Urolithin A

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8 Diseases Researched for Urolithin A

Name	AC	CK
Dysbiosis	1	10
Cachexia	1	2
Chemotherapy-Induced Toxicity: Cisplatin	1	2
Colon Cancer	1	2
Inflammation	1	2
Endometrial Cancer	1	1
Liver Cancer	1	1
Prostate Cancer	1	1

13 Pharmacological Actions Researched for Urolithin A

Name	AC	CK
Gastrointestinal Agents	1	10
Anti-Inflammatory Agents	4	7
Cell cycle arrest	2	3
Antiproliferative	2	2
Chemopreventive	2	2
Chemoprotective Agents	1	2
Chemosensitizer	1	2
Antioxidants	1	1
Apoptotic	1	1
P21 Activation	1	1
Superoxide Dismutase Up-regulation	1	1
Tumor Suppressor Protein p53 Upregulation	1	1
Wnt/β-catenin signaling pathway modulation	1	1

Research Articles 7
Cumulative Knowledge Score 11
Overall Research Rating GOOD

View the Evidence:
27 Abstracts with Urolithin A Research

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View the Evidence: 27 Abstracts with Urolithin A Research

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In UA producers, the genera Butyrivibrio, Enterobacter, Escherichia, Lactobacillus, Prevotella, Serratia and Veillonella were increased and Collinsella decreased significantly at week 4 compared to baseline.Jul 19, 2015

Co-treatments with Uro-A decreased IC50 values for both 5-FU and 5'DFUR and additionally arrested the cell cycle at the G2/M phase.Apr 30, 2015

Emblic leafflower (Phyllanthus emblica L.) fruits ameliorate vascular smooth muscle cell dysfunction in hyperglycemia.Dec 31, 2017

Neuroprotective effects of pomegranate juice against Parkinson's disease.Dec 26, 2019

Pomegranate peel polyphenols reduce chronic low-grade inflammatory responses in rats fed a high-fat diet.Nov 12, 2019

Supplementation with a punicalagin-rich pomegranate extract may protect skeletal muscle against an acute inflammation.Nov 01, 2016

The protective effect of urolithin a on cisplatin-induced nephrotoxicity.Jun 30, 2019

Urolithin A attenuates memory impairment and neuroinflammation.Mar 13, 2019

Urolithin A downregulates androgen receptor activation and suppresses growth of prostate cancer.Sep 30, 2018

Urolithin A improves insulin sensitivity through augmentation of mitochondrial function and biogenesis.Mar 31, 2019

Urolithin A may be a useful therapeutic agent for the treatment of Intervertebral disc degeneration.Dec 31, 2017

Urolithin A may be adopted as a new therapeutic agent for the treatment of osteoarthritis.Sep 08, 2019

Urolithin A mitigates cisplatin-induced nephrotoxicity in rats.Aug 06, 2017

Urolithin A protected against ischemic neuronal injury by reinforcing autophagy rather than mitophagy.Apr 10, 2019

Urolithin A shows anti-atherosclerotic activity.May 31, 2018

Urolithin A significantly attenuated the histopathological hallmarks of cisplatin-induced acute kidney injury and reduced mortality by 63%.Sep 17, 2019

An overview of natural plant products in the treatment of hepatocellular carcinoma.Jun 02, 2018

These findings indicated that urolithin A exerted a antiproliferative effect in liver cancer cells.Dec 31, 2017

These results indicate a potential role of urolithin A as a chemopreventive agent for prostate cancer.May 11, 2015

These results suggest that dietary consumption of urolithin A could induce autophagy and inhibit human colorectal cancer cell metastasis.Jan 31, 2018

This explains from a molecular perspective the beneficial effects and traditional use of pomegranate in the prevention of metabolic-associated disorders.Mar 27, 2018

Urolithin A could inhibit cell proliferation and reduce oxidative stress status in liver cancer. Jul 31, 2015

Urolithin A gains in antiproliferative capacity by reducing the glycolytic potential via the p53/TIGAR axis in colon cancer cells.Mar 11, 2019

Urolithin A induces prostate cancer cell death in p53-dependent and in p53-independent manner.Jun 07, 2019

Urolithin A modulates ERα-dependent gene expression and thereby inhibiting endometrial cancer proliferation.Jun 24, 2016

Urolithin A showed a strong potential of anti-aging.Sep 13, 2018

Urolithins A and B attenuated LPS-induced inflammation in BV2 microglia.Jan 23, 2018

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Urolithin A

View the Evidence:
27 Abstracts with Urolithin A Research