Wogonin

Views 599
Jump to
Abstracts Focused Research Topics
Your Token Count0

Sign in to Purchase/Download Documents

Sign in / Register

Focus Your Research

Click any topic below to filter + focus research
40 Diseases Researched for Wogonin
NameACCKFocus
Cancers: Drug Resistant511Locked
Breast Cancer49Locked
Cancers: Multi-Drug Resistant15Locked
Colon Cancer15Locked
Leukemia45Locked
Asthma24Locked
Liver Cancer34Locked
Osteoarthritis34Locked
Cancers: All33Locked
Gastric Cancer23Locked
Lung Cancer23Locked
Ovarian Cancer33Locked
Alcohol Toxicity 12Locked
Alzheimer's Disease12Locked
Chronic Lymphocytic Leukemia12Locked
Colorectal Cancer12Locked
Colorectal Cancer: Prevention 12Locked
Corticosteroid-Induced Toxicity12Locked
DNA damage12Locked
Head and Neck Cancer12Locked
Leukemia: Chronic myelogenous leukemia (CML) 12Locked
Lung Cancer: Metastatic12Locked
Lymphoma12Locked
Multiple Myeloma12Locked
Nonalcoholic fatty liver disease (NAFLD) 12Locked
Osteosarcoma22Locked
Oxidative Stress12Locked
Acute Myeloid Leukemia11Locked
Acute lymphoblastic leukemia (ALL)11Locked
Alcoholic Liver Disease11Locked
Breast Cancer: Triple Negative 11Locked
Cancer Stem Cells11Locked
Cervical Cancer11Locked
Chemotherapy-Induced Toxicity: Cisplatin11Locked
Macular Degeneration11Locked
Myelodysplastic Syndrome11Locked
Non-Small-Cell Lung Carcinoma11Locked
Pancreatic Cancer11Locked
Promyelocytic leukemia 11Locked
Steroid-Induced Toxicity11Locked
51 Pharmacological Actions Researched for Wogonin
NameACCKFocus
Apoptotic1928Locked
Antiproliferative 1323Locked
Chemosensitizer613Locked
Anti-Inflammatory Agents712Locked
Interleukin-6 Downregulation68Locked
Cyclooxygenase 2 Inhibitors57Locked
Interleukin-1 beta downregulation57Locked
NF-kappaB Inhibitor57Locked
Anti-metastatic56Locked
Hypoxia-inducible factor-1 (HIF-1) inhibitor15Locked
PI3K/Akt/signaling suppression15Locked
Antioxidants24Locked
Cell cycle arrest44Locked
Chemotherapeutic34Locked
Chondroprotective34Locked
Interleukin-4 downregulation24Locked
Matrix metalloproteinase-9 (MMP-9) inhibitor44Locked
Tumor Necrosis Factor (TNF) Alpha Inhibitor34Locked
Tumor Suppressor Protein p53 Upregulation44Locked
Angiogenesis Inhibitors23Locked
Antineoplastic Agents23Locked
Hypoxia inducible factor-1 alpha (HIF-1α) inhibitor23Locked
Matrix metalloproteinase-3 (MMP-3) inhibitor23Locked
Anti Inflammatory12Locked
Anti-Asthmatic Agents12Locked
Anticarcinogenic Agents12Locked
Autophagy Up-regulation22Locked
Bcl-2 protein down-regulation22Locked
Cyclooxygenase Inhibitors12Locked
DNA Repair Up-regulation12Locked
Estrogen Receptor Modulators12Locked
Immunomodulatory12Locked
Interleukin-5 downregulation12Locked
Neuroprotective Agents12Locked
Nrf2 activation12Locked
Autophagy Inhibitors11Locked
Chemopreventive11Locked
Chemoprotective Agents11Locked
Cyclin D1 Down-Regulation11Locked
Cytotoxic11Locked
EpCAM surface marker down-regulation11Locked
Interleukin-8 downregulation11Locked
Matrix Metalloproteinase-13 (MMP-13) Inhibitor11Locked
Matrix metalloproteinase-2 (MMP-2) inhibitor11Locked
P21 Activation11Locked
Renoprotective11Locked
STAT3 Inhibitor11Locked
Telomerase Inhibitor11Locked
VEGFR3 inhibition 11Locked
Vascular Endothelial Growth Factor Inhibitors11Locked
Wnt/β-catenin signaling pathway modulation11Locked

View the Evidence:
73 Abstracts with Wogonin Research

[+]

Wogonin could increase doxorubicin sensitivity in human breast cancer cells.Dec 31, 2014

Pubmed Data : Cell Mol Biol (Noisy-le-grand). 2015 ;61(7):123-7. Epub 2015 Nov 30. PMID: 26638893
Article Published Date : Dec 31, 2014
Study Type : Human In Vitro
Additional Links
Substances : Wogonin
Diseases : Breast Cancer
Pharmacological Actions : Chemosensitizer
Additional Keywords : Chemotherapeutic Synergy: Doxorubicin, Dose Response
[+]

Wogonin decreased the expression of glycolysis-related proteins, glucose uptake and lactate generation in a dose-dependent manner.Jan 31, 2014

Pubmed Data : Mol Carcinog. 2014 Feb ;53 Suppl 1:E107-18. Epub 2013 Jun 13. PMID: 23761018
Article Published Date : Jan 31, 2014
Study Type : Animal Study, Human In Vitro
Additional Links
Substances : Wogonin
Diseases : Cancers: Drug Resistant, Cancers: Multi-Drug Resistant, Colon Cancer
Pharmacological Actions : Antiproliferative , Apoptotic, Hypoxia-inducible factor-1 (HIF-1) inhibitor, PI3K/Akt/signaling suppression
Additional Keywords : Cancer Glycolysis, Resistance Reversal
[+]

Baicalein, wogonin, and Scutellaria baicalensis ethanol extract alleviate ovalbumin-induced allergic airway inflammation May 31, 2017

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Anat Cell Biol. 2017 Jun ;50(2):124-134. Epub 2017 Jun 27. PMID: 28713616
Article Published Date : May 31, 2017
Study Type : Animal Study
Additional Links
Substances : Baicalein, Chinese Skullcap , Wogonin
Diseases : Asthma
Pharmacological Actions : Immunomodulatory, Interleukin-1 beta downregulation, Interleukin-4 downregulation, Interleukin-5 downregulation
[+]

Cardio protective role of wogonin loaded nanoparticle against isoproterenol induced myocardial infarction.Nov 09, 2019

Pubmed Data : Colloids Surf B Biointerfaces. 2019 Nov 10:110635. Epub 2019 Nov 10. PMID: 31744760
Article Published Date : Nov 09, 2019
Study Type : Animal Study
Additional Links
Substances : Wogonin
Diseases : Myocardial Infarction
Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants, Cardioprotective, Heme oxygenase-1 up-regulation, Nrf2 activation
[+]

Nephroprotective effect of wogonin against cadmium-induced nephrotoxicity.May 27, 2019

Pubmed Data : Hum Exp Toxicol. 2019 May 28:960327119842635. Epub 2019 May 28. PMID: 31132876
Article Published Date : May 27, 2019
Study Type : Animal Study
Additional Links
Substances : Wogonin
Diseases : Cadmium Poisoning , Kidney Damage: Chemically-Induced
Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants, Interleukin-1 beta downregulation, Tumor Necrosis Factor (TNF) Alpha Inhibitor
Problem Substances : Cadmium
[+]

Selective anti-tumor activity of wogonin targeting the Warburg effect through stablizing p53.Jul 17, 2018

Pubmed Data : Pharmacol Res. 2018 Jul 18 ;135:49-59. Epub 2018 Jul 18. PMID: 30031170
Article Published Date : Jul 17, 2018
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Wogonin
Diseases : Colon Cancer, Liver Cancer, Ovarian Cancer
Pharmacological Actions : Antiproliferative , Tumor Suppressor Protein p53 Upregulation
Additional Keywords : Warburg Effect
[+]

There is potential therapeutic value of wogonin in the treatment of asthma.Aug 31, 2015

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : J Clin Biochem Nutr. 2015 Sep ;57(2):105-12. Epub 2015 Jul 30. PMID: 26388667
Article Published Date : Aug 31, 2015
Study Type : Animal Study
Additional Links
Substances : Wogonin
Diseases : Asthma
Pharmacological Actions : Anti-Asthmatic Agents, Anti-Inflammatory Agents, Interleukin-4 downregulation
[+]

These results show that the chondroprotective effects of wogonin are produced by its regulation of the gene expression.Aug 31, 2015

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Biomol Ther (Seoul). 2015 Sep ;23(5):442-8. Epub 2015 Sep 1. PMID: 26336584
Article Published Date : Aug 31, 2015
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Wogonin
Diseases : Osteoarthritis
Pharmacological Actions : Chondroprotective, Matrix metalloproteinase-3 (MMP-3) inhibitor
Additional Keywords : Gene Expression Regulation
[+]

Wogonin ameliorate complete Freund's adjuvant induced rheumatoid arthritis.Nov 11, 2019

Pubmed Data : Biofactors. 2019 Nov 12. Epub 2019 Nov 12. PMID: 31721330
Article Published Date : Nov 11, 2019
Study Type : Animal Study
Additional Links
Substances : Wogonin
Diseases : Rheumatoid Arthritis
Pharmacological Actions : Anti-Inflammatory Agents
[+]

Wogonin and 5-fluorouracil combination treatment caused a significant growth inhibition of human tumor xenografts in vivo.Jul 31, 2013

Pubmed Data : Biochem Cell Biol. 2013 Aug ;91(4):221-9. Epub 2013 Feb 14. PMID: 23859016
Article Published Date : Jul 31, 2013
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Wogonin
Diseases : Liver Cancer
Pharmacological Actions : Antiproliferative , Chemosensitizer, Cyclooxygenase 2 Inhibitors, Cyclooxygenase Inhibitors
Additional Keywords : Drug: 5-flourouracil, Natural Substance/Drug Synergy, Plant Extracts
[+]

Wogonin as a potential therapeutic candidate for the therapeutic strategy in colorectal cancer treatment.Dec 31, 2017

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Front Pharmacol. 2018 ;9:1356. Epub 2018 Nov 23. PMID: 30532707
Article Published Date : Dec 31, 2017
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Wogonin
Diseases : Colorectal Cancer
Pharmacological Actions : Antiproliferative , Apoptotic, Chemopreventive
[+]

Wogonin attenuates the deleterious effects of traumatic brain injury.Apr 04, 2019

Pubmed Data : Eur J Pharmacol. 2019 Apr 5 ;848:121-130. Epub 2019 Jan 25. PMID: 30689996
Article Published Date : Apr 04, 2019
Study Type : Animal Study
Additional Links
Substances : Wogonin
Diseases : Brain Injury: Traumatic
Pharmacological Actions : Neuroprotective Agents
[+]

Wogonin can attenuate liver fibrosis via regulating the activation and apoptosis of hepatic stellate cells.Jul 31, 2019

Pubmed Data : Int Immunopharmacol. 2019 Aug 1 ;75:105671. Epub 2019 Aug 1. PMID: 31377590
Article Published Date : Jul 31, 2019
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Wogonin
Diseases : Liver Fibrosis
Pharmacological Actions : Anti-Fibrotic, Apoptotic, Hepatoprotective
[+]

Wogonin can be a promising chemoprotective agent and might be useful to avert secondary leukemia and other drug related cancers.Aug 31, 2013

Pubmed Data : Food Chem Toxicol. 2013 Sep ;59:724-30. Epub 2013 Jul 17. PMID: 23872129
Article Published Date : Aug 31, 2013
Study Type : Animal Study
Additional Links
Substances : Wogonin
Diseases : DNA damage, Leukemia, Oxidative Stress
Pharmacological Actions : Anticarcinogenic Agents, Antioxidants, DNA Repair Up-regulation
Additional Keywords : Epigenetic Modification
Problem Substances : Etoposide
[+]

Wogonin can be developed into an efficient natural sensitizer for resistant human myelogenous leukemiaFeb 01, 2017

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Sci Rep. 2017 Feb 2 ;7:39950. Epub 2017 Feb 2. PMID: 28150717
Article Published Date : Feb 01, 2017
Study Type : Animal Study
Additional Links
Substances : Wogonin
Diseases : Cancers: Drug Resistant, Leukemia: Chronic myelogenous leukemia (CML)
Pharmacological Actions : Chemosensitizer
[+]

Wogonin combined with low-dose paclitaxel obtained the same efficacy as with high dose Paclitaxel reducing tumor burden by 61%.Sep 30, 2013

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Chin J Cancer Res. 2013 Oct ;25(5):505-13. PMID: 24255573
Article Published Date : Sep 30, 2013
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Wogonin
Diseases : Gastric Cancer
Pharmacological Actions : Antiproliferative , Apoptotic
Additional Keywords : Chemothapeutic Synergy: Paclitaxel, Natural Substance/Drug Synergy
[+]

Wogonin could suppress tumor growth and induce cell apoptosis by inhibiting the expression of NF-κB.Feb 20, 2017

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : BMC Cancer. 2017 Feb 21 ;17(1):147. Epub 2017 Feb 21. PMID: 28222771
Article Published Date : Feb 20, 2017
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Wogonin
Diseases : Lymphoma
Pharmacological Actions : Antiproliferative , Apoptotic, NF-kappaB Inhibitor
[+]

Wogonin effectively suppressed inflammation associated colon carcinogenesis and cancer development in mice.Dec 31, 2013

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Cell Death Dis. 2014 ;5:e1283. Epub 2014 Jun 5. PMID: 24901054
Article Published Date : Dec 31, 2013
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Wogonin
Diseases : Colorectal Cancer, Colorectal Cancer: Prevention
Pharmacological Actions : Anti Inflammatory, Antineoplastic Agents, Antiproliferative , Interleukin-1 beta downregulation, Interleukin-6 Downregulation, NF-kappaB Inhibitor, Nrf2 activation
[+]

Wogonin has anticancer activity in both ER-positive and -negative breast cancer cells. Feb 15, 2008

Pubmed Data : Int J Cancer. 2008 Feb 15;122(4):816-22. PMID: 17957784
Article Published Date : Feb 15, 2008
Study Type : Animal Study
Additional Links
Substances : Wogonin
Diseases : Breast Cancer
Pharmacological Actions : Antiproliferative , Apoptotic, Estrogen Receptor Modulators
[+]

Wogonin improves functional neuroprotection for acute cerebral ischemia.Oct 31, 2019

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Ann Transl Med. 2019 Nov ;7(22):639. PMID: 31930040
Article Published Date : Oct 31, 2019
Study Type : Animal Study
Additional Links
Substances : Wogonin
Diseases : Cerebral Ischemia
Pharmacological Actions : Neuroprotective Agents
[+]

Wogonin induced antiallergic effects in a murine model of allergic rhinitis.Dec 31, 2017

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Allergy Rhinol (Providence). 2018 Jan-Dec;9:2152656718764145. Epub 2018 Apr 9. PMID: 29977652
Article Published Date : Dec 31, 2017
Study Type : Animal Study
Additional Links
Substances : Wogonin
Diseases : Allergic Rhinitis
Pharmacological Actions : Anti-Inflammatory Agents
[+]

wogonin may be a promising multifunctional drug candidate for Alzheimer's disease.Dec 31, 2016

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Evid Based Complement Alternat Med. 2017 ;2017:3545169. Epub 2017 Jun 7. PMID: 28680449
Article Published Date : Dec 31, 2016
Study Type : Transgenic Animal Study
Additional Links
Substances : Wogonin
Diseases : Alzheimer's Disease
Pharmacological Actions : Neuroprotective Agents
[+]

Wogonin might be a potential therapeutic agent for NAFLD.May 05, 2017

Pubmed Data : Biomed Pharmacother. 2017 May 6 ;91:621-631. Epub 2017 May 6. PMID: 28486193
Article Published Date : May 05, 2017
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Wogonin
Diseases : Nonalcoholic fatty liver disease (NAFLD)
Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants, Interleukin-6 Downregulation, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

Wogonin mitigates intervertebral disc degeneration.Nov 30, 2018

Pubmed Data : Int Immunopharmacol. 2018 Dec ;65:539-549. Epub 2018 Nov 6. PMID: 30412851
Article Published Date : Nov 30, 2018
Study Type : Animal Study
Additional Links
Substances : Wogonin
Diseases : Degenerative Disk Disease
Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants, Interleukin-1 beta downregulation
[+]

Wogonin pre-treatment attenuates cisplatin-induced nephrotoxicity.May 15, 2019

Pubmed Data : Chem Biol Interact. 2019 May 16. Epub 2019 May 16. PMID: 31103702
Article Published Date : May 15, 2019
Study Type : Animal Study
Additional Links
Substances : Wogonin
Diseases : Chemotherapy-Induced Toxicity: Cisplatin
Pharmacological Actions : Chemoprotective Agents, Renoprotective
[+]

Wogonin prevents alcohol-induced gastric mucosal damage in rats. Aug 01, 2008

Pubmed Data : Appl Environ Microbiol. 2008 Aug;74(15):4650-5. Epub 2008 Jun 6. PMID: 15139485
Article Published Date : Aug 01, 2008
Study Type : Animal Study
Additional Links
Substances : Wogonin
Diseases : Alcohol Toxicity
Pharmacological Actions : Apoptotic, Cyclooxygenase 2 Inhibitors
[+]

Wogonin represses multiple myeloma stimulated angiogenesis and tumor progression.Dec 29, 2015

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Oncotarget. 2015 Dec 30. Epub 2015 Dec 30. PMID: 26735336
Article Published Date : Dec 29, 2015
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Wogonin
Diseases : Multiple Myeloma
Pharmacological Actions : Angiogenesis Inhibitors, Antiproliferative , Hypoxia inducible factor-1 alpha (HIF-1α) inhibitor
Additional Keywords : Natural Substance/Drug Synergy
[+]

Wogonin significantly sensitized resistant HNC cells to cisplatin both in vitro and in vivo. Aug 19, 2016

Pubmed Data : Apoptosis. 2016 Aug 20. Epub 2016 Aug 20. PMID: 27544755
Article Published Date : Aug 19, 2016
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Wogonin
Diseases : Cancers: Drug Resistant, Head and Neck Cancer
Pharmacological Actions : Chemosensitizer
Additional Keywords : Selective Cytotoxicity
[+]

Wogonin suppresses tumor cells migration in inflammatory microenvironment by inactivating STAT3 signaling.Jun 28, 2014

Pubmed Data : Mol Carcinog. 2014 Jun 29. Epub 2014 Jun 29. PMID: 24976450
Article Published Date : Jun 28, 2014
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Wogonin
Diseases : Lung Cancer, Lung Cancer: Metastatic
Pharmacological Actions : Anti-Inflammatory Agents, Anti-metastatic
Additional Keywords : Tumor Microenvironment
[+]

Wogonin treatment prevented leukemia development when given early after transplantation.Jan 10, 2018

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Haematologica. 2018 Jan 11. Epub 2018 Jan 11. PMID: 29326123
Article Published Date : Jan 10, 2018
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Wogonin
Diseases : Chronic Lymphocytic Leukemia
Pharmacological Actions : Anti-Inflammatory Agents, Chemotherapeutic
[+]

Wogonin, a compound found within Chinese Skullcap, prevents immunosuppressive action but not anti-inflammatory effect induced by glucocorticoid.Jul 01, 2008

Pubmed Data : Dig Dis Sci. 2008 Jul;53(7):1774-84. Epub 2008 Mar 27. PMID: 17404053
Article Published Date : Jul 01, 2008
Study Type : Animal Study
Additional Links
Substances : Chinese Skullcap , Wogonin
Diseases : Corticosteroid-Induced Toxicity
Pharmacological Actions : Anti-Inflammatory Agents, Apoptotic
[+]

This review is the succinct appraisal of the pertinent articles on the mechanisms of anti-tumor properties of wogonin.Dec 31, 2016

Pubmed Data : Chin J Nat Med. 2017 Jan ;15(1):15-40. PMID: 28259249
Article Published Date : Dec 31, 2016
Study Type : Review
Additional Links
Substances : Wogonin
Diseases : Cancers: All, Cancers: Drug Resistant
Pharmacological Actions : Anti-metastatic, Apoptotic, Tumor Suppressor Protein p53 Upregulation
Additional Keywords : Phytotherapy
[+]

A review of targeting oncogenic transcription factors by polyphenols.Jan 03, 2018

Pubmed Data : Pharmacol Res. 2018 Jan 4. Epub 2018 Jan 4. PMID: 29305909
Article Published Date : Jan 03, 2018
Study Type : Review
Additional Links
Substances : 4-Shogaol, 6-Shogaol, Apigenin, Berberine, Caffeic Acid, Capsaicin, Cardamonin, Chrysin, Curcumin, EGCG (Epigallocatechin gallate), Ellagic Acid, Fisetin, Gingerol , Luteolin, Mangiferin, Piperlongumine , Polyphenols, Pterostilbene, Quercetin, Resveratrol, Rutin, Sesamin, Ursolic Acid, Wogonin, Xanthohumol
Diseases : Cancers: All
Pharmacological Actions : Chemopreventive, Chemotherapeutic, Hypoxia inducible factor-1 alpha (HIF-1α) inhibitor, NF-kappaB Inhibitor, STAT3 Inhibitor, Wnt/β-catenin signaling pathway modulation
[+]

A review of the anti-cancer natural products isolated from Chinese medicinal herbs.Jul 21, 2011

Pubmed Data : Chin Med. 2011 Jul 22 ;6(1):27. Epub 2011 Jul 22. PMID: 21777476
Article Published Date : Jul 21, 2011
Study Type : Review
Additional Links
Substances : Artemisinin, Berberine, Beta-Elemene, Curcumin, Emodin, Flavonoids, Ginsenosides, Shikonin, Silibinin, Ursolic Acid, Wogonin
Diseases : Cancers: All
Pharmacological Actions : Chemopreventive, Chemotherapeutic
Additional Keywords : Traditional Chinese Medicine
[+]

A wogonin-rich-fraction of Scutellaria baicalensis root extract exerts chondroprotective effects.Mar 02, 2017

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Sci Rep. 2017 Mar 3 ;7:43789. Epub 2017 Mar 3. PMID: 28256567
Article Published Date : Mar 02, 2017
Study Type : In Vitro Study
Additional Links
Substances : Wogonin
Diseases : Osteoarthritis
Pharmacological Actions : Anti-Inflammatory Agents, Chondroprotective, Cyclooxygenase 2 Inhibitors, Interleukin-1 beta downregulation, Interleukin-6 Downregulation, Matrix Metalloproteinase-13 (MMP-13) Inhibitor, Matrix metalloproteinase-3 (MMP-3) inhibitor, Matrix metalloproteinase-9 (MMP-9) inhibitor
[+]

Anti-tumor and anti-metastatic actions of wogonin isolated from Scutellaria baicalensis roots through anti-lymphangiogenesis.Feb 14, 2013

Pubmed Data : Phytomedicine. 2013 Feb 15 ;20(3-4):328-36. Epub 2012 Dec 6. PMID: 23219337
Article Published Date : Feb 14, 2013
Study Type : In Vitro Study
Additional Links
Substances : Chinese Skullcap , Wogonin
Diseases : Osteosarcoma
Pharmacological Actions : Anti-metastatic, Cyclooxygenase 2 Inhibitors, VEGFR3 inhibition
Additional Keywords : Phytotherapy
[+]

Anticancer effect of nor-wogonin on human triple-negative breast cancer cells via downregulation. Mar 31, 2019

Pubmed Data : Pharmacol Rep. 2019 Apr ;71(2):289-298. Epub 2019 Jan 7. PMID: 30826569
Article Published Date : Mar 31, 2019
Study Type : In Vitro Study
Additional Links
Substances : Wogonin
Diseases : Breast Cancer: Triple Negative
Pharmacological Actions : Antiproliferative
[+]

Chemopreventive and anticancer activity of flavonoids and its possibility for clinical use by combining with conventional chemotherapeutic agents.Dec 31, 2018

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Am J Cancer Res. 2019 ;9(8):1517-1535. Epub 2019 Aug 1. PMID: 31497340
Article Published Date : Dec 31, 2018
Study Type : Review
Additional Links
Substances : Apigenin, Cyanidin, Delphinidin, Flavonoids, Kaempferol, Luteolin, Quercetin, Vitexins, Wogonin
Diseases : Cancers: All
Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants, Antiproliferative , Apoptotic, Chemopreventive, Chemosensitizer, Chemotherapeutic
[+]

Oridonin and wogonin may suppress ovarian cancer stem cells.Jan 01, 2012

Pubmed Data : Discov Med. 2012 Jan ;13(68):7-17. PMID: 22284780
Article Published Date : Jan 01, 2012
Study Type : In Vitro Study
Additional Links
Substances : Oridonin, Wogonin
Diseases : Cancer Stem Cells, Ovarian Cancer
Pharmacological Actions : Antiproliferative , EpCAM surface marker down-regulation
[+]

Phytochemical modulation of apoptosis and autophagy could be used to overcome chemoresistance in leukemic stem cells.Dec 31, 2016

Pubmed Data : Int Rev Neurobiol. 2017 ;135:249-278. Epub 2017 Apr 12. PMID: 28807161
Article Published Date : Dec 31, 2016
Study Type : Review
Additional Links
Substances : Chrysin, Curcumin, Resveratrol, Wogonin
Diseases : Acute lymphoblastic leukemia (ALL), Acute Myeloid Leukemia, Leukemia
Pharmacological Actions : Apoptotic, Autophagy Up-regulation
Additional Keywords : Cancer Stem Cells
[+]

Sustained cytotoxicity of wogonin on breast cancer cells by encapsulation in solid lipid nanoparticles.Mar 12, 2018

Pubmed Data : Nanomaterials (Basel). 2018 Mar 13 ;8(3). Epub 2018 Mar 13. PMID: 29533979
Article Published Date : Mar 12, 2018
Study Type : In Vitro Study
Additional Links
Substances : Wogonin
Diseases : Breast Cancer
Pharmacological Actions : Cytotoxic
[+]

The present data suggests a potential clinical impact of wogonin for ovarian cancer patients.Dec 31, 2016

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Biomed Res Int. 2017 ;2017:9381513. Epub 2017 Oct 18. PMID: 29181409
Article Published Date : Dec 31, 2016
Study Type : In Vitro Study
Additional Links
Substances : Wogonin
Diseases : Ovarian Cancer
Pharmacological Actions : Apoptotic, Bcl-2 protein down-regulation, Tumor Suppressor Protein p53 Upregulation, Vascular Endothelial Growth Factor Inhibitors
[+]

The present study demonstrated that wogonin treatment specifically exhibits cytotoxicity effect on lung cancer cells.Oct 08, 2019

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Balkan Med J. 2019 Oct 9. Epub 2019 Oct 9. PMID: 31594288
Article Published Date : Oct 08, 2019
Study Type : In Vitro Study
Additional Links
Substances : Wogonin
Diseases : Lung Cancer
Pharmacological Actions : Antiproliferative , Apoptotic
[+]

This review we have discussed recently discovered therapeutic potential of wogonin in the treatment of diabetic cardiomyopathy.Jul 07, 2019

Pubmed Data : Curr Pharm Des. 2019 Jul 8. Epub 2019 Jul 8. PMID: 31298148
Article Published Date : Jul 07, 2019
Study Type : Review
Additional Links
Substances : Wogonin
Diseases : Cardiomyopathy, Diabetic Complications
Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants, Cardioprotective
[+]

Wogonin acts as an ovary cancer cell proliferation inhibiting agent through activation of apoptosis.Nov 09, 2019

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Med Sci Monit. 2019 Nov 10 ;25:8465-8471. Epub 2019 Nov 10. PMID: 31707402
Article Published Date : Nov 09, 2019
Study Type : In Vitro Study
Additional Links
Substances : Wogonin
Diseases : Ovarian Cancer
Pharmacological Actions : Antiproliferative , Apoptotic, Cell cycle arrest
[+]

Wogonin affects proliferation and the energy metabolism of SGC-7901 and A549 cells.Dec 31, 2018

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Exp Ther Med. 2019 Jan ;17(1):911-918. Epub 2018 Nov 28. PMID: 30651880
Article Published Date : Dec 31, 2018
Study Type : In Vitro Study
Additional Links
Substances : Wogonin
Diseases : Gastric Cancer, Lung Cancer
Pharmacological Actions : Angiogenesis Inhibitors, Antiproliferative
[+]

Wogonin alleviates hyperglycemia through increased glucose entry into cells via AKT/GLUT4 pathway.Jul 21, 2019

Pubmed Data : Curr Pharm Des. 2019 Jul 22. Epub 2019 Jul 22. PMID: 31333118
Article Published Date : Jul 21, 2019
Study Type : In Vitro Study
Additional Links
Substances : Wogonin
Diseases : Diabetes Mellitus: Type 2, Hyperglycemia
Pharmacological Actions : Hypoglycemic Agents
[+]

Wogonin and chrysin may contribute to overcoming drug resistance in non-small cell lung cancer cells. May 01, 2007

Pubmed Data : Int J Cancer. 2007 May 1;120(9):2019-27. PMID: 17266043
Article Published Date : May 01, 2007
Study Type : In Vitro Study
Additional Links
Substances : Chrysin, Flavonoids, Wogonin
Diseases : Cancers: Drug Resistant, Lung Cancer, Non-Small-Cell Lung Carcinoma
Pharmacological Actions : Apoptotic, Cell cycle arrest, Interleukin-6 Downregulation
Additional Keywords : Drug: Doxorubicin
[+]

Wogonin attenuates inflammation by activating PPAR-γ in alcoholic liver disease.Aug 31, 2017

Pubmed Data : Int Immunopharmacol. 2017 Sep ;50:95-106. Epub 2017 Jun 21. PMID: 28646664
Article Published Date : Aug 31, 2017
Study Type : In Vitro Study
Additional Links
Substances : Wogonin
Diseases : Alcoholic Liver Disease
Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-6 Downregulation, NF-kappaB Inhibitor, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

Wogonin can be a potential therapeutic candidate for enhancing the efficacy of oxaliplatin in gastric cancer treatment.Jan 14, 2018

Pubmed Data : Phytomedicine. 2018 Jan 15 ;39:168-175. Epub 2017 Dec 18. PMID: 29433678
Article Published Date : Jan 14, 2018
Study Type : In Vitro Study
Additional Links
Substances : Wogonin
Diseases : Gastric Cancer
Pharmacological Actions : Chemosensitizer, Chemotherapeutic
Additional Keywords : Chemotherapeutic Synergy: Oxaliplatin
[+]

Wogonin could be a potential therapy for the treatment of age-related macular degeneration.Mar 31, 2017

Pubmed Data : Mol Med Rep. 2017 Apr ;15(4):2289-2295. Epub 2017 Feb 28. PMID: 28260013
Article Published Date : Mar 31, 2017
Study Type : In Vitro Study
Additional Links
Substances : Wogonin
Diseases : Macular Degeneration
Pharmacological Actions : Cyclooxygenase 2 Inhibitors, Interleukin-1 beta downregulation, Interleukin-6 Downregulation, Interleukin-8 downregulation
[+]

Wogonin could be an ideal candidate for increasing sorafenibs activity in hepatocellular carcinoma therapy.May 31, 2017

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Oncol Lett. 2017 Jun ;13(6):5028-5034. Epub 2017 Apr 20. PMID: 28599504
Article Published Date : May 31, 2017
Study Type : In Vitro Study
Additional Links
Substances : Wogonin
Diseases : Liver Cancer
Pharmacological Actions : Apoptotic, Autophagy Inhibitors
Additional Keywords : Chemothapeutic Synergy: Sorafenib
[+]

Wogonin could significantly increase the sensitivity of cisplatin-resistant ovarian cancer cells to cisplatin.Aug 11, 2019

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Med Sci Monit. 2019 Aug 12 ;25:6007-6014. Epub 2019 Aug 12. PMID: 31402794
Article Published Date : Aug 11, 2019
Study Type : In Vitro Study
Additional Links
Substances : Wogonin
Diseases : Ovarian Cancer
Pharmacological Actions : Apoptotic, Chemosensitizer
Additional Keywords : Chemotherapeutic Synergy: Cisplatin
[+]

Wogonin has a synergistic effect with 5-fluorouracil, etoposide, and adriamycin to enhance chemotherapy and reverse drug resistance.Dec 31, 2015

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Onco Targets Ther. 2016 ;9:2935-43. Epub 2016 May 17. PMID: 27274287
Article Published Date : Dec 31, 2015
Study Type : Review
Additional Links
Substances : Chinese Skullcap , Wogonin
Diseases : Cancers: All
Pharmacological Actions : Angiogenesis Inhibitors, Antiproliferative , Apoptotic, Chemosensitizer
Additional Keywords : Chemothapeutic Synergy: 5-flourouracil, Natural Substance/Drug Synergy
[+]

Wogonin has anti-hepatitis B virus effects. Nov 30, 2000

Pubmed Data : Planta Med. 2000 Dec ;66(8):694-8. PMID: 11199123
Article Published Date : Nov 30, 2000
Study Type : In Vitro Study
Additional Links
Substances : Wogonin
Diseases : Hepatitis B
Pharmacological Actions : Antiviral Agents
[+]

Wogonin has the ability to inhibit the proliferation of gastric cancer cells.May 31, 2016

Pubmed Data : Zhong Yao Cai. 2016 Jun ;39(6):1372-6. PMID: 30156810
Article Published Date : May 31, 2016
Study Type : In Vitro Study
Additional Links
Substances : Wogonin
Diseases : Gastric Cancer
Pharmacological Actions : Anti-metastatic, Antiproliferative , Apoptotic
[+]

Wogonin induces apoptosis and down-regulates survivin in human breast cancer MCF-7 cells.Jan 31, 2012

Pubmed Data : Int Immunopharmacol. 2012 Feb ;12(2):334-41. Epub 2011 Dec 17. PMID: 22182776
Article Published Date : Jan 31, 2012
Study Type : In Vitro Study
Additional Links
Substances : Wogonin
Diseases : Breast Cancer
Pharmacological Actions : Antineoplastic Agents, Antiproliferative , Apoptotic, Bcl-2 protein down-regulation, Cell cycle arrest, Tumor Suppressor Protein p53 Upregulation
[+]

Wogonin induces apoptosis of human osteosarcoma cancer stem cells.Jun 11, 2017

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : BMC Complement Altern Med. 2017 Jun 12 ;17(1):304. Epub 2017 Jun 12. PMID: 28606135
Article Published Date : Jun 11, 2017
Study Type : In Vitro Study
Additional Links
Substances : Wogonin
Diseases : Osteosarcoma
Pharmacological Actions : Apoptotic, Matrix metalloproteinase-9 (MMP-9) inhibitor
Additional Keywords : Cancer Stem Cells
[+]

Wogonin induces Beclin-1/PI3K and reactive oxygen species-mediated autophagy in human pancreatic cancer cells.Nov 30, 2016

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Oncol Lett. 2016 Dec ;12(6):5059-5067. Epub 2016 Nov 8. PMID: 28105213
Article Published Date : Nov 30, 2016
Study Type : In Vitro Study
Additional Links
Substances : Wogonin
Diseases : Pancreatic Cancer
Pharmacological Actions : Autophagy Up-regulation
[+]

Wogonin induces differentiation and cell cycle arrest in human leukemia cells. Sep 04, 2008

Pubmed Data : Eur J Pharmacol. 2008 Sep 4;591(1-3):7-12. Epub 2008 Jun 12. PMID: 18577379
Article Published Date : Sep 04, 2008
Study Type : In Vitro Study
Additional Links
Substances : Wogonin
Diseases : Leukemia
Pharmacological Actions : Cell cycle arrest
[+]

Wogonin induces programmed cell death in human ovarian cancer cells. Aug 01, 2003

Pubmed Data : Ai Zheng. 2003 Aug;22(8):801-5. PMID: 12917023
Article Published Date : Aug 01, 2003
Study Type : In Vitro Study
Additional Links
Substances : Wogonin
Diseases : Ovarian Cancer
Pharmacological Actions : Antiproliferative , Apoptotic
[+]

Wogonin inhibits cell cycle progression by activating the glycogen synthase kinase-3 beta in hepatocellular carcinoma.Jan 17, 2020

Pubmed Data : Phytomedicine. 2020 Jan 18 ;68:153174. Epub 2020 Jan 18. PMID: 31991293
Article Published Date : Jan 17, 2020
Study Type : In Vitro Study
Additional Links
Substances : Wogonin
Diseases : Liver Cancer
Pharmacological Actions : Antiproliferative , Cell cycle arrest, Cyclin D1 Down-Regulation
[+]

Wogonin inhibits the proliferation of myelodysplastic syndrome cells.Oct 31, 2015

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Mol Med Rep. 2015 Nov ;12(5):7285-92. Epub 2015 Sep 23. PMID: 26398525
Article Published Date : Oct 31, 2015
Study Type : In Vitro Study
Additional Links
Substances : Wogonin
Diseases : Myelodysplastic Syndrome
Pharmacological Actions : Antiproliferative , Apoptotic, Cell cycle arrest, Cyclin D1 Down-Regulation, P21 Activation
[+]

Wogonin intercalates with genomic DNA and exhibits protective effects in IL-1β stimulated osteoarthritis chondrocytes.Aug 24, 2017

Pubmed Data : Chem Biol Interact. 2017 Aug 25 ;274:13-23. Epub 2017 Jul 5. PMID: 28688942
Article Published Date : Aug 24, 2017
Study Type : In Vitro Study
Additional Links
Substances : Wogonin
Diseases : Osteoarthritis
Pharmacological Actions : Chondroprotective, Interleukin-1 beta downregulation
[+]

Wogonin might be a potent treatment option for disrupting the tumor metastasis that favours liver cancer development.Feb 10, 2018

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Molecules. 2018 Feb 11 ;23(2). Epub 2018 Feb 11. PMID: 29439451
Article Published Date : Feb 10, 2018
Study Type : In Vitro Study
Additional Links
Substances : Wogonin
Diseases : Liver Cancer
Pharmacological Actions : Anti-metastatic, Matrix metalloproteinase-9 (MMP-9) inhibitor
[+]

Wogonin possesses a potent anti-influenza activity.Dec 31, 2017

Pubmed Data : Acta Virol. 2018 ;62(1):78-85. PMID: 29521106
Article Published Date : Dec 31, 2017
Study Type : In Vitro Study
Additional Links
Substances : Wogonin
Diseases : Influenza A
Pharmacological Actions : Antiviral Agents
[+]

Wogonin protects against cisplatin-induced acute kidney injury.Dec 31, 2017

Pubmed Data : Lab Invest. 2018 Jan ;98(1):79-94. Epub 2017 Dec 4. PMID: 29200200
Article Published Date : Dec 31, 2017
Study Type : In Vitro Study
Additional Links
Substances : Wogonin
Diseases : Chemotherapy-Induced Toxicity: Cisplatin
Pharmacological Actions : Chemoprotective Agents, Renoprotective
[+]

Wogonin sensitizes TNF alpha-resistant leukemia cells to TNF alpha-induced programmed cell death. Dec 01, 2006

Pubmed Data : Blood. 2006 Dec 1;108(12):3700-6. Epub 2006 Aug 24. PMID: 16931628
Article Published Date : Dec 01, 2006
Study Type : In Vitro Study
Additional Links
Substances : Wogonin
Diseases : Leukemia
Pharmacological Actions : Apoptotic, NF-kappaB Inhibitor, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

Wogonin suppresses the LPS‑enhanced invasiveness of MDA‑MB‑231 breast cancer cells.Sep 30, 2018

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Int J Mol Med. 2018 Oct ;42(4):1899-1908. Epub 2018 Jul 12. PMID: 30015917
Article Published Date : Sep 30, 2018
Study Type : In Vitro Study
Additional Links
Substances : Wogonin
Diseases : Breast Cancer: Triple Negative
Pharmacological Actions : Anti-metastatic, Matrix metalloproteinase-9 (MMP-9) inhibitor
[+]

Wogonin was cytotoxic to HPV 16 cervical cancer cells SiHa and CaSki but not to HPV negative cells.Jul 31, 2013

Pubmed Data : Cell Biol Toxicol. 2013 Aug ;29(4):259-72. Epub 2013 Aug 18. PMID: 23955116
Article Published Date : Jul 31, 2013
Study Type : In Vitro Study
Additional Links
Substances : Flavonoids, Wogonin
Diseases : Cervical Cancer
Pharmacological Actions : Apoptotic, Cytotoxic, Tumor Suppressor Protein p53 Upregulation
Additional Keywords : Oncogene Proteins, Plant Extracts, Selective Cytotoxicity
[+]

Wogonin, a compound within Chinese Skullcap, attenuates the adverse side effects of glucocorticoid-induced changes, without reducing the drug's anti-inflammatory effects.Aug 01, 2007

Pubmed Data : J Pharmacol Sci. 2007 Aug;104(4):355-65. Epub 2007 Aug 10. PMID:17690528
Article Published Date : Aug 01, 2007
Study Type : In Vitro Study
Additional Links
Substances : Chinese Skullcap , Wogonin
Diseases : Steroid-Induced Toxicity
Additional Keywords : Drug Side Effect Attenuation
[+]

Wogonin, an active compound in Scutellaria baicalensis, induces apoptosis and reduces telomerase activity in the promyelocytic leukemia cells.Jan 01, 2010

Pubmed Data : Phytomedicine. 2010 Jan;17(1):47-54. Epub 2009 Jul 3. PMID: 19577445
Article Published Date : Jan 01, 2010
Study Type : In Vitro Study
Additional Links
Substances : Chinese Skullcap , Wogonin
Diseases : Promyelocytic leukemia
Pharmacological Actions : Apoptotic, Telomerase Inhibitor
[+]

Wogonoside might be a potential therapeutic agent for the treatment of tumor metastasis in breast cancer.Aug 02, 2017

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : J Exp Clin Cancer Res. 2017 Aug 3 ;36(1):103. Epub 2017 Aug 3. PMID: 28774312
Article Published Date : Aug 02, 2017
Study Type : In Vitro Study
Additional Links
Substances : Wogonin
Diseases : Breast Cancer, Breast Cancer: Triple Negative
Pharmacological Actions : Anti-metastatic, Antiproliferative , Matrix metalloproteinase-2 (MMP-2) inhibitor, Matrix metalloproteinase-9 (MMP-9) inhibitor

Copyright: radiantskies / 123RF Stock Photo

Print Options

Some features are currently member only features. If you are already a member, please login. Otherwise, click here to become a member.

This website is for information purposes only. By providing the information contained herein we are not diagnosing, treating, curing, mitigating, or preventing any type of disease or medical condition. Before beginning any type of natural, integrative or conventional treatment regimen, it is advisable to seek the advice of a licensed healthcare professional.

© Copyright 2008-2020 GreenMedInfo.com, Journal Articles copyright of original owners, MeSH copyright NLM.