Spermatogenic Failure https://greenmedinfo.com/category/disease/spermatogenic-failure en BPA affected human sperm integrity by inducing pro-oxidative and apoptotic mitochondrial dysfunction. https://greenmedinfo.com/article/bpa-affected-human-sperm-integrity-inducing-pro-oxidative-and-apoptotic-mitoch PMID:  Reprod Toxicol. 2016 Sep 26 ;66:61-67. Epub 2016 Aug 26. PMID: 27686954 Abstract Title:  In vitro exposure of human spermatozoa to bisphenol A induces pro-oxidative/apoptotic mitochondrial dysfunction. Abstract:  As bisphenol A (BPA) exerts oxidative/pro-apoptotic effects in several cell types, we explored whether the in vitro exposure to BPA could affect human sperm integrity through the induction of pro-oxidative/apoptotic mitochondrial dysfunction. The exposure of motile sperm suspensions to scalar BPA concentrations for 4h produced a decrease in the mitochondrial membrane potential, starting from 300μM. It was associated with an increased mitochondrial generation of superoxide anion, caspase-9 and caspase-3 activation and motility decrement. Vitality decline was observed at BPA≥400μM. Twenty hours exposure to 300μM BPA, but not to lower concentrations, produced a significant loss in spermvitality associated with a complete sperm immobilization. Finally, 300μM BPA also produced a significant DNA oxidative damage, as revealed by the formation of oxidized base adduct 8-hydroxy-2&#039;-deoxyguanosine. In conclusion, BPA affected human sperm integrity by inducing pro-oxidative/apoptotic mitochondrial dysfunction. https://greenmedinfo.com/article/bpa-affected-human-sperm-integrity-inducing-pro-oxidative-and-apoptotic-mitoch#comments Bisphenol Toxicity Spermatogenic Failure Bisphenol A In Vitro Study Mon, 10 Oct 2016 19:16:09 +0000 greenmedinfo 135883 at https://greenmedinfo.com Gardasil Contaminant Confirmed By Independent Lab https://greenmedinfo.com/blog/gardasil-contaminant-confirmed-independent-lab <div class="copyright">This article is copyrighted by GreenMedInfo LLC, 2014<br/><strong><a href="/greenmedinfocom-re-post-guidelines">Visit our Re-post guidelines</a></strong></div><p class="rtecenter"><img alt="Gardasil Contaminant Confirmed By Independent Lab" src="//cdn.greenmedinfo.com/sites/default/files/ckeditor/stebu/images/Gardasil.jpg" style="width: 500px; height: 333px;" /></p> <p>By Norma Erickson</p> <p>In September 2011, <a href="http://sanevax.org/sane-vax-to-fda-recombinant-hpv-dna-found-in-multiple-samples-of-gardasil/" rel="nofollow">SaneVax Inc.</a> informed the FDA that despite all Merck's statements claiming <strong><a href="/anti-therapeutic-action/vaccination-hpv-gardisil">Gardasil</a></strong> contained 'no viral DNA,' Dr. Sin Hang Lee had discovered there were indeed fragments of <a href="/blog/hpv-vaccines-resounding-success-or-future-failure">HPV-11</a>, <a href="/blog/study-reveals-unavoidable-danger-hpv-vaccines">HPV-16</a> and HPV-18 L1 DNA firmly attached to Merck's proprietary aluminum adjuvant in 100% of the samples his laboratory tested.&nbsp;</p><p><a href="https://greenmedinfo.com/blog/gardasil-contaminant-confirmed-independent-lab" target="_blank">read more</a></p> https://greenmedinfo.com/blog/gardasil-contaminant-confirmed-independent-lab#comments Adrenoleukodystrophy Follicular Lymphoma Kidney Diseases Spermatogenic Failure Vaccine-induced Toxicity Human Papillomavirus Virus Vaccination: HPV (Gardasil) Vaccine Information Center Gardasil HPV HPV-11 HPV-16 HPV-18 SaneVax Mon, 12 May 2014 19:06:51 +0000 sanevax 112388 at https://greenmedinfo.com