Wogonin

Views 689
Jump to
Abstracts Focused Research Topics
Your Token Count0

Sign in to Purchase/Download Documents

Sign in / Register

Focus Your Research

Click any topic below to filter + focus research
69 Diseases Researched for Wogonin
NameACCKFocus
Cancers: Drug Resistant713Locked
Breast Cancer611Locked
Colon Cancer27Locked
Liver Cancer57Locked
Ovarian Cancer67Locked
Cancers: All55Locked
Cancers: Multi-Drug Resistant15Locked
Colorectal Cancer35Locked
Gastric Cancer45Locked
Leukemia45Locked
Lung Cancer45Locked
Asthma24Locked
Osteoarthritis34Locked
Alzheimer's Disease23Locked
Breast Cancer: Triple Negative 33Locked
Chemotherapy-Induced Toxicity: Cisplatin23Locked
Leukemia: Chronic myelogenous leukemia (CML) 23Locked
Osteosarcoma33Locked
Alcohol Toxicity 12Locked
Allergic Rhinitis12Locked
Brain Injury: Traumatic12Locked
Cadmium Poisoning 12Locked
Cerebral Hemorrhage12Locked
Cerebral Ischemia12Locked
Chronic Lymphocytic Leukemia12Locked
Colorectal Cancer: Prevention 12Locked
Corticosteroid-Induced Toxicity12Locked
DNA damage12Locked
Degenerative Disk Disease12Locked
Head and Neck Cancer12Locked
Kidney Damage: Chemically-Induced12Locked
Liver Fibrosis12Locked
Lung Cancer: Metastatic12Locked
Lymphoma12Locked
Multiple Myeloma12Locked
Myocardial Infarction12Locked
Nonalcoholic fatty liver disease (NAFLD)12Locked
Osteoarthritis: Knee12Locked
Oxidative Stress12Locked
Rheumatoid Arthritis12Locked
Squamous cell carcinoma12Locked
Testicular Injury: Cadmium-Induced12Locked
Acute Myeloid Leukemia11Locked
Acute lymphoblastic leukemia (ALL)11Locked
Alcoholic Liver Disease11Locked
Anxiety11Locked
Brain Inflammation 11Locked
Cancer Stem Cells11Locked
Cardiomyopathy11Locked
Cervical Cancer11Locked
Diabetes Mellitus: Type 211Locked
Diabetic Complications11Locked
Diabetic Nephropathy11Locked
Epilepsy11Locked
Hepatitis B 11Locked
Herpes Simplex Virus Type 111Locked
Herpes Simplex Virus Type 211Locked
Hyperglycemia11Locked
Inflammation11Locked
Influenza A11Locked
Kidney Cancer11Locked
Kidney Fibrosis11Locked
Macular Degeneration11Locked
Myelodysplastic Syndrome11Locked
Non-Small-Cell Lung Carcinoma11Locked
Pancreatic Cancer11Locked
Promyelocytic leukemia 11Locked
Sarcoma: Epithelioid11Locked
Steroid-Induced Toxicity11Locked
64 Pharmacological Actions Researched for Wogonin
NameACCKFocus
Apoptotic2840Locked
Antiproliferative 2537Locked
Anti-Inflammatory Agents2032Locked
Chemosensitizer1017Locked
Antioxidants915Locked
Interleukin-1 beta downregulation914Locked
NF-kappaB Inhibitor913Locked
Neuroprotective Agents711Locked
Tumor Necrosis Factor (TNF) Alpha Inhibitor710Locked
Anti-metastatic78Locked
Cyclooxygenase 2 Inhibitors68Locked
Interleukin-6 Downregulation68Locked
Nrf2 activation47Locked
Cell cycle arrest66Locked
Chemotherapeutic56Locked
Tumor Suppressor Protein p53 Upregulation56Locked
Chemopreventive45Locked
Heme oxygenase-1 up-regulation35Locked
Hypoxia-inducible factor-1 (HIF-1) inhibitor15Locked
Matrix metalloproteinase-9 (MMP-9) inhibitor55Locked
PI3K/Akt/signaling suppression15Locked
Angiogenesis Inhibitors34Locked
Antiviral Agents44Locked
Chondroprotective34Locked
Hypoxia inducible factor-1 alpha (HIF-1α) inhibitor34Locked
Interleukin-4 downregulation24Locked
Renoprotective34Locked
Anti-Apoptotic23Locked
Anti-Fibrotic23Locked
Antineoplastic Agents23Locked
Cardioprotective23Locked
Chemoprotective Agents23Locked
Cytotoxic33Locked
Immunomodulatory23Locked
Matrix Metalloproteinase-13 (MMP-13) Inhibitor23Locked
Matrix metalloproteinase-3 (MMP-3) inhibitor23Locked
Transforming growth factor beta (TGF-β) inhibitor23Locked
Anti Inflammatory12Locked
Anti-Asthmatic Agents12Locked
Anticarcinogenic Agents12Locked
Autophagy Up-regulation22Locked
Bcl-2 protein down-regulation22Locked
Cyclin D1 Down-Regulation22Locked
Cyclooxygenase Inhibitors12Locked
DNA Repair Up-regulation12Locked
Estrogen Receptor Modulators12Locked
Hepatoprotective12Locked
Interleukin-5 downregulation12Locked
Wnt/β-catenin signaling pathway modulation22Locked
Anti-Anxiety Agents11Locked
Anticonvulsants11Locked
Autophagy Inhibitors11Locked
EpCAM surface marker down-regulation11Locked
Hypoglycemic Agents11Locked
Interleukin-10 downregulation11Locked
Interleukin-8 downregulation11Locked
Matrix metalloproteinase-2 (MMP-2) inhibitor11Locked
Nitric Oxide Inhibitor11Locked
P21 Activation11Locked
Postaglandin PGE2 downregulation 11Locked
STAT3 Inhibitor11Locked
Telomerase Inhibitor11Locked
VEGFR3 inhibition 11Locked
Vascular Endothelial Growth Factor Inhibitors11Locked

View the Evidence:
98 Abstracts with Wogonin Research

[+]

Wogonin could increase doxorubicin sensitivity in human breast cancer cells.Dec 31, 2014

Pubmed Data : Cell Mol Biol (Noisy-le-grand). 2015 ;61(7):123-7. Epub 2015 Nov 30. PMID: 26638893
Article Published Date : Dec 31, 2014
Study Type : Human In Vitro
Additional Links
Substances : Wogonin
Diseases : Breast Cancer
Pharmacological Actions : Chemosensitizer
Additional Keywords : Chemotherapeutic Synergy: Doxorubicin, Dose Response
[+]

Wogonin decreased the expression of glycolysis-related proteins, glucose uptake and lactate generation in a dose-dependent manner.Jan 31, 2014

Pubmed Data : Mol Carcinog. 2014 Feb ;53 Suppl 1:E107-18. Epub 2013 Jun 13. PMID: 23761018
Article Published Date : Jan 31, 2014
Study Type : Animal Study, Human In Vitro
Additional Links
Substances : Wogonin
Diseases : Cancers: Drug Resistant, Cancers: Multi-Drug Resistant, Colon Cancer
Pharmacological Actions : Antiproliferative , Apoptotic, Hypoxia-inducible factor-1 (HIF-1) inhibitor, PI3K/Akt/signaling suppression
Additional Keywords : Cancer Glycolysis, Resistance Reversal
[+]

Baicalein, wogonin, and Scutellaria baicalensis ethanol extract alleviate ovalbumin-induced allergic airway inflammation May 31, 2017

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Anat Cell Biol. 2017 Jun ;50(2):124-134. Epub 2017 Jun 27. PMID: 28713616
Article Published Date : May 31, 2017
Study Type : Animal Study
Additional Links
Substances : Baicalein, Chinese Skullcap , Wogonin
Diseases : Asthma
Pharmacological Actions : Immunomodulatory, Interleukin-1 beta downregulation, Interleukin-4 downregulation, Interleukin-5 downregulation
[+]

Cardio protective role of wogonin loaded nanoparticle against isoproterenol induced myocardial infarction.Nov 09, 2019

Pubmed Data : Colloids Surf B Biointerfaces. 2019 Nov 10:110635. Epub 2019 Nov 10. PMID: 31744760
Article Published Date : Nov 09, 2019
Study Type : Animal Study
Additional Links
Substances : Wogonin
Diseases : Myocardial Infarction
Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants, Cardioprotective, Heme oxygenase-1 up-regulation, Nrf2 activation
[+]

Flavonoids can be utilized and developed as natural treatments for ischemia-induced injuries of the central nervous system.Dec 31, 2020

Pubmed Data : Oxid Med Cell Longev. 2021 ;2021:8377362. Epub 2021 Jun 29. PMID: 34306315
Article Published Date : Dec 31, 2020
Study Type : Animal Study
Additional Links
Substances : Baicalein, Wogonin
Diseases : Glaucoma, Ischemia
Pharmacological Actions : Neuroprotective Agents
[+]

Nephroprotective effect of wogonin against cadmium-induced nephrotoxicity.May 27, 2019

Pubmed Data : Hum Exp Toxicol. 2019 May 28:960327119842635. Epub 2019 May 28. PMID: 31132876
Article Published Date : May 27, 2019
Study Type : Animal Study
Additional Links
Substances : Wogonin
Diseases : Cadmium Poisoning , Kidney Damage: Chemically-Induced
Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants, Interleukin-1 beta downregulation, Tumor Necrosis Factor (TNF) Alpha Inhibitor
Problem Substances : Cadmium
[+]

Protective role of wogonin against cadmium induced testicular toxicity.Sep 30, 2020

Pubmed Data : Life Sci. 2020 Oct 1 ;258:118192. Epub 2020 Aug 8. PMID: 32781062
Article Published Date : Sep 30, 2020
Study Type : Animal Study
Additional Links
Substances : Wogonin
Diseases : Testicular Injury: Cadmium-Induced
Pharmacological Actions : Anti-Apoptotic, Anti-Inflammatory Agents, Antioxidants, Heme oxygenase-1 up-regulation, NF-kappaB Inhibitor, Nrf2 activation
Problem Substances : Cadmium
[+]

Selective anti-tumor activity of wogonin targeting the Warburg effect through stablizing p53.Jul 17, 2018

Pubmed Data : Pharmacol Res. 2018 Jul 18 ;135:49-59. Epub 2018 Jul 18. PMID: 30031170
Article Published Date : Jul 17, 2018
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Wogonin
Diseases : Colon Cancer, Liver Cancer, Ovarian Cancer
Pharmacological Actions : Antiproliferative , Tumor Suppressor Protein p53 Upregulation
Additional Keywords : Warburg Effect
[+]

There is potential therapeutic value of wogonin in the treatment of asthma.Aug 31, 2015

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : J Clin Biochem Nutr. 2015 Sep ;57(2):105-12. Epub 2015 Jul 30. PMID: 26388667
Article Published Date : Aug 31, 2015
Study Type : Animal Study
Additional Links
Substances : Wogonin
Diseases : Asthma
Pharmacological Actions : Anti-Asthmatic Agents, Anti-Inflammatory Agents, Interleukin-4 downregulation
[+]

These results show that the chondroprotective effects of wogonin are produced by its regulation of the gene expression.Aug 31, 2015

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Biomol Ther (Seoul). 2015 Sep ;23(5):442-8. Epub 2015 Sep 1. PMID: 26336584
Article Published Date : Aug 31, 2015
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Wogonin
Diseases : Osteoarthritis
Pharmacological Actions : Chondroprotective, Matrix metalloproteinase-3 (MMP-3) inhibitor
Additional Keywords : Gene Expression Regulation
[+]

Topical application of wogonin provides a novel treatment of knee osteoarthritis.Dec 31, 2019

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Front Physiol. 2020 ;11:80. Epub 2020 Feb 18. PMID: 32132930
Article Published Date : Dec 31, 2019
Study Type : Animal Study
Additional Links
Substances : Wogonin
Diseases : Osteoarthritis: Knee
Pharmacological Actions : Matrix Metalloproteinase-13 (MMP-13) Inhibitor, NF-kappaB Inhibitor, Transforming growth factor beta (TGF-β) inhibitor
[+]

Wogonin alleviates kidney tubular epithelial injury in diabetic nephropathy.Dec 31, 2020

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Drug Des Devel Ther. 2021 ;15:3131-3150. Epub 2021 Jul 16. PMID: 34295152
Article Published Date : Dec 31, 2020
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Wogonin
Diseases : Diabetic Nephropathy
Pharmacological Actions : Renoprotective
[+]

Wogonin ameliorate complete Freund's adjuvant induced rheumatoid arthritis.Nov 11, 2019

Pubmed Data : Biofactors. 2019 Nov 12. Epub 2019 Nov 12. PMID: 31721330
Article Published Date : Nov 11, 2019
Study Type : Animal Study
Additional Links
Substances : Wogonin
Diseases : Rheumatoid Arthritis
Pharmacological Actions : Anti-Inflammatory Agents
[+]

Wogonin and 5-fluorouracil combination treatment caused a significant growth inhibition of human tumor xenografts in vivo.Jul 31, 2013

Pubmed Data : Biochem Cell Biol. 2013 Aug ;91(4):221-9. Epub 2013 Feb 14. PMID: 23859016
Article Published Date : Jul 31, 2013
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Wogonin
Diseases : Liver Cancer
Pharmacological Actions : Antiproliferative , Chemosensitizer, Cyclooxygenase 2 Inhibitors, Cyclooxygenase Inhibitors
Additional Keywords : Drug: 5-flourouracil, Natural Substance/Drug Synergy, Plant Extracts
[+]

Wogonin as a potential therapeutic candidate for the therapeutic strategy in colorectal cancer treatment.Dec 31, 2017

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Front Pharmacol. 2018 ;9:1356. Epub 2018 Nov 23. PMID: 30532707
Article Published Date : Dec 31, 2017
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Wogonin
Diseases : Colorectal Cancer
Pharmacological Actions : Antiproliferative , Apoptotic, Chemopreventive
[+]

Wogonin attenuates the deleterious effects of traumatic brain injury.Apr 04, 2019

Pubmed Data : Eur J Pharmacol. 2019 Apr 5 ;848:121-130. Epub 2019 Jan 25. PMID: 30689996
Article Published Date : Apr 04, 2019
Study Type : Animal Study
Additional Links
Substances : Wogonin
Diseases : Brain Injury: Traumatic
Pharmacological Actions : Neuroprotective Agents
[+]

Wogonin can attenuate liver fibrosis via regulating the activation and apoptosis of hepatic stellate cells.Jul 31, 2019

Pubmed Data : Int Immunopharmacol. 2019 Aug 1 ;75:105671. Epub 2019 Aug 1. PMID: 31377590
Article Published Date : Jul 31, 2019
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Wogonin
Diseases : Liver Fibrosis
Pharmacological Actions : Anti-Fibrotic, Apoptotic, Hepatoprotective
[+]

Wogonin can be a promising chemoprotective agent and might be useful to avert secondary leukemia and other drug related cancers.Aug 31, 2013

Pubmed Data : Food Chem Toxicol. 2013 Sep ;59:724-30. Epub 2013 Jul 17. PMID: 23872129
Article Published Date : Aug 31, 2013
Study Type : Animal Study
Additional Links
Substances : Wogonin
Diseases : DNA damage, Leukemia, Oxidative Stress
Pharmacological Actions : Anticarcinogenic Agents, Antioxidants, DNA Repair Up-regulation
Additional Keywords : Epigenetic Modification
Problem Substances : Etoposide
[+]

Wogonin can be developed into an efficient natural sensitizer for resistant human myelogenous leukemiaFeb 01, 2017

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Sci Rep. 2017 Feb 2 ;7:39950. Epub 2017 Feb 2. PMID: 28150717
Article Published Date : Feb 01, 2017
Study Type : Animal Study
Additional Links
Substances : Wogonin
Diseases : Cancers: Drug Resistant, Leukemia: Chronic myelogenous leukemia (CML)
Pharmacological Actions : Chemosensitizer
[+]

Wogonin combined with low-dose paclitaxel obtained the same efficacy as with high dose Paclitaxel reducing tumor burden by 61%.Sep 30, 2013

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Chin J Cancer Res. 2013 Oct ;25(5):505-13. PMID: 24255573
Article Published Date : Sep 30, 2013
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Wogonin
Diseases : Gastric Cancer
Pharmacological Actions : Antiproliferative , Apoptotic
Additional Keywords : Chemothapeutic Synergy: Paclitaxel, Natural Substance/Drug Synergy
[+]

Wogonin could suppress tumor growth and induce cell apoptosis by inhibiting the expression of NF-κB.Feb 20, 2017

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : BMC Cancer. 2017 Feb 21 ;17(1):147. Epub 2017 Feb 21. PMID: 28222771
Article Published Date : Feb 20, 2017
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Wogonin
Diseases : Lymphoma
Pharmacological Actions : Antiproliferative , Apoptotic, NF-kappaB Inhibitor
[+]

Wogonin effectively suppressed inflammation associated colon carcinogenesis and cancer development in mice.Dec 31, 2013

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Cell Death Dis. 2014 ;5:e1283. Epub 2014 Jun 5. PMID: 24901054
Article Published Date : Dec 31, 2013
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Wogonin
Diseases : Colorectal Cancer, Colorectal Cancer: Prevention
Pharmacological Actions : Anti Inflammatory, Antineoplastic Agents, Antiproliferative , Interleukin-1 beta downregulation, Interleukin-6 Downregulation, NF-kappaB Inhibitor, Nrf2 activation
[+]

Wogonin facilitates hematoma clearance and neurobehavioral recovery by targeting PPAR-γ.Sep 11, 2020

Pubmed Data : Transl Stroke Res. 2020 Sep 12. Epub 2020 Sep 12. PMID: 32918259
Article Published Date : Sep 11, 2020
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Wogonin
Diseases : Cerebral Hemorrhage
Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-1 beta downregulation, Neuroprotective Agents, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

Wogonin has anticancer activity in both ER-positive and -negative breast cancer cells. Feb 15, 2008

Pubmed Data : Int J Cancer. 2008 Feb 15;122(4):816-22. PMID: 17957784
Article Published Date : Feb 15, 2008
Study Type : Animal Study
Additional Links
Substances : Wogonin
Diseases : Breast Cancer
Pharmacological Actions : Antiproliferative , Apoptotic, Estrogen Receptor Modulators
[+]

Wogonin improves functional neuroprotection for acute cerebral ischemia.Oct 31, 2019

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Ann Transl Med. 2019 Nov ;7(22):639. PMID: 31930040
Article Published Date : Oct 31, 2019
Study Type : Animal Study
Additional Links
Substances : Wogonin
Diseases : Cerebral Ischemia
Pharmacological Actions : Neuroprotective Agents
[+]

Wogonin induced antiallergic effects in a murine model of allergic rhinitis.Dec 31, 2017

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Allergy Rhinol (Providence). 2018 Jan-Dec;9:2152656718764145. Epub 2018 Apr 9. PMID: 29977652
Article Published Date : Dec 31, 2017
Study Type : Animal Study
Additional Links
Substances : Wogonin
Diseases : Allergic Rhinitis
Pharmacological Actions : Anti-Inflammatory Agents
[+]

wogonin may be a promising multifunctional drug candidate for Alzheimer's disease.Dec 31, 2016

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Evid Based Complement Alternat Med. 2017 ;2017:3545169. Epub 2017 Jun 7. PMID: 28680449
Article Published Date : Dec 31, 2016
Study Type : Transgenic Animal Study
Additional Links
Substances : Wogonin
Diseases : Alzheimer's Disease
Pharmacological Actions : Neuroprotective Agents
[+]

Wogonin might be a potential therapeutic agent for NAFLD.May 05, 2017

Pubmed Data : Biomed Pharmacother. 2017 May 6 ;91:621-631. Epub 2017 May 6. PMID: 28486193
Article Published Date : May 05, 2017
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Wogonin
Diseases : Nonalcoholic fatty liver disease (NAFLD)
Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants, Interleukin-6 Downregulation, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

Wogonin mitigates intervertebral disc degeneration.Nov 30, 2018

Pubmed Data : Int Immunopharmacol. 2018 Dec ;65:539-549. Epub 2018 Nov 6. PMID: 30412851
Article Published Date : Nov 30, 2018
Study Type : Animal Study
Additional Links
Substances : Wogonin
Diseases : Degenerative Disk Disease
Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants, Interleukin-1 beta downregulation
[+]

Wogonin pre-treatment attenuates cisplatin-induced nephrotoxicity.May 15, 2019

Pubmed Data : Chem Biol Interact. 2019 May 16. Epub 2019 May 16. PMID: 31103702
Article Published Date : May 15, 2019
Study Type : Animal Study
Additional Links
Substances : Wogonin
Diseases : Chemotherapy-Induced Toxicity: Cisplatin
Pharmacological Actions : Chemoprotective Agents, Renoprotective
[+]

Wogonin prevents alcohol-induced gastric mucosal damage in rats. Aug 01, 2008

Pubmed Data : Appl Environ Microbiol. 2008 Aug;74(15):4650-5. Epub 2008 Jun 6. PMID: 15139485
Article Published Date : Aug 01, 2008
Study Type : Animal Study
Additional Links
Substances : Wogonin
Diseases : Alcohol Toxicity
Pharmacological Actions : Apoptotic, Cyclooxygenase 2 Inhibitors
[+]

Wogonin protects glomerular podocytes by targeting Bcl-2-mediated autophagy and apoptosis in diabetic kidney disease.Jul 11, 2021

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Acta Pharmacol Sin. 2021 Jul 12. Epub 2021 Jul 12. PMID: 34253875
Article Published Date : Jul 11, 2021
Study Type : Animal Study
Additional Links
Substances : Wogonin
Diseases : Diabetic Nephropathy
Pharmacological Actions : Anti-Apoptotic, Renoprotective
[+]

Wogonin represses multiple myeloma stimulated angiogenesis and tumor progression.Dec 29, 2015

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Oncotarget. 2015 Dec 30. Epub 2015 Dec 30. PMID: 26735336
Article Published Date : Dec 29, 2015
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Wogonin
Diseases : Multiple Myeloma
Pharmacological Actions : Angiogenesis Inhibitors, Antiproliferative , Hypoxia inducible factor-1 alpha (HIF-1α) inhibitor
Additional Keywords : Natural Substance/Drug Synergy
[+]

Wogonin significantly sensitized resistant HNC cells to cisplatin both in vitro and in vivo. Aug 19, 2016

Pubmed Data : Apoptosis. 2016 Aug 20. Epub 2016 Aug 20. PMID: 27544755
Article Published Date : Aug 19, 2016
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Wogonin
Diseases : Cancers: Drug Resistant, Head and Neck Cancer
Pharmacological Actions : Chemosensitizer
Additional Keywords : Selective Cytotoxicity
[+]

Wogonin suppresses tumor cells migration in inflammatory microenvironment by inactivating STAT3 signaling.Jun 28, 2014

Pubmed Data : Mol Carcinog. 2014 Jun 29. Epub 2014 Jun 29. PMID: 24976450
Article Published Date : Jun 28, 2014
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Wogonin
Diseases : Lung Cancer, Lung Cancer: Metastatic
Pharmacological Actions : Anti-Inflammatory Agents, Anti-metastatic
Additional Keywords : Tumor Microenvironment
[+]

Wogonin treatment prevented leukemia development when given early after transplantation.Jan 10, 2018

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Haematologica. 2018 Jan 11. Epub 2018 Jan 11. PMID: 29326123
Article Published Date : Jan 10, 2018
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Wogonin
Diseases : Chronic Lymphocytic Leukemia
Pharmacological Actions : Anti-Inflammatory Agents, Chemotherapeutic
[+]

Wogonin, a compound found within Chinese Skullcap, prevents immunosuppressive action but not anti-inflammatory effect induced by glucocorticoid.Jul 01, 2008

Pubmed Data : Dig Dis Sci. 2008 Jul;53(7):1774-84. Epub 2008 Mar 27. PMID: 17404053
Article Published Date : Jul 01, 2008
Study Type : Animal Study
Additional Links
Substances : Chinese Skullcap , Wogonin
Diseases : Corticosteroid-Induced Toxicity
Pharmacological Actions : Anti-Inflammatory Agents, Apoptotic
[+]

Wogonoside attenuates cutaneous squamous cell carcinoma.Dec 31, 2019

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Onco Targets Ther. 2020 ;13:10097-10109. Epub 2020 Oct 9. PMID: 33116592
Article Published Date : Dec 31, 2019
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Wogonin
Diseases : Squamous cell carcinoma
Pharmacological Actions : Apoptotic
[+]

This review is the succinct appraisal of the pertinent articles on the mechanisms of anti-tumor properties of wogonin.Dec 31, 2016

Pubmed Data : Chin J Nat Med. 2017 Jan ;15(1):15-40. PMID: 28259249
Article Published Date : Dec 31, 2016
Study Type : Review
Additional Links
Substances : Wogonin
Diseases : Cancers: All, Cancers: Drug Resistant
Pharmacological Actions : Anti-metastatic, Apoptotic, Tumor Suppressor Protein p53 Upregulation
Additional Keywords : Phytotherapy
[+]

Wogonin induces cellular senescence in breast cancer via suppressing TXNRD2 expression.Jul 14, 2020

Pubmed Data : Arch Toxicol. 2020 Jul 15. Epub 2020 Jul 15. PMID: 32671444
Article Published Date : Jul 14, 2020
Study Type : In Vitro Study
Additional Links
Substances : Wogonin
Diseases : Breast Cancer
Pharmacological Actions : Antiproliferative
[+]

A review of targeting oncogenic transcription factors by polyphenols.Jan 03, 2018

Pubmed Data : Pharmacol Res. 2018 Jan 4. Epub 2018 Jan 4. PMID: 29305909
Article Published Date : Jan 03, 2018
Study Type : Review
Additional Links
Substances : 4-Shogaol, 6-Shogaol, Apigenin, Berberine, Caffeic Acid, Capsaicin, Cardamonin, Chrysin, Curcumin, EGCG (Epigallocatechin gallate), Ellagic Acid, Fisetin, Gingerol , Luteolin, Mangiferin, Piperlongumine , Polyphenols, Pterostilbene, Quercetin, Resveratrol, Rutin, Sesamin, Ursolic Acid, Wogonin, Xanthohumol
Diseases : Cancers: All
Pharmacological Actions : Chemopreventive, Chemotherapeutic, Hypoxia inducible factor-1 alpha (HIF-1α) inhibitor, NF-kappaB Inhibitor, STAT3 Inhibitor, Wnt/β-catenin signaling pathway modulation
[+]

A review of the anti-cancer natural products isolated from Chinese medicinal herbs.Jul 21, 2011

Pubmed Data : Chin Med. 2011 Jul 22 ;6(1):27. Epub 2011 Jul 22. PMID: 21777476
Article Published Date : Jul 21, 2011
Study Type : Review
Additional Links
Substances : Artemisinin, Berberine, Beta-Elemene, Curcumin, Emodin, Flavonoids, Ginsenosides, Shikonin, Silibinin, Ursolic Acid, Wogonin
Diseases : Cancers: All
Pharmacological Actions : Chemopreventive, Chemotherapeutic
Additional Keywords : Traditional Chinese Medicine
[+]

A wogonin-rich-fraction of Scutellaria baicalensis root extract exerts chondroprotective effects.Mar 02, 2017

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Sci Rep. 2017 Mar 3 ;7:43789. Epub 2017 Mar 3. PMID: 28256567
Article Published Date : Mar 02, 2017
Study Type : In Vitro Study
Additional Links
Substances : Wogonin
Diseases : Osteoarthritis
Pharmacological Actions : Anti-Inflammatory Agents, Chondroprotective, Cyclooxygenase 2 Inhibitors, Interleukin-1 beta downregulation, Interleukin-6 Downregulation, Matrix Metalloproteinase-13 (MMP-13) Inhibitor, Matrix metalloproteinase-3 (MMP-3) inhibitor, Matrix metalloproteinase-9 (MMP-9) inhibitor
[+]

Anti-tumor and anti-metastatic actions of wogonin isolated from Scutellaria baicalensis roots through anti-lymphangiogenesis.Feb 14, 2013

Pubmed Data : Phytomedicine. 2013 Feb 15 ;20(3-4):328-36. Epub 2012 Dec 6. PMID: 23219337
Article Published Date : Feb 14, 2013
Study Type : In Vitro Study
Additional Links
Substances : Chinese Skullcap , Wogonin
Diseases : Osteosarcoma
Pharmacological Actions : Anti-metastatic, Cyclooxygenase 2 Inhibitors, VEGFR3 inhibition
Additional Keywords : Phytotherapy
[+]

Anticancer effect of nor-wogonin on human triple-negative breast cancer cells via downregulation. Mar 31, 2019

Pubmed Data : Pharmacol Rep. 2019 Apr ;71(2):289-298. Epub 2019 Jan 7. PMID: 30826569
Article Published Date : Mar 31, 2019
Study Type : In Vitro Study
Additional Links
Substances : Wogonin
Diseases : Breast Cancer: Triple Negative
Pharmacological Actions : Antiproliferative
[+]

Baicalein, wogonin, and oroxylin A can effectively relieve Aβ25-35-stimulated neuronal apoptosis and inflammation.Nov 01, 2020

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Molecules. 2020 Nov 2 ;25(21). Epub 2020 Nov 2. PMID: 33147823
Article Published Date : Nov 01, 2020
Study Type : In Vitro Study
Additional Links
Substances : Baicalein, Wogonin
Diseases : Alzheimer's Disease
Pharmacological Actions : Anti-Apoptotic, Anti-Inflammatory Agents, Cyclooxygenase 2 Inhibitors, Neuroprotective Agents, Nitric Oxide Inhibitor, Postaglandin PGE2 downregulation , Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

Chemopreventive and anticancer activity of flavonoids and its possibility for clinical use by combining with conventional chemotherapeutic agents.Dec 31, 2018

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Am J Cancer Res. 2019 ;9(8):1517-1535. Epub 2019 Aug 1. PMID: 31497340
Article Published Date : Dec 31, 2018
Study Type : Review
Additional Links
Substances : Apigenin, Cyanidin, Delphinidin, Flavonoids, Kaempferol, Luteolin, Quercetin, Vitexins, Wogonin
Diseases : Cancers: All
Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants, Antiproliferative , Apoptotic, Chemopreventive, Chemosensitizer, Chemotherapeutic
[+]

Inhibitory effect of wogonin on human colorectal cancer cell SW480.Mar 31, 2020

Pubmed Data : Zhongguo Zhong Yao Za Zhi. 2020 Apr ;45(8):1772-1778. PMID: 32489060
Article Published Date : Mar 31, 2020
Study Type : In Vitro Study
Additional Links
Substances : Wogonin
Diseases : Colorectal Cancer
Pharmacological Actions : Antiproliferative , Wnt/β-catenin signaling pathway modulation
[+]

Oridonin and wogonin may suppress ovarian cancer stem cells.Jan 01, 2012

Pubmed Data : Discov Med. 2012 Jan ;13(68):7-17. PMID: 22284780
Article Published Date : Jan 01, 2012
Study Type : In Vitro Study
Additional Links
Substances : Oridonin, Wogonin
Diseases : Cancer Stem Cells, Ovarian Cancer
Pharmacological Actions : Antiproliferative , EpCAM surface marker down-regulation
[+]

Phytochemical modulation of apoptosis and autophagy could be used to overcome chemoresistance in leukemic stem cells.Dec 31, 2016

Pubmed Data : Int Rev Neurobiol. 2017 ;135:249-278. Epub 2017 Apr 12. PMID: 28807161
Article Published Date : Dec 31, 2016
Study Type : Review
Additional Links
Substances : Chrysin, Curcumin, Resveratrol, Wogonin
Diseases : Acute lymphoblastic leukemia (ALL), Acute Myeloid Leukemia, Leukemia
Pharmacological Actions : Apoptotic, Autophagy Up-regulation
Additional Keywords : Cancer Stem Cells
[+]

Potential therapeutic and pharmacological effects of Wogonin.Nov 30, 2020

Pubmed Data : Mol Biol Rep. 2020 Dec ;47(12):9779-9789. Epub 2020 Nov 9. PMID: 33165817
Article Published Date : Nov 30, 2020
Study Type : Review
Additional Links
Substances : Wogonin
Diseases : Anxiety, Inflammation
Pharmacological Actions : Anti-Anxiety Agents, Anti-Inflammatory Agents, Anticonvulsants, Antiviral Agents, Neuroprotective Agents
[+]

Sustained cytotoxicity of wogonin on breast cancer cells by encapsulation in solid lipid nanoparticles.Mar 12, 2018

Pubmed Data : Nanomaterials (Basel). 2018 Mar 13 ;8(3). Epub 2018 Mar 13. PMID: 29533979
Article Published Date : Mar 12, 2018
Study Type : In Vitro Study
Additional Links
Substances : Wogonin
Diseases : Breast Cancer
Pharmacological Actions : Cytotoxic
[+]

The present data suggests a potential clinical impact of wogonin for ovarian cancer patients.Dec 31, 2016

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Biomed Res Int. 2017 ;2017:9381513. Epub 2017 Oct 18. PMID: 29181409
Article Published Date : Dec 31, 2016
Study Type : In Vitro Study
Additional Links
Substances : Wogonin
Diseases : Ovarian Cancer
Pharmacological Actions : Apoptotic, Bcl-2 protein down-regulation, Tumor Suppressor Protein p53 Upregulation, Vascular Endothelial Growth Factor Inhibitors
[+]

The present study demonstrated that wogonin treatment specifically exhibits cytotoxicity effect on lung cancer cells.Oct 08, 2019

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Balkan Med J. 2019 Oct 9. Epub 2019 Oct 9. PMID: 31594288
Article Published Date : Oct 08, 2019
Study Type : In Vitro Study
Additional Links
Substances : Wogonin
Diseases : Lung Cancer
Pharmacological Actions : Antiproliferative , Apoptotic
[+]

The therapeutic potential of wogonin observed in preclinical studies. Dec 31, 2020

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Evid Based Complement Alternat Med. 2021 ;2021:9935451. Epub 2021 Jun 15. PMID: 34221094
Article Published Date : Dec 31, 2020
Study Type : Review
Additional Links
Substances : Wogonin
Diseases : Alzheimer's Disease
Pharmacological Actions : Neuroprotective Agents
[+]

This review we have discussed recently discovered therapeutic potential of wogonin in the treatment of diabetic cardiomyopathy.Jul 07, 2019

Pubmed Data : Curr Pharm Des. 2019 Jul 8. Epub 2019 Jul 8. PMID: 31298148
Article Published Date : Jul 07, 2019
Study Type : Review
Additional Links
Substances : Wogonin
Diseases : Cardiomyopathy, Diabetic Complications
Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants, Cardioprotective
[+]

This study clearly demonstrates that the combination of artesunate and wogonin exhibits synergistic anti-hepatocellular carcinoma effect.Dec 31, 2020

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Front Pharmacol. 2021 ;12:657080. Epub 2021 May 5. PMID: 34025421
Article Published Date : Dec 31, 2020
Study Type : In Vitro Study
Additional Links
Substances : Artesunate, Wogonin
Diseases : Liver Cancer
Pharmacological Actions : Apoptotic
Additional Keywords : Natural Substance Synergy
[+]

Wogonin acts as an ovary cancer cell proliferation inhibiting agent through activation of apoptosis.Nov 09, 2019

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Med Sci Monit. 2019 Nov 10 ;25:8465-8471. Epub 2019 Nov 10. PMID: 31707402
Article Published Date : Nov 09, 2019
Study Type : In Vitro Study
Additional Links
Substances : Wogonin
Diseases : Ovarian Cancer
Pharmacological Actions : Antiproliferative , Apoptotic, Cell cycle arrest
[+]

Wogonin affects proliferation and the energy metabolism of SGC-7901 and A549 cells.Dec 31, 2018

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Exp Ther Med. 2019 Jan ;17(1):911-918. Epub 2018 Nov 28. PMID: 30651880
Article Published Date : Dec 31, 2018
Study Type : In Vitro Study
Additional Links
Substances : Wogonin
Diseases : Gastric Cancer, Lung Cancer
Pharmacological Actions : Angiogenesis Inhibitors, Antiproliferative
[+]

Wogonin alleviates hyperglycemia through increased glucose entry into cells via AKT/GLUT4 pathway.Jul 21, 2019

Pubmed Data : Curr Pharm Des. 2019 Jul 22. Epub 2019 Jul 22. PMID: 31333118
Article Published Date : Jul 21, 2019
Study Type : In Vitro Study
Additional Links
Substances : Wogonin
Diseases : Diabetes Mellitus: Type 2, Hyperglycemia
Pharmacological Actions : Hypoglycemic Agents
[+]

Wogonin alleviates liver injury in sepsis through Nrf2-mediated NF-κB signalling suppression.May 31, 2021

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : J Cell Mol Med. 2021 Jun ;25(12):5782-5798. Epub 2021 May 12. PMID: 33982381
Article Published Date : May 31, 2021
Study Type : In Vitro Study
Additional Links
Substances : Wogonin
Diseases : Liver Damage, Sepsis
Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants, Heme oxygenase-1 up-regulation, Hepatoprotective, Nrf2 activation
[+]

Wogonin ameliorates renal inflammation and fibrosis in diabetic nephropathy.Dec 31, 2019

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Drug Des Devel Ther. 2020 ;14:4135-4148. Epub 2020 Oct 8. PMID: 33116403
Article Published Date : Dec 31, 2019
Study Type : In Vitro Study
Additional Links
Substances : Wogonin
Diseases : Diabetic Nephropathy, Kidney Fibrosis
Pharmacological Actions : Anti-Fibrotic, Anti-Inflammatory Agents, NF-kappaB Inhibitor, Renoprotective, Transforming growth factor beta (TGF-β) inhibitor
[+]

Wogonin and chrysin may contribute to overcoming drug resistance in non-small cell lung cancer cells. May 01, 2007

Pubmed Data : Int J Cancer. 2007 May 1;120(9):2019-27. PMID: 17266043
Article Published Date : May 01, 2007
Study Type : In Vitro Study
Additional Links
Substances : Chrysin, Flavonoids, Wogonin
Diseases : Cancers: Drug Resistant, Lung Cancer, Non-Small-Cell Lung Carcinoma
Pharmacological Actions : Apoptotic, Cell cycle arrest, Interleukin-6 Downregulation
Additional Keywords : Drug: Doxorubicin
[+]

Wogonin attenuates inflammation by activating PPAR-γ in alcoholic liver disease.Aug 31, 2017

Pubmed Data : Int Immunopharmacol. 2017 Sep ;50:95-106. Epub 2017 Jun 21. PMID: 28646664
Article Published Date : Aug 31, 2017
Study Type : In Vitro Study
Additional Links
Substances : Wogonin
Diseases : Alcoholic Liver Disease
Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-6 Downregulation, NF-kappaB Inhibitor, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

Wogonin can be a potential therapeutic candidate for enhancing the efficacy of oxaliplatin in gastric cancer treatment.Jan 14, 2018

Pubmed Data : Phytomedicine. 2018 Jan 15 ;39:168-175. Epub 2017 Dec 18. PMID: 29433678
Article Published Date : Jan 14, 2018
Study Type : In Vitro Study
Additional Links
Substances : Wogonin
Diseases : Gastric Cancer
Pharmacological Actions : Chemosensitizer, Chemotherapeutic
Additional Keywords : Chemotherapeutic Synergy: Oxaliplatin
[+]

Wogonin could be a potential therapy for the treatment of age-related macular degeneration.Mar 31, 2017

Pubmed Data : Mol Med Rep. 2017 Apr ;15(4):2289-2295. Epub 2017 Feb 28. PMID: 28260013
Article Published Date : Mar 31, 2017
Study Type : In Vitro Study
Additional Links
Substances : Wogonin
Diseases : Macular Degeneration
Pharmacological Actions : Cyclooxygenase 2 Inhibitors, Interleukin-1 beta downregulation, Interleukin-6 Downregulation, Interleukin-8 downregulation
[+]

Wogonin could be an ideal candidate for increasing sorafenibs activity in hepatocellular carcinoma therapy.May 31, 2017

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Oncol Lett. 2017 Jun ;13(6):5028-5034. Epub 2017 Apr 20. PMID: 28599504
Article Published Date : May 31, 2017
Study Type : In Vitro Study
Additional Links
Substances : Wogonin
Diseases : Liver Cancer
Pharmacological Actions : Apoptotic, Autophagy Inhibitors
Additional Keywords : Chemothapeutic Synergy: Sorafenib
[+]

Wogonin could significantly increase the sensitivity of cisplatin-resistant ovarian cancer cells to cisplatin.Aug 11, 2019

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Med Sci Monit. 2019 Aug 12 ;25:6007-6014. Epub 2019 Aug 12. PMID: 31402794
Article Published Date : Aug 11, 2019
Study Type : In Vitro Study
Additional Links
Substances : Wogonin
Diseases : Ovarian Cancer
Pharmacological Actions : Apoptotic, Chemosensitizer
Additional Keywords : Chemotherapeutic Synergy: Cisplatin
[+]

Wogonin has a synergistic effect with 5-fluorouracil, etoposide, and adriamycin to enhance chemotherapy and reverse drug resistance.Dec 31, 2015

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Onco Targets Ther. 2016 ;9:2935-43. Epub 2016 May 17. PMID: 27274287
Article Published Date : Dec 31, 2015
Study Type : Review
Additional Links
Substances : Chinese Skullcap , Wogonin
Diseases : Cancers: All
Pharmacological Actions : Angiogenesis Inhibitors, Antiproliferative , Apoptotic, Chemosensitizer
Additional Keywords : Chemothapeutic Synergy: 5-flourouracil, Natural Substance/Drug Synergy
[+]

Wogonin has anti-hepatitis B virus effects. Nov 30, 2000

Pubmed Data : Planta Med. 2000 Dec ;66(8):694-8. PMID: 11199123
Article Published Date : Nov 30, 2000
Study Type : In Vitro Study
Additional Links
Substances : Wogonin
Diseases : Hepatitis B
Pharmacological Actions : Antiviral Agents
[+]

Wogonin has the ability to inhibit the proliferation of gastric cancer cells.May 31, 2016

Pubmed Data : Zhong Yao Cai. 2016 Jun ;39(6):1372-6. PMID: 30156810
Article Published Date : May 31, 2016
Study Type : In Vitro Study
Additional Links
Substances : Wogonin
Diseases : Gastric Cancer
Pharmacological Actions : Anti-metastatic, Antiproliferative , Apoptotic
[+]

Wogonin induces apoptosis and down-regulates survivin in human breast cancer MCF-7 cells.Jan 31, 2012

Pubmed Data : Int Immunopharmacol. 2012 Feb ;12(2):334-41. Epub 2011 Dec 17. PMID: 22182776
Article Published Date : Jan 31, 2012
Study Type : In Vitro Study
Additional Links
Substances : Wogonin
Diseases : Breast Cancer
Pharmacological Actions : Antineoplastic Agents, Antiproliferative , Apoptotic, Bcl-2 protein down-regulation, Cell cycle arrest, Tumor Suppressor Protein p53 Upregulation
[+]

Wogonin induces apoptosis and reverses sunitinib resistance of renal cell carcinoma cells.Dec 31, 2019

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Front Pharmacol. 2020 ;11:1152. Epub 2020 Jul 24. PMID: 32792963
Article Published Date : Dec 31, 2019
Study Type : In Vitro Study
Additional Links
Substances : Wogonin
Diseases : Cancers: Drug Resistant, Kidney Cancer
Pharmacological Actions : Apoptotic, Chemosensitizer
[+]

Wogonin induces apoptosis of human osteosarcoma cancer stem cells.Jun 11, 2017

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : BMC Complement Altern Med. 2017 Jun 12 ;17(1):304. Epub 2017 Jun 12. PMID: 28606135
Article Published Date : Jun 11, 2017
Study Type : In Vitro Study
Additional Links
Substances : Wogonin
Diseases : Osteosarcoma
Pharmacological Actions : Apoptotic, Matrix metalloproteinase-9 (MMP-9) inhibitor
Additional Keywords : Cancer Stem Cells
[+]

Wogonin induces Beclin-1/PI3K and reactive oxygen species-mediated autophagy in human pancreatic cancer cells.Nov 30, 2016

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Oncol Lett. 2016 Dec ;12(6):5059-5067. Epub 2016 Nov 8. PMID: 28105213
Article Published Date : Nov 30, 2016
Study Type : In Vitro Study
Additional Links
Substances : Wogonin
Diseases : Pancreatic Cancer
Pharmacological Actions : Autophagy Up-regulation
[+]

Wogonin induces cell cycle arrest and apoptosis of hepatocellular carcinoma cells.Aug 22, 2021

Pubmed Data : Anticancer Agents Med Chem. 2021 Aug 23. Epub 2021 Aug 23. PMID: 34431466
Article Published Date : Aug 22, 2021
Study Type : In Vitro Study
Additional Links
Substances : Wogonin
Diseases : Liver Cancer
Pharmacological Actions : Antiproliferative , Apoptotic, Cell cycle arrest
[+]

Wogonin induces differentiation and cell cycle arrest in human leukemia cells. Sep 04, 2008

Pubmed Data : Eur J Pharmacol. 2008 Sep 4;591(1-3):7-12. Epub 2008 Jun 12. PMID: 18577379
Article Published Date : Sep 04, 2008
Study Type : In Vitro Study
Additional Links
Substances : Wogonin
Diseases : Leukemia
Pharmacological Actions : Cell cycle arrest
[+]

Wogonin induces programmed cell death in human ovarian cancer cells. Aug 01, 2003

Pubmed Data : Ai Zheng. 2003 Aug;22(8):801-5. PMID: 12917023
Article Published Date : Aug 01, 2003
Study Type : In Vitro Study
Additional Links
Substances : Wogonin
Diseases : Ovarian Cancer
Pharmacological Actions : Antiproliferative , Apoptotic
[+]

Wogonin inhibits cardiac hypertrophy by activating Nrf-2-mediated antioxidant responses.Dec 31, 2020

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Cardiovasc Ther. 2021 ;2021:9995342. Epub 2021 Jul 1. PMID: 34290825
Article Published Date : Dec 31, 2020
Study Type : In Vitro Study
Additional Links
Substances : Wogonin
Diseases : Cardiac Hypertrophy
Pharmacological Actions : Antioxidants, Cardioprotective, Nrf2 activation
[+]

Wogonin inhibits cell cycle progression by activating the glycogen synthase kinase-3 beta in hepatocellular carcinoma.Jan 17, 2020

Pubmed Data : Phytomedicine. 2020 Jan 18 ;68:153174. Epub 2020 Jan 18. PMID: 31991293
Article Published Date : Jan 17, 2020
Study Type : In Vitro Study
Additional Links
Substances : Wogonin
Diseases : Liver Cancer
Pharmacological Actions : Antiproliferative , Cell cycle arrest, Cyclin D1 Down-Regulation
[+]

Wogonin inhibits in vitro herpes simplex virus type 1 and 2 infection.Jul 27, 2020

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : BMC Microbiol. 2020 Jul 28 ;20(1):227. Epub 2020 Jul 28. PMID: 32723300
Article Published Date : Jul 27, 2020
Study Type : In Vitro Study
Additional Links
Substances : Wogonin
Diseases : Herpes Simplex Virus Type 1, Herpes Simplex Virus Type 2
Pharmacological Actions : Antiviral Agents
[+]

Wogonin inhibits the proliferation of myelodysplastic syndrome cells.Oct 31, 2015

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Mol Med Rep. 2015 Nov ;12(5):7285-92. Epub 2015 Sep 23. PMID: 26398525
Article Published Date : Oct 31, 2015
Study Type : In Vitro Study
Additional Links
Substances : Wogonin
Diseases : Myelodysplastic Syndrome
Pharmacological Actions : Antiproliferative , Apoptotic, Cell cycle arrest, Cyclin D1 Down-Regulation, P21 Activation
[+]

Wogonin intercalates with genomic DNA and exhibits protective effects in IL-1β stimulated osteoarthritis chondrocytes.Aug 24, 2017

Pubmed Data : Chem Biol Interact. 2017 Aug 25 ;274:13-23. Epub 2017 Jul 5. PMID: 28688942
Article Published Date : Aug 24, 2017
Study Type : In Vitro Study
Additional Links
Substances : Wogonin
Diseases : Osteoarthritis
Pharmacological Actions : Chondroprotective, Interleukin-1 beta downregulation
[+]

Wogonin may be a promising candidate for successful clinical management of osteosarcoma.Apr 30, 2020

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : In Vivo. 2020 May-Jun;34(3):1077-1084. PMID: 32354895
Article Published Date : Apr 30, 2020
Study Type : In Vitro Study
Additional Links
Substances : Wogonin
Diseases : Osteosarcoma
Pharmacological Actions : Cytotoxic
Additional Keywords : Cancer Stem Cells
[+]

Wogonin might be a potent treatment option for disrupting the tumor metastasis that favours liver cancer development.Feb 10, 2018

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Molecules. 2018 Feb 11 ;23(2). Epub 2018 Feb 11. PMID: 29439451
Article Published Date : Feb 10, 2018
Study Type : In Vitro Study
Additional Links
Substances : Wogonin
Diseases : Liver Cancer
Pharmacological Actions : Anti-metastatic, Matrix metalloproteinase-9 (MMP-9) inhibitor
[+]

Wogonin possesses a potent anti-influenza activity.Dec 31, 2017

Pubmed Data : Acta Virol. 2018 ;62(1):78-85. PMID: 29521106
Article Published Date : Dec 31, 2017
Study Type : In Vitro Study
Additional Links
Substances : Wogonin
Diseases : Influenza A
Pharmacological Actions : Antiviral Agents
[+]

Wogonin preventive impact on hippocampal neurodegeneration, inflammation and cognitive defects in temporal lobe epilepsy.Jul 31, 2020

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Saudi J Biol Sci. 2020 Aug ;27(8):2149-2156. Epub 2020 May 22. PMID: 32742183
Article Published Date : Jul 31, 2020
Study Type : In Vitro Study
Additional Links
Substances : Wogonin
Diseases : Brain Inflammation , Epilepsy
Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants, Heme oxygenase-1 up-regulation, Interleukin-1 beta downregulation, Neuroprotective Agents, NF-kappaB Inhibitor, Nrf2 activation, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

Wogonin protects against cisplatin-induced acute kidney injury.Dec 31, 2017

Pubmed Data : Lab Invest. 2018 Jan ;98(1):79-94. Epub 2017 Dec 4. PMID: 29200200
Article Published Date : Dec 31, 2017
Study Type : In Vitro Study
Additional Links
Substances : Wogonin
Diseases : Chemotherapy-Induced Toxicity: Cisplatin
Pharmacological Actions : Chemoprotective Agents, Renoprotective
[+]

Wogonin reverses the drug resistance of chronic myelogenous leukemia cells to imatinib.Aug 31, 2020

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Ann Transl Med. 2020 Sep ;8(17):1046. PMID: 33145265
Article Published Date : Aug 31, 2020
Study Type : In Vitro Study
Additional Links
Substances : Wogonin
Diseases : Cancers: Drug Resistant, Leukemia: Chronic myelogenous leukemia (CML)
Pharmacological Actions : Chemosensitizer
Additional Keywords : Chemothapeutic Synergy: Imatinib
[+]

Wogonin sensitizes TNF alpha-resistant leukemia cells to TNF alpha-induced programmed cell death. Dec 01, 2006

Pubmed Data : Blood. 2006 Dec 1;108(12):3700-6. Epub 2006 Aug 24. PMID: 16931628
Article Published Date : Dec 01, 2006
Study Type : In Vitro Study
Additional Links
Substances : Wogonin
Diseases : Leukemia
Pharmacological Actions : Apoptotic, NF-kappaB Inhibitor, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

Wogonin strengthens the therapeutic effects of mesenchymal stem cells in DSS-induced colitis.Dec 31, 2020

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Oxid Med Cell Longev. 2021 ;2021:5527935. Epub 2021 Jun 17. PMID: 34239686
Article Published Date : Dec 31, 2020
Study Type : In Vitro Study
Additional Links
Substances : Wogonin
Diseases : Colitis
Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-10 upregulation
Additional Keywords : Mesenchymal Stem Cells
[+]

Wogonin suppresses IL-10 production in B cells via STAT3 and ERK signaling pathway.Dec 31, 2019

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : J Immunol Res. 2020 ;2020:3032425. Epub 2020 Jun 1. PMID: 32566686
Article Published Date : Dec 31, 2019
Study Type : In Vitro Study
Additional Links
Substances : Wogonin
Pharmacological Actions : Hypoxia inducible factor-1 alpha (HIF-1α) inhibitor, Immunomodulatory, Interleukin-10 downregulation
[+]

Wogonin suppresses proliferation and invasion of skin epithelioid carcinoma cells through Notch1.Sep 29, 2020

Pubmed Data : Cell Mol Biol (Noisy-le-grand). 2020 Sep 30 ;66(6):29-33. Epub 2020 Sep 30. PMID: 33040781
Article Published Date : Sep 29, 2020
Study Type : In Vitro Study
Additional Links
Substances : Wogonin
Diseases : Sarcoma: Epithelioid
Pharmacological Actions : Antiproliferative
[+]

Wogonin suppresses the LPS‑enhanced invasiveness of MDA‑MB‑231 breast cancer cells.Sep 30, 2018

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Int J Mol Med. 2018 Oct ;42(4):1899-1908. Epub 2018 Jul 12. PMID: 30015917
Article Published Date : Sep 30, 2018
Study Type : In Vitro Study
Additional Links
Substances : Wogonin
Diseases : Breast Cancer: Triple Negative
Pharmacological Actions : Anti-metastatic, Matrix metalloproteinase-9 (MMP-9) inhibitor
[+]

Wogonin was cytotoxic to HPV 16 cervical cancer cells SiHa and CaSki but not to HPV negative cells.Jul 31, 2013

Pubmed Data : Cell Biol Toxicol. 2013 Aug ;29(4):259-72. Epub 2013 Aug 18. PMID: 23955116
Article Published Date : Jul 31, 2013
Study Type : In Vitro Study
Additional Links
Substances : Flavonoids, Wogonin
Diseases : Cervical Cancer
Pharmacological Actions : Apoptotic, Cytotoxic, Tumor Suppressor Protein p53 Upregulation
Additional Keywords : Oncogene Proteins, Plant Extracts, Selective Cytotoxicity
[+]

Wogonin, a compound within Chinese Skullcap, attenuates the adverse side effects of glucocorticoid-induced changes, without reducing the drug's anti-inflammatory effects.Aug 01, 2007

Pubmed Data : J Pharmacol Sci. 2007 Aug;104(4):355-65. Epub 2007 Aug 10. PMID:17690528
Article Published Date : Aug 01, 2007
Study Type : In Vitro Study
Additional Links
Substances : Chinese Skullcap , Wogonin
Diseases : Steroid-Induced Toxicity
Additional Keywords : Drug Side Effect Attenuation
[+]

Wogonin, an active compound in Scutellaria baicalensis, induces apoptosis and reduces telomerase activity in the promyelocytic leukemia cells.Jan 01, 2010

Pubmed Data : Phytomedicine. 2010 Jan;17(1):47-54. Epub 2009 Jul 3. PMID: 19577445
Article Published Date : Jan 01, 2010
Study Type : In Vitro Study
Additional Links
Substances : Chinese Skullcap , Wogonin
Diseases : Promyelocytic leukemia
Pharmacological Actions : Apoptotic, Telomerase Inhibitor
[+]

Wogonoside might be a potential therapeutic agent for the treatment of tumor metastasis in breast cancer.Aug 02, 2017

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : J Exp Clin Cancer Res. 2017 Aug 3 ;36(1):103. Epub 2017 Aug 3. PMID: 28774312
Article Published Date : Aug 02, 2017
Study Type : In Vitro Study
Additional Links
Substances : Wogonin
Diseases : Breast Cancer, Breast Cancer: Triple Negative
Pharmacological Actions : Anti-metastatic, Antiproliferative , Matrix metalloproteinase-2 (MMP-2) inhibitor, Matrix metalloproteinase-9 (MMP-9) inhibitor

Copyright: radiantskies / 123RF Stock Photo

Print Options

Some features are currently member only features. If you are already a member, please login. Otherwise, click here to become a member.

Connect with GreenMedInfo

MeWe

This website is for information purposes only. By providing the information contained herein we are not diagnosing, treating, curing, mitigating, or preventing any type of disease or medical condition. Before beginning any type of natural, integrative or conventional treatment regimen, it is advisable to seek the advice of a licensed healthcare professional.

© Copyright 2008-2021 GreenMedInfo.com, Journal Articles copyright of original owners, MeSH copyright NLM.