Urolithin A

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8 Diseases Researched for Urolithin A

Name	AC	CK
Dysbiosis	1	10
Cachexia	1	2
Chemotherapy-Induced Toxicity: Cisplatin	1	2
Colon Cancer	1	2
Inflammation	1	2
Endometrial Cancer	1	1
Liver Cancer	1	1
Prostate Cancer	1	1

13 Pharmacological Actions Researched for Urolithin A

Name	AC	CK
Gastrointestinal Agents	1	10
Anti-Inflammatory Agents	4	7
Cell cycle arrest	2	3
Antiproliferative	2	2
Chemopreventive	2	2
Chemoprotective Agents	1	2
Chemosensitizer	1	2
Antioxidants	1	1
Apoptotic	1	1
P21 Activation	1	1
Superoxide Dismutase Up-regulation	1	1
Tumor Suppressor Protein p53 Upregulation	1	1
Wnt/β-catenin signaling pathway modulation	1	1

Research Articles 7
Cumulative Knowledge Score 11
Overall Research Rating GOOD

View the Evidence:
23 Abstracts with Urolithin A Research

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View the Evidence: 23 Abstracts with Urolithin A Research

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In UA producers, the genera Butyrivibrio, Enterobacter, Escherichia, Lactobacillus, Prevotella, Serratia and Veillonella were increased and Collinsella decreased significantly at week 4 compared to baseline.Jul 19, 2015

Co-treatments with Uro-A decreased IC50 values for both 5-FU and 5'DFUR and additionally arrested the cell cycle at the G2/M phase.Apr 30, 2015

Emblic leafflower (Phyllanthus emblica L.) fruits ameliorate vascular smooth muscle cell dysfunction in hyperglycemia.Dec 31, 2017

Supplementation with a punicalagin-rich pomegranate extract may protect skeletal muscle against an acute inflammation.Nov 01, 2016

The protective effect of urolithin a on cisplatin-induced nephrotoxicity.Jun 30, 2019

Urolithin A attenuates memory impairment and neuroinflammation.Mar 13, 2019

Urolithin A downregulates androgen receptor activation and suppresses growth of prostate cancer.Sep 30, 2018

Urolithin A improves insulin sensitivity through augmentation of mitochondrial function and biogenesis.Mar 31, 2019

Urolithin A may be a useful therapeutic agent for the treatment of Intervertebral disc degeneration.Dec 31, 2017

Urolithin A mitigates cisplatin-induced nephrotoxicity in rats.Aug 06, 2017

Urolithin A protected against ischemic neuronal injury by reinforcing autophagy rather than mitophagy.Apr 10, 2019

Urolithin A shows anti-atherosclerotic activity.May 31, 2018

An overview of natural plant products in the treatment of hepatocellular carcinoma.Jun 02, 2018

These findings indicated that urolithin A exerted a antiproliferative effect in liver cancer cells.Dec 31, 2017

These results indicate a potential role of urolithin A as a chemopreventive agent for prostate cancer.May 11, 2015

These results suggest that dietary consumption of urolithin A could induce autophagy and inhibit human colorectal cancer cell metastasis.Jan 31, 2018

This explains from a molecular perspective the beneficial effects and traditional use of pomegranate in the prevention of metabolic-associated disorders.Mar 27, 2018

Urolithin A could inhibit cell proliferation and reduce oxidative stress status in liver cancer. Jul 31, 2015

Urolithin A gains in antiproliferative capacity by reducing the glycolytic potential via the p53/TIGAR axis in colon cancer cells.Mar 11, 2019

Urolithin A induces prostate cancer cell death in p53-dependent and in p53-independent manner.Jun 07, 2019

Urolithin A modulates ERα-dependent gene expression and thereby inhibiting endometrial cancer proliferation.Jun 24, 2016

Urolithin A showed a strong potential of anti-aging.Sep 13, 2018

Urolithins A and B attenuated LPS-induced inflammation in BV2 microglia.Jan 23, 2018

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Urolithin A

View the Evidence:
23 Abstracts with Urolithin A Research