glyphosate-based herbicides (GBH) https://greenmedinfo.com/category/keywords/glyphosate-based%20herbicides%20%28GBH%29 en Explosive New Evidence Confirms Kevin Folta Consulted for Bayer, Despite All his Denials https://greenmedinfo.com/blog/explosive-new-evidence-confirms-kevin-folta-consulted-bayer-despite-all-his-denia <p>&nbsp;</p> <p class="rtecenter"><img alt="" src="//cdn.greenmedinfo.com/sites/default/files/ckeditor/Kate Colter/images/Clifford_Chance_letter_to_Folta_1200x600a.jpg" style="width: 600px; height: 315px;" /></p> <p class="rtecenter"><em><span style="font-size:14px;"><span style="font-family:verdana,geneva,sans-serif;">Science journalist calls Folta a liar, challenges Folta to sue him</span></span></em></p><p><a href="https://greenmedinfo.com/blog/explosive-new-evidence-confirms-kevin-folta-consulted-bayer-despite-all-his-denia" target="_blank">read more</a></p> https://greenmedinfo.com/blog/explosive-new-evidence-confirms-kevin-folta-consulted-bayer-despite-all-his-denia#comments Glyphosate GMOs Glyphosate:Roundup GMOs GMOs Bayer Glyphosate poisoning glyphosate-based herbicides (GBH) GMO Fri, 24 May 2019 19:15:28 +0000 GMWatch 188205 at https://greenmedinfo.com Ultra-low dose of Roundup herbicide non-alcoholic contributes to fatty liver disease in rats following chronic exposure. https://greenmedinfo.com/article/ultra-low-dose-roundup-herbicide-non-alcoholic-contributes-fatty-liver-disease n/a PMID:  Sci Rep. 2017 Jan 9 ;7:39328. Epub 2017 Jan 9. PMID: 28067231 Abstract Title:  Multiomics reveal non-alcoholic fatty liver disease in rats following chronic exposure to an ultra-low dose of Roundup herbicide. Abstract:  The impairment of liver function by low environmentally relevant doses of glyphosate-based herbicides (GBH) is still a debatable and unresolved matter. Previously we have shown that rats administered for 2 years with 0.1 ppb (50 ng/L glyphosate equivalent dilution; 4 ng/kg body weight/day daily intake) of a Roundup GBH formulation showed signs of enhanced liver injury as indicated by anatomorphological, blood/urine biochemical changes and transcriptome profiling. Here we present a multiomic study combining metabolome and proteome liver analyses to obtain further insight into the Roundup-induced pathology. Proteins significantly disturbed (214 out of 1906 detected, q &lt; 0.05) were involved in organonitrogen metabolism and fatty acid β-oxidation. Proteome disturbances reflected peroxisomal proliferation, steatosis and necrosis. The metabolome analysis (55 metabolites altered out of 673 detected, p &lt; 0.05) confirmed lipotoxic conditions and oxidative stress by showing an activation of glutathione and ascorbate free radical scavenger systems. Additionally, we found metabolite alterations associated with hallmarks of hepatotoxicity such as γ-glutamyl dipeptides, acylcarnitines, and proline derivatives. Overall, metabolome and proteome disturbances showed a substantial overlap with biomarkers of non-alcoholic fatty liver disease and its progression to steatohepatosis and thus confirm liver functional dysfunction resulting from chronic ultra-low dose GBH exposure. https://greenmedinfo.com/article/ultra-low-dose-roundup-herbicide-non-alcoholic-contributes-fatty-liver-disease#comments Nonalcoholic fatty liver disease (NAFLD) Glyphosate Hepatotoxic Roundup (herbicide) glyphosate glyphosate-based herbicides (GBH) Nonalcoholic fatty liver disease (NAFLD) Roundup (herbicide) Animal Study Tue, 10 Jan 2017 13:30:43 +0000 greenmedinfo 141761 at https://greenmedinfo.com