QUERCETIN https://greenmedinfo.com/category/keywords/quercetin en 8 Healing Properties of Strawberries https://greenmedinfo.com/blog/8-healing-properties-strawberries <div class="copyright">This article is copyrighted by GreenMedInfo LLC, 2023<br/><strong><a href="/greenmedinfocom-re-post-guidelines">Visit our Re-post guidelines</a></strong></div><p class="rtecenter"><img alt="8 Juicy Reasons to Eat More Strawberries" src="//cdn.greenmedinfo.com/sites/default/files/ckeditor/stebu/images/Strawberries1.jpg" style="width: 500px; height: 333px;" /></p> <p><strong><span style="font-size:18px;"><em>Who doesn't love <a href="/substance/strawberry" rel="dofollow" target="_blank">strawberries</a>? And you don't need any reason other than the pleasure of their sweetness to eat them every day. But according to researchers from Oklahoma State University, there's lots more to strawberries than the flavor.</em></span><a href="#_edn1" name="_ednref1" title="">[i]</a></strong></p> <p>Their study was <strong><a href="https://www.ncbi.nlm.nih.gov/pubmed/24345049" rel="nofollow" target="_blank">published in the journal <em>Critical Reviews in Food Science and Nutrition</em></a></strong> with funding from the NIH and the California Strawberry Commission. In it the researchers review over 130 studies attesting to the strawberry's status as a "functional food."</p><p><a href="https://greenmedinfo.com/blog/8-healing-properties-strawberries" target="_blank">read more</a></p> https://greenmedinfo.com/blog/8-healing-properties-strawberries#comments Alzheimer's Disease Anthocyanins Blackberry C-Reactive Protein (CRP) Cancer Cardiovascular Diseases Carotenoids Catechin Ellagic Acid Flavonoids Hyperglycemia Hyperlipidemia Hypertension Kaempferol Naringenin Parkinson's Disease Phytosterols Polyphenols Potassium Quercetin Strawberry Vitamin C Vitamin E Antioxidants Health Guide: Farm/Pharma Face Off Health Guides: Healing Foods Alzheimer's disease Anthocyanins Antioxidants blackberry C-Reactive Protein (CRP) Cancer Cardiovascular Diseases CAROTENOIDS Catechin Ellagic Acid Flavonoids hyperglycemia hyperlipidemia hypertension Kaempferol Naringenin Parkinson's disease phytosterols POLYPHENOLS potassium QUERCETIN Strawberry Vitamin C VITAMIN E Sat, 18 Feb 2023 17:30:10 +0000 GMI Research Group 114933 at https://greenmedinfo.com If You're Concerned About Breast Cancer...What You Must Know https://greenmedinfo.com/blog/if-youre-concerned-about-breast-cancerwhat-you-must-know <div class="copyright">This article is copyrighted by GreenMedInfo LLC, 2019<br/><strong><a href="/greenmedinfocom-re-post-guidelines">Visit our Re-post guidelines</a></strong></div><p class="rtecenter"><img alt="" src="//cdn.greenmedinfo.com/sites/default/files/ckeditor/blank.justin/images/If_Youre_Concerned_About_Breast_Cancer-GreenMedInfo.jpg" style="width: 600px; height: 314px;" /></p> <p>As most of us know, October is Breast Cancer Awareness month. Dr. Helayne Waldman is the co-author (with Dr. Ed Bauman) of a new book called THE WHOLE FOOD GUIDE FOR BREAST CANCER SURVIVORS. According to the authors, the book is not just for survivors of cancer, but for anyone who wants to reduce their chances of becoming a cancer statistic in the first place. In honor of Breast Cancer Awareness month, Drs. Waldman and Bauman have allowed us to share a chapter from their book, which we're proud to reprint here at GreenMedInfo. For further info about this wonderful resource, check out <strong><a href="https://www.wholefoodguideforbreastcancer.com" rel="nofollow" target="_blank">www.<wbr />wholefoodguideforbreastcancer.<wbr />com</a></strong>.</p><p><a href="https://greenmedinfo.com/blog/if-youre-concerned-about-breast-cancerwhat-you-must-know" target="_blank">read more</a></p> https://greenmedinfo.com/blog/if-youre-concerned-about-breast-cancerwhat-you-must-know#comments Breast Cancer Breast Cancer: Ductal Carcinoma In Situ Breast Cancer: Prevention Broccoli Sprouts Cruciferous Vegetables Estrogen Dysregulation: 2/4/16 hydroxyestrone ratios Inflammation Quercetin Turmeric Health Guide: Breast Cancer Breast Cancer Broccoli Sprouts Cruciferous Vegetables QUERCETIN Turmeric Wed, 17 Oct 2012 15:00:00 +0000 helayne.waldman 82908 at https://greenmedinfo.com Naringenin-induced enhanced antioxidant defence system meliorates cholinergic neurotransmission and consolidates memory in male rats. https://greenmedinfo.com/article/naringenin-induced-enhanced-antioxidant-defence-system-meliorates-cholinergic- n/a PMID:  Life Sci. 2017 Dec 26. Epub 2017 Dec 26. PMID: 29287782 Abstract Title:  Naringenin-induced enhanced antioxidant defence system meliorates cholinergic neurotransmission and consolidates memory in male rats. Abstract:  AIMS: Free radical mediated neurotoxicity is a leading cause of neurodegenerative disorders. Neurodegeneration due to oxidative stress can produce cognitive dysfunctions. Flavonoids and curcuminoids are naturally occurring polyphenolic compounds that display a variety of therapeutic importance against oxidative stress. MAIN METHODS: This study was designed to assess potential role of polyphenolic compounds in neurocognitive functions and prevention against oxidative stress. For this purpose, young rats were orally treated with naringenin (NAR), curcumin (CUR) and quercetin (QUE) at a dose of 50mg/kg, 200mg/kg and 50mg/kg respectively for 16days. At 4th day of drug administration cognitive functions were monitored by Morris water maze test. In MWM cognitive functions in terms of learning acquisition (1h after training), retention (24h after training), memory extinction (4days after training), and reconsolidation (8 and 12days after training) were monitored. Biochemical and neurochemical analysis were done in whole brain. KEY FINDINGS: Treatment of NAR, CUR and QUE significantly enhanced learning acquisition, memory retention and reconsolidation and prevented memory extinction. Treatment of NAR and QUE prevented the alteration of brain antioxidant defence system by enhancing antioxidant enzyme activities and increasing antioxidant compound concentration. Oxidative stress in terms of lipid peroxidation was significantly prevented in treated rats. Serotonergic and cholinergic improvement was also found in treated rats. SIGNIFICANCE: The present study therefore provides biological evidence supporting the usefulness of these polyphenolic compounds in daily life for improvement of cognitive abilities and hence may have a potential role in the management of dementia and related disorders. https://greenmedinfo.com/article/naringenin-induced-enhanced-antioxidant-defence-system-meliorates-cholinergic-#comments Curcumin Naringenin Neurodegenerative Diseases Quercetin Antioxidants Neuroprotective Agents Antioxidants CURCUMIN Naringenin Neurodegenerative diseases Neuroprotective Agents QUERCETIN Animal Study Tue, 23 Jan 2018 18:16:18 +0000 greenmedinfo 158696 at https://greenmedinfo.com Quercetin attenuates the injury-induced reduction of γ-enolase expression in a middle cerebral artery occlusion model. https://greenmedinfo.com/article/quercetin-attenuates-injury-induced-reduction-enolase-expression-middle-cerebr n/a PMID:  Lab Anim Res. 2017 Dec ;33(4):308-314. Epub 2017 Dec 31. PMID: 29399028 Abstract Title:  Quercetin attenuates the injury-induced reduction ofγ-enolase expression in a middle cerebral artery occlusion animal model. Abstract:  Quercetin, a natural flavonoid, copiously exists in vegetable, fruits and tea. Quercetin is beneficial to neurodegenerative disorders via its strong anti-oxidant and anti-inflammatory activities.γ-Enolase is one of the enzymes of glycolytic pathway and is predominantly expressed in neuronal cells. The aim of the present study is to verify whether quercetin modulates the expression of γ-enolase in brain ischemic injury. Adult Sprague-Dawley male rats were subjected to middle cerebral artery occlusion (MCAO) and quercetin (50 mg/kg) or vehicle was administered by intraperitoneal injection at 1 h before MCAO onset. A proteomics study, Western blot analysis, reversetranscription-PCR, and immunofluorescence staining were conducted to investigate the change of γ-enolase expression level.We identified a decline in γ-enolase expression in MCAO-operated animal model using a proteomic approach. However, quercetin treatment significantly attenuated this decline. These results were confirmed using Western blot analysis, reverse transcription-PCR, and immunofluorescence staining techniques. γ-Enolase is accepted as a neuron specific energy synthesis enzyme, and quercetin modulates γ-enolase in a MCAO animal model. Thus, our findings can suggest the possibility that quercetin regulates γ-enolase expression in response to cerebral ischemia, which likely contributes to the neuroprotective effect of quercetin. https://greenmedinfo.com/article/quercetin-attenuates-injury-induced-reduction-enolase-expression-middle-cerebr#comments Cerebral Ischemia Quercetin Neuroprotective Agents Cerebral Ischemia Neuroprotective Agents QUERCETIN Animal Study Thu, 08 Feb 2018 04:12:16 +0000 greenmedinfo 159494 at https://greenmedinfo.com Quercetin can efficiently prevent stress induced neurological complications by rescuing brain from oxidative and inflammatory stress. https://greenmedinfo.com/article/quercetin-can-efficiently-prevent-stress-induced-neurological-complications-re n/a PMID:  Physiol Behav. 2017 Mar 15 ;171:69-78. Epub 2017 Jan 7. PMID: 28069457 Abstract Title:  Quercetin prevents chronic unpredictable stress induced behavioral dysfunction in mice by alleviating hippocampal oxidative and inflammatory stress. Abstract:  It is now evident that chronic stress is associated with anxiety, depression and cognitive dysfunction and very few studies have focused on identifying possible methods to prevent these stress-induced disorders. Previously, we identified abundance of quercetin in Urtica dioica extract, which efficiently attenuated stress related complications. Therefore, current study was designed to investigate the effect of quercetin on chronic unpredicted stress (CUS) induced behavioral dysfunction, oxidative stress and neuroinflammation in the mouse hippocampus. Animals were subjected to unpredicted stress for 21days, during which 30mg/kg quercetin was orally administered to them. Effect of CUS and quercetin treatment on animal behavior was assessed between day 22-26. Afterward, the hippocampus was processed to evaluate neuronal damage, oxidative and inflammatory stress. Results revealed that stressed animals were highly anxious (Elevated Plus Maze and Open Field), showed depressive-like behavior (sucrose preference task), performed poorly in short-term and long-term associative memory task (passive avoidance step-through task) and displayed reduced locomotion (open field). Quercetin alleviated behavioral dysfunction in chronically stressed animals. Compared to CUS, quercetin treatment significantly reduced anxiety, attenuated depression, improved cognitive dysfunction and normalized locomotor activity. Further, CUS elevated the levels of oxidative stress markers (TBARS, nitric oxide), lowered antioxidants (total thiol, catalase), enhanced expression of pro-inflammatory cytokines (IL-6, TNF-α, IL-1β and COX-2) in the hippocampus and damaged hippocampal neurons. Quercetin treatment significantly lowered oxidative and inflammatory stress and prevented neural damage. In conclusion, quercetin can efficiently prevent stress induced neurological complications by rescuing brain from oxidative and inflammatory stress. https://greenmedinfo.com/article/quercetin-can-efficiently-prevent-stress-induced-neurological-complications-re#comments Brain: Oxidative Stress Nettle Oxidative Stress Quercetin Anti-Inflammatory Agents Antioxidants Cyclooxygenase 2 Inhibitors Interleukin-6 Downregulation Tumor Necrosis Factor (TNF) Alpha Inhibitor Anti-Inflammatory Agents Antioxidants Brain: Oxidative Stress nettle oxidative stress QUERCETIN Animal Study Sat, 02 Sep 2017 01:10:24 +0000 greenmedinfo 152627 at https://greenmedinfo.com Quercetin protects both goat sperm and preimplantation embryos from cadmium-induced oxidative stress. https://greenmedinfo.com/article/quercetin-protects-both-goat-sperm-and-preimplantation-embryos-cadmium-induced n/a PMID:  Biol Trace Elem Res. 2018 Feb 4. Epub 2018 Feb 4. PMID: 29397540 Abstract Title:  Protective Effects of Quercetin Against Cadmium Chloride-Induced Oxidative Injury in Goat Sperm and Zygotes. Abstract:  Quercetin, a plant-derived flavonoid, is frequently used as an antioxidant for efficient anti-oxidative capacity. However, whether quercetin has protective effects on goat sperm and preimplantation embryos against Cd2+-induced oxidative injury is still unclear. So, we researched the influence of quercetin on goat sperm and zygotes respectively under the oxidative stress induced by Cd2+. In our study, quercetin decreased the malonaldehyde (MDA) and reactive oxygen species (ROS) levels caused by Cd2+ in goat sperm (p &lt; 0.05), which facilitated sperm characteristics including motility, survival rates, membrane integrity, and mitochondria activity during storage in vitro and subsequent embryo development (p &lt; 0.05). Moreover, in goat zygotes, quercetin decreased peroxidation products including ROS, MDA, and carbonyl through preserving or maintaining mitochondrial function, gene expression, and anti-oxidative products such as glutathione peroxidase, superoxide dismutase, and catalase, which amelioratedsubsequent embryo development and embryo quality (p &lt; 0.05). Taken together, these results suggest that quercetin protects both goat sperm and preimplantation embryos from Cd2+-induced oxidative stress. https://greenmedinfo.com/article/quercetin-protects-both-goat-sperm-and-preimplantation-embryos-cadmium-induced#comments Quercetin Testicular Injury: Cadmium-Induced Antioxidants Cadmium Antioxidants QUERCETIN Testicular Injury: Cadmium-Induced In Vitro Study Thu, 08 Feb 2018 04:18:59 +0000 greenmedinfo 159495 at https://greenmedinfo.com Quercetrin from Toona sinensis leaves induces cell cycle arrest and apoptosis in human colorectal cancer SW620 cells. https://greenmedinfo.com/article/quercetrin-toona-sinensis-leaves-induces-cell-cycle-arrest-and-apoptosis-human n/a PMID:  Oncol Rep. 2017 Dec ;38(6):3319-3326. Epub 2017 Oct 17. PMID: 29039609 Abstract Title:  Quercetrin from Toona sinensis leaves induces cell cycle arrest and apoptosis via enhancement of oxidative stress in human colorectal cancer SW620 cells. Abstract:  Finding effective strategies against colorectal cancer (CRC) is still an emergent health problem. In the present study, we investigated the anticancer activity of quercetrin from Toona sinensis leaves (QTL) and explored the underlying mechanism in human CRC cell line SW620. The cells were treated with various concentrations of QTL and the cytotoxic effects of QTL were determined using the MTT assay. Apoptosis and cell cycle status were detected by flow cytometry. Reactive oxygenspecies (ROS) levels and mitochondrial membrane potential (∆Ψm) were assessed using DCF-DA and JC-1 fluorescence spectrophotometry, respectively. Western blot analysis was used to quantify the expression of apoptosis‑related proteins. RT-PCR was applied to determine the mRNA levels of glutathione peroxidase (GPx) and catalase (CAT). QTL exhibited growth inhibitory effects and caused cell cycle arrest in the G2/M phase, which was accompanied by increased expression of p53 and p21 proteins. QTL promoted apoptosis which was consistent with the upregulated expression of Bax, cytochrome c,caspase-9, Apaf-1 and caspase-3. In addition, QTL induced the loss of mitochondrial membrane potential and triggered ROS generation, as revealed by the downregulated mRNA expression and enzymatic activity of GPx and CAT. Furthermore, both N‑acetyl cysteine (NAC) and GSH attenuated the QTL-inducedgrowth inhibition observed in SW620 cells along with the increase of ROS levels. These findings revealed that QTL inhibited the growth of CRC cells and facilitated apoptosis by enhancing oxidative stress. QTL may therefore have potential for use in CRC chemotherapy. https://greenmedinfo.com/article/quercetrin-toona-sinensis-leaves-induces-cell-cycle-arrest-and-apoptosis-human#comments Colorectal Cancer Quercetin Toona sinensis Antiproliferative Apoptotic Antiproliferative Apoptotic COLORECTAL CANCER QUERCETIN Toona sinensis In Vitro Study Sat, 10 Mar 2018 02:10:19 +0000 greenmedinfo 160999 at https://greenmedinfo.com The neuroprotective effects of quercetin may be at least partly due to its inducing effects on the expression levels of the BDNF mRNA. https://greenmedinfo.com/article/neuroprotective-effects-quercetin-may-be-least-partly-due-its-inducing-effects n/a PMID:  Bratisl Lek Listy. 2018 ;119(1):28-31. PMID: 29405727 Abstract Title:  Effect of quercetin on the brain-derived neurotrophic factor gene expression in the rat brain. Abstract:  INTRODUCTION: Quercetin is a ubiquitous flavonoid found in many plants. Neuroprotective effects of quercetin have been shown in several in vitro and in vivo studies, but its mechanism of action has not been fully defined yet. Brain-derived neurotrophic factor (BDNF) is a fundamental neurotrophin with vital functions in the survival of neuronal cells. In the present study, we aimed to investigate the effects of quercetin on expression of BDNF mRNA in the hippocampus of rat brain. METHODS: Male rats were daily gavaged with quercetin (10, 20 or 50 mg/kg·bwt) for 30 days. Hippocampal levels of the BDNF transcripts were assessed using quantitative (q) RT-PCR. RESULTS: Quercetin at doses of 20 and 50 mg/kg caused a significant increase in the mRNA expression of BDNF as compared with the control group. Quercetin treatment at a dose of 10 mg/kg failed to cause any significant changes in the levels of BDNF mRNA CONCLUSION: Our findings suggest that the neuroprotective effects of quercetin may be at least partly due to its inducing effects on the expression levels of the BDNF mRNA (Fig. 1, Ref. 40). https://greenmedinfo.com/article/neuroprotective-effects-quercetin-may-be-least-partly-due-its-inducing-effects#comments Quercetin Brain-derived neurotrophic factor modulator Neuroprotective Agents Brain-derived neurotrophic factor modulator Neuroprotective Agents QUERCETIN Animal Study Thu, 08 Feb 2018 04:05:01 +0000 greenmedinfo 159491 at https://greenmedinfo.com