Fasting/Caloric Restriction

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91 Diseases Researched for Fasting/Caloric Restriction
NameACCKFocus
Diabetes Mellitus: Type 21169Locked
Obesity1262Locked
Inflammation839Locked
Insulin Resistance832Locked
Aging1323Locked
Cancers: All820Locked
Chemotherapy and Radiation Toxicity220Locked
Hyperinsulinism220Locked
Overweight 220Locked
Rheumatoid Arthritis220Locked
Cardiovascular Diseases617Locked
Adiponectin: Low Levels110Locked
Autism Spectrum Disorders110Locked
Bladder Cancer110Locked
Breast Cancer110Locked
C-Reactive Protein110Locked
Celiac Disease110Locked
Chemotherapy-Induced Nausea110Locked
Chemotherapy-Induced Toxicity: Doxorubicin110Locked
Cortisol: High110Locked
DNA damage110Locked
Diabetes Mellitus: Type 1: Prevention110Locked
Diabetes: Cardiovascular Illness110Locked
Dyslipidemias110Locked
Endothelial Dysfunction110Locked
Female110Locked
Hyperthyroidism110Locked
Metabolic Syndrome X110Locked
Nonalcoholic fatty liver disease (NAFLD)110Locked
Osteoporosis110Locked
Polymyalgia Rheumatica110Locked
Rett Syndrome110Locked
Smoking110Locked
Testosterone: Too High110Locked
Cognitive Decline/Dysfunction36Locked
Oxidative Stress36Locked
High Fat Diet35Locked
Alzheimer's Disease34Locked
Autoimmune Diseases24Locked
Aging: Brain 23Locked
Appendicitis13Locked
Liver Cancer23Locked
Stroke: Ischemic23Locked
Abdominal Obesity (Midsection Fat)12Locked
Acute T cell Leukemias12Locked
Acute lymphoblastic leukemia (ALL)12Locked
Anxiety12Locked
Anxiety Disorders12Locked
Atherosclerosis12Locked
Cardiac Hypertrophy12Locked
Cerebral Hypoperfusion12Locked
Cerebral Ischemia12Locked
Charcot-Marie-Tooth Disease12Locked
Colitis12Locked
Colorectal Cancer12Locked
Dementia12Locked
Diabetes Mellitus: Type 112Locked
Diabetes: Oxidative Stress12Locked
Drug Addiction12Locked
Drug-Induced Toxicity: Bisphosphonates12Locked
Epilepsy12Locked
Epileptic Seizures12Locked
Fructose-Induced Toxicity 12Locked
High Fructose Diet12Locked
Hyperglycemia12Locked
Hypoxia12Locked
Inflammation: Brain12Locked
Intestinal Diseases12Locked
Intestinal Permeability 12Locked
Ischemia12Locked
Liver Steatosis12Locked
Metabolic Diseases12Locked
Multiple Sclerosis12Locked
Multiple Sclerosis: Relapsing-Remitting 12Locked
Muscle Atrophy 12Locked
Myocardial Ischemia12Locked
Neurodegenerative Diseases22Locked
Postmenopausal Disorders: Memory Impairment12Locked
Radiation-Induced Illness: Plutonium 12Locked
Sarcopenia12Locked
Weight Probems: Appetite 12Locked
Cancers11Locked
Chronic Pain11Locked
Fever11Locked
Left Ventricular Dysfunction11Locked
Lipopolysaccharide-Induced Toxicity11Locked
Lung Cancer11Locked
Musculoskeletal Diseases11Locked
Parkinson's Disease11Locked
Polycystic Ovary Syndrome11Locked
Stroke11Locked
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View the Evidence:
110 Abstracts with Fasting/Caloric Restriction Research

[+]

The ketone body, beta-hydroxybutyrate, associated with the low-carb diet and fasting may be responsible for the initial euphoria experienced by those undergoing these dietary modifications.Jan 01, 2007

Pubmed Data : Med Hypotheses. 2007;68(2):268-71. Epub 2006 Oct 2. PMID: 17011713
Article Published Date : Jan 01, 2007
Study Type : Meta Analysis
Additional Links
Therapeutic Actions : Dietary Modification: Low Carbohydrate/Ketogenic, Fasting/Caloric Restriction
[+]

A vegetarian diet has a beneficial effect in patients with rheumatoid arthritis. Sep 01, 1999

Pubmed Data : Am J Clin Nutr. 1999 Sep;70(3 Suppl):594S-600S. PMID: 10479237
Article Published Date : Sep 01, 1999
Study Type : Human Study
Additional Links
Diseases : Rheumatoid Arthritis
Therapeutic Actions : Dietary Modification: Vegetarian, Fasting/Caloric Restriction
[+]

Accumulated data illustrated the hypoglycemic potential of chokeberry juice.Dec 31, 2001

Pubmed Data : Folia Med (Plovdiv). 2002 ;44(3):20-3. PMID: 12580526
Article Published Date : Dec 31, 2001
Study Type : Human Study
Additional Links
Diseases : Diabetes Mellitus: Type 1: Prevention, Diabetes Mellitus: Type 2
Therapeutic Actions : Fasting/Caloric Restriction
Pharmacological Actions : Hypoglycemic Agents
Additional Keywords : Plant Extracts
[+]

Acute high-oleic peanut consumption leads to stronger moderation of postprandial glucose, insulin, and TNF-α concentrationsAug 31, 2014

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Obesity (Silver Spring). 2014 Sep ;22(9):1981-8. Epub 2014 Jun 27. PMID: 24975522
Article Published Date : Aug 31, 2014
Study Type : Human Study
Additional Links
Substances : Peanut
Diseases : Inflammation, Obesity
Therapeutic Actions : Fasting/Caloric Restriction
Pharmacological Actions : Anti-Inflammatory Agents, Hypoglycemic Agents, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

Alternate-day fasting appears to be an effective diet therapy for individuals with NAFLD that can achieve weight loss and improvement of dyslipidaemia.Dec 17, 2019

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : BMC Gastroenterol. 2019 Dec 18 ;19(1):219. Epub 2019 Dec 18. PMID: 31852444
Article Published Date : Dec 17, 2019
Study Type : Human Study
Additional Links
Diseases : Dyslipidemias, Nonalcoholic fatty liver disease (NAFLD)
Therapeutic Actions : Fasting/Caloric Restriction
[+]

Caloric restriction ameliorates defective insulin binding to receptors in obese men. Jan 01, 1975

Pubmed Data : J Clin Invest. 1975 Jan;55(1):166-74. PMID: 1109176
Article Published Date : Jan 01, 1975
Study Type : Human Study
Additional Links
Diseases : Hyperinsulinism, Insulin Resistance
Therapeutic Actions : Dietary Modification: Caloric Restriction , Fasting/Caloric Restriction
[+]

Caloric restriction reduces serum testosterone levels and increases serum sex hormone-binding globulin in humans.Apr 01, 2010

Pubmed Data : Aging Cell. 2010 Apr;9(2):236-42. Epub 2010 Jan 20. PMID: 20096034
Article Published Date : Apr 01, 2010
Study Type : Human Study
Additional Links
Diseases : Testosterone: Too High
Therapeutic Actions : Fasting/Caloric Restriction
[+]

Caloric restriction results in a consistent reduction in circulating levels of growth factors, anabolic hormones, inflammatory cytokines and oxidative stress markers associated with various malignancies.Feb 01, 2010

Pubmed Data : Trends Pharmacol Sci. 2010 Feb;31(2):89-98. Epub 2010 Jan 25. PMID: 20097433
Article Published Date : Feb 01, 2010
Study Type : Human Study
Additional Links
Diseases : Cancers: All
Therapeutic Actions : Fasting/Caloric Restriction
[+]

Calorically restricted diets could be effective in reducing the anxiety and in improving motor behavior in girls with Rett Syndrome.Jun 01, 2009

Pubmed Data : Epilepsy Behav. 2009 Jun;15(2):133-41. Epub 2009 Feb 26. PMID: 19249385
Article Published Date : Jun 01, 2009
Study Type : Human Study
Additional Links
Diseases : Autism Spectrum Disorders, Rett Syndrome
Therapeutic Actions : Dietary Modification: Low Carbohydrate/Ketogenic, Fasting/Caloric Restriction
[+]

Dietary restriction has been studied for a wide range of health benefits in the animal model. Jan 01, 2010

Pubmed Data : J Physiol Anthropol. 2010;29(4):127-32. PMID: 20686325
Article Published Date : Jan 01, 2010
Study Type : Human Study
Additional Links
Therapeutic Actions : Fasting/Caloric Restriction
[+]

Exercise with or without alternate day fasting improves cholesterol metabolism as measured by serum sterol signatures.Jan 03, 2019

Pubmed Data : Metabolism. 2019 Jan 4. Epub 2019 Jan 4. PMID: 30615947
Article Published Date : Jan 03, 2019
Study Type : Human Study
Additional Links
Diseases : Obesity
Therapeutic Actions : Exercise, Fasting/Caloric Restriction
Pharmacological Actions : Anticholesteremic Agents
[+]

Fasting and a one-year vegetarian diet can reduce disease activity in some patients with rheumatoid arthritis.Jan 01, 1995

Pubmed Data : Scand J Rheumatol. 1995;24(2):85-93. PMID: 7747149
Article Published Date : Jan 01, 1995
Study Type : Human Study
Additional Links
Diseases : Rheumatoid Arthritis
Therapeutic Actions : Dietary Modification: Vegetarian, Fasting/Caloric Restriction
Pharmacological Actions : Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

Fasting may confer some protection to host tissues against chemotherapy damage to normal tissues.Dec 31, 2015

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : BMC Cancer. 2016 ;16(1):360. Epub 2016 Jun 10. PMID: 27282289
Article Published Date : Dec 31, 2015
Study Type : Human Study
Additional Links
Diseases : Chemotherapy and Radiation Toxicity, Chemotherapy-Induced Nausea
Therapeutic Actions : Fasting/Caloric Restriction
Pharmacological Actions : Chemoprotective Agents
[+]

Fasting may have therapeutic value in the treatment of polymyalgia rheumatica. Aug 01, 2007

Pubmed Data : Forsch Komplementmed. 2007 Aug;14(4):235-9. Epub 2007 Jul 20. PMID: 17848800
Article Published Date : Aug 01, 2007
Study Type : Human Study
Additional Links
Diseases : Polymyalgia Rheumatica
Therapeutic Actions : Fasting/Caloric Restriction
[+]

Green tea extract decreased fasting insulin concentrations in those with elevated baseline fasting concentrations.Jan 01, 2016

Pubmed Data : J Nutr. 2016 Jan ;146(1):38-45. Epub 2015 Nov 18. PMID: 26581683
Article Published Date : Jan 01, 2016
Study Type : Human Study
Additional Links
Substances : Catechin , Polyphenols, Tea
Diseases : Adiponectin: Low Levels, Obesity
Therapeutic Actions : Fasting/Caloric Restriction
Additional Keywords : Plant Extracts
Problem Substances : Insulin
[+]

High dose magnesium may improve control and/or prevent complications in type 2 diabetic patients. May 01, 1998

Pubmed Data : Diabetes Care. 1998 May;21(5):682-6. PMID: 9589224
Article Published Date : May 01, 1998
Study Type : Human Study
Additional Links
Substances : Magnesium
Diseases : Diabetes: Cardiovascular Illness, Diabetes Mellitus: Type 2
Therapeutic Actions : Fasting/Caloric Restriction
[+]

Intermittent fasting has beneficial effects on health markers in those with type 2 diabetes.Apr 14, 2017

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : World J Diabetes. 2017 Apr 15 ;8(4):154-164. PMID: 28465792
Article Published Date : Apr 14, 2017
Study Type : Human Study
Additional Links
Diseases : Diabetes Mellitus: Type 2
Therapeutic Actions : Fasting/Caloric Restriction
Pharmacological Actions : Hypoglycemic Agents
[+]

Intermittent nutrient and caloric restriction could suppress inflammation in patients suffering with obesity. Dec 31, 2014

Pubmed Data : J Clin Invest. 2015 ;2015. Epub 2015 Nov 3. PMID: 26529255
Article Published Date : Dec 31, 2014
Study Type : Human Study
Additional Links
Diseases : Inflammation, Obesity
Therapeutic Actions : Fasting/Caloric Restriction
Pharmacological Actions : Anti-Inflammatory Agents
[+]

Lemon detox program reduces body fat and insulin resistance through caloric restriction and might have a potential beneficial effect on risk factors for cardiovascular diseaseApr 30, 2015

Pubmed Data : Nutr Res. 2015 May ;35(5):409-20. Epub 2015 Apr 10. PMID: 25912765
Article Published Date : Apr 30, 2015
Study Type : Human Study
Additional Links
Substances : Lemon, Lemon Juice
Diseases : Inflammation, Insulin Resistance, Overweight
Therapeutic Actions : Fasting/Caloric Restriction
Pharmacological Actions : Anti-Inflammatory Agents, Insulin Sensitizers
Additional Keywords : Anti-Obesity Agents, Detoxification, Risk Reduction
[+]

Long-term caloric restriction with adequate protein and micronutrient intake in lean and weight-stable healthy humans is associated with a sustained reduction in serum T(3) concentration.Aug 01, 2006

Pubmed Data : J Clin Endocrinol Metab. 2006 Aug;91(8):3232-5. Epub 2006 May 23. PMID: 16720655
Article Published Date : Aug 01, 2006
Study Type : Human Study
Additional Links
Diseases : Hyperthyroidism
Therapeutic Actions : Fasting/Caloric Restriction
Pharmacological Actions : Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

Monounsaturated fatty acids decrease postprandial hs-CRP.Apr 01, 2013

Pubmed Data : Acta Diabetol. 2013 Apr ;50(2):273-6. Epub 2011 Aug 11. PMID: 21833777
Article Published Date : Apr 01, 2013
Study Type : Human Study
Additional Links
Substances : Monounsaturated fatty acids
Diseases : C-Reactive Protein, Diabetes Mellitus: Type 2, Female
Therapeutic Actions : Fasting/Caloric Restriction
[+]

Regular consumption of chili may attenuate postprandial hyperinsulinemia.Jul 01, 2006

Pubmed Data : Am J Clin Nutr. 2006 Jul;84(1):63-9. PMID: 16825682
Article Published Date : Jul 01, 2006
Study Type : Human Study
Additional Links
Substances : Cayenne, Chili pepper
Diseases : Hyperinsulinism
Therapeutic Actions : Fasting/Caloric Restriction
[+]

Regular peanut consumption within a hypocaloric-diet increased fat oxidation and reduced body fatness in overweigh and obese men.May 31, 2014

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Obesity (Silver Spring). 2014 Jun ;22(6):1422-9. Epub 2014 Mar 27. PMID: 24639419
Article Published Date : May 31, 2014
Study Type : Human Study
Additional Links
Substances : Peanut
Diseases : Obesity, Overweight
Therapeutic Actions : Fasting/Caloric Restriction
Additional Keywords : Anti-Obesity Agents
[+]

Restricting calories increases total output of cortisol.May 01, 2010

Pubmed Data : Psychosom Med. 2010 May;72(4):357-64. Epub 2010 Apr 5. PMID: 20368473
Article Published Date : May 01, 2010
Study Type : Human Study
Additional Links
Diseases : Cortisol: High
Therapeutic Actions : Dietary Modification: Caloric Restriction , Fasting/Caloric Restriction
[+]

Results of this study suggest that prolonged fasting is feasible and might have beneficial clinical effects.Apr 12, 2017

Pubmed Data : Exp Clin Endocrinol Diabetes. 2017 Apr 13. Epub 2017 Apr 13. PMID: 28407662
Article Published Date : Apr 12, 2017
Study Type : Human Study
Additional Links
Diseases : Diabetes Mellitus: Type 2, Metabolic Syndrome X
Therapeutic Actions : Fasting/Caloric Restriction
Pharmacological Actions : Antihypertensive Agents
[+]

Serum leptin level affected in childhood CD is responsive to GFD. Oct 31, 2006

Pubmed Data : J Clin Gastroenterol. 2006 Nov-Dec;40(10):906-9. PMID: 17063109
Article Published Date : Oct 31, 2006
Study Type : Human Study
Additional Links
Diseases : Celiac Disease, Osteoporosis
Therapeutic Actions : Fasting/Caloric Restriction
Pharmacological Actions : Leptin Down-Regulation
Problem Substances : Gluten
[+]

Short term fasting during chemotherapy was well tolerated and reduced hematological toxicity of TAC in HER2-negative BC patients.Oct 04, 2015

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : BMC Cancer. 2015 Oct 5 ;15:652. Epub 2015 Oct 5. PMID: 26438237
Article Published Date : Oct 04, 2015
Study Type : Human Study
Additional Links
Diseases : Breast Cancer, Chemotherapy and Radiation Toxicity, Chemotherapy-Induced Toxicity: Doxorubicin, DNA damage
Therapeutic Actions : Fasting/Caloric Restriction
Pharmacological Actions : Chemotherapeutic
Additional Keywords : Risk Reduction
[+]

There is an increased risk of bladder cancer in smokers with lower serum vitamin D. Nov 01, 2002

Pubmed Data : Biol Trace Elem Res. 2002 Nov;89(2):105-10. PMID: 20978193
Article Published Date : Nov 01, 2002
Study Type : Human Study
Additional Links
Substances : beta-Carotene, Vitamin D
Diseases : Bladder Cancer, Smoking
Therapeutic Actions : Fasting/Caloric Restriction
[+]

These findings suggest that chronic onion extract intake ameliorates postprandial endothelial dysfunctionDec 31, 2012

Pubmed Data : J Am Coll Nutr. 2013 ;32(3):160-4. PMID: 23885989
Article Published Date : Dec 31, 2012
Study Type : Human Study
Additional Links
Substances : Onion, Quercetin
Diseases : Cardiovascular Diseases, Endothelial Dysfunction
Therapeutic Actions : Fasting/Caloric Restriction
Pharmacological Actions : Antioxidants
Additional Keywords : Plant Extracts
[+]

Vitamin D supplementation improves serum concentrations of magnesium and selenium in a gender-dependent manner.Dec 31, 2013

Pubmed Data : Int J Vitam Nutr Res. 2014 ;84(1-2):27-34. PMID: 25835233
Article Published Date : Dec 31, 2013
Study Type : Human Study
Additional Links
Substances : Magnesium, Selenium, Vitamin D
Diseases : Diabetes Mellitus: Type 2
Therapeutic Actions : Fasting/Caloric Restriction
Additional Keywords : Parathyroid Hormone, Supplementation
[+]

The metabolic effects of fasting on human and mouse blood in vivo.Jan 05, 2017

Pubmed Data : Autophagy. 2017 Jan 6:0. Epub 2017 Jan 6. PMID: 28059587
Article Published Date : Jan 05, 2017
Study Type : Animal Study, Human In Vitro
Additional Links
Therapeutic Actions : Fasting/Caloric Restriction
[+]

Case Study: a medically supervised water-only fast followed by a plant-based, low-fat, low-sodium diet acheived remission of suspected uncomplicated subacute appendicitis.Mar 01, 2011

Pubmed Data : J Altern Complement Med. 2011 Mar;17(3):275-7. Epub 2011 Mar 9. PMID: 21417813
Article Published Date : Mar 01, 2011
Study Type : Human: Case Report
Additional Links
Diseases : Appendicitis
Therapeutic Actions : Dietary Modification: Vegetarian, Doing Nothing, Expectant Management, Fasting/Caloric Restriction
[+]

A diet mimicking fasting promotes regeneration and reduces autoimmunity and multiple sclerosis symptoms.Jun 06, 2016

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Cell Rep. 2016 Jun 7 ;15(10):2136-46. Epub 2016 May 26. PMID: 27239035
Article Published Date : Jun 06, 2016
Study Type : Animal Study
Additional Links
Diseases : Autoimmune Diseases, Multiple Sclerosis: Relapsing-Remitting
Therapeutic Actions : Dietary Modification: Low Carbohydrate/Ketogenic, Fasting/Caloric Restriction
Additional Keywords : Dietary Modification
[+]

A human fasting mimicking diet decreased risk factors for aging, diabetes, cardiovascular disease, and cancer without major adverse effects.Jul 06, 2015

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Cell Metab. 2015 Jul 7 ;22(1):86-99. Epub 2015 Jun 18. PMID: 26094889
Article Published Date : Jul 06, 2015
Study Type : Animal Study, In Vitro Study
Additional Links
Diseases : Aging, Cancers: All, Cardiovascular Diseases, Diabetes Mellitus: Type 2
Therapeutic Actions : Fasting/Caloric Restriction
Additional Keywords : Dietary Modification, Risk Reduction
[+]

A ketogenic diet has antiepileptogenic effects.Mar 01, 2009

Pubmed Data : Neurochem Int. 2009 Mar-Apr;54(3-4):199-204. Epub 2008 Nov 30. PMID: 19100800
Article Published Date : Mar 01, 2009
Study Type : Animal Study
Additional Links
Diseases : Epilepsy, Epileptic Seizures
Therapeutic Actions : Fasting/Caloric Restriction
[+]

Anti-diabetic effect mediated by Ramulus mori polysaccharides.Mar 05, 2015

Pubmed Data : Carbohydr Polym. 2015 Mar 6 ;117:63-69. Epub 2014 Sep 28. PMID: 25498609
Article Published Date : Mar 05, 2015
Study Type : Animal Study
Additional Links
Substances : Mulberry
Diseases : Hyperglycemia
Therapeutic Actions : Fasting/Caloric Restriction
Pharmacological Actions : Anti-Apoptotic, Hypoglycemic Agents, Pancreato Protective Agents
Additional Keywords : Polysaccharides
[+]

Caloric restriction and alternative-day fasting may increase lifespan. Jan 01, 2008

Pubmed Data : PLoS One. 2008;3(9):e3211. Epub 2008 Sep 15. PMID: 18791640
Article Published Date : Jan 01, 2008
Study Type : Animal Study
Additional Links
Diseases : Aging
Therapeutic Actions : Fasting/Caloric Restriction
[+]

Caloric restriction and resveratrol promote longevity.Jan 01, 2010

Pubmed Data : Cell Death Dis. 2010 Jan;1(1):e10. PMID: 21364612
Article Published Date : Jan 01, 2010
Study Type : Animal Study
Additional Links
Substances : Resveratrol
Diseases : Aging
Therapeutic Actions : Fasting/Caloric Restriction
Pharmacological Actions : Autophagy Up-regulation, SIRT1 Activator
[+]

Caloric restriction appears to ameliorate oxidative stress and aging in connection with the hydrogen sulfide signaling system.May 26, 2010

Pubmed Data : Age (Dordr). 2010 May 26. Epub 2010 May 26. PMID: 20502969
Article Published Date : May 26, 2010
Study Type : Animal Study
Additional Links
Diseases : Aging
Therapeutic Actions : Fasting/Caloric Restriction
[+]

Caloric restriction delays disease onset and mortality in rhesus monkeys.Sep 15, 2009

Pubmed Data : Theriogenology. 2009 Sep 15;72(5):624-35. Epub 2009 Jul 14. PMID: 19590001
Article Published Date : Sep 15, 2009
Study Type : Animal Study
Additional Links
Diseases : Aging, Cardiovascular Diseases
Therapeutic Actions : Fasting/Caloric Restriction
[+]

Caloric restriction enhances cell adaptation to hypoxia.Apr 01, 2010

Pubmed Data : J Clin Invest. 2010 Apr 1;120(4):1043-55. Epub 2010 Mar 24. PMID: 20335657
Article Published Date : Apr 01, 2010
Study Type : Animal Study
Additional Links
Diseases : Aging, Hypoxia
Therapeutic Actions : Dietary Modification: Caloric Restriction , Fasting/Caloric Restriction
[+]

Caloric restriction extend lifespan in animals with the decreased frequency of age-related diseases.Dec 01, 2004

Pubmed Data : J Inorg Biochem. 2004 Dec;98(12):2063-70. PMID: 19591287
Article Published Date : Dec 01, 2004
Study Type : Animal Study
Additional Links
Diseases : Aging
Therapeutic Actions : Fasting/Caloric Restriction
[+]

Caloric restriction increases the expression of genes involved in energy metabolism and it down-regulates the expression of more than 50 pro-inflammatory genes.Jan 01, 2009

Pubmed Data : Toxicol Pathol. 2009;37(1):47-51. Epub 2008 Dec 15. PMID: 19075044
Article Published Date : Jan 01, 2009
Study Type : Animal Study
Additional Links
Diseases : Aging, Inflammation, Inflammation: Brain, Sarcopenia
Therapeutic Actions : Fasting/Caloric Restriction
[+]

Caloric restriction may have an antineoplastic (anti-cancer) effect through the induction of genes responsible for protection against oxidative and genotoxic stress.Jun 01, 2010

Pubmed Data : Aging Cell. 2010 Jun;9(3):372-82. Epub 2010 Mar 6. PMID: 20222901
Article Published Date : Jun 01, 2010
Study Type : Animal Study
Additional Links
Diseases : Cancers: All, Oxidative Stress
Therapeutic Actions : Fasting/Caloric Restriction
Pharmacological Actions : Antineoplastic Agents, Antioxidants
[+]

Caloric restriction may up-regulate the autophagy pathway for cancer chemoprevention. Apr 01, 2010

Pubmed Data : Curr Opin Cell Biol. 2010 Apr;22(2):218-25. Epub 2010 Jan 22. PMID: 20096553
Article Published Date : Apr 01, 2010
Study Type : Animal Study
Additional Links
Diseases : Cancers: All
Therapeutic Actions : Fasting/Caloric Restriction
Pharmacological Actions : Autophagy Up-regulation
[+]

Calorie restriction led to improvements in overall health and function in rhesus monkeys. Sep 12, 2012

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Nature. 2012 Sep 13 ;489(7415):318-21. PMID: 22932268
Article Published Date : Sep 12, 2012
Study Type : Animal Study
Additional Links
Therapeutic Actions : Fasting/Caloric Restriction
[+]

Camel milk inhibits the diabetes-induced elevation in incretin hormones, TNF-α and TGF-β1 levels.May 31, 2014

Pubmed Data : Horm Metab Res. 2014 Jun ;46(6):404-11. Epub 2014 Mar 13. PMID: 24627103
Article Published Date : May 31, 2014
Study Type : Animal Study
Additional Links
Substances : Camel Milk
Diseases : Atherosclerosis, Diabetes Mellitus: Type 2, Insulin Resistance
Therapeutic Actions : Fasting/Caloric Restriction
Pharmacological Actions : Anti-Inflammatory Agents, Hypoglycemic Agents, Tumor Necrosis Factor (TNF) Alpha Inhibitor
Problem Substances : Insulin
[+]

Chronic treatment of pterostilbene remarkably reduced the pathological changes observed in liver and kidney of diabetic rats. Nov 01, 2006

Pubmed Data : J Pharm Pharmacol. 2006 Nov;58(11):1483-90. PMID: 17132211
Article Published Date : Nov 01, 2006
Study Type : Animal Study
Additional Links
Substances : Pterostilbene
Diseases : Diabetes: Oxidative Stress
Therapeutic Actions : Fasting/Caloric Restriction
Pharmacological Actions : Antioxidants
Additional Keywords : Stilbenes
[+]

Cinnamaldehyde co-administration prevented HFD-induced body weight gain, and decreased fasting-induced hyperphagia.Feb 29, 2016

Pubmed Data : Biofactors. 2016 Mar-Apr;42(2):201-11. Epub 2016 Feb 19. PMID: 26893251
Article Published Date : Feb 29, 2016
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Cinnamaldehyde
Diseases : High Fat Diet, Inflammation, Obesity
Therapeutic Actions : Fasting/Caloric Restriction
Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-1 beta downregulation
Additional Keywords : Anti-Obesity Agents
[+]

Dietary methionine restriction improves colon tight junction barrier runction. Aug 25, 2010

Pubmed Data : Am J Physiol Cell Physiol. 2010 Aug 25. Epub 2010 Aug 25. PMID: 20739626
Article Published Date : Aug 25, 2010
Study Type : Animal Study
Additional Links
Diseases : Intestinal Permeability
Therapeutic Actions : Fasting/Caloric Restriction
[+]

Dietary restriction is associated with improved skeletal muscle insulin sensitivity in rats.Jul 01, 2010

Pubmed Data : Br J Nutr. 2010 Jul;104(1):76-82. Epub 2010 Feb 24. PMID: 20178670
Article Published Date : Jul 01, 2010
Study Type : Animal Study
Additional Links
Diseases : Diabetes Mellitus: Type 2, Inflammation, Insulin Resistance
Therapeutic Actions : Fasting/Caloric Restriction
[+]

Docosahexaenoic acid-supplementation prior to fasting prevents muscle atrophy in mice.Feb 14, 2016

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : J Cachexia Sarcopenia Muscle. 2016 Feb 15. Epub 2016 Feb 15. PMID: 27239420
Article Published Date : Feb 14, 2016
Study Type : Animal Study
Additional Links
Substances : DHA (Docosahexaenoic Acid)
Diseases : Muscle Atrophy
Therapeutic Actions : Fasting/Caloric Restriction
[+]

Fasting activates fatty acid oxidation to enhance intestinal stem cell function during homeostasis and aging.May 02, 2018

Pubmed Data : Cell Stem Cell. 2018 May 3 ;22(5):769-778.e4. PMID: 29727683
Article Published Date : May 02, 2018
Study Type : Animal Study
Additional Links
Diseases : Aging
Therapeutic Actions : Fasting/Caloric Restriction
[+]

Fasting inhibits colorectal cancer growth by reducing M2 polarization of tumor-associated macrophages.Sep 25, 2017

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Oncotarget. 2017 Sep 26 ;8(43):74649-74660. Epub 2017 Aug 16. PMID: 29088814
Article Published Date : Sep 25, 2017
Study Type : Animal Study, In Vitro Study
Additional Links
Diseases : Colorectal Cancer
Therapeutic Actions : Fasting/Caloric Restriction
Pharmacological Actions : Antiproliferative
Additional Keywords : Tumor Microenvironment
[+]

Fasting selectively blocks development of acute lymphoblastic leukemia.Dec 31, 2016

Pubmed Data : Nat Med. 2017 Jan ;23(1):79-90. Epub 2016 Dec 12. PMID: 27941793
Article Published Date : Dec 31, 2016
Study Type : Animal Study
Additional Links
Diseases : Acute lymphoblastic leukemia (ALL), Acute T cell Leukemias
Therapeutic Actions : Fasting/Caloric Restriction
Pharmacological Actions : Antiproliferative , Chemopreventive
Additional Keywords : Acute lymphoblastic leukemia (ALL), Acute T cell Leukemias, Antiproliferative, Chemopreventive, Fasting/Caloric Restriction, Gene Exprsession Regulation, Selective Antiproliferation
[+]

Fasting-induced liver GADD45β restrains hepatic fatty acid uptake and improves metabolic health.Dec 31, 2015

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : EMBO Mol Med. 2016 ;8(6):654-69. Epub 2016 Jun 1. PMID: 27137487
Article Published Date : Dec 31, 2015
Study Type : Animal Study
Additional Links
Diseases : Metabolic Diseases, Obesity
Therapeutic Actions : Fasting/Caloric Restriction
Pharmacological Actions : Hepatoprotective
[+]

Fibroblast growth factor-21 could potentially be used as a hormone therapy to extend lifespan in mammals.Dec 31, 2011

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Elife. 2012 ;1:e00065. Epub 2012 Oct 15. PMID: 23066506
Article Published Date : Dec 31, 2011
Study Type : Transgenic Animal Study
Additional Links
Diseases : Insulin Resistance
Therapeutic Actions : Fasting/Caloric Restriction
Pharmacological Actions : Fibroblast growth factor 21 upregulation
[+]

Food restriction may alter neurological function associated with susceptibility to addictive behavior. Jul 25, 2011

Pubmed Data : Physiol Behav. 2011 Jul 25 ;104(1):162-7. Epub 2011 Apr 28. PMID: 21530562
Article Published Date : Jul 25, 2011
Study Type : Animal Study
Additional Links
Diseases : Drug Addiction
Therapeutic Actions : Dietary Modification: Caloric Restriction , Fasting/Caloric Restriction
[+]

Fourteen weeks of treatment with fermented oat and barley fiber increased fasting levels of glucagon-like peptide-1 and peptide-YY.Dec 01, 2007

Pubmed Data : J Med Food. 2007 Dec;10(4):720-4. PMID: 18158848
Article Published Date : Dec 01, 2007
Study Type : Animal Study
Additional Links
Substances : Barley, Fermented Foods and Beverages, Fiber, Oat Bran
Diseases : Weight Probems: Appetite
Therapeutic Actions : Fasting/Caloric Restriction
Pharmacological Actions : Glucagon Like peptide 1 (GLP-1) Up-regulation, Peptide YY (PYY) Up-Regulation
[+]

Green tea prevents and reverses fasting-induced intestinal mucosal damage. Jun 01, 2003

Pubmed Data : Nutrition. 2003 Jun;19(6):536-40. PMID: 12781855
Article Published Date : Jun 01, 2003
Study Type : Animal Study
Additional Links
Substances : Flavonoids, Polyphenols, Vitamin E
Diseases : Intestinal Diseases
Therapeutic Actions : Fasting/Caloric Restriction
Pharmacological Actions : Antioxidants
[+]

Holy basil (O. sanctum) prevents insulin resistance induced through a fructose-fed diet in rats. Jan 01, 2008

Pubmed Data : Horm Metab Res. 2008 Jan;40(1):44-9. Epub 2007 Dec 18. PMID: 18085503
Article Published Date : Jan 01, 2008
Study Type : Animal Study
Additional Links
Substances : Holy Basil
Diseases : Fructose-Induced Toxicity , Insulin Resistance
Therapeutic Actions : Fasting/Caloric Restriction
Additional Keywords : Plant Extracts
[+]

Intermittent fasting alleviates the increase of lipoprotein lipase expression in brain of a mouse model of Alzheimer's disease.Dec 31, 2017

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Front Cell Neurosci. 2018 ;12:1. Epub 2018 Jan 17. PMID: 29386999
Article Published Date : Dec 31, 2017
Study Type : Animal Study
Additional Links
Diseases : Alzheimer's Disease
Therapeutic Actions : Fasting/Caloric Restriction
Pharmacological Actions : Neuroprotective Agents
Additional Keywords : Alzheimer's disease, Fasting/Caloric Restriction, Neuroprotective Agents
[+]

Intermittent fasting alleviates the neuropathic phenotype in a mouse model of Charcot-Marie-Tooth disease.May 01, 2006

Pubmed Data : Ann Dermatol Venereol. 2006 May;133(5 Pt 1):425-8. PMID: 19320048
Article Published Date : May 01, 2006
Study Type : Animal Study
Additional Links
Diseases : Charcot-Marie-Tooth Disease
Therapeutic Actions : Fasting/Caloric Restriction
Pharmacological Actions : Antiproliferative
[+]

Intermittent fasting attenuates inflammasome activity in ischemic stroke.Jun 30, 2014

Pubmed Data : Exp Neurol. 2014 Jul ;257:114-9. Epub 2014 May 5. PMID: 24805069
Article Published Date : Jun 30, 2014
Study Type : Animal Study
Additional Links
Diseases : Stroke: Ischemic
Therapeutic Actions : Fasting/Caloric Restriction
Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-18 down-regulation, Interleukin-1 beta downregulation
[+]

Intermittent fasting benefits on alpha- and beta-cell arrangement in diet-induced obese mice pancreatic islet.Nov 25, 2019

Pubmed Data : J Diabetes Complications. 2019 Nov 26:107497. Epub 2019 Nov 26. PMID: 31866258
Article Published Date : Nov 25, 2019
Study Type : Animal Study
Additional Links
Diseases : Diabetes Mellitus: Type 2, Obesity
Therapeutic Actions : Fasting/Caloric Restriction
Pharmacological Actions : Anti-Apoptotic, Anti-Inflammatory Agents, Pancreato Protective Agents
[+]

Intermittent fasting combined with supplementation with Ayurvedic herbs reduces anxiety in middle aged female rats.May 05, 2017

Pubmed Data : Biogerontology. 2017 May 6. Epub 2017 May 6. PMID: 28478492
Article Published Date : May 05, 2017
Study Type : Animal Study
Additional Links
Substances : Ashwagandha, Guduchi
Diseases : Anxiety
Therapeutic Actions : Fasting/Caloric Restriction
Pharmacological Actions : Anti-Anxiety Agents, Interleukin-1 beta downregulation, Interleukin-6 Downregulation, NF-kappaB Inhibitor, Tumor Necrosis Factor (TNF) Alpha Inhibitor
Additional Keywords : Ayurveda
[+]

Intermittent fasting confers protection in CNS autoimmunity by altering the gut microbiota.Jun 04, 2018

Pubmed Data : Cell Metab. 2018 Jun 5 ;27(6):1222-1235.e6. PMID: 29874567
Article Published Date : Jun 04, 2018
Study Type : Animal Study
Additional Links
Diseases : Autoimmune Diseases, Multiple Sclerosis
Therapeutic Actions : Fasting/Caloric Restriction
Pharmacological Actions : Gastrointestinal Agents, Immunomodulatory
[+]

Intermittent fasting increases the expressions of superoxide dismutase and catalase in the adult gerbil dentate gyrus.Jan 03, 2019

Pubmed Data : Mol Med Rep. 2019 Jan 4. Epub 2019 Jan 4. PMID: 30628688
Article Published Date : Jan 03, 2019
Study Type : Animal Study
Additional Links
Diseases : Oxidative Stress
Therapeutic Actions : Fasting/Caloric Restriction
Pharmacological Actions : Antioxidants, Catalase Up-Regulation, Superoxide Dismutase Up-regulation
[+]

Intermittent fasting is neuroprotective in focal cerebral ischemia.Oct 31, 2016

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Exp Ther Med. 2016 Nov ;12(5):3021-3028. Epub 2016 Oct 31. PMID: 27882110
Article Published Date : Oct 31, 2016
Study Type : Animal Study
Additional Links
Diseases : Cerebral Ischemia
Therapeutic Actions : Fasting/Caloric Restriction
Pharmacological Actions : Anti-Apoptotic, Neuroprotective Agents
[+]

Intermittent fasting may prevent some of the metabolic pathologies associated with menopause and protect against age-related memory decline.Jan 31, 2018

Pubmed Data : Exp Biol Med (Maywood). 2018 Feb ;243(4):334-343. Epub 2018 Jan 7. PMID: 29307281
Article Published Date : Jan 31, 2018
Study Type : Animal Study
Additional Links
Diseases : Aging: Brain , Cognitive Decline/Dysfunction, Postmenopausal Disorders: Memory Impairment
Therapeutic Actions : Fasting/Caloric Restriction
Pharmacological Actions : Neuroprotective Agents
Additional Keywords : Aging: Brain, Cognitive Decline/Dysfunction, Fasting/Caloric Restriction, Neuroprotective Agents
[+]

Intermittent fasting preserves beta-cell mass in obesity-induced diabetes.Aug 29, 2017

Pubmed Data : Autophagy. 2017 Aug 30:0. Epub 2017 Aug 30. PMID: 28853981
Article Published Date : Aug 29, 2017
Study Type : Animal Study
Additional Links
Diseases : Hyperglycemia, Insulin Resistance, Obesity
Therapeutic Actions : Fasting/Caloric Restriction
Pharmacological Actions : Pancreato Protective Agents
[+]

Intermittent fasting pretreatment prevents cognitive impairment in a rat model of chronic cerebral hypoperfusion.May 16, 2017

Pubmed Data : J Nutr. 2017 May 17. Epub 2017 May 17. PMID: 28515159
Article Published Date : May 16, 2017
Study Type : Animal Study
Additional Links
Diseases : Cerebral Hypoperfusion, Cognitive Decline/Dysfunction, Dementia
Therapeutic Actions : Fasting/Caloric Restriction
Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants, Neuroprotective Agents
[+]

Intermittent fasting promotes white adipose browning and decreases obesity by shaping the gut microbiota.Oct 02, 2017

Pubmed Data : Cell Metab. 2017 Oct 3 ;26(4):672-685.e4. Epub 2017 Sep 14. PMID: 28918936
Article Published Date : Oct 02, 2017
Study Type : Animal Study
Additional Links
Diseases : Obesity
Therapeutic Actions : Fasting/Caloric Restriction
Additional Keywords : Anti-Obesity Agents, Microbiota
[+]

Intermittent fasting prompted recovery from dextran sulfate sodium-induced colitis in mice.Aug 31, 2017

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : J Clin Biochem Nutr. 2017 Sep ;61(2):100-107. Epub 2017 Jul 28. PMID: 28955126
Article Published Date : Aug 31, 2017
Study Type : Animal Study, In Vitro Study
Additional Links
Diseases : Colitis
Therapeutic Actions : Fasting/Caloric Restriction
Pharmacological Actions : Anti-Inflammatory Agents
[+]

Long-term intermittent feeding, but not caloric restriction, leads to redox imbalance, insulin receptor nitration, and glucose intolerance.Jul 21, 2011

Pubmed Data : Free Radic Biol Med. 2011 Jul 21. Epub 2011 Jul 21. PMID: 21816219
Article Published Date : Jul 21, 2011
Study Type : Animal Study
Additional Links
Diseases : Abdominal Obesity (Midsection Fat), Insulin Resistance
Therapeutic Actions : Dietary Modification: Caloric Restriction , Fasting/Caloric Restriction
[+]

Melatonin protects against bisphosphanate drug-induced gastric damage.Aug 01, 2005

Pubmed Data : Dig Dis Sci. 2005 Aug;50(8):1506-12. PMID: 16110843
Article Published Date : Aug 01, 2005
Study Type : Animal Study
Additional Links
Substances : Melatonin
Diseases : Drug-Induced Toxicity: Bisphosphonates
Therapeutic Actions : Fasting/Caloric Restriction
Pharmacological Actions : Anti-Ulcer Agents, Antioxidants
[+]

Modest calorie restriction improves cardiac remodeling and diastolic dysfunction in rats. Oct 01, 2006

Pubmed Data : J Mol Cell Cardiol. 2006 Oct;41(4):661-8. Epub 2006 Aug 23. PMID: 16934290
Article Published Date : Oct 01, 2006
Study Type : Animal Study
Additional Links
Diseases : Cardiac Hypertrophy
Therapeutic Actions : Dietary Modification: Caloric Restriction , Fasting/Caloric Restriction
[+]

Polyphenols potentiate dietary restriction-induced lifespan extension.Jan 11, 2012

Pubmed Data : Biochim Biophys Acta. 2012 Jan 11 ;1822(4):522-526. Epub 2012 Jan 11. PMID: 22265987
Article Published Date : Jan 11, 2012
Study Type : Animal Study
Additional Links
Substances : Blueberry, Green Tea, Polyphenols, Pomegranate
Diseases : Aging
Therapeutic Actions : Fasting/Caloric Restriction
Pharmacological Actions : Anti-Inflammatory Agents
[+]

Preoperative dietary restriction reduces hepatic tumor load in a mouse model. Sep 15, 2010

Pubmed Data : J Surg Oncol. 2010 Sep 15;102(4):348-53. PMID: 20672315
Article Published Date : Sep 15, 2010
Study Type : Animal Study
Additional Links
Diseases : Liver Cancer
Therapeutic Actions : Fasting/Caloric Restriction
[+]

Resveratrol and caloric restruction enhance cognitive performance. Jan 01, 2011

Pubmed Data : PLoS One. 2011;6(1):e16581. Epub 2011 Jan 31. PMID: 21304942
Article Published Date : Jan 01, 2011
Study Type : Animal Study
Additional Links
Substances : Resveratrol
Diseases : Cognitive Decline/Dysfunction
Therapeutic Actions : Fasting/Caloric Restriction
[+]

Resveratrol has an ameliorative effect on on proinflammatory cytokines, hyperglycemia mediated oxidative stress, and pancreatic beta-cell dysfunction in diabetic rats. Aug 01, 2010

Pubmed Data : J Cell Physiol. 2010 Aug;224(2):423-32. PMID: 20333650
Article Published Date : Aug 01, 2010
Study Type : Animal Study
Additional Links
Substances : Resveratrol
Diseases : Diabetes Mellitus: Type 1, Oxidative Stress
Therapeutic Actions : Fasting/Caloric Restriction
Pharmacological Actions : Antioxidants
Additional Keywords : Beta Cell Protection, Stilbenes
[+]

Short-term dietary restriction ameliorates brain injury after cardiac arrest by modulation of mitochondrial biogenesis and energy metabolism.Dec 31, 2020

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Ann Transl Med. 2021 Jan ;9(1):8. PMID: 33553301
Article Published Date : Dec 31, 2020
Study Type : Animal Study
Additional Links
Diseases : Myocardial Ischemia
Therapeutic Actions : Fasting/Caloric Restriction
Pharmacological Actions : Cardioprotective
[+]

Short-term dietary restriction and fasting precondition against ischemia reperfusion injury in mice.Feb 01, 2010

Pubmed Data : Aging Cell. 2010 Feb;9(1):40-53. Epub 2009 Oct 30. PMID: 19878145
Article Published Date : Feb 01, 2010
Study Type : Animal Study
Additional Links
Diseases : Ischemia
Therapeutic Actions : Dietary Modification: Caloric Restriction , Fasting/Caloric Restriction
[+]

Short-term fasting may thus prove to be a useful for reducing peripheral inflammatory states associated with visceral obesity and chronic stress.Dec 31, 2015

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Mediators Inflamm. 2016 ;2016:1698071. Epub 2016 Dec 18. PMID: 28077915
Article Published Date : Dec 31, 2015
Study Type : Animal Study
Additional Links
Diseases : Inflammation
Therapeutic Actions : Fasting/Caloric Restriction
Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-1 beta downregulation, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

There is a 10-100 fold increase in plutonium absorption in young and fasted animals. Jul 01, 1986

Pubmed Data : Radiat Res. 1986 Jul;107(1):73-82. PMID: 3737878
Article Published Date : Jul 01, 1986
Study Type : Animal Study
Additional Links
Diseases : Radiation-Induced Illness: Plutonium
Therapeutic Actions : Fasting/Caloric Restriction
Additional Keywords : Infant Body Burden
[+]

There were beneficial effects of Intermittent fasting even with the continuity of the obesogenic diet and proinflammatory diet in mice.Mar 27, 2019

Pubmed Data : Nutrition. 2019 Mar 28 ;65:103-112. Epub 2019 Mar 28. PMID: 31079017
Article Published Date : Mar 27, 2019
Study Type : Animal Study
Additional Links
Diseases : High Fat Diet, High Fructose Diet, Liver Steatosis
Therapeutic Actions : Fasting/Caloric Restriction
Pharmacological Actions : Anti-Inflammatory Agents
[+]

These results indicate that fasting decrease anxiety-like behaviour and improves memory.May 31, 2017

Pubmed Data : Metabolism. 2017 Jun ;71:70-82. Epub 2017 Mar 9. PMID: 28521881
Article Published Date : May 31, 2017
Study Type : Animal Study
Additional Links
Diseases : Anxiety Disorders
Therapeutic Actions : Fasting/Caloric Restriction
Pharmacological Actions : Anti-Anxiety Agents
Additional Keywords : Anti-Anxiety Agents, Anxiety Disorders, Fasting/Caloric Restriction
[+]

Treatment of mice with ALA enhanced fasting-induced up-regulation of CREBH and FGF21 in the liver and inhibited feeding-induced suppression of their expression.Dec 11, 2014

Pubmed Data : Biochem Biophys Res Commun. 2014 Dec 12 ;455(3-4):212-7. Epub 2014 Nov 5. PMID: 25449271
Article Published Date : Dec 11, 2014
Study Type : Animal Study
Additional Links
Substances : Alpha-Lipoic Acid
Therapeutic Actions : Fasting/Caloric Restriction
Pharmacological Actions : Antioxidants, Fibroblast growth factor 21 upregulation
[+]

A comparative review of established diets for prevention of cardiovascular disease and newer dietary strategies.Mar 18, 2020

Pubmed Data : Curr Probl Cardiol. 2020 Mar 19:100582. Epub 2020 Mar 19. PMID: 32389436
Article Published Date : Mar 18, 2020
Study Type : Review
Additional Links
Diseases : Cardiovascular Diseases
Therapeutic Actions : Dietary Modification: Low Carbohydrate/Ketogenic, Fasting/Caloric Restriction
Pharmacological Actions : Cardioprotective
Additional Keywords : Risk Reduction
[+]

A review of the impact of intermittent fasting on health and disease processes.Oct 30, 2016

Pubmed Data : Ageing Res Rev. 2016 Oct 31. Epub 2016 Oct 31. PMID: 27810402
Article Published Date : Oct 30, 2016
Study Type : Review
Additional Links
Diseases : Alzheimer's Disease, Cancers: All, Cardiovascular Diseases, Diabetes Mellitus: Type 2, Parkinson's Disease, Stroke
Therapeutic Actions : Fasting/Caloric Restriction
Additional Keywords : Alzheimer's disease, Cancers: All, Cardiovascular Diseases, Diabetes mellitus: Type 2, Intermittent Fasting, Parkinson's disease, stroke
[+]

A review of the positive effects of intermittent fasting in ischemic stroke.Feb 28, 2017

Pubmed Data : Exp Gerontol. 2017 Mar ;89:93-102. Epub 2017 Jan 20. PMID: 28115234
Article Published Date : Feb 28, 2017
Study Type : Review
Additional Links
Diseases : Stroke: Ischemic
Therapeutic Actions : Fasting/Caloric Restriction
Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants
[+]

Caloric restriction and fasting are generally beneficial to adult stem cell function, while high fat diets impair stem cell function.Feb 28, 2017

Pubmed Data : Curr Stem Cell Rep. 2017 Mar ;3(1):1-8. Epub 2017 Feb 8. PMID: 28966904
Article Published Date : Feb 28, 2017
Study Type : Review
Additional Links
Diseases : High Fat Diet
Therapeutic Actions : Fasting/Caloric Restriction
Additional Keywords : Adult Stem Cells
[+]

Caloric restriction attenuates age-associated impairment seen in left ventricular diastolic function and may retard cardiac senescence by attenuating oxidative damage in the aged heart. Apr 01, 2011

Pubmed Data : Geriatr Gerontol Int. 2011 Apr;11(2):143-56. Epub 2011 Jan 4. PMID: 21199236
Article Published Date : Apr 01, 2011
Study Type : Review
Additional Links
Diseases : Aging, Cardiovascular Diseases, Left Ventricular Dysfunction
Therapeutic Actions : Fasting/Caloric Restriction
Pharmacological Actions : Cardioprotective
[+]

Caloric restriction down-regulates inflammation; the chronic inflammation associated with obesity may be caused by energy accumulation.Jun 01, 2010

Pubmed Data : Aging (Albany NY). 2010 Jun;2(6):361-8. PMID: 20606248
Article Published Date : Jun 01, 2010
Study Type : Review
Additional Links
Diseases : Inflammation, Obesity
Therapeutic Actions : Fasting/Caloric Restriction
Additional Keywords : Diseases that are Linked
[+]

Caloric restriction mimetics enhance anticancer immunosurveillance.Jul 10, 2016

Pubmed Data : Cancer Cell. 2016 Jul 11 ;30(1):147-60. PMID: 27411589
Article Published Date : Jul 10, 2016
Study Type : In Vitro Study
Additional Links
Diseases : Lung Cancer
Therapeutic Actions : Fasting/Caloric Restriction
Pharmacological Actions : Chemotherapeutic
[+]

Chemo-sensitization resulting from fasting may in fact be an effect of enhanced immune surveillance.Dec 31, 2015

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Front Oncol. 2016 ;6:242. Epub 2016 Nov 14. PMID: 27896219
Article Published Date : Dec 31, 2015
Study Type : Review
Additional Links
Diseases : Cancers: All
Therapeutic Actions : Fasting/Caloric Restriction
Pharmacological Actions : Chemosensitizer
Additional Keywords : Cancer, cancer cure, Chemosensitizer, Chemotherapy, Fasting
[+]

Dietary restriction may have neuroprotective effects in the aging brain.Dec 15, 2000

Pubmed Data : Brain Res. 2000 Dec 15;886(1-2):47-53. PMID: 11119686
Article Published Date : Dec 15, 2000
Study Type : Review
Additional Links
Diseases : Aging, Aging: Brain , Neurodegenerative Diseases
Therapeutic Actions : Fasting/Caloric Restriction
Pharmacological Actions : Antiproliferative , Neuroprotective Agents
[+]

Fasting can be prescribed as a safe medical intervention as well as a lifestyle regimen which can improve women’s health in many folds.Mar 31, 2016

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : J Midlife Health. 2016 Apr-Jun;7(2):61-4. PMID: 27499591
Article Published Date : Mar 31, 2016
Study Type : Review
Additional Links
Diseases : Cancers, Musculoskeletal Diseases
Therapeutic Actions : Fasting/Caloric Restriction
Additional Keywords : Risk Reduction
[+]

Fasting during fevers due to infection may significantly reduce the risk of developing autoimmune diseases. Jan 11, 2011

Pubmed Data : Am J Gastroenterol. 2011 Jan 11. Epub 2011 Jan 11. PMID: 11703168
Article Published Date : Jan 11, 2011
Study Type : Commentary
Additional Links
Diseases : Fever
Therapeutic Actions : Fasting/Caloric Restriction
[+]

Fasting inhibits hepatic stellate cells activation and potentiates anti-cancer activity of Sorafenib in hepatocellular cancer cells.Jan 31, 2018

Pubmed Data : J Cell Physiol. 2018 Feb ;233(2):1202-1212. Epub 2017 Jul 11. PMID: 28471474
Article Published Date : Jan 31, 2018
Study Type : In Vitro Study
Additional Links
Diseases : Lipopolysaccharide-Induced Toxicity, Liver Cancer
Therapeutic Actions : Fasting/Caloric Restriction
Pharmacological Actions : Antineoplastic Agents, Antiproliferative , Chemotherapeutic
Additional Keywords : Chemothapeutic Synergy: Sorafenib
[+]

Fasting regimens can reduce IGF-1, IGFBP1, glucose and insulin levels and consequently have beneficial effects on ovarian function.Jul 31, 2017

Pubmed Data : Med Hypotheses. 2017 Aug ;105:1-3. Epub 2017 Jun 23. PMID: 28735644
Article Published Date : Jul 31, 2017
Study Type : Review
Additional Links
Diseases : Polycystic Ovary Syndrome
Therapeutic Actions : Fasting/Caloric Restriction
[+]

Intermittent energy restriction may be an effective strategy for the treatment of overweight and obesity. Jan 31, 2018

Pubmed Data : JBI Database System Rev Implement Rep. 2018 Feb ;16(2):507-547. PMID: 29419624
Article Published Date : Jan 31, 2018
Study Type : Review
Additional Links
Diseases : Obesity
Therapeutic Actions : Fasting/Caloric Restriction
[+]

Intermittent fasting protects against Alzheimer’s disease possible through restoring aquaporin-4 polarity.Dec 31, 2016

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Front Mol Neurosci. 2017 ;10:395. Epub 2017 Nov 29. PMID: 29238290
Article Published Date : Dec 31, 2016
Study Type : In Vitro Study
Additional Links
Diseases : Alzheimer's Disease
Therapeutic Actions : Fasting/Caloric Restriction
Pharmacological Actions : Neuroprotective Agents
Additional Keywords : Alzheimer's disease, Fasting/Caloric Restriction, Neuroprotective Agents
[+]

Restriction in meal size and frequency may have a beneficial effect on neurological health and vulnerability to disease.Sep 01, 2009

Pubmed Data : Nutrition. 2009 Sep;25(9):964-72. Epub 2009 Mar 5. PMID: 12558961
Article Published Date : Sep 01, 2009
Study Type : Review
Additional Links
Therapeutic Actions : Fasting/Caloric Restriction
[+]

Resveratrol compares favorably to caloric restriction in extending the lifespan of Drosophila. Mar 15, 2011

Pubmed Data : Cell Cycle. 2011 Mar 15;10(6). Epub 2011 Mar 15. PMID: 21325893
Article Published Date : Mar 15, 2011
Study Type : In Vitro Study
Additional Links
Substances : Resveratrol
Diseases : Aging
Therapeutic Actions : Fasting/Caloric Restriction
[+]

Short-term fasting induces profound neuronal autophagyJul 31, 2010

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Autophagy. 2010 Aug ;6(6):702-10. Epub 2010 Aug 14. PMID: 20534972
Article Published Date : Jul 31, 2010
Study Type : In Vitro Study
Additional Links
Diseases : Neurodegenerative Diseases
Therapeutic Actions : Fasting/Caloric Restriction
Pharmacological Actions : Autophagy Up-regulation, Neurorestorative
[+]

The combination of caloric restriction along with anti-cancer drugs may suppress growth of tumor cells and enhance death of cancer cells.Nov 18, 2016

Pubmed Data : Biochim Biophys Acta. 2016 Nov 19 ;1867(1):29-41. Epub 2016 Nov 19. PMID: 27871964
Article Published Date : Nov 18, 2016
Study Type : Review
Additional Links
Diseases : Cancers: All
Therapeutic Actions : Fasting/Caloric Restriction
Pharmacological Actions : Chemotherapeutic
[+]

Therapeutic fasting has mood-enhancing and pain-relieving effects in chronic pain syndrome.Apr 01, 2010

Pubmed Data : Curr Pain Headache Rep. 2010 Apr;14(2):80-7. PMID: 20425196
Article Published Date : Apr 01, 2010
Study Type : Review
Additional Links
Diseases : Chronic Pain
Therapeutic Actions : Fasting/Caloric Restriction
[+]

This data suggests fasting and sorafenib as rational combination therapy for hepatocellular carcinoma.Jan 20, 2022

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Sci Adv. 2022 Jan 21 ;8(3):eabh2635. Epub 2022 Jan 21. PMID: 35061544
Article Published Date : Jan 20, 2022
Study Type : In Vitro Study
Additional Links
Diseases : Liver Cancer
Therapeutic Actions : Fasting/Caloric Restriction
Pharmacological Actions : Chemosensitizer
Additional Keywords : Chemothapeutic Synergy: Sorafenib
[+]

This reviews preclinical and preliminary studies on dietary restriction and fasting and their role in inducing cellular protection and chemotherapy resistance.Dec 31, 2015

Pubmed Data : Recent Results Cancer Res. 2016;207:241-66. PMID: 27557543
Article Published Date : Dec 31, 2015
Study Type : Review
Additional Links
Diseases : Cancers: All
Therapeutic Actions : Fasting/Caloric Restriction
Pharmacological Actions : Chemotherapeutic

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