mitochondria dysfunction https://greenmedinfo.com/category/disease/mitochondria%20dysfunction en Vaccine McCarthyism: Did 2014 Mark the Collapse of the Vaccine Establishment https://greenmedinfo.com/blog/vaccine-mccarthyism-did-2014-mark-collapse-vaccine-establishment <div class="copyright">This article is copyrighted by GreenMedInfo LLC, 2015<br/><strong><a href="/greenmedinfocom-re-post-guidelines">Visit our Re-post guidelines</a></strong></div><p class="rtecenter"><br /> <img alt="Vaccine McCarthyism: Did 2014 Mark the Collapse of the Vaccine Establishment" src="//cdn.greenmedinfo.com/sites/default/files/ckeditor/stebu/images/71b598a2d858d8a2cd0ef33342a555e8e945c6d2725675ee710d8ee507a837ad.jpg" style="width: 600px; height: 385px;" /></p> <p><em><strong>What if vaccines have never been soundly confirmed to be safe and effective? What if the CDC, vaccine manufacturers and advocates knew of these discrepancies and contradictions, yet intentionally ignored them against the public interests?</strong></em></p><p><a href="https://greenmedinfo.com/blog/vaccine-mccarthyism-did-2014-mark-collapse-vaccine-establishment" target="_blank">read more</a></p> https://greenmedinfo.com/blog/vaccine-mccarthyism-did-2014-mark-collapse-vaccine-establishment#comments Autism Depression Guillain-Barre Syndrome H1N1 Measles mitochondria dysfunction Multiple Sclerosis Pertussis Polio Rubella Thimerosal Vaccination: All Vaccination: Hepatitis B Vaccination: Influenza Vaccination: Mumps-Measles-Rubella (MMR) Vaccination: Varicella (Chicken pox) Autism Brian Hooker CDC Chicken Pox Vaccine Depression FDA Guillain-Barre Syndrome H1N1 Health and Human Services Hepatitis B Vaccine Influenza Vaccine Measles mitochondria dysfunction MMR Vaccine Multiple Sclerosis pertussis Polio Rubella Thimerosal Vaccines VAERS William Thompson Wed, 28 Jan 2015 18:40:09 +0000 rgale 116151 at https://greenmedinfo.com Vitamin B12 attenuates acute pancreatitis. https://greenmedinfo.com/article/vitamin-b12-attenuates-acute-pancreatitis PMID:  Oxid Med Cell Longev. 2021 ;2021:7936316. Epub 2021 Dec 9. PMID: 34925701 Abstract Title:  Vitamin BAttenuates Acute Pancreatitis by Suppressing Oxidative Stress and Improving Mitochondria Dysfunction via CBS/SIRT1 Pathway. Abstract:  Acute pancreatitis is an inflammatory disorder of the pancreas associated with substantial morbidity and mortality, which is characterized by a rapid depletion of glutathione (GSH). Cysthionine--synthase (CBS) is a key coenzyme in GSH synthesis, and its deficiency is related to a variety of clinical diseases. However, whether CBS is involved in the pathogenesis of acute pancreatitis remains unclear. First, we found that CBS was downregulated in bothandAP models. The pancreatic damage and acinar cell necrosis related to CBS deficiency were significantly improved by VB 12, which stimulated clearance of reactive oxygen species (ROS) by conserving GSH. Furthermore, EX-527 (a specific inhibitor of SIRT1) exposure counteracted the protective effect of VB 12 by promoting oxidative stress and aggravating mitochondrial damage without influencing CBS, indicating that vitamin Bregulates SIRT1 to improve pancreatical damage by activating CBS. In conclusion, we found that VB 12 protected acute pancreatitis associated with oxidative stress via CBS/SIRT1 pathway. <p><a href="https://greenmedinfo.com/article/vitamin-b12-attenuates-acute-pancreatitis" target="_blank">read more</a></p> https://greenmedinfo.com/article/vitamin-b12-attenuates-acute-pancreatitis#comments mitochondria dysfunction Pancreatitis Vitamin B-12 Antioxidants Pancreato Protective Agents Animal Study In Vitro Study Wed, 22 Dec 2021 01:04:10 +0000 greenmedinfo 250569 at https://greenmedinfo.com