Schizophrenia https://greenmedinfo.com/category/keywords/schizophrenia en Alpha-lipoic acid can improve plasma adiponectin levels and may play a potential role in the treatment of metabolic risk factor in patients with schizophrenia. https://greenmedinfo.com/article/alpha-lipoic-acid-can-improve-plasma-adiponectin-levels-and-may-play-potential n/a PMID:  J Med Food. 2017 Jan ;20(1):79-85. Epub 2016 Dec 23. PMID: 28009525 Abstract Title:  Effects of Alpha-Lipoic Acid Supplementation on Plasma Adiponectin Levels and Some Metabolic Risk Factors in Patients with Schizophrenia. Abstract:  Adiponectin is an adipocyte-derived plasma protein with insulin-sensitizing and anti-inflammatory properties and is suggested to be a biomarker of metabolic disturbances. The aim of this study was to investigate the effects of alpha-lipoic acid (ALA) on plasma adiponectin and some metabolic risk factors in patients with schizophrenia. The plasma adipokine levels (adiponectin and leptin), routine biochemical and anthropometric parameters, markers of oxidative stress, and the serum phospholipid fatty acid profile in eighteen schizophrenic patients at baseline, in the middle, and at the end of a 3-month long supplementation period with ALA (500 mg daily) were determined. A significant increase in the plasma adiponectin concentrations, as well as a decrease in fasting glucose and aspartate aminotransferase activity (AST), was found. Baseline AST activity was independently correlated with the adiponectin concentrations. Our data show thatALA can improve plasma adiponectin levels and may play a potential role in the treatment of metabolic risk factor in patients with schizophrenia. Future randomized controlled trials are needed to confirm these preliminary investigations. https://greenmedinfo.com/article/alpha-lipoic-acid-can-improve-plasma-adiponectin-levels-and-may-play-potential#comments Adiponectin: Low Levels Alpha-Lipoic Acid Schizophrenia Adiponectin upregulation Hypoglycemic Agents Adiponectin upregulation Adiponectin: Low Levels Alpha-Lipoic Acid Hypoglycemic Agents Schizophrenia Human Study Tue, 11 Jul 2017 21:20:10 +0000 greenmedinfo 150298 at https://greenmedinfo.com Are You Ready for Digital Pills? https://greenmedinfo.com/blog/are-you-ready-digital-pills <div class="copyright">This article is copyrighted by GreenMedInfo LLC, 2019<br/><strong><a href="/greenmedinfocom-re-post-guidelines">Visit our Re-post guidelines</a></strong></div><p class="rtecenter"><span style="font-size:14px;"><span style="font-family:verdana,geneva,sans-serif;"><img alt="" src="//cdn.greenmedinfo.com/sites/default/files/ckeditor/Sayer Ji/images/digital_pill_greenmedinfo.jpg" style="width: 600px; height: 400px;" title="Are You Ready for Digital Pills?" /></span></span></p> <p><span style="font-size:24px;"><em><strong>What could possibly go wrong with swallowing tracking microchips with already highly toxic pharmaceuticals?&nbsp;</strong></em></span></p><p><a href="https://greenmedinfo.com/blog/are-you-ready-digital-pills" target="_blank">read more</a></p> https://greenmedinfo.com/blog/are-you-ready-digital-pills#comments Bipolar Disorder Depression Psychiatric Disorders Schizophrenia Antidepressants Antipsychotic Drugs Chemical and Drug Toxicity Health Guide: Mental Health Are Psychiatric Drugs safe? big pharma bipolar disorder corruption in science Depression Digital Pills mental health psychiatric disorders Schizophrenia Tue, 27 Mar 2018 16:56:26 +0000 GMI Research Group 161718 at https://greenmedinfo.com Brahmi could be a new frontier of restoration and prevention of cognitive deficit in schizophrenia. https://greenmedinfo.com/article/brahmi-could-be-new-frontier-restoration-and-prevention-cognitive-deficit-schi n/a PMID:  Clin Exp Pharmacol Physiol. 2016 Dec ;43(12):1234-1242. PMID: 27562725 Abstract Title:  Bacopa monnieri (Brahmi) improved novel object recognition task and increased cerebral vesicular glutamate transporter type 3 in sub-chronic phencyclidine rat model of schizophrenia. Abstract:  Reduced vesicular glutamate transporter 1 (VGLUT1) and 2 (VGLUT2) indicate glutamatergic hypofunction leading to cognitive impairment in schizophrenia. However, VGLUT3 involvement in cognitive dysfunction has not been reported in schizophrenia. Brahmi (Bacopa monnieri) might be a new treatment and prevention for cognitive deficits in schizophrenia by acting on cerebral VGLUT3 density. We aimed to study cognitive enhancement- and neuroprotective-effects of Brahmi on novel object recognition and cerebral VGLUT3 immunodensity in sub-chronic (2 mg/kg, Bid, ip) phencyclidine (PCP) rat model of schizophrenia. Rats were assigned to three groups for cognitive enhancement effect study: Group 1, Control; Group 2, PCP administration; Group 3, PCP+Brahmi. A neuroprotective-effect study was also carried out. Rats were again assigned to three groups: Group 1, Control; Group 2, PCP administration; Group 3, Brahmi+PCP. Discrimination ratio (DR) representing cognitive ability was obtained from a novel object recognition task. VGLUT3 immunodensity was measured in the prefrontal cortex, striatum and cornu ammonis fields 1-3 (CA1-3) using immunohistochemistry. We found reduced DR in the PCP group, which occurred alongside VGLUT3 reduction in all brain areas. PCP+Brahmi showed higher DR score with increased VGLUT3 immunodensity in the prefrontal cortex and striatum. Brahmi+PCP group showed a higher DR score with increased VGLUT3 immunodensityin the prefrontal cortex, striatum and CA1-3. We concluded that reduced cerebral VGLUT3 was involved in cognitive deficit in PCP-administrated rats. Receiving Brahmi after PCP restored cognitive deficit by increasing VGLUT3 in the prefrontal cortex and striatum. Receiving Brahmi before PCP prevented cognitive impairment by elevating VGLUT3 in prefrontal cortex, striatum and CA1-3. Therefore, Brahmi could be a new frontier of restoration and prevention of cognitive deficit in schizophrenia. https://greenmedinfo.com/article/brahmi-could-be-new-frontier-restoration-and-prevention-cognitive-deficit-schi#comments Bacopa Cognitive Decline/Dysfunction Schizophrenia Neuroprotective Agents Bacopa Cognitive Decline/Dysfunction Neuroprotective Agents Plant Extracts Schizophrenia Animal Study Wed, 28 Dec 2016 00:02:01 +0000 greenmedinfo 141074 at https://greenmedinfo.com Bread and Other Edible Agents of Mental Disease https://greenmedinfo.com/blog/bread-and-other-edible-agents-mental-disease <div class="copyright">This article is copyrighted by GreenMedInfo LLC, 2016<br/><strong><a href="/greenmedinfocom-re-post-guidelines">Visit our Re-post guidelines</a></strong></div><div> <p class="rtecenter"><img alt="Bread and Other Edible Agents of Mental Disease" src="//cdn.greenmedinfo.com/sites/default/files/ckeditor/lrossi/images/bread_mental_disease_greenmedinfo.png" style="width: 640px; height: 426px;" /></p> <p class="rtecenter"><strong>Originally published on <a href="http://journal.frontiersin.org/article/10.3389/fnhum.2016.00130/full" target="_blank">fronteirsin.org</a>.</strong></p><p><a href="https://greenmedinfo.com/blog/bread-and-other-edible-agents-mental-disease" target="_blank">read more</a></p> https://greenmedinfo.com/blog/bread-and-other-edible-agents-mental-disease#comments Anorexia Celiac Disease Mental Disorders Schizophrenia Dark Side of Wheat Gluten Wheat Bread and Other Edible Agents of Mental Disease Celiac Disease Gluten mental disorders Schizophrenia Wheat Thu, 14 Apr 2016 00:56:53 +0000 GMI reporter 125976 at https://greenmedinfo.com Euthanasia: Last Stop for Depression? https://greenmedinfo.com/blog/euthanasia-last-stop-depression <p class="rtecenter"><img alt="Euthanasia: Last Stop for Depression?" src="//cdn.greenmedinfo.com/sites/default/files/ckeditor/lrossi/images/euthanasia_depression_greenmedinfo.jpg" style="width: 600px; height: 314px;" title="Euthanasia: Last Stop for Depression?" /><br /> <span style="font-size:12px;"><strong><span style="letter-spacing: 0px;">Originally published on </span><strong style="letter-spacing: 0px;"><a href="https://kellybroganmd.com/euthanasia-last-stop-for-depression/?utm_source=Kelly+Brogan+MD+Newsletter&amp;utm_campaign=2e7ca768d4-Euthanasia%3A+Last+Stop+for+Depression&amp;utm_medium=email&amp;utm_term=0_d0f977a8c5-2e7ca768d4-108362245#" target="_blank" title="Euthanasia: Last Stop for Depression?">KellyBroganMD.com</a></strong></strong></span></p><p><a href="https://greenmedinfo.com/blog/euthanasia-last-stop-depression" target="_blank">read more</a></p> https://greenmedinfo.com/blog/euthanasia-last-stop-depression#comments Depression Schizophrenia Health Guide: Mental Health a mind of your own Euthanasia: Last Stop for Depression? mental illness psychiatry Schizophrenia Suicide Thu, 29 Dec 2016 20:56:58 +0000 drbrogan 141149 at https://greenmedinfo.com How Stress, Magnesium and Disease Are Linked https://greenmedinfo.com/blog/how-stress-magnesium-and-disease-are-linked <div class="copyright">This article is copyrighted by GreenMedInfo LLC, 2015<br/><strong><a href="/greenmedinfocom-re-post-guidelines">Visit our Re-post guidelines</a></strong></div><p class="rtecenter"><img alt="Stress, Magnesium and Disease" src="//cdn.greenmedinfo.com/sites/default/files/ckeditor/Sayer Ji/images/magnesium_stress.jpg" style="line-height: 24.4799995422363px; font-size: 0.9em; width: 600px; height: 400px;" /></p> <p><span style="font-size:18px;"><em><strong><span style="line-height: 24.4799995422363px;">In the Age of Toxicity one of the most common deficiencies and most life-threatening is magnesium. The good news is that it is easy to remedy...</span></strong></em></span></p> <p class="rtecenter">&nbsp;<a href="http://drsircus.com/medicine/magnesium/stress-magnesium-disease" rel="nofollow" target="_blank">Stress, Magnesium &amp; Disease</a></p><p><a href="https://greenmedinfo.com/blog/how-stress-magnesium-and-disease-are-linked" target="_blank">read more</a></p> https://greenmedinfo.com/blog/how-stress-magnesium-and-disease-are-linked#comments Insomnia Magnesium Magnesium Deficiency Health Guide: Mental Health Heart Health Men's Health Selective Serotonin Reuptake Inhibitors (SSRIs) Sexual Health Women's Health Anxiety bipolar disorder Depression Diabetes Heart Attack high blood pressure insomnia Magnesium Schizophrenia Stress Mon, 18 Feb 2013 13:00:00 +0000 drsircus 88811 at https://greenmedinfo.com T. gondii serointensity was associated with history of suicidal behaviour in younger patients. https://greenmedinfo.com/article/t-gondii-serointensity-was-associated-history-suicidal-behaviour-younger-patie n/a PMID:  Schizophr Res. 2011 Dec ;133(1-3):150-5. Epub 2011 Sep 3. PMID: 21890329 Abstract Title:  Toxoplasma gondii antibody titers and history of suicide attempts in patients with schizophrenia. Abstract:  Toxoplasma gondii (T. gondii) a widespread neurotropic parasite, has been previously associated with schizophrenia and more recently with suicidal behavior. However, no previous study has examined the association of T. gondii with suicidal behavior in schizophrenia patients. 950 individuals diagnosed with schizophrenia by SCID were recruited from the Munich area of Germany. Solid-enzyme immunoassay methods were used to measure IgG plasma antibodies to T. gondii, other neurotropic pathogens and gliadin. Logistic regression models were developed to analyze the association of T. gondii seropositivity or serointensity with history of suicidal behavior. In those younger than the median age of the sample, 38, T. gondii serointensity was associated with history of suicidal behavior (p = 0.02), while in the older patients the relationship was not significant (p = 0.21). Seropositivity was also associated with history of suicide attempt in younger patients, odds ratio 1.59 (95% CI 1.06 to 2.40), p = 0.03. Seropositivity for CMV (p = 0.22), HSV-1 (p = 0.36) and gliadin (p = 0.92) was not related to history of suicide attempt in the entire sample or any age subgroup. T. gondii serology might become, with interaction with vulnerability genes, a candidate biomarker for a subgroup of schizophrenia patients prone to attempting suicide. https://greenmedinfo.com/article/t-gondii-serointensity-was-associated-history-suicidal-behaviour-younger-patie#comments Schizophrenia Suicidal Behavior Risk Factors Schizophrenia Suicidal Behavior T. gondii serointensity Human Study Mon, 27 Feb 2017 18:18:31 +0000 greenmedinfo 144123 at https://greenmedinfo.com Top 5 Ways to Improve Your Mental Wellness https://greenmedinfo.com/blog/top-5-ways-improve-your-mental-wellness <div class="copyright">This article is copyrighted by GreenMedInfo LLC, 2019<br/><strong><a href="/greenmedinfocom-re-post-guidelines">Visit our Re-post guidelines</a></strong></div><p class="rtecenter"><img alt="" src="//cdn.greenmedinfo.com/sites/default/files/ckeditor/Sayer Ji/images/53610883_m.jpg" style="width: 600px; height: 400px;" /><br /> <strong><span style="font-size:12px;">Originally published on <a href="https://www.thedempsterclinic.com/top-5-ways-to-improve-your-mental-wellness/" rel="dofollow" target="_blank">The Dempster&nbsp;Clinic</a></span></strong></p> <p><span style="font-size:18px;"><em><strong>Traditionally, many conditions labeled under the umbrella of 'mental illness' were summed up solely as genetic or biochemical imbalances. Modern advances in psychiatric medicine have found causation to be more and more integrated to lifestyle and environmental factors, often finding the fundamental cause to be multi-factorial</strong></em></span></p><p><a href="https://greenmedinfo.com/blog/top-5-ways-improve-your-mental-wellness" target="_blank">read more</a></p> https://greenmedinfo.com/blog/top-5-ways-improve-your-mental-wellness#comments ADD Anxiety Autism Depression Schizophrenia Exercise Health Guide: Mental Health Meditation sleep Yoga ADD Addiction Autism Depression Schizophrenia Top 5 Ways To Improve Your Mental Wellness Sun, 24 Sep 2017 13:26:50 +0000 drdempster 119056 at https://greenmedinfo.com What If A Vitamin Could Have Saved Robin Williams? https://greenmedinfo.com/blog/what-if-vitamin-could-have-saved-robin-williams <div class="copyright">This article is copyrighted by GreenMedInfo LLC, 2014<br/><strong><a href="/greenmedinfocom-re-post-guidelines">Visit our Re-post guidelines</a></strong></div><p class="rtecenter"><br /> <img alt="What If A Vitamin Could Have Saved Robin Williams? " src="//cdn.greenmedinfo.com/sites/default/files/ckeditor/stebu/images/Robin_Williams_in_2008.jpg" style="width: 400px; height: 308px;" /></p> <p><span style="font-size:16px;"><strong><em>Robin Williams' health history would have made him a perfect candidate for Hoffer's high-dose niacin therapy. But would this therapy been better than the "best" drugs available to Williams?</em></strong></span></p> <p>Robin Williams' suicide death was shocking and surprising, until his health problems were made public. He'd been diagnosed with <strong><a href="/disease/depression">depression</a></strong> and <strong><a href="/disease/parkinsons-disease">Parkinson's disease</a></strong> in addition to having had a history of alcoholism and recreational drug abuse. And he had surgery in 2009 for a heart condition.</p><p><a href="https://greenmedinfo.com/blog/what-if-vitamin-could-have-saved-robin-williams" target="_blank">read more</a></p> https://greenmedinfo.com/blog/what-if-vitamin-could-have-saved-robin-williams#comments Alcoholism Depression Niacin Parkinson's Disease Schizophrenia Vitamin C Statin alcoholism American Psychiatric Association Depression Merck Niacin Parkinson's disease Robin Williams Schizophrenia Statin Suicide Vitamin C Tue, 21 Oct 2014 18:09:31 +0000 williamconder 115092 at https://greenmedinfo.com