damage
Pharmacological Actions : Hepatoprotective
[+]

"Phlorotannins and fucoidans from marine macroalgae as matrix metalloproteinase inhibitory substances and their possible application as medicinal foods."Dec 31, 2010

Pubmed Data : Adv Food Nutr Res. 2011 ;64:129-41. PMID: 22054943
Article Published Date : Dec 31, 2010
Study Type : Review
Additional Links
Substances : Fucoidan, Phlorotannins, Seaweed, Tannic Acid
Pharmacological Actions : Matrix Metalloproteinases Inhibitors
[+]

Antivirals against chikungunya virus: Is the solution in nature?Jan 28, 2020

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Viruses. 2020 02 29 ;12(3). Epub 2020 Feb 29. PMID: 32121393
Article Published Date : Jan 28, 2020
Study Type : Review
Additional Links
Substances : Apigenin, Berberine, Chrysin, EGCG (Epigallocatechin gallate), Fisetin, Luteolin, Naringenin , Silibinin, Silymarin, Tannic Acid
Diseases : Chikungunya Virus
Pharmacological Actions : Antiviral Agents
[+]

Curcumin and tannic acid protect against glutamate-induced excitotoxicity. Aug 01, 2006

Pubmed Data : J Pharmacol Exp Ther. 2006 Aug;318(2):476-83. Epub 2006 Apr 27. PMID: 17118359
Article Published Date : Aug 01, 2006
Study Type : In Vitro Study
Additional Links
Substances : Catechin , Curcumin, Flavonoids, Polyphenols, Tannic Acid
Diseases : Excitotoxicity
Pharmacological Actions : Apoptotic, Neuroprotective Agents
[+]

Dill, fenugreek and ajwain (Trachyspermum a.) have antibacterial properties.Jan 01, 2009

Pubmed Data : BMC Complement Altern Med. 2009;9:30. Epub 2009 Aug 6. PMID: 19656417
Article Published Date : Jan 01, 2009
Study Type : In Vitro Study
Additional Links
Substances : Ajwain, Dill, Fenugreek, Flavonoids, Tannic Acid
Pharmacological Actions : Anti-Bacterial Agents
Additional Keywords : Plant Extracts
[+]

Inhibition mechanisms of hepatitis C virus infection by caffeic acid and tannic acid.Dec 31, 2018

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Biol Pharm Bull. 2019 ;42(5):770-777. PMID: 31061319
Article Published Date : Dec 31, 2018
Study Type : In Vitro Study
Additional Links
Substances : Caffeic Acid, Tannic Acid
Diseases : Hepatitis C
Pharmacological Actions : Antiviral Agents
[+]

Phytochemicals in date co-products and their antioxidant activity.Aug 31, 2014

Pubmed Data : Food Chem. 2014 Sep 1 ;158:513-20. Epub 2014 Mar 12. PMID: 24731377
Article Published Date : Aug 31, 2014
Study Type : Review
Additional Links
Substances : Anthocyanins, Carotenoids, Dates, Flavonoids, Tannic Acid
Diseases : Lipid Peroxidation
Pharmacological Actions : Antioxidants
Additional Keywords : Plant Extracts
[+]

Polyphenol-rich extracts from strawberry, arctic bramble, blackberry, and cloudberry applied to trophozoites of Giardia duodenalis were as effective as metronidazole in causing trophozoite mortality in vitro. Aug 01, 2011

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Parasitology. 2011 Aug ;138(9):1110-6. PMID: 21813029
Article Published Date : Aug 01, 2011
Study Type : In Vitro Study
Additional Links
Substances : Blackberry, Cloudberry, Flavonoids, Gallic Acid, Polyphenols, Raspberry, Strawberry, Tannic Acid
Diseases : Giardiasis
Pharmacological Actions : Antigiardial agents, Antiparasitic Agents
Additional Keywords : Antiparasitic Agents, Drug: Metronidazole, Natural Substances Versus Drugs, Plant Extracts
[+]

Pomegranate may offer an attractive dietary strategy for the prevention and treatment of AGE-related diseases such as type-2 diabetes and Alzheimer's disease.Oct 31, 2014

Pubmed Data : Food Funct. 2014 Nov ;5(11):2996-3004. PMID: 25233108
Article Published Date : Oct 31, 2014
Study Type : In Vitro Study
Additional Links
Substances : Ellagic Acid, Pomegranate, Punicalagin, Tannic Acid
Diseases : Advanced Glycation End products (AGE), Alzheimer's Disease, Diabetes Mellitus: Type 2: Prevention
Pharmacological Actions : Antioxidants
Additional Keywords : Plant Extracts
[+]

Pomegrante contains compounds with antiproliferative, apoptotic and antioxidant activites against various cancer cell lines. Jun 01, 2005

Pubmed Data : J Nutr Biochem. 2005 Jun;16(6):360-7. PMID: 15936648
Article Published Date : Jun 01, 2005
Study Type : In Vitro Study
Additional Links
Substances : Ellagic Acid, Polyphenols, Tannic Acid
Diseases : Colon Cancer, Oral Cancer, Prostate Cancer
Pharmacological Actions : Anticarcinogenic Agents, Antioxidants, Antiproliferative
Additional Keywords : Plant Extracts
[+]

Pulverized rose petals have anti-pathogenic and pre-biotic effect on intestinal flora. Mar 01, 2008

Pubmed Data : Biosci Biotechnol Biochem. 2008 Mar;72(3):773-7. Epub 2008 Mar 7. PMID: 18323655
Article Published Date : Mar 01, 2008
Study Type : In Vitro Study
Additional Links
Substances : Rose , Tannic Acid
Diseases : Bacterial Infections and Mycoses, Dysbiosis
Additional Keywords : Plant Extracts, Prebiotic
[+]

Resveratrol and tannic acid may exert a chemopreventive action by inhibiting nitric oxide in cancer cells. Oct 01, 2010

Pubmed Data : Cancer Biother Radiopharm. 2010 Oct;25(5):577-80. Epub 2010 Sep 28. PMID: 20874429
Article Published Date : Oct 01, 2010
Study Type : In Vitro Study
Additional Links
Substances : Resveratrol, Tannic Acid
Diseases : Breast Cancer, Colon Cancer
Pharmacological Actions : Anticarcinogenic Agents, Nitric Oxide Inhibitor
Additional Keywords : Stilbenes
[+]

Small molecules blocking the entry of severe acute respiratory syndrome coronavirus into host cells.Sep 30, 2004

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : J Virol. 2004 Oct ;78(20):11334-9. PMID: 15452254
Article Published Date : Sep 30, 2004
Study Type : In Vitro Study
Additional Links
Substances : Flavonoids, Luteolin, Tannic Acid
Diseases : Coronavirus Infection, HIV Infections, Severe Acute Respiratory Syndrome
Pharmacological Actions : Antiviral Agents
[+]

Tannic acid could be an adjuvant in the antibiotic therapy against multidrug resistant bacteria.Aug 11, 2017

Pubmed Data : Bioorg Chem. 2017 Aug 12 ;74:197-200. Epub 2017 Aug 12. PMID: 28841421
Article Published Date : Aug 11, 2017
Study Type : In Vitro Study
Additional Links
Substances : Tannic Acid
Diseases : Infection: Antibiotic Resistant, Staphylococcus aureus infection
Additional Keywords : Natural Substance/Drug Synergy
[+]

Tannic acid could serve as a potentially effective candidate for development of novel strategies to treat methicillin-resistant S. aureus infections.Aug 21, 2017

Pubmed Data : Nat Prod Res. 2017 Aug 22:1-4. Epub 2017 Aug 22. PMID: 28826250
Article Published Date : Aug 21, 2017
Study Type : In Vitro Study
Additional Links
Substances : Tannic Acid
Diseases : Staphylococcus aureus: Methicillin-resistant (MRSA), Staphylococcus aureus infection
Pharmacological Actions : Antimicrobial
[+]

Tannic acid inhibited norovirus by blocking its binding to HBGA receptors.Feb 14, 2012

Pubmed Data : Bioorg Med Chem. 2012 Feb 15 ;20(4):1616-23. Epub 2011 Nov 30. PMID: 22285570
Article Published Date : Feb 14, 2012
Study Type : In Vitro Study
Additional Links
Substances : Tannic Acid
Diseases : Norovirus
Pharmacological Actions : Antiviral Agents
Additional Keywords : Chinese Herbs
[+]

Tannic acid inhibits proliferation, migration, invasion of prostate cancer and modulates drug metabolizing and antioxidant enzymes.Nov 09, 2015

Pubmed Data : Anticancer Agents Med Chem. 2015 Nov 10. Epub 2015 Nov 10. PMID: 26555610
Article Published Date : Nov 09, 2015
Study Type : In Vitro Study
Additional Links
Substances : Tannic Acid
Diseases : Prostate Cancer
Pharmacological Actions : Anti-metastatic, Antiproliferative , Apoptotic, MicroRNA modulator
Additional Keywords : Dose Response
[+]

Tannic acid inhibits the gastric proton pump, indicating its anti-secretory and anti-ulcerogenic properties. Apr 01, 1992

Pubmed Data : J Nat Prod. 1992 Apr;55(4):513-6. PMID: 1324983
Article Published Date : Apr 01, 1992
Study Type : In Vitro Study
Additional Links
Substances : Tannic Acid
Diseases : Acid Reflux, Gastric Ulcer
Pharmacological Actions : Anti-Ulcer Agents, Proton Pump Inhibitor
[+]

Tannin inhibits HIV-1 entry into target cells. Feb 01, 2004

Pubmed Data : Acta Pharmacol Sin. 2004 Feb;25(2):213-8. PMID: 14769212
Article Published Date : Feb 01, 2004
Study Type : In Vitro Study
Additional Links
Substances : Tannic Acid
Diseases : HIV Infections
Pharmacological Actions : Antiviral Agents
[+]

These results indicate that methoxylated stilbenes are efficient inhibitors of glioma cell proliferation and apoptosis inducers.Aug 31, 2017

Pubmed Data : Toxicol In Vitro. 2017 Sep ;43:69-75. Epub 2017 Jun 6. PMID: 28595835
Article Published Date : Aug 31, 2017
Study Type : In Vitro Study
Additional Links
Substances : Pterostilbene, Resveratrol, Tannic Acid
Diseases : Glioma
Pharmacological Actions : Antiproliferative , Apoptotic, Cell cycle arrest, Tumor Suppressor Protein p53 Upregulation
[+]

These results indicate that Q. infectoria galls possess potent antioxidant activity, when tested both in chemical as well as biological models.Feb 14, 2008

Pubmed Data : Chem Biol Interact. 2008 Feb 15 ;171(3):272-82. Epub 2007 Oct 22. PMID: 18076871
Article Published Date : Feb 14, 2008
Study Type : In Vitro Study
Additional Links
Substances : Flavonoids, Polyphenols, Tannic Acid
Diseases : Oxidative Stress
Pharmacological Actions : Antioxidants
Additional Keywords : Plant Extracts
[+]

Tuberaria lignosa contains ellagitannins which inhibit HIV entry. Jan 01, 2010

Pubmed Data : Phytomedicine. 2010 Jan;17(1):69-74. Epub 2009 Sep 11. PMID: 19748255
Article Published Date : Jan 01, 2010
Study Type : In Vitro Study
Additional Links
Substances : Tannic Acid, Tuberaria
Diseases : HIV Infections
Pharmacological Actions : Antiviral Agents
[+]

Tannic acid exhibits antibacterial action against Staphylococcus aureus and exponentially amplifies the effect of conventional chemotherapy.Oct 01, 2001

Pubmed Data : J Antimicrob Chemother. 2001 Oct;48(4):487-91. PMID: 11581226
Article Published Date : Oct 01, 2001
Additional Links
Substances : Tannic Acid
[+]

Tannic acid induces programmed cell death and enhances chemotherapy in human leukemia cells.Sep 12, 2008

Pubmed Data : Leuk Res. 2008 Sep 12. PMID: 18790533
Article Published Date : Sep 12, 2008
Additional Links
Substances : Tannic Acid

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