Vaccine Adjuvants

Name	AC	CK
Vaccine-induced Toxicity	43	219
Autism Spectrum Disorders	41	211
Neurodevelopmental Disorders	25	207
Autism	17	122
Macrophagic myofasciitis	13	114
Mercury Poisoning	22	67
Tic Disorders	4	61
Aluminum Toxicity	15	58
Attention Deficit Disorder	4	51
Autoimmune Diseases	15	46
Autoimmune/inflammatory syndrome induced by adjuvants (ASIA)	14	46
Learning disorders	3	42
Mental Retardation	3	40
Attention Deficit Disorder with Hyperactivity	4	31
Cognitive Decline/Dysfunction	2	30
Speech Disorders	2	30
Oxidative Stress	9	24
Gulf War Syndrome	4	23
Inflammation	9	22
Developmental Disorder: Children	3	21
Childhood Chemical Exposures	1	20
Emotional Disorders	1	20
Immune Dysregulation: TH1/TH2 imbalance	1	20
Infant Mortality	1	20
Infantile Spasms	1	20
Seizures	1	20
Sexual Development: Dysfunctions and Abnormalities	1	20
Hypersensitivity	2	15
Mitochondrial Dysfunction	2	15
Infant Chemical Exposures	2	12
Kawasaki Disease	3	12
Anthrax	1	10
Ataxia: Cerebellar	1	10
Atopic Dermatitis	1	10
Atopic Disease	1	10
Atopic Hypersensitivity	1	10
Detoxification: Impaired	1	10
Infant Neurological Development	1	10
Obesity	1	10
Personality Disorder: Borderline	1	10
DNA damage	4	8
Neurodegenerative Diseases	4	8
Chronic Fatigue Syndrome	2	7
Pseudolymphoma	1	6
Systemic Lupus Erythematosus	2	6
Liver Damage	1	4
Prenatal Chemical Exposures	2	4
Central Nervous System Diseases	1	3
Deafness: Sudden	1	3
Dermatitis	1	3
Excitotoxicity	2	3
Formaldehyde Toxicity	1	3
Lichen Planus	1	3
Multiple Sclerosis	2	3
Myelodysplastic Syndrome	1	3
Postural Orthostatic Tachycardia Syndrome	1	3
Sjogren's Syndrome	2	3
Amygdala: Damage/Abnormalities	1	2
Anxiety Disorders	1	2
Arthritis	1	2
Brain Inflammation	1	2
Febrile Seizures	1	2
Human Papillomavirus (HPV)	1	2
Lupus Erythematosus: Systemic	1	2
Myopathies	1	2
Neurotoxicity	2	2
Social Behavior	1	2
Down Syndrome	1	1
Endothelial Damage	1	1
Fibromyalgia	1	1
Guillain-Barre Syndrome	1	1
Hydrogen Peroxide Induced Toxicity	1	1
Immune Disorders: Low Immune Function	1	1
Lymphoma	1	1
New Variant Creutzfeldt-Jakob Disease	1	1
vaccine injury	1	1

Name	AC	CK
Neurotoxic	38	214
Immunotoxic	11	50
Inflammatory	9	36
Endocrine Disruptor	2	22
Apoptotic	7	12
Genotoxic	3	11
Immunoreactive	5	10
Obesogenic	1	10
Hepatotoxic	1	4
Oxidant	4	4
Renotoxic	3	4
Cytotoxic	2	3
Carcinogenic	1	2
Hematoxic	1	2
Hemolytic	1	2
Immunosuppressive	1	2
Irritant	1	2
Tumorigenic	1	2
Cytotoxicity	1	1
Excitotoxic	1	1
Hypermethylation	1	1

Thimersol exposure is associated with tics and delayed language acquisition in infants.Nov 01, 2003

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Pubmed Data : Pediatrics. 2003 Nov;112(5):1039-48. PMID: 14595043

Adverse Pharmacological Actions : Neurotoxic

[+]

Aluminum hydroxide-induced macrophagic myofasciitis (MMF) associated with vaccination has been reported. Nov 01, 2011

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Pubmed Data : J Inorg Biochem. 2011 Nov ;105(11):1457-63. Epub 2011 Aug 22. PMID: 22099155

Article Published Date : Nov 01, 2011

Study Type : Human Study

Additional Links

Diseases : Macrophagic myofasciitis

Anti Therapeutic Actions : Vaccination: All

Problem Substances : Aluminum Hydroxide, Vaccine Adjuvants

[+]

Aluminum vaccine adjuvants appear to be contributing to the rising prevalence of autism.Oct 31, 2011

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Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : J Inorg Biochem. 2011 Nov ;105(11):1489-99. Epub 2011 Aug 23. PMID: 22099159

Article Published Date : Oct 31, 2011

Study Type : Human Study

Additional Links

Diseases : Aluminum Toxicity , Autism Spectrum Disorders

Additional Keywords : Diseases that are Linked

Anti Therapeutic Actions : Vaccination: All

Problem Substances : Vaccine Adjuvants

[+]

Aluminum vaccine adjuvants appear to contribute to the rising prevalence of autism.Nov 01, 2011

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Pubmed Data : J Inorg Biochem. 2011 Nov ;105(11):1489-99. Epub 2011 Aug 23. PMID: 22099159

Pubmed Data : Neurotoxicology. 2006 Sep ;27(5):685-92. Epub 2006 Aug 16. PMID: 16870260

Article Published Date : Aug 31, 2006

Study Type : Human Study

Additional Links

Diseases : Autism Spectrum Disorders

Problem Substances : Thimerosal

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High exposure to ethylmercury from thimerosal-containing vaccines in the first month of life increases the risk of subsequent development of neurologic development impairment.Dec 31, 1969

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Increasing organic Hg exposure from Thimerosal-containing vaccines increased the subsequent risk of pervasive developmental disorder diagnosis.Jan 31, 2015

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Pubmed Data : Biol Trace Elem Res. 2015 Feb ;163(1-2):28-38. Epub 2014 Nov 11. PMID: 25382662

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Pubmed Data : Brain Inj. 2017 Jan 19:1-7. Epub 2017 Jan 19. PMID: 28102704

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Pubmed Data : Int J Environ Res Public Health. 2014 Sep ;11(9):9156-70. Epub 2014 Sep 5. PMID: 25198681

Article Published Date : Aug 31, 2014

Study Type : Human Study

Additional Links

Diseases : Attention Deficit Disorder with Hyperactivity, Neurodevelopmental Disorders

Additional Keywords : Increased Risk

Problem Substances : Thimerosal

Adverse Pharmacological Actions : Neurotoxic

[+]

The association with DTwP vaccines and increased infant mortality in females may be due to vaccine adjuvants and Th2 polarizing effects.Jan 01, 2011

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Pubmed Data : J Trop Med. 2011 ;2011:706304. Epub 2011 May 5. PMID: 21760811

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These results provide a neurobiological substrate for brain dysfunction in aluminum hydroxide adjuvant-induced macrophagic myofasciitis patients.Dec 31, 2014

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Pubmed Data : PLoS One. 2015 ;10(6):e0128353. Epub 2015 Jun 1. PMID: 26030650

Article Published Date : Dec 31, 2014

Study Type : Human Study

Additional Links

Diseases : Aluminum Toxicity , Macrophagic myofasciitis , Vaccine-induced Toxicity

Problem Substances : Aluminum Hydroxide, Vaccine Adjuvants

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These results support the hypothesis that Hg sensitivity may be a heritable/genetic risk factor for autism spectrum disorders.Dec 31, 2010

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Pubmed Data : J Toxicol Environ Health A. 2011 ;74(18):1185-94. PMID: 21797771

Article Published Date : Dec 31, 2010

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Pubmed Data : Immunol Res. 2015 Feb ;61(1-2):90-6. PMID: 25381482

Article Published Date : Jan 31, 2015

Study Type : Human Study

Additional Links

Diseases : Autoimmune/inflammatory syndrome induced by adjuvants (ASIA), Inflammation

Anti Therapeutic Actions : Vaccination: HPV (Gardasil)

Problem Substances : Vaccine Adjuvants

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This study provides new evidence to confirm a significant relationship between exposure to thimerosal and increased diagnosis for delays in development.Jul 08, 2015

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Pubmed Data : J Epidemiol Glob Health. 2015 Jul 9. Epub 2015 Jul 9. PMID: 26166425

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Pubmed Data : Int J Toxicol. 2003 Jul-Aug;22(4):277-85. PMID: 12933322

Article Published Date : Jun 30, 2003

Study Type : Human Study

Additional Links

Diseases : Autism Spectrum Disorders, Detoxification: Impaired

Additional Keywords : Ethylmercury, Methylmercury

Problem Substances : Mercury, Thimerosal

[+]

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : J Toxicol. 2015 ;2015:573701. Epub 2015 Jan 21. PMID: 25688267

Article Published Date : Dec 31, 2014

Study Type : Human In Vitro

Additional Links

Diseases : Mitochondrial Dysfunction , Oxidative Stress

Additional Keywords : Genomic Variation

Problem Substances : Thimerosal

[+]

Peanut oil stimulates an immune response comparable to that of live measles vaccine. Dec 01, 1996

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Pubmed Data : Vaccine. 1996 Dec ;14(17-18):1703-6. PMID: 9032902

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Pubmed Data : J Cutan Med Surg. 2015 Sep-Oct;19(5):504-6. Epub 2015 Apr 15. PMID: 25876644

Article Published Date : Aug 31, 2015

Study Type : Human: Case Report

Additional Links

Diseases : Dermatitis, Formaldehyde Toxicity, Vaccine-induced Toxicity

Additional Keywords : Risk Factors

Anti Therapeutic Actions : Vaccination: Influenza

Problem Substances : Aspartame, Formaldehyde, Thimerosal

[+]

Thimerosal toxicity can lead to total limbal stem cell failure with secondary corneal vascularization and opacification.Jun 30, 2007

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Pubmed Data : Eye Contact Lens. 2007 Jul ;33(4):196-8. PMID: 17630628

Article Published Date : Jun 30, 2007

Study Type : Human: Case Report

Additional Links

Diseases : Mercury Poisoning

Problem Substances : Thimerosal

[+]

This report provides further documentation for a causal association linking the HBV vaccine with lichen planus.Dec 31, 2001

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Pubmed Data : Dermatology. 2002 ;205(2):166-8. PMID: 12218234

Article Published Date : Dec 31, 2001

Study Type : Human: Case Report

Additional Links

Diseases : Lichen Planus

Additional Keywords : Risk Factors

Anti Therapeutic Actions : Vaccination: Hepatitis B

Problem Substances : Thimerosal

[+]

A dose of 250 mg/kg/day of boric acid is associated with severe developmental toxicity in rabbits. Dec 01, 1996

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Pubmed Data : Fundam Appl Toxicol. 1996 Dec;34(2):176-87. PMID: 8954748

Article Published Date : Dec 01, 1996

Study Type : Animal Study

Additional Links

Problem Substances : Boric Acid

[+]

Pubmed Data : Neuromolecular Med. 2007;9(1):83-100. PMID: 17114826

Pubmed Data : Biomed Pharmacother. 2017 Feb ;86:381-392. Epub 2016 Dec 21. PMID: 28012393

Article Published Date : Jan 31, 2017

Study Type : Animal Study

Additional Links

Substances : Juniper

Diseases : Arthritis, Inflammation

Pharmacological Actions : Anti-Inflammatory Agents

Additional Keywords : Plant Extracts

Problem Substances : Freund adjuvant

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An oral route of administration for mercury is not comparable to an Intramuscular delivery.Dec 29, 2004

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Pubmed Data : Toxicol Lett. 2004 Dec 30 ;154(3):183-9. PMID: 15501610

Article Published Date : Dec 29, 2004

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Pubmed Data : Cerebellum. 2012 Jun ;11(2):575-86. PMID: 22015705

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Pubmed Data : Apoptosis. 2012 Jan 17. Epub 2012 Jan 17. PMID: 22249285

Article Published Date : Jan 17, 2012

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Pubmed Data : Toxicol Sci. 2004 Apr;78(2):222-8. Epub 2004 Jan 12. PMID: 14718649

Article Published Date : Apr 01, 2004

Study Type : Animal Study

Additional Links

Diseases : Autoimmune Diseases

Problem Substances : Adjuvant, Freund adjuvant, Hexadecane, Mineral Oil, Squalene

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Infant macaques retained significantly higher levels of elemental mercury in their brain tissue when exposed to thimerosal in infant vaccines versus methylmercury. Jul 31, 2005

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Article Publish Status : This is a free article. Click here to read the complete article.

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Pubmed Data : Acta Neurobiol Exp (Wars). 2010 ;70(2):147-64. PMID: 20628439

Article Published Date : Dec 31, 2009

Study Type : Animal Study

Additional Links

Diseases : Amygdala: Damage/Abnormalities, Neurodevelopmental Disorders, Vaccine-induced Toxicity

Anti Therapeutic Actions : Vaccination: All, Vaccination: Animal Model

Problem Substances : Thimerosal

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Neonatal administration of a vaccine preservative, thimerosal, produces lasting impairment of nociception and apparent activation of opioid system in rats.Dec 08, 2009

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Pubmed Data : Brain Res. 2009 Dec 8;1301:143-51. Epub 2009 Sep 9. PMID: 19747466

Article Published Date : Dec 08, 2009

Study Type : Animal Study

Additional Links

Problem Substances : Thimerosal

[+]

Neonatal exposure to thimerosal-containing vaccines might induce excitotoxic brain injuries, leading to neurodevelopmental disorders. DHEA may protect against mercury-induced neurotoxicity. Oct 21, 2011

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Pubmed Data : Neurochem Res. 2011 Oct 21. Epub 2011 Oct 21. PMID: 22015977

Article Published Date : Oct 21, 2011

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Pubmed Data : Clin Toxicol (Phila). 2006;44(3):249-53. PMID: 16749541

Article Published Date : Jan 01, 2006

Study Type : Animal Study

Additional Links

Problem Substances : Boric Acid

[+]

The antioxidant effect of melatonin revealed in this experiment is based on detoxification rather than common involvement in antioxidant barriers.Dec 31, 2014

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Pubmed Data : Acta Medica (Hradec Kralove). 2015 ;58(1):21-4. PMID: 26454803

Article Published Date : Dec 31, 2014

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There are lasting neuropathological changes in rat brain after intermittent neonatal administration of thimerosal.Jan 01, 2010

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Pubmed Data : Folia Neuropathol. 2010 ;48(4):258-69. PMID: 21225508

Article Published Date : Jan 01, 2010

Study Type : Animal Study

Additional Links

Diseases : Infant Chemical Exposures, Neurodegenerative Diseases, Vaccine-induced Toxicity

Problem Substances : Thimerosal

Adverse Pharmacological Actions : Neurotoxic

[+]

These findings implicate a genetic influence in autistic disorders and provides a model for investigating thimerosal related neurotoxicity.Aug 31, 2004

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Pubmed Data : Mol Psychiatry. 2004 Sep ;9(9):833-45. PMID: 15184908

Article Published Date : Aug 31, 2004

Study Type : Animal Study

Additional Links

Diseases : Autism Spectrum Disorders, Autoimmune Diseases, Neurodevelopmental Disorders

Additional Keywords : Genomic Variation

Problem Substances : Thimerosal

Adverse Pharmacological Actions : Neurotoxic

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These results indicate that embryonic exposure to thimerosal produces lasting impairment of brain monoaminergic system.Feb 28, 2013

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Pubmed Data : Brain Dev. 2013 Mar ;35(3):261-4. Epub 2012 Jun 1. PMID: 22658806

Article Published Date : Feb 28, 2013

Study Type : Animal Study

Additional Links

Diseases : Prenatal Chemical Exposures

Problem Substances : Thimerosal

Adverse Pharmacological Actions : Neurotoxic

[+]

Thimerosal had a proapoptotic effect on primary human lymphocytes at concentrations 100 times less to those contained in the multidose vaccine.Dec 31, 2013

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Pubmed Data : PLoS One. 2014 ;9(4):e92705. Epub 2014 Apr 1. PMID: 24690681

Article Published Date : Dec 31, 2013

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Pubmed Data : Behav Brain Res. 2011 Sep 30 ;223(1):107-18. Epub 2011 Apr 28. PMID: 21549155

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Pubmed Data : Med Hypotheses. 2001 Apr ;56(4):462-71. PMID: 11339848

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Pubmed Data : Mol Psychiatry. 2002 ;7 Suppl 2:S42-3. PMID: 12142947

Article Published Date : Dec 31, 2001

Study Type : Review

Additional Links

Diseases : Attention Deficit Disorder with Hyperactivity, Autism Spectrum Disorders

Additional Keywords : Ethylmercury, Genomic Variation, Methylmercury

Problem Substances : Mercury, Thimerosal

[+]

A review of the retention time of inorganic mercury in the brain.Jan 31, 2014

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[+]

Aluminium hydroxide and calcium phosphate adjuvants have a immunotoxic and haemolytic effects.Jan 01, 1993

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Pubmed Data : Vaccine. 1993;11(9):914-8. PMID: 8212836

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Pubmed Data : Toxicol Lett. 2010 Oct 5 ;198(2):182-90. Epub 2010 Jun 26. PMID: 20600710

Article Published Date : Oct 04, 2010

Study Type : In Vitro Study

Additional Links

Additional Keywords : Ethylmercury, Methylmercury

Problem Substances : Mercury, Thimerosal

Adverse Pharmacological Actions : Immunoreactive

[+]

Brain translocation of aluminum particles is linked to a trojan horse mechanism previously described for infectious particles.Dec 31, 2014

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Pubmed Data : Front Neurol. 2015 ;6:4. Epub 2015 Feb 5. PMID: 25699008

Article Published Date : Dec 31, 2014

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Pubmed Data : Toxicol In Vitro. 2007 Oct ;21(7):1258-61. Epub 2007 Aug 14. PMID: 17553660

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Pubmed Data : Yakugaku Zasshi. 2011 ;131(12):1723-31. PMID: 22129866

Article Published Date : Jan 01, 2011

Study Type : Review

Additional Links

Diseases : Aluminum Toxicity , Febrile Seizures, Vaccine-induced Toxicity

Problem Substances : Aluminum Hydroxide, Vaccine Adjuvants

[+]

Click here to read the entire abstract

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Pubmed Data : J Biol Chem. 2008 May 2 ;283(18):11913-23. Epub 2008 Mar 4. PMID: 18321861

Article Published Date : May 01, 2008

Study Type : In Vitro Study

Additional Links

Diseases : Autism Spectrum Disorders, Mercury Poisoning

Problem Substances : Mercury, Thimerosal

[+]

Lactic acid triggers, in vitro, thiomersal to degrade protein in the presence of PLGA microspheres.Mar 31, 2004

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Pubmed Data : Int J Pharm. 2004 Apr 1 ;273(1-2):1-8. PMID: 15010124

Article Published Date : Mar 31, 2004

Study Type : In Vitro Study

Additional Links

Problem Substances : Thimerosal

[+]

Low-dose mercury exposure in early life: relevance of thimerosal to fetuses, newborns and infants.Dec 31, 2012

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Pubmed Data : Curr Med Chem. 2013 ;20(32):4060-9. PMID: 23992327

Article Published Date : Dec 31, 2012

Study Type : Review

Additional Links

Diseases : Vaccine-induced Toxicity

Additional Keywords : Risk Factors

Problem Substances : Thimerosal

[+]

Low-dose thimerosal is still used in infants vaccines.Aug 31, 2018

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Pubmed Data : J Trace Elem Med Biol. 2018 Sep ;49:134-139. Epub 2018 May 17. PMID: 29895363

Article Published Date : Aug 31, 2018

Study Type : Review

Additional Links

Problem Substances : Thimerosal

[+]

[+]

More research attention has been given to EtHg and findings have showed a solid link with neurotoxic effects in humans.Jan 31, 2015

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Pubmed Data : Int J Environ Res Public Health. 2015 Feb ;12(2):1295-313. Epub 2015 Jan 23. PMID: 25625408

Article Published Date : Jan 31, 2015

Study Type : Review

Additional Links

Additional Keywords : Synergistic Toxicity

Problem Substances : Aluminum, Thimerosal

[+]

Natural immunomodulators represent a potentially important way of blocking or partly restoring the immunosuppression of toxins such as mercury.Oct 31, 2012

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Pubmed Data : Toxins (Basel). 2012 Nov ;4(11):1301-8. Epub 2012 Nov 9. PMID: 23202317

Article Published Date : Oct 31, 2012

Study Type : Review

Additional Links

Substances : Resveratrol, Stilbenes, Vitamin C

Pharmacological Actions : Cytoprotective

Problem Substances : Thimerosal

Adverse Pharmacological Actions : Immunotoxic

[+]

Neurological adverse events associated with vaccination.May 31, 2002

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Pubmed Data : Curr Opin Neurol. 2002 Jun ;15(3):333-8. PMID: 12045734

Article Published Date : May 31, 2002

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Pubmed Data : Toxicol In Vitro. 2004 Oct ;18(5):563-9. PMID: 15251173

Article Published Date : Sep 30, 2004

Study Type : In Vitro Study

Additional Links

Diseases : Hydrogen Peroxide Induced Toxicity, Oxidative Stress

Problem Substances : Thimerosal

Adverse Pharmacological Actions : Apoptotic

[+]

The FDA announced in 1999 that infants who had multiple vaccines with thimerosal may have been exposed to cumulative Hg in excess of federal safety guidelines.Sep 30, 2001

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Pubmed Data : Neurotoxicology. 2001 Oct ;22(5):691-7. PMID: 11770890

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Pubmed Data : J Trace Elem Med Biol. 2016 Sep ;37:8-24. Epub 2016 Jun 2. PMID: 27473827

Article Published Date : Aug 31, 2016

Study Type : Review

Additional Links

Diseases : Autism Spectrum Disorders

Problem Substances : Thimerosal

[+]

The putative role of environmental mercury in the pathogenesis and pathophysiology of autism spectrum disorders and subtypes.May 31, 2018

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Pubmed Data : Mol Neurobiol. 2018 Jun ;55(6):4834-4856. Epub 2017 Jul 22. PMID: 28733900

Article Published Date : May 31, 2018

Study Type : Review

Additional Links

Diseases : Autism Spectrum Disorders

Additional Keywords : Ethylmercury

Anti Therapeutic Actions : Vaccination: All

Problem Substances : Mercury, Thimerosal

[+]

The reduction of MT-1 mRNA level by thiosalicylate may affect the proliferation of C8-B4 cells.Jun 29, 2009

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Pubmed Data : Toxicology. 2009 Jun 30 ;261(1-2):25-32. Epub 2009 Apr 19. PMID: 19386279

Article Published Date : Jun 29, 2009

Study Type : In Vitro Study

Additional Links

Problem Substances : Thimerosal

[+]

The results of this study suggest that ethylmercury is a mitochondrial toxin in human astrocytes. Dec 31, 2011

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Pubmed Data : J Toxicol. 2012 ;2012:373678. Epub 2012 Jun 28. PMID: 22811707

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There are several case reports of autoimmune diseases following vaccines.Sep 30, 2015

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Pubmed Data : Pharmacol Res. 2015 Oct ;100:190-209. Epub 2015 Aug 12. PMID: 26275795

Article Published Date : Sep 30, 2015

Study Type : Review

Additional Links

Diseases : Autoimmune Diseases, Vaccine-induced Toxicity

Problem Substances : Aluminum, Vaccine Adjuvants

[+]

There is a biological basis for mercury-induced autism spectrum disorders and the sexual dimorphism associated with disease prevalence.Jan 01, 2010

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Pubmed Data : Acta Neurobiol Exp (Wars). 2010;70(2):209-26. PMID: 20628444

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Pubmed Data : J Physiol Pharmacol. 2010 Dec ;61(6):753-8. PMID: 21224507

Article Published Date : Nov 30, 2010

Study Type : In Vitro Study

Additional Links

Problem Substances : Thimerosal

Adverse Pharmacological Actions : Neurotoxic

[+]

Thimerosal at 30 microM induced an apoptotic change in membranes of almost all living cells. Feb 28, 2005

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Pubmed Data : Toxicol In Vitro. 2005 Mar ;19(2):191-8. PMID: 15649632

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Pubmed Data : Toxicol Sci. 2003 Aug ;74(2):361-8. Epub 2003 Aug 28. PMID: 12773768

Article Published Date : Jul 31, 2003

Study Type : In Vitro Study

Additional Links

Diseases : DNA damage

Problem Substances : Thimerosal

Adverse Pharmacological Actions : Apoptotic, Neurotoxic

[+]

Thimerosal induces S phase arrest and causes apoptosis in C2C12 myoblast cells.Dec 31, 2011

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Pubmed Data : Biochim Biophys Acta. 2002 Dec 16 ;1593(1):9-15. PMID: 12431779

Article Published Date : Dec 15, 2002

Study Type : In Vitro Study

Additional Links

Problem Substances : Thimerosal

Adverse Pharmacological Actions : Oxidant

[+]

Thiol reagent thimerosal-induced Ca2+ mobilization in isolated guinea pig cochlear outer hair cells.May 31, 2000

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Pubmed Data : Zhonghua Er Bi Yan Hou Ke Za Zhi. 2000 Jun ;35(3):192-5. PMID: 12768775

Article Published Date : May 31, 2000

Study Type : In Vitro Study

Additional Links

Problem Substances : Thimerosal

[+]

Thiomersal and ethylmercury could significantly inhibit the thioredoxin system in vitro. Jul 31, 2015

Uptake of particulate vaccine adjuvants (e.g. nanoparticle polystyrene) by dendritic cells activates the NALP3 inflammasome.Jan 20, 2009

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Pubmed Data : Proc Natl Acad Sci U S A. 2009 Jan 20 ;106(3):870-5. Epub 2009 Jan 12. PMID: 19139407

Article Published Date : Jan 20, 2009

Study Type : In Vitro Study

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As thimerosal was removed from childhood vaccines, the number of neurodevelopmental disorders decreased in the US.Jun 01, 2006

Exposure to mercury from thimerosal-containing vaccines was associcated with an increased risk of neurodevelopmental problems in infants from 1992-1997.Apr 01, 2005

Rates of autism, speech disorders, mental retardation, infantile spasms, and thinking abnormalities were higher in children exposured to higher thimerosal levels.Aug 01, 2006

Thimerosal exposure is associated with increasing trends of premature puberty in 278,624 subjects from 1990-1996.Apr 01, 2010

Thimersol exposure in infants is associated with an increase risk for tics. Sep 01, 2004

Thimersol exposure in infants significantly increases neurodevelopment disorders in infants, e.g. autism, autism spectrum disorders, tics, attention deficit disorder, and emotional disturbances.Aug 15, 2008

Thimersol exposure is associated with tics and delayed language acquisition in infants.Nov 01, 2003

2001: Depending on the immunization schedule, vaccine formulation, and infant weight, cumulative exposure of infants to mercury from thimerosal during the first 6 months of life may exceed EPA guidelines.May 01, 2001

A meta-analysis reveals that thimerosal containing vaccines significantly increase the risk of neurodevelopmental disorders.Aug 01, 2006

A subpopulation of eight individuals from four of the families showed thimerosal hypersensitivity.Dec 31, 2012

Administration of thimerosal-containing vaccines in the United States resulted in a significant number of children developing neurodevelopmental disorders.Nov 01, 2004

Adverse events following immunization with vaccines containing adjuvants.Jun 30, 2013

Aluminum hydroxide injections lead to motor deficits and motor neuron degeneration.Nov 01, 2009

Aluminum hydroxide-induced macrophagic myofasciitis (MMF) associated with vaccination has been reported. Nov 01, 2011

Aluminum vaccine adjuvants appear to be contributing to the rising prevalence of autism.Oct 31, 2011

Aluminum vaccine adjuvants appear to contribute to the rising prevalence of autism.Nov 01, 2011

Autoimmune/inflammatory syndrome induced by adjuvants (Shoenfeld's syndrome): clinical and immunological spectrum.Mar 31, 2013

Boys vaccinated as neonates had threefold greater odds for autism diagnosis compared to boys never vaccinated or vaccinated after the first month of life. Dec 31, 2009

Children with autism were twice as likely as non-autistic controls to be born from mothers who had Rh incompatibilities with the developing fetus during pregnancy. Apr 30, 2007

Coinciding with the largest increase of thimerosal in vaccines given to infants in America, the rates of Kawasaki's Disease increased.Dec 31, 2007

Cultured lymphocytes from autistic children and non-autistic siblings up-regulate heat shock protein RNA in response to thimerosal challenge.Aug 31, 2006

High exposure to ethylmercury from thimerosal-containing vaccines in the first month of life increases the risk of subsequent development of neurologic development impairment.Dec 31, 1969

In the present study, intracytoplasmic inclusions were constantly detected in macrophages of the MMF lesions and were shown to contain aluminium by three different methods.Aug 31, 2001

In this reanalysis data shows that a statistically significant link appears between blood mercury levels and autistic disorder in children.Oct 31, 2007

Increased organic mercury exposure from Thimerosal-containing hepatitis B vaccines could lead to an increased risk of obesity diagnosis.Jun 30, 2016

Increasing organic Hg exposure from Thimerosal-containing vaccines increased the subsequent risk of pervasive developmental disorder diagnosis.Jan 31, 2015

Long-term persistence of vaccine-derived aluminum hydroxide within the body assessed by MMF is associated with cognitive dysfunction.Oct 31, 2009

Macrophagic myofasciitis in children is a localized reaction to vaccination.May 31, 2008

Mercury exposure from thimerosal containing childhood vaccines raised the subsequent risk of atypical autism diagnosis.Jun 30, 2017

Mercury exposure from thimerosal containing childhood vaccines raised the subsequent risk of diagnosis of emotional disturbances.Jan 18, 2017

Mercury exposure from thimerosal is significantly associated with the ACSDs of ASD, TD, and ADD/ADHD.Dec 31, 2016

Mercury levels are 1.9 times higher in subjects diagnosed with autism spectrum disorders.Jan 01, 2010

Mothers receiving thimerosal via Rho(D) immune globulin injection saw a significantly higher rate of autism in the children exposed to mercury in utero. Mar 31, 2008

Organic-Hg exposure from thimerosal-containing hepatitis B vaccine led to an increased risk of neurodevelopmental disorder diagnosis.Aug 31, 2014

The association with DTwP vaccines and increased infant mortality in females may be due to vaccine adjuvants and Th2 polarizing effects.Jan 01, 2011

The occurrence of neurodevelopmental disorders following thimerosal-containing childhood vaccines does not appear to be coincidental.Mar 31, 2003

The vaccine adjuvant squalene in anthrax vaccines given to soldiers in the Gulf War resulted in the formation of antibodies to squalene which are associated with Gulf War Syndrome.Feb 01, 2011

The vaccines containing the adjuvant aluminium hydroxide may trigger macrophagic myofasciitis in some patients.Dec 31, 2014

There is an association between neurodevelopmental disorders and thimerosal-containing vaccines.Jun 01, 2003

There is evidence supporting an association between increasing organic-Hg exposure from Thimerosal-containing childhood vaccines and the subsequent risk of an ASD. Dec 31, 2012

These results provide a neurobiological substrate for brain dysfunction in aluminum hydroxide adjuvant-induced macrophagic myofasciitis patients.Dec 31, 2014

These results support the hypothesis that Hg sensitivity may be a heritable/genetic risk factor for autism spectrum disorders.Dec 31, 2010

Thimerosal containing vaccines may cause atopy in children. Feb 01, 1999

This study found a significant increase in neurodevelopmental delays related to the combined exposure to methylmercury and ethylmercury.Jan 06, 2016

This study presents the first systematic estimation of ASIA incidence and expands the knowledge on this pathology.Jan 31, 2015

This study provides new evidence to confirm a significant relationship between exposure to thimerosal and increased diagnosis for delays in development.Jul 08, 2015

This study provides suggestive evidence of an association between thimerosal and neurodevelopmental outcomes.Mar 13, 2018

This study reveals that the risk of autism significantly decreased with reductions in mercury exposure from thimerosal containing childhood vaccines.Dec 28, 2016

This study shows that autistic children had significantly reduced excretion levels of mercury via hair than the control group. Jun 30, 2003

This study supports an association between increasing exposure from thimerosal containing childhood vaccines and the subsequent risk of specific delays in development among males and females.Sep 30, 2014

This was a case study in which 3 patients with autoimmune/auto-inflammatory syndrome induced by adjuvants (ASIA) after quadrivalent human papillomavirus vaccination (HPV).May 10, 2015

Vaccines with Thimerosal led to more adverse events in this study. Dec 31, 2014

Findings suggest that the epidemiological link between environmental mercury exposure and an increased risk of developing autism may be mediated through mitochondrial dysfunction.Dec 31, 2014

Peanut oil stimulates an immune response comparable to that of live measles vaccine. Dec 01, 1996

These data raises some concern on the widespread use of thimerosal.Dec 31, 2002

These results alert about the ex-vivo immunomodulatory effects of thimerosal on dendritic cells.Dec 31, 2013

These results indicate the genotoxic and cytotoxic effect of thimerosal in cultured human peripheral blood lymphocytes.May 31, 2008

Thimerosal at low nanomolar concentrations was able to induce significant cellular toxicity in human neuron and fetal cells.May 31, 2009

Thimerosal induces antiproliferative properties, apoptosis, and autophagy activation in human Chang conjunctival cells.Jan 31, 2014

The pathogenic role of aluminium hydroxide is now recognized by the presence of chronic fatigue syndrome, macrophagic myofasciitis and subcutaneous pseudolymphoma, linked to intramuscular injection of aluminium hydroxide-containing vaccines.Mar 14, 2012

A case of a 14-year-old girl who developed postural orthostatic tachycardia syndrome with chronic fatigue 2 months following Gardasil vaccination.Dec 31, 2013

A case of hypersensitivity reaction, myelodysplastic syndrome and pancytopenia, which developed after an thimerosal-containing tetanus vaccine.Nov 30, 2007

A case report of bilateral deafness two days following influenza vaccination.Aug 16, 2018

A series of case studies demonstrate that thimerosal exposure is a major contributing factor to the pathogenesis of autism spectrum disorders.May 15, 2007

A sudden onset of a pseudo-neurological syndrome after HPV-16/18 AS04-adjuvated vaccine.Nov 30, 2014

Central nervous system disease in patients with macrophagic myofasciitis.Apr 30, 2001

Pediatric Wells syndrome (eosinophilic cellulitis) after vaccination.Aug 31, 2018

Systemic allergic contact dermatitis after formaldehyde-containing influenza vaccination.Aug 31, 2015

Thimerosal toxicity can lead to total limbal stem cell failure with secondary corneal vascularization and opacification.Jun 30, 2007

This report provides further documentation for a causal association linking the HBV vaccine with lichen planus.Dec 31, 2001

A dose of 250 mg/kg/day of boric acid is associated with severe developmental toxicity in rabbits. Dec 01, 1996

A gender-selective toxicity of thimerosal was observed; this finding is relevant to autism spectrum diagnosis prevalence among males and females.Feb 28, 2009

Vaccine Adjuvants

View the Evidence:
247 Abstracts with Vaccine Adjuvants Research